Abstract 4368

Objective

To investigate the effect of allogeneic transplantation in treating primary granulocytic sarcoma.

Methods

We report the diagnosis and treatment of one patient with primary granulocytic sarcoma and review the related articles.

Results

Firstly appeared as one isolated tumor in breast, the disease was diagnosed by pathological methods with immunochemistry positive stain in MPO, CD68(KP-1) and bacteriolysis enzyme. After radical operation on sick breast, the patient was treated with four courses chemotherapy according to that of acute granulocytic leukemia,then followed by matched sibling transplantation. After 6 months follow-up, the patients is still in complete remission.

Conclusion

If having suitable donor, patient with primary granulocytic sarcoma shoud be treated with allogeneic transplantation.

Disclosures:

No relevant conflicts of interest to declare.

Topics:
allopurinol, granulocytic sarcoma, transplantation, transplantation, homologous, cd68 antigen, human, chemotherapy regimen, complete remission, enzymes, follow-up, leukemia, myelocytic, acute

Author notes

*

Asterisk with author names denotes non-ASH members.

© 2009 by The American Society of Hematology
2009
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