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Journal Articles

The clinical and functional effects of TERT variants in myelodysplastic syndrome

Christopher R. Reilly, Mikko Myllymäki, Robert Redd, Shilpa Padmanaban, Druha Karunakaran, Valerie Tesmer, Frederick D. Tsai, Christopher J. Gibson, Huma Q. Rana, Liang Zhong, Wael Saber, Stephen R. Spellman, Zhen-Huan Hu, Esther H. Orr, Maxine M. Chen, Immaculata De Vivo, Daniel J. DeAngelo, Corey Cutler, Joseph H. Antin, Donna Neuberg, Judy E. Garber, Jayakrishnan Nandakumar, Suneet Agarwal, R. Coleman Lindsley
Journal: Blood
Blood (2021) 138 (10): 898–911.
https://doi.org/10.1182/blood.2021011075
Published: 2021
Includes: Supplemental data
Journal Articles

The journey of a thousand miles begins with 1 step

Luca Malcovati
Journal: Blood
Blood (2021) 138 (10): 824–826.
https://doi.org/10.1182/blood.2021012304
Published: 2021
Journal Articles

HLA-haploidentical vs matched unrelated donor transplants with posttransplant cyclophosphamide-based prophylaxis

Mahasweta Gooptu, Rizwan Romee, Andrew St. Martin, Mukta Arora, Monzr Al Malki, Joseph H. Antin, Christopher N. Bredeson, Claudio G. Brunstein, Saurabh Chhabra, Ephraim J. Fuchs, Nilanjan Ghosh, Michael R. Grunwald, Christopher G. Kanakry, Natasha Kekre, Jospeh P. McGuirk, Ian K. McNiece, Rohtesh S. Mehta, Marco Mielcarek, Fillipo Milano, Dipenkumar Modi, Ran Reshef, Scott R. Solomon, Mark A. Schroeder, Edmund K. Waller, Yoshiro Inamoto, Robert J. Soiffer, Mary Eapen
Journal: Blood
Blood (2021) 138 (3): 273–282.
https://doi.org/10.1182/blood.2021011281
Published: 2021
Journal Articles

Up-front carfilzomib, lenalidomide, and dexamethasone with transplant for patients with multiple myeloma: the IFM KRd final results

Clinical Trials & Observations
Murielle Roussel, Valerie Lauwers-Cances, Soraya Wuilleme, Karim Belhadj, Salomon Manier, Laurent Garderet, Martine Escoffre-Barbe, Clara Mariette, Lotfi Benboubker, Denis Caillot, Cécile Sonntag, Cyrille Touzeau, Jehan Dupuis, Philippe Moreau, Xavier Leleu, Thierry Facon, Benjamin Hébraud, Jill Corre, Michel Attal
Journal: Blood
Blood (2021) 138 (2): 113–121.
https://doi.org/10.1182/blood.2021010744
Published: 2021
Journal Articles

Oral ixazomib, lenalidomide, and dexamethasone for transplant-ineligible patients with newly diagnosed multiple myeloma

Clinical Trials & Observations
Thierry Facon, Christopher P. Venner, Nizar J. Bahlis, Fritz Offner, Darrell J. White, Lionel Karlin, Lotfi Benboubker, Sophie Rigaudeau, Philippe Rodon, Eric Voog, Sung-Soo Yoon, Kenshi Suzuki, Hirohiko Shibayama, Xiaoquan Zhang, Philip Twumasi-Ankrah, Godwin Yung, Robert M. Rifkin, Philippe Moreau, Sagar Lonial, Shaji K. Kumar, Paul G. Richardson, S. Vincent Rajkumar
Journal: Blood
Blood (2021) 137 (26): 3616–3628.
https://doi.org/10.1182/blood.2020008787
Published: 2021
Includes: Supplemental data
Journal Articles

Radiation-induced bystander effects impair transplanted human hematopoietic stem cells via oxidative DNA damage

Linping Hu, Xiuxiu Yin, Yawen Zhang, Aiming Pang, Xiaowei Xie, Shangda Yang, Caiying Zhu, Yapu Li, Biao Zhang, Yaojin Huang, Yunhong Tian, Mei Wang, Wenbin Cao, Shulian Chen, Yawei Zheng, Shihui Ma, Fang Dong, Sha Hao, Sizhou Feng, Yongxin Ru, Hui Cheng, Erlie Jiang, Tao Cheng
Journal: Blood
Blood (2021) 137 (24): 3339–3350.
https://doi.org/10.1182/blood.2020007362
Published: 2021
Includes: Supplemental data
Journal Articles

Expect the unexpected

Didier Blaise
Journal: Blood
Blood (2021) 137 (23): 3163–3164.
https://doi.org/10.1182/blood.2021011368
Published: 2021
Journal Articles

Posttransplant cyclophosphamide is associated with increased cytomegalovirus infection: a CIBMTR analysis

Clinical Trials & Observations
Scott R. Goldsmith, Muhammad Bilal Abid, Jeffery J. Auletta, Asad Bashey, Amer Beitinjaneh, Paul Castillo, Roy F. Chemaly, Min Chen, Stefan Ciurea, Christopher E. Dandoy, Miguel Ángel Díaz, Ephraim Fuchs, Siddhartha Ganguly, Christopher G. Kanakry, Jennifer A. Kanakry, Soyoung Kim, Krishna V. Komanduri, Maxwell M. Krem, Hillard M. Lazarus, Hongtao Liu, Per Ljungman, Richard Masiarz, Carolyn Mulroney, Sunita Nathan, Taiga Nishihori, Kristin M. Page, Miguel-Angel Perales, Randy Taplitz, Rizwan Romee, Marcie Riches
Journal: Blood
Blood (2021) 137 (23): 3291–3305.
https://doi.org/10.1182/blood.2020009362
Published: 2021
Includes: Supplemental data
Journal Articles

Molecular and cellular features of CTLA-4 blockade for relapsed myeloid malignancies after transplantation

Clinical Trials & Observations Brief Report
Livius Penter, Yi Zhang, Alexandra Savell, Teddy Huang, Nicoletta Cieri, Emily M. Thrash, Seunghee Kim-Schulze, Aashna Jhaveri, Jingxin Fu, Srinika Ranasinghe, Shuqiang Li, Wandi Zhang, Emma S. Hathaway, Matthew Nazzaro, Haesook T. Kim, Helen Chen, Magdalena Thurin, Scott J. Rodig, Mariano Severgnini, Carrie Cibulskis, Stacey Gabriel, Kenneth J. Livak, Corey Cutler, Joseph H. Antin, Sarah Nikiforow, John Koreth, Vincent T. Ho, Philippe Armand, Jerome Ritz, Howard Streicher, Donna Neuberg, F. Stephen Hodi, Sacha Gnjatic, Robert J. Soiffer, X. Shirley Liu, Matthew S. Davids, Pavan Bachireddy, Catherine J. Wu
Journal: Blood
Blood (2021) 137 (23): 3212–3217.
https://doi.org/10.1182/blood.2021010867
Published: 2021
Includes: Supplemental data
Journal Articles

Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells

Brief Report
Pia Sommerkamp, Mari Carmen Romero-Mulero, Andreas Narr, Luisa Ladel, Lucie Hustin, Katharina Schönberger, Simon Renders, Sandro Altamura, Petra Zeisberger, Karin Jäcklein, Daniel Klimmeck, Alejo Rodriguez-Fraticelli, Fernando D. Camargo, Leïla Perié, Andreas Trumpp, Nina Cabezas-Wallscheid
Journal: Blood
Blood (2021) 137 (23): 3218–3224.
https://doi.org/10.1182/blood.2020007876
Published: 2021
Includes: Supplemental data
Journal Articles

Shah NN, Ahn KW, Litovich C, et al. Is autologous transplant in relapsed DLBCL patients achieving only a PET + PR appropriate in the CAR T-cell era? Blood . 2021;137(10):1416-1423.

Journal: Blood
Blood (2021) 137 (20): 2854–2855.
https://doi.org/10.1182/blood.2021011979
Published: 2021
Journal Articles

Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells

Suk See De Ravin, Julie Brault, Ronald J. Meis, Siyuan Liu, Linhong Li, Mara Pavel-Dinu, Cicera R. Lazzarotto, Taylor Liu, Sherry M. Koontz, Uimook Choi, Colin L. Sweeney, Narda Theobald, GaHyun Lee, Aaron B. Clark, Sandra S. Burkett, Benjamin P. Kleinstiver, Matthew H. Porteus, Shengdar Tsai, Douglas B. Kuhns, Gary A. Dahl, Stephen Headey, Xiaolin Wu, Harry L. Malech
Journal: Blood
Blood (2021) 137 (19): 2598–2608.
https://doi.org/10.1182/blood.2020008503
Published: 2021
Includes: Supplemental data
Journal Articles

A randomized phase 3 trial of autologous vs allogeneic transplantation as part of first-line therapy in poor-risk peripheral T-NHL

Clinical Trials & Observations
Norbert Schmitz, Lorenz Truemper, Krimo Bouabdallah, Marita Ziepert, Mathieu Leclerc, Guillaume Cartron, Arnaud Jaccard, Peter Reimer, Eva Wagner, Martin Wilhelm, Laurence Sanhes, Thierry Lamy, Laurence de Leval, Andreas Rosenwald, Muriel Roussel, Frank Kroschinsky, Walter Lindemann, Peter Dreger, Andreas Viardot, Noël Milpied, Christian Gisselbrecht, Gerald Wulf, Emmanuel Gyan, Philippe Gaulard, Jacques Olivier Bay, Bertram Glass, Viola Poeschel, Gandhi Damaj, David Sibon, Alain Delmer, Karin Bilger, Anne Banos, Mathias Haenel, Martin Dreyling, Bernd Metzner, Ulrich Keller, Friederike Braulke, Birte Friedrichs, Maike Nickelsen, Bettina Altmann, Olivier Tournilhac
Journal: Blood
Blood (2021) 137 (19): 2646–2656.
https://doi.org/10.1182/blood.2020008825
Published: 2021
Includes: Supplemental data
Journal Articles

Obinutuzumab vs rituximab for advanced DLBCL: a PET-guided and randomized phase 3 study by LYSA

Clinical Trials & Observations
Steven Le Gouill, Hervé Ghesquières, Lucie Oberic, Franck Morschhauser, Hervé Tilly, Vincent Ribrag, Thierry Lamy, Catherine Thieblemont, Hervé Maisonneuve, Rémy Gressin, Krimo Bouhabdallah, Corinne Haioun, Gandhi Damaj, Luc Fornecker, Réda Bouhabdallah, Pierre Feugier, David Sibon, Guillaume Cartron, Christophe Bonnet, Marc André, Loic Chartier, Philippe Ruminy, Françoise Kraeber-Bodéré, Caroline Bodet-Milin, Alina Berriolo-Riedinger, Josette Brière, Jean-Philippe Jais, Thierry Jo Molina, Emmanuel Itti, René-Olivier Casasnovas
Journal: Blood
Blood (2021) 137 (17): 2307–2320.
https://doi.org/10.1182/blood.2020008750
Published: 2021
Includes: Supplemental data
Journal Articles

JAK2 -V617F and interferon-α induce megakaryocyte-biased stem cells characterized by decreased long-term functionality

Tata Nageswara Rao, Nils Hansen, Jan Stetka, Damien Luque Paz, Milena Kalmer, Julian Hilfiker, Max Endele, Nouraiz Ahmed, Lucia Kubovcakova, Margareta Rybarikova, Hui Hao-Shen, Florian Geier, Christian Beisel, Stefan Dirnhofer, Timm Schroeder, Tim H. Brümmendorf, Dominik Wolf, Steffen Koschmieder, Radek C. Skoda
Journal: Blood
Blood (2021) 137 (16): 2139–2151.
https://doi.org/10.1182/blood.2020005563
Published: 2021
Includes: Supplemental data
Journal Articles

A phase 3 double-blind study of the addition of tocilizumab vs placebo to cyclosporin/methotrexate GVHD prophylaxis

Clinical Trials & Observations
Glen A. Kennedy, Siok-Keen Tey, Luke Buizen, Antiopi Varelias, Kate H. Gartlan, Cameron Curley, Stuart D. Olver, Karshing Chang, Jason P. Butler, Ashish Misra, Elango Subramoniapillai, A. James Morton, Simon Durrant, Andrea S. Henden, John Moore, David Ritchie, David Gottlieb, Julian Cooney, Sanjoy K. Paul, Geoffrey R. Hill
Journal: Blood
Blood (2021) 137 (14): 1970–1979.
https://doi.org/10.1182/blood.2020009050
Published: 2021
Includes: Supplemental data
Journal Articles

STING and transplantation: can targeting this pathway improve outcomes?

Cameron S. Bader, Lei Jin, Robert B. Levy
Journal: Blood
Blood (2021) 137 (14): 1871–1878.
https://doi.org/10.1182/blood.2020008911
Published: 2021
Journal Articles

Long-term neurodevelopmental outcomes of hematopoietic stem cell transplantation for late-infantile Krabbe disease

Clinical Trials & Observations
Isabel C. Yoon, Nicholas A. Bascou, Michele D. Poe, Paul Szabolcs, Maria L. Escolar
Journal: Blood
Blood (2021) 137 (13): 1719–1730.
https://doi.org/10.1182/blood.2020005477
Published: 2021
Includes: Supplemental data
Journal Articles

Fecal microbiota diversity disruption and clinical outcomes after auto-HCT: a multicenter observational study

Niloufer Khan, Sarah Lindner, Antonio L. C. Gomes, Sean M. Devlin, Gunjan L. Shah, Anthony D. Sung, Craig S. Sauter, Heather J. Landau, Parastoo B. Dahi, Miguel-Angel Perales, David J. Chung, Alexander M. Lesokhin, Anqi Dai, Annelie Clurman, John B. Slingerland, Ann E. Slingerland, Daniel G. Brereton, Paul A. Giardina, Molly Maloy, Gabriel K. Armijo, Carlos Rondon-Clavo, Emily Fontana, Lauren Bohannon, Sendhilnathan Ramalingam, Amy T. Bush, Meagan V. Lew, Julia A. Messina, Eric Littmann, Ying Taur, Robert R. Jenq, Nelson J. Chao, Sergio Giralt, Kate A. Markey, Eric G. Pamer, Marcel R. M. van den Brink, Jonathan U. Peled
Journal: Blood
Blood (2021) 137 (11): 1527–1537.
https://doi.org/10.1182/blood.2020006923
Published: 2021
Includes: Supplemental data
Journal Articles

Is autologous transplant in relapsed DLBCL patients achieving only a PET + PR appropriate in the CAR T-cell era?

Nirav N. Shah, Kwang W. Ahn, Carlos Litovich, Yizeng He, Craig Sauter, Timothy S. Fenske, Mehdi Hamadani
Journal: Blood
Blood (2021) 137 (10): 1416–1423.
https://doi.org/10.1182/blood.2020007939
Published: 2021
Includes: Supplemental data