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Volume 88, Issue 7

October 1 1996

In this Issue

EDITORIALS
REVIEW
ARTICLES
PHOTOGRAPHS
LETTER
ERRATUM

EDITORIALS

The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype [editorial; comment]

JV Melo

View Articletitled, The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype [editorial; comment]

REVIEW

Mycosis fungoides and Sezary syndrome [see comments]

E Diamandidou,PR Cohen,R Kurzrock

View Articletitled, Mycosis fungoides and Sezary syndrome [see comments]

ARTICLES

Neutrophilic-chronic myeloid leukemia: a distinct disease with a specific molecular marker (BCR/ABL with C3/A2 junction) [see comments]

F Pane,F Frigeri,M Sindona,L Luciano,F Ferrara,R Cimino,G Meloni,G Saglio,F Salvatore,B Rotoli

View Articletitled, Neutrophilic-chronic myeloid leukemia: a distinct disease with a specific molecular marker (BCR/ABL with C3/A2 junction) [see comments]

P-selectin glycoprotein ligand-1 (PSGL-1) is a ligand for L-selectin in neutrophil aggregation

DA Guyer,KL Moore,EB Lynam,CM Schammel,S Rogelj,RP McEver,LA Sklar

View Articletitled, P-selectin glycoprotein ligand-1 (PSGL-1) is a ligand for L-selectin in neutrophil aggregation

A variant CD30 protein lacking extracellular and transmembrane domains is induced in HL-60 by tetradecanoylphorbol acetate and is expressed in alveolar macrophages

R Horie,K Ito,M Tatewaki,M Nagai,S Aizawa,M Higashihara,T Ishida,J Inoue,H Takizawa,T Watanabe

View Articletitled, A variant CD30 protein lacking extracellular and transmembrane domains is induced in HL-60 by tetradecanoylphorbol acetate and is expressed in alveolar macrophages

Dominant type 1 von Willebrand disease caused by mutated cysteine residues in the D3 domain of von Willebrand factor

JC Eikenboom,T Matsushita,PH Reitsma,EA Tuley,G Castaman,E Briet,JE Sadler

View Articletitled, Dominant type 1 von Willebrand disease caused by mutated cysteine residues in the D3 domain of von Willebrand factor

Granulocyte colony-stimulating factor activation of Stat3 alpha and Stat3 beta in immature normal and leukemic human myeloid cells

A Chakraborty,SM White,TS Schaefer,ED Ball,KF Dyer,DJ Tweardy

View Articletitled, Granulocyte colony-stimulating factor activation of Stat3 alpha and Stat3 beta in immature normal and leukemic human myeloid cells

Targeted T-cell therapy for human leukemia: cytotoxic T lymphocytes specific for a peptide derived from proteinase 3 preferentially lyse human myeloid leukemia cells

J Molldrem,S Dermime,K Parker,YZ Jiang,D Mavroudis,N Hensel,P Fukushima,AJ Barrett

View Articletitled, Targeted T-cell therapy for human leukemia: cytotoxic T lymphocytes specific for a peptide derived from proteinase 3 preferentially lyse human myeloid leukemia cells

Hematopoiesis in mice lacking the entire granulocyte-macrophage colony- stimulating factor/interleukin-3/interleukin-5 functions

R Nishinakamura,A Miyajima,PJ Mee,VL Tybulewicz,R Murray

View Articletitled, Hematopoiesis in mice lacking the entire granulocyte-macrophage colony- stimulating factor/interleukin-3/interleukin-5 functions

Effects of recombinant soluble type I interleukin-1 receptor on human inflammatory responses to endotoxin

HL 2nd Preas,D Reda,M Tropea,RW Vandivier,SM Banks,JM Agosti,AF Suffredini

View Articletitled, Effects of recombinant soluble type I interleukin-1 receptor on human inflammatory responses to endotoxin

Topotecan, a topoisomerase I inhibitor, is active in the treatment of myelodysplastic syndrome and chronic myelomonocytic leukemia

M Beran,H Kantarjian,S O'Brien,C Koller,M al-Bitar,S Arbuck,S Pierce,M Moore,JL Abbruzzese,M Andreeff,M Keating,E Estey

View Articletitled, Topotecan, a topoisomerase I inhibitor, is active in the treatment of myelodysplastic syndrome and chronic myelomonocytic leukemia

A randomized trial of hydroxyurea versus VP16 in adult chronic myelomonocytic leukemia. Groupe Francais des Myelodysplasies and European CMML Group

E Wattel,A Guerci,B Hecquet,T Economopoulos,A Copplestone,B Mahe,ME Couteaux,L Resegotti,V Voglova,C Foussard,B Pegourie,JL Michaux,E Deconinck,AM Stoppa,G Mufti,D Oscier,P Fenaux

View Articletitled, A randomized trial of hydroxyurea versus VP16 in adult chronic myelomonocytic leukemia. Groupe Francais des Myelodysplasies and European CMML Group

Regulation of mouse mast cell protease 6 gene expression by transcription factor encoded by the mi locus

E Morii,T Tsujimura,T Jippo,K Hashimoto,K Takebayashi,K Tsujino,S Nomura,M Yamamoto,Y Kitamura

View Articletitled, Regulation of mouse mast cell protease 6 gene expression by transcription factor encoded by the mi locus

Granulocyte colony-stimulating factor mobilizes into peripheral blood the complete clonal repertoire of hematopoietic precursors residing in the bone marrow of mice

F Varas,A Bernad,JA Bueren

View Articletitled, Granulocyte colony-stimulating factor mobilizes into peripheral blood the complete clonal repertoire of hematopoietic precursors residing in the bone marrow of mice

Estimation of the number of hematopoietic precursor cells during fetal mouse development by covariance analysis

CN Berger,KS Sturm

View Articletitled, Estimation of the number of hematopoietic precursor cells during fetal mouse development by covariance analysis

Direct growth suppression of myeloid bone marrow progenitor cells but not cord blood progenitors by human cytomegalovirus in vitro

M Holberg-Petersen,H Rollag,S Beck,I Overli,G Tjonnfjord,TG Abrahamsen,M Degre,K Hestdal

View Articletitled, Direct growth suppression of myeloid bone marrow progenitor cells but not cord blood progenitors by human cytomegalovirus in vitro

E3, a hematopoietic-specific transcript directly regulated by the retinoic acid receptor alpha

LM Scott,L Mueller,SJ Collins

View Articletitled, E3, a hematopoietic-specific transcript directly regulated by the retinoic acid receptor alpha

Macrophage colony-stimulating factor induces substantial osteoclast generation and bone resorption in human bone marrow cultures

U Sarma,AM Flanagan

View Articletitled, Macrophage colony-stimulating factor induces substantial osteoclast generation and bone resorption in human bone marrow cultures

In vitro differentiation of CD34+ hematopoietic progenitor cells toward distinct dendritic cell subsets of the birbeck granule and MIIC- positive Langerhans cell and the interdigitating dendritic cell type

B Herbst,G Kohler,A Mackensen,H Veelken,P Kulmburg,FM Rosenthal,HE Schaefer,R Mertelsmann,P Fisch,A Lindemann

View Articletitled, In vitro differentiation of CD34+ hematopoietic progenitor cells toward distinct dendritic cell subsets of the birbeck granule and MIIC- positive Langerhans cell and the interdigitating dendritic cell type

Interleukin-10 increases Bcl-2 expression and survival in primary human CD34+ hematopoietic progenitor cells

RM Weber-Nordt,R Henschler,E Schott,J Wehinger,D Behringer,R Mertelsmann,J Finke

View Articletitled, Interleukin-10 increases Bcl-2 expression and survival in primary human CD34+ hematopoietic progenitor cells

Type 2M:Milwaukee-1 von Willebrand disease: an in-frame deletion in the Cys509-Cys695 loop of the von Willebrand factor A1 domain causes deficient binding of von Willebrand factor to platelets

DJ Mancuso,PA Kroner,PA Christopherson,EA Vokac,JC Gill,RR Montgomery

View Articletitled, Type 2M:Milwaukee-1 von Willebrand disease: an in-frame deletion in the Cys509-Cys695 loop of the von Willebrand factor A1 domain causes deficient binding of von Willebrand factor to platelets

Fibulin-1 mediates platelet adhesion via a bridge of fibrinogen

S Godyna,M Diaz-Ricart,WS Argraves

View Articletitled, Fibulin-1 mediates platelet adhesion via a bridge of fibrinogen

Constitutive expression of Mpl ligand transcripts during thrombocytopenia or thrombocytosis

K Cohen-Solal,JL Villeval,M Titeux,S Lok,W Vainchenker,F Wendling

View Articletitled, Constitutive expression of Mpl ligand transcripts during thrombocytopenia or thrombocytosis

Biosynthesis of prothrombin: intracellular localization of the vitamin K-dependent carboxylase and the sites of gamma-carboxylation

JA Bristol,JV Ratcliffe,DA Roth,MA Jacobs,BC Furie,B Furie

View Articletitled, Biosynthesis of prothrombin: intracellular localization of the vitamin K-dependent carboxylase and the sites of gamma-carboxylation

Affinity modulation of the platelet integrin alpha IIb beta 3 by alpha- chymotrypsin: a possible role for Na+/Ca2+ exchanger

M Shiraga,Y Tomiyama,S Honda,H Kashiwagi,S Kosugi,M Handa,Y Ikeda,Y Kanakura,Y Kurata,Y Matsuzawa

View Articletitled, Affinity modulation of the platelet integrin alpha IIb beta 3 by alpha- chymotrypsin: a possible role for Na+/Ca2+ exchanger

Recombinant human factor IX: replacement therapy, prophylaxis, and pharmacokinetics in canine hemophilia B

KM Brinkhous,JL Sigman,MS Read,PF Stewart,KP McCarthy,GA Timony,SD Leppanen,BJ Rup,JC Jr Keith,PD Garzone,RG Schaub

View Articletitled, Recombinant human factor IX: replacement therapy, prophylaxis, and pharmacokinetics in canine hemophilia B

Genetic analysis and functional characterization of prothrombins Corpus Christi (Arg382-Cys), Dhahran (Arg271-His), and hypoprothrombinemia

AS O'Marcaigh,WL Nichols,NL Hassinger,JD Mullins,AA Mallouh,GS Gilchrist,WG Owen

View Articletitled, Genetic analysis and functional characterization of prothrombins Corpus Christi (Arg382-Cys), Dhahran (Arg271-His), and hypoprothrombinemia

Alloantigen presenting function of normal human CD34+ hematopoietic cells

D Rondelli,RG Andrews,JA Hansen,R Ryncarz,MA Faerber,C Anasetti

View Articletitled, Alloantigen presenting function of normal human CD34+ hematopoietic cells

Markedly disturbed glutathione redox status in CD45RA+CD4+ lymphocytes in human immunodeficiency virus type 1 infection is associated with selective depletion of this lymphocyte subset

P Aukrust,AM Svardal,F Muller,B Lunden,I Nordoy,SS Froland

View Articletitled, Markedly disturbed glutathione redox status in CD45RA+CD4+ lymphocytes in human immunodeficiency virus type 1 infection is associated with selective depletion of this lymphocyte subset

Inhibition of proliferation and induction of apoptosis in juvenile myelomonocytic leukemic cells by the granulocyte-macrophage colony- stimulating factor analogue E21R

PO Iversen,RL Rodwell,L Pitcher,KM Taylor,AF Lopez

View Articletitled, Inhibition of proliferation and induction of apoptosis in juvenile myelomonocytic leukemic cells by the granulocyte-macrophage colony- stimulating factor analogue E21R

Indication of an involvement of interleukin-1 beta converting enzyme- like protease in intramedullary apoptotic cell death in the bone marrow of patients with myelodysplastic syndromes

SD Mundle,P Venugopal,JD Cartlidge,DV Pandav,L Broady-Robinson,S Gezer,EL Robin,SR Rifkin,M Klein,DE Alston,BM Hernandez,D Rosi,S Alvi,VT Shetty,SA Gregory,A Raza

View Articletitled, Indication of an involvement of interleukin-1 beta converting enzyme- like protease in intramedullary apoptotic cell death in the bone marrow of patients with myelodysplastic syndromes

Establishment and characterization of a primary effusion (body cavity- based) lymphoma cell line (BC-3) harboring kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in the absence of Epstein-Barr virus

L Arvanitakis,EA Mesri,RG Nador,JW Said,AS Asch,DM Knowles,E Cesarman

View Articletitled, Establishment and characterization of a primary effusion (body cavity- based) lymphoma cell line (BC-3) harboring kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in the absence of Epstein-Barr virus

Identification of human juvenile chronic myelogenous leukemia stem cells capable of initiating the disease in primary and secondary SCID mice

T Lapidot,T Grunberger,J Vormoor,Z Estrov,O Kollet,N Bunin,R Zaizov,DE Williams,MH Freedman

View Articletitled, Identification of human juvenile chronic myelogenous leukemia stem cells capable of initiating the disease in primary and secondary SCID mice

Polymerase chain reaction-based diagnosis of del (5q) in acute myeloid leukemia and myelodysplastic syndrome identifies a minimal deletion interval

SK Horrigan,CA Westbrook,AH Kim,M Banerjee,W Stock,RA Larson

View Articletitled, Polymerase chain reaction-based diagnosis of del (5q) in acute myeloid leukemia and myelodysplastic syndrome identifies a minimal deletion interval

Alterations in expression, binding to ligand and DNA, and transcriptional activity of rearranged and wild-type retinoid receptors in retinoid-resistant acute promyelocytic leukemia cell lines

A Rosenauer,JV Raelson,C Nervi,P Eydoux,A DeBlasio,WH Jr Miller

View Articletitled, Alterations in expression, binding to ligand and DNA, and transcriptional activity of rearranged and wild-type retinoid receptors in retinoid-resistant acute promyelocytic leukemia cell lines

Autocrine loop through cholecystokinin-B/gastrin receptors involved in growth of human leukemia cells

N Iwata,T Murayama,Y Matsumori,M Ito,A Nagata,T Taniguchi,K Chihara,Y Matsuo,J Minowada,T Matsui

View Articletitled, Autocrine loop through cholecystokinin-B/gastrin receptors involved in growth of human leukemia cells

Interstitial deletion constitutes the major mechanism for loss of heterozygosity on chromosome 20q in polycythemia vera

FA Asimakopoulos,JG Gilbert,MA Aldred,TC Pearson,AR Green

View Articletitled, Interstitial deletion constitutes the major mechanism for loss of heterozygosity on chromosome 20q in polycythemia vera

Activating mutations of N- and K-ras in multiple myeloma show different clinical associations: analysis of the Eastern Cooperative Oncology Group Phase III Trial

P Liu,T Leong,L Quam,D Billadeau,NE Kay,P Greipp,RA Kyle,MM Oken,B Van Ness

View Articletitled, Activating mutations of N- and K-ras in multiple myeloma show different clinical associations: analysis of the Eastern Cooperative Oncology Group Phase III Trial

Ex vivo expansion of CD34+ peripheral blood progenitor cells: implications for the expansion of contaminating epithelial tumor cells

W Vogel,D Behringer,S Scheding,L Kanz,W Brugger

View Articletitled, Ex vivo expansion of CD34+ peripheral blood progenitor cells: implications for the expansion of contaminating epithelial tumor cells

Genomic structure, chromosomal localization, start of transcription, and tissue expression of the human p40-phox, a new component of the nicotinamide adenine dinucleotide phosphate-oxidase complex

S Zhan,N Vazquez,S Zhan,FB Wientjes,ML Budarf,E Schrock,T Ried,ED Green,SJ Chanock

View Articletitled, Genomic structure, chromosomal localization, start of transcription, and tissue expression of the human p40-phox, a new component of the nicotinamide adenine dinucleotide phosphate-oxidase complex

Targeted disruption of guanosine diphosphate-dissociation inhibitor for Rho-related proteins, GDID4: normal hematopoietic differentiation but subtle defect in superoxide production by macrophages derived from in vitro embryonal stem cell differentiation

JC Guillemot,BA Kruskal,CN Adra,S Zhu,JL Ko,P Burch,K Nocka,K Seetoo,E Simons,B Lim

View Articletitled, Targeted disruption of guanosine diphosphate-dissociation inhibitor for Rho-related proteins, GDID4: normal hematopoietic differentiation but subtle defect in superoxide production by macrophages derived from in vitro embryonal stem cell differentiation

Molecular genetic analysis of variant phenotypes of the ABO blood group system

K Ogasawara,R Yabe,M Uchikawa,N Saitou,M Bannai,K Nakata,M Takenaka,K Fujisawa,Y Ishikawa,T Juji,K Tokunaga

View Articletitled, Molecular genetic analysis of variant phenotypes of the ABO blood group system

Modulation of erythrocyte potassium chloride cotransport, potassium content, and density by dietary magnesium intake in transgenic SAD mouse

L De Franceschi,Y Beuzard,H Jouault,C Brugnara

View Articletitled, Modulation of erythrocyte potassium chloride cotransport, potassium content, and density by dietary magnesium intake in transgenic SAD mouse

Increased rotational mobility and extractability of band 3 from protein 4.2-deficient erythrocyte membranes: evidence of a role for protein 4.2 in strengthening the band 3-cytoskeleton linkage

AC Rybicki,RS Schwartz,EJ Hustedt,CE Cobb

View Articletitled, Increased rotational mobility and extractability of band 3 from protein 4.2-deficient erythrocyte membranes: evidence of a role for protein 4.2 in strengthening the band 3-cytoskeleton linkage

Receptor specificity of clinical Plasmodium falciparum isolates: nonadherence to cell-bound E-selectin and vascular cell adhesion molecule-1

R Udomsangpetch,BJ Taylor,S Looareesuwan,NJ White,JF Elliott,M Ho

View Articletitled, Receptor specificity of clinical Plasmodium falciparum isolates: nonadherence to cell-bound E-selectin and vascular cell adhesion molecule-1

Interaction of hemoglobin E and pyrimidine 5' nucleotidase deficiency

DC Rees,J Duley,HA Simmonds,B Wonke,SL Thein,JB Clegg,DJ Weatherall

View Articletitled, Interaction of hemoglobin E and pyrimidine 5' nucleotidase deficiency

Quantification of hepatitis C virus-infected peripheral blood mononuclear cells by in situ reverse transcriptase-polymerase chain reaction

L Muratori,D Gibellini,M Lenzi,M Cataleta,P Muratori,MC Morelli,FB Bianchi

View Articletitled, Quantification of hepatitis C virus-infected peripheral blood mononuclear cells by in situ reverse transcriptase-polymerase chain reaction

Improved immune reconstitution after allotransplantation of peripheral blood stem cells instead of bone marrow

HD Ottinger,DW Beelen,B Scheulen,UW Schaefer,H Grosse-Wilde

View Articletitled, Improved immune reconstitution after allotransplantation of peripheral blood stem cells instead of bone marrow

High-dose therapy and autologous bone marrow transplantation in patients with follicular lymphoma during first remission

AS Freedman,JG Gribben,D Neuberg,P Mauch,RJ Soiffer,KC Anderson,L Pandite,MJ Robertson,M Kroon,J Ritz,LM Nadler

View Articletitled, High-dose therapy and autologous bone marrow transplantation in patients with follicular lymphoma during first remission

Allogeneic marrow transplantation for multiple myeloma: an analysis of risk factors on outcome

WI Bensinger,CD Buckner,C Anasetti,R Clift,R Storb,T Barnett,T Chauncey,H Shulman,FR Appelbaum

View Articletitled, Allogeneic marrow transplantation for multiple myeloma: an analysis of risk factors on outcome

Allogeneic peripheral blood stem cell transplantation in patients with advanced hematologic malignancies: a retrospective comparison with marrow transplantation

WI Bensinger,R Clift,P Martin,FR Appelbaum,T Demirer,T Gooley,K Lilleby,S Rowley,J Sanders,R Storb,CD Buckner

View Articletitled, Allogeneic peripheral blood stem cell transplantation in patients with advanced hematologic malignancies: a retrospective comparison with marrow transplantation

Dose-intensive melphalan with blood stem cell support for the treatment of AL amyloidosis: one-year follow-up in five patients

RL Comenzo,E Vosburgh,RW Simms,P Bergethon,D Sarnacki,K Finn,S Dubrey,DV Faller,DG Wright,RH Falk,M Skinner

View Articletitled, Dose-intensive melphalan with blood stem cell support for the treatment of AL amyloidosis: one-year follow-up in five patients

PHOTOGRAPHS

Photograph

A. M. Dvorak

View Articletitled, Photograph

LETTER

Hydroxyurea therapy in highly unstable hemoglobin carriers [letter]

C Rose,F Bauters,F Galacteros

View Articletitled, Hydroxyurea therapy in highly unstable hemoglobin carriers [letter]

Molecular investigation of secondary chronic myeloid leukemia [letter]

RC Aguiar,H Sill,A Hochhaus,JM Goldman,NC Cross

View Articletitled, Molecular investigation of secondary chronic myeloid leukemia [letter]

ERRATUM

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