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Akihiro Hashimoto
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Journal Articles

TAS4464, a Novel, Highly Potent NEDD8-Activating Enzyme Inhibitor Shows Antitumor Activity in Ibrutinib-Insensitive Mantle Cell Lymphoma Via Inactivation of the NF-κB Pathway

Hiromi Muraoka, MS, Chihoko Yoshimura, PhD, Shingo Tsuji, MS, Akihiro Hashimoto, Fumio Nakagawa, Takashi Mizutani, PhD, Shuichi Ohkubo, PhD, Kenichi Matsuo, PhD, Teruhiro Utsugi, PhD, Yoshikazu Iwasawa, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4103.
https://doi.org/10.1182/blood.V130.Suppl_1.4103.4103
Published: 2017
Journal Articles

Novel Small-Molecule Inhibitors Targeting Complement Factor D for Therapy of Paroxysmal Nocturnal Hemoglobinuria

B. Paul Morgan, PhD, Jane Thanassi, Steven Podos, PhD, Avinash Phadke, PhD, Venkat Gadhachanda, PhD, Godwin Pais, PhD, Akihiro Hashimoto, PhD, Qiuping Wang, PhD, Dawei Chen, PhD, Xiangzhu Wang, PhD, Atul Agarwal, PhD, Milind Deshpande, PhD, Yongqing Huang, PhD, Jason Wiles, PhD, Mingjun Huang, PhD
Journal: Blood
Blood (2014) 124 (21): 4817.
https://doi.org/10.1182/blood.V124.21.4817.4817
Published: 2014
Journal Articles

Preclinical Evaluation of Orally Bioavailable Small-Molecule Inhibitors of Complement Factor D As a Potential Treatment for Paroxysmal Nocturnal Hemoglobinuria

Jason Wiles, PhD, Steven Podos, PhD, Jane Thanassi, Avinash Phadke, PhD, Venkat Gadhachanda, PhD, Godwin Pais, PhD, Akihiro Hashimoto, PhD, Qiuping Wang, PhD, Dawei Chen, PhD, Xiangzhu Wang, PhD, Atul Agarwal, PhD, Jose Rivera, Michael Elliot, Christopher Marlor, Jay Zhang, Milind Deshpande, PhD, Mingjun Huang, PhD, Yongqing Huang, PhD
Journal: Blood
Blood (2014) 124 (21): 4819.
https://doi.org/10.1182/blood.V124.21.4819.4819
Published: 2014