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Journal Articles

The NAD + Metabolic Dependency Restriction Overcomes Drug-Resistance Phenotype of Multiple Myeloma CELLS

Debora Soncini, Pamela Becherini, Silvia Ravera, Claudia Martinuzzi, Alessio Nencioni, Santina Bruzzone, Francesco Piacente, Giulia Giorgetti, Francesco Ladisa, Michel A. Duchosal, Aimable Nahimana, Roberto M. Lemoli, Michele Cea
Journal: Blood
Blood (2023) 142 (Supplement 1): 6609.
https://doi.org/10.1182/blood-2023-189720
Published: 2023
Journal Articles

Higher CD56 Expression on Multiple Myeloma Cells Increases CD38 Expression, Reduces Intracellular NAD+ Levels, and Enhances the Efficacy of Daratumumab-Based Treatment Strategies

Giulia Giorgetti, Pamela Becherini, Elena Maroto-Martin, Daniela Fenoglio, Debora Soncini, Claudia Martinuzzi, Santina Bruzzone, Andrea Benzi, Aimable Nahimana, Chiara Rosa Maria Uras, Anaïs Schavgoulidze, Jessica Ng Fong, Roberto M. Lemoli, Nikhil C Munshi, Mariateresa Fulciniti, Michele Cea
Journal: Blood
Blood (2023) 142 (Supplement 1): 1951.
https://doi.org/10.1182/blood-2023-189439
Published: 2023
Journal Articles

The NAD+ Salvage Pathway Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance and Asymmetric Division

Nicola Vannini, PhD, Vasco Campos, MSc, Mukul Girotra, PhD, Shanti Rojas-Sutterlin, PhD, Josefine Tratwal, Simone Ragusa, PhD, Evangelos Stefanidis, Dongryeol Ryu, PhD, Pernille Y. Rainer, Gennady Nikitin, Sonja Giger, Yang Li Terytty, Aikateirini Semilietof, Aurelien L. Oggier, Yannick Yersin, Loïc Tauzin, Eija Pirinen, PhD, Wan-Chen Cheng, Joanna Ratajczak, PhD, Carles Canto, PhD, Martin Ehrbar, PhD, Federico Sizzano, PhD, Tatiana V. Petrova, PhD, Dominique Vanhecke, PhD, Aimable Nahimana, PhD, Michel A. Duchosal, MD, Ping-Chih Ho, PhD, Bart Deplancke, PhD, George Coukos, MD, PhD, Matthias P. Lutolf, PhD, Olaia Naveiras, MD, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 641.
https://doi.org/10.1182/blood-2018-99-117388
Published: 2018
Journal Articles

Response: NAD targeting efficiently kills hematologic cancer cells

Aimable Nahimana, Dominique Aubry, Steven Butcher, Michel A. Duchosal
Journal: Blood
Blood (2009) 113 (23): 6037–6038.
https://doi.org/10.1182/blood-2009-04-211243
Published: 2009
Journal Articles

The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies

Aimable Nahimana, Antoine Attinger, Dominique Aubry, Peter Greaney, Christopher Ireson, Annemette V. Thougaard, Jette Tjørnelund, Keith M. Dawson, Marc Dupuis, Michel A. Duchosal
Journal: Blood
Blood (2009) 113 (14): 3276–3286.
https://doi.org/10.1182/blood-2008-08-173369
Published: 2009
Includes: Supplemental data