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Journal Articles

The Transmembrane Protein CD37 Is Not a Promising Therapeutic Target in Acute Myeloid Leukaemia

Tara Helen Dowling Dowling Steinsland, MSc, Stein-Erik Gullaksen, MS, PhD, Geir Bredholt, PhD, Calum Leitch, PhD, Mireia Mayoral Safont, BS, Øystein Bruserud, MD PhD, Mihaela Popa, Astri Maaland, Helen Heyerdahl, PhD, Jostein Dahle, PhD, Bjorn T. Gjertsen, MD PhD, Emmet Mccormack, BSc, PhD

Blood (2020) 136 (Supplement 1): 26.

https://doi.org/10.1182/blood-2020-142899

Published: 2020

Journal Articles

Development of Novel Highly Specific FLT3 Targeted Inhibitors for Combination or Sequential Therapy of Acute Myeloid Leukemia

Misbah Sabir, MSc, Monica Hellesoy, PhD, Jarno Kivioja, MSc, Caroline Engen, MD, Claire Amiable, Mihaela Popa, Remi Guillon, Øystein Bruserud, MD PhD, Caroline A Heckman, PhD, Emmet McCormack, BSc, PhD, Dominique Surleraux, Bjørn Tore Gjertsen

Blood (2017) 130 (Supplement 1): 3349.

https://doi.org/10.1182/blood.V130.Suppl_1.3349.3349

Published: 2017

Journal Articles

Single Cell Signaling Pharmacodynamics in a Phase 1b Trial of the Axl Inhibitor BGB324 in Acute Myeloid Leukemia

Monica Hellesøy, PhD, Stein-Erik Gullaksen, Benedicte Sjo Tislevoll, Oda Helen Eck Fagerholt, Hakon Reikvam, MD PhD, Sonja Loges, MD PhD, Jorge Cortes, MD, Michael Heuser, MD, Jörg Chromik, Jørn Skavland, PhD, André Sulen, Øystein Bruserud, MD PhD, Jim Lorens, PhD, Gro Gausdal, PhD, David Micklem, Bjorn T. Gjertsen, MD PhD

Blood (2016) 128 (22): 3995.

https://doi.org/10.1182/blood.V128.22.3995.3995

Published: 2016

Journal Articles

Single Cell-Level Signaling Profiling of Acute Myeloid Leukemia Following Treatment with Axl Kinase Inhibitor BGB324

Monica Hellesøy, PhD, Katarzyna Wnuk-Lipinska, PhD, Anna Boniecka, MSc, Eline Milde Nævdal, Hakon Reikvam, MDPhD, Sonja Loges, MDPhD, Jorge E. Cortes, MD, Jørn Skavland, PhD, Øystein Bruserud, MDPhD, Jim Lorens, PhD, David Micklem, PhD, Gro Gausdal, PhD, Bjorn T. Gjertsen, MD PhD

Blood (2015) 126 (23): 4931.

https://doi.org/10.1182/blood.V126.23.4931.4931

Published: 2015

Journal Articles

Survival Stratification In Acute Myeloid Leukemia By Single Cell Signal Profiling

Jørn Skavland, PhD, Håkon Reikvam, MD/PhD, Øystein Bruserud, MD, PhD, Bjorn T. Gjertsen, MD PhD

Blood (2013) 122 (21): 2625.

https://doi.org/10.1182/blood.V122.21.2625.2625

Published: 2013

Journal Articles

Myeloid Derived Suppressor Cell Expansion Correlates With Increased regulatory T Cells In Myelodysplastic Syndrome

Astrid Olsnes Kittang, MD, PhD, Shahram Kordasti, MD, PhD, Kristoffer Evebø Sand, MD, Pilar Perezabellan, Thomas Seidl, Kristin Paulsen Rye, Karen Marie Hagen, Geir Hallan, MD, PhD, Austin G Kulasekararaj, MD, PhD, Øystein Bruserud, MD, PhD, Ghulam J. Mufti, MD, PhD

Blood (2013) 122 (21): 2766.

https://doi.org/10.1182/blood.V122.21.2766.2766

Published: 2013

Journal Articles

Elacytarabine Is More Effective Preclinically Than Cytarabine In Combination With Daunorubicin In Primary Patient Xenografts Of AML

Tereza Osdal, MSc, Mihaela Lucia Popa, VMD, Lene Mari Vikebø, Andre Sulen, MSc, Siv Lise Bendringaas, Marit Liland Sandvold, PhD, Birgitte Booij, PhD, Øystein Bruserud, MD, PhD, Bjørn Tore Gjertsen, MD, PhD, Emmet McCormack, PhD

Blood (2013) 122 (21): 3958.

https://doi.org/10.1182/blood.V122.21.3958.3958

Published: 2013

Journal Articles

Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia

Emmet McCormack, Maja Mujić, Tereza Osdal, Øystein Bruserud, Bjørn Tore Gjertsen

Blood (2013) 121 (7): e34–e42.

https://doi.org/10.1182/blood-2012-05-429555

Published: 2013

Includes: Supplemental data

Journal Articles

The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling

Emma Lång, Amra Grudic, Serhiy Pankiv, Øystein Bruserud, Anne Simonsen, Rolf Bjerkvig, Magnar Bjørås, Stig Ove Bøe

Blood (2012) 120 (4): 847–857.

https://doi.org/10.1182/blood-2011-10-388496

Published: 2012

Includes: Multimedia, Supplemental data

Journal Articles

Serum Heat Shock Protein Levels and Cytokine Profiles Are Altered In AML Patients Before Treatment and Following Disease Stabilizing Therapy,

Hanne Fredly, MD, Håkon Reikvam, MD, Bjorn T. Gjertsen, MD, PhD, Øystein Bruserud, MD, PhD

Blood (2011) 118 (21): 3599.

https://doi.org/10.1182/blood.V118.21.3599.3599

Published: 2011

Journal Articles

Connexin Expression by Human Primary AML Cells

Brynjar Foss, MSc, PhD, Lars Rune Sæterdal, Anita Ryningen, Anne M. Øyan, Øystein Bruserud

Blood (2010) 116 (21): 2147.

https://doi.org/10.1182/blood.V116.21.2147.2147

Published: 2010

Journal Articles

Circulating T Cells Derived From Patients with Low Risk Myelodysplastic Syndromes Show Altered Chemokine Receptor Expression

Kristoffer E Sand, Astrid Olsnes Kittang, Øystein Bruserud

Blood (2010) 116 (21): 4018.

https://doi.org/10.1182/blood.V116.21.4018.4018

Published: 2010

Journal Articles

Antivascular combo therapy: up-and-coming

Øystein Bruserud, Kimberley Hatfield

Blood (2010) 116 (9): 1389–1390.

https://doi.org/10.1182/blood-2010-05-286203

Published: 2010

Journal Articles

Identification of Molecular Targets of AML by Phosphoproteomic Screening of Valproic Acid Treated BNML and C. Elegans RNAi Validation.

Rakel Brendsdal Forthun, Emmet McCormack, Tanima Sengupta, Siv Lise Bedringaas, Øystein Bruserud, Gry Sjøholt, Hilde Nilsen, Bjorn Gjertsen

Blood (2009) 114 (22): 4151.

https://doi.org/10.1182/blood.V114.22.4151.4151

Published: 2009

Journal Articles

Evaluation of Combinational Therapy of MDM2-Antagonist Nutlin-3 and HDAC-Inhibitor Valproic Acid in Acute Myeloid Leukemia in Vitro and in Vivo

Emmet McCormack, Ingvild Haaland, Gurid Venås, Rakel Brendsdal Forthun, Øystein Bruserud, Bjørn Tore Gjertsen

Blood (2008) 112 (11): 2981.

https://doi.org/10.1182/blood.V112.11.2981.2981

Published: 2008

Journal Articles

Abolition of stress-induced protein synthesis sensitizes leukemia cells to anthracycline-induced death

Gro Gausdal, Bjørn Tore Gjertsen, Emmet McCormack, Petra Van Damme, Randi Hovland, Camilla Krakstad, Øystein Bruserud, Kris Gevaert, Joël Vandekerckhove, Stein Ove Døskeland

Blood (2008) 111 (5): 2866–2877.

https://doi.org/10.1182/blood-2007-07-103242

Published: 2008

Includes: Supplemental data

Journal Articles

Flt3 Mutations in Proximity to an Ubiquitin Dependent Endocytosis Motif Suspend Its Hdm2 Modulation.

Line Wergeland, PhD, Eystein Oveland, MSc, Gry Sjoholt, PhD, Siv Lise Bedringaas, MSc, Randi T. Hovland, PhD, Oystein Bruserud, MD, PhD, Bjorn T. Gjertsen, MD, PhD

Blood (2007) 110 (11): 4320.

https://doi.org/10.1182/blood.V110.11.4320.4320

Published: 2007

Journal Articles

Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53

Jonathan M. Irish, Nina Ånensen, Randi Hovland, Jørn Skavland, Anne-Lise Børresen-Dale, Øystein Bruserud, Garry P. Nolan, Bjørn T. Gjertsen

Blood (2006) 109 (6): 2589–2596.

https://doi.org/10.1182/blood-2006-02-004234

Published: 2006

Includes: Supplemental data

Journal Articles

A Phase II Trial of Pegylated Interferon α-2b in Polycythemia Vera and Essential Thrombocythemia. Clinical Responses, Effects on PRV-1 Expression and Impact on Quality of Life.

Jan Samuelsson, MD, PhD, Hans Hasselbalch, Oystein Bruserud, Heike Pahl, Mats Merup, Olle Linder, Yvonne Brandberg, Poul Gram-Hansen, Magnus Bjorkholm, Waleed Ghanima, Claes Malm, Berit Markevarn, Torben Mourits-Andersen, Peter Johansson, Lars Nilsson, Gunnar Birgegard

Blood (2004) 104 (11): 1518.

https://doi.org/10.1182/blood.V104.11.1518.1518

Published: 2004

NARROW

The Transmembrane Protein CD37 Is Not a Promising Therapeutic Target in Acute Myeloid Leukaemia

Development of Novel Highly Specific FLT3 Targeted Inhibitors for Combination or Sequential Therapy of Acute Myeloid Leukemia

Single Cell Signaling Pharmacodynamics in a Phase 1b Trial of the Axl Inhibitor BGB324 in Acute Myeloid Leukemia

Single Cell-Level Signaling Profiling of Acute Myeloid Leukemia Following Treatment with Axl Kinase Inhibitor BGB324

Survival Stratification In Acute Myeloid Leukemia By Single Cell Signal Profiling

Myeloid Derived Suppressor Cell Expansion Correlates With Increased regulatory T Cells In Myelodysplastic Syndrome

Elacytarabine Is More Effective Preclinically Than Cytarabine In Combination With Daunorubicin In Primary Patient Xenografts Of AML

Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia

The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling

Serum Heat Shock Protein Levels and Cytokine Profiles Are Altered In AML Patients Before Treatment and Following Disease Stabilizing Therapy,

Connexin Expression by Human Primary AML Cells

Circulating T Cells Derived From Patients with Low Risk Myelodysplastic Syndromes Show Altered Chemokine Receptor Expression

Antivascular combo therapy: up-and-coming

Identification of Molecular Targets of AML by Phosphoproteomic Screening of Valproic Acid Treated BNML and C. Elegans RNAi Validation.

Evaluation of Combinational Therapy of MDM2-Antagonist Nutlin-3 and HDAC-Inhibitor Valproic Acid in Acute Myeloid Leukemia in Vitro and in Vivo

Abolition of stress-induced protein synthesis sensitizes leukemia cells to anthracycline-induced death

Flt3 Mutations in Proximity to an Ubiquitin Dependent Endocytosis Motif Suspend Its Hdm2 Modulation.

Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53

A Phase II Trial of Pegylated Interferon α-2b in Polycythemia Vera and Essential Thrombocythemia. Clinical Responses, Effects on PRV-1 Expression and Impact on Quality of Life.

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American Society of Hematology

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American Society of Hematology

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