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Journal Articles

Spatial transcriptomic analysis of chronic lymphocytic leukemia lymph nodes reveals tumor microenvironment evolution during disease progression

Maria Carmela Vegliante, Benedetta Apollonio, Antonella Bucci, Giulia Notarpietro, Susanna Anita Pappagallo, Paolo Mondelli, Rossana Daprile, Anna Scattone, Michela Frenquelli, Attilio Guarini, Giancarlo Castellano, Alessia Ciarrocchi, Benedetta Donati, Maurilio Ponzoni, Paolo Ghia, Carla Minoia

Blood (2025) 146 (Supplement 1): 3880.

https://doi.org/10.1182/blood-2025-3880

Published: 2025

Journal Articles

The chromatin remodeler hells regulates transcription-replication conflicts and genome integrity in ALK-negative anaplastic large cell lymphoma

Selene Mallia, Giulia Gambarelli, Veronica Manicardi, Benedetta Donati, Emanuele Vitale, Federica Torricelli, Elisa Salviato, Magda Zanelli, Noemi Puccio, Stefano Luminari, Francesco Merli, Antonino Neri, Alessia Ciarrocchi, Valentina Fragliasso

Blood (2025) 146 (Supplement 1): 1477.

https://doi.org/10.1182/blood-2025-1477

Published: 2025

Journal Articles

Targeting hells‑mediated chromatin accessibility to sensitize ALK‑negative anaplastic large cell lymphoma to JAK/STAT and DNA‑PK inhibition

Giulia Gambarelli, Selene Mallia, Benedetta Donati, Noemi Puccio, Magda Zanelli, Emanuele Vitale, Federica Torricelli, Veronica Manicardi, Elisa Salviato, Stefano Luminari, Francesco Merli, Antonino Neri, Alessia Ciarrocchi, Valentina Fragliasso

Blood (2025) 146 (Supplement 1): 1476.

https://doi.org/10.1182/blood-2025-1476

Published: 2025

Journal Articles

Morphology guided spatial transcriptomics to study topography of Hodgkin reed sternberg cells interaction with tumor microenvironment and its impact in defining risk of progression in classical Hodgkin lymphoma.

Benedetta Donati, Tanja Lazic, Riccardo Valli, Rexhep Durmo, Attilio Gennaro, Cristian Ascione, Pierluigi Di Chiaro, Alessia Ruffini, Manuel Gotti, Luca Arcaini, Erica Travaglino, Marco Paulli, Francesco Merli, Alessia Ciarrocchi, Stefano Luminari

Blood (2025) 146 (Supplement 1): 5315.

https://doi.org/10.1182/blood-2025-5315

Published: 2025

Journal Articles

Disruption of NEAT1-transcriptional network identifies targetable non-genetic dependencies in multiple myeloma

Noemi Puccio, Christian Boni, Federica Torricelli, Emanuele Vitale, Elisa Taiana, Domenica Ronchetti, Valentina Fragliasso, Selene Mallia, Giulia Gambarelli, Roberto Piva, Niccolo Bolli, Stefano Luminari, Alessia Ciarrocchi, Antonino Neri

Blood (2025) 146 (Supplement 1): 3945.

https://doi.org/10.1182/blood-2025-3945

Published: 2025

Journal Articles

Transcriptomic Profiling Reveals Key Biomarkers in Primary Refractory and Early Relapse Classical Hodgkin Lymphoma

Tanja Lazic, Benedetta Donati, Maria Elena Nizzoli, Alberto Bavieri, Rexhep Durmo, Riccardo Valli, Attilio Gennaro, Cristian Ascione, Alessia Ruffini, Stefano Pozzi, Annibale Versari, Francesco Merli, Stefano Luminari, Alessia Ciarrocchi

Blood (2024) 144 (Supplement 1): 6205.

https://doi.org/10.1182/blood-2024-207696

Published: 2024

Journal Articles

Hells (LSH) Controls Gene Expression in T-Cell Lymphomas By Regulating RNA Polymerase II with a Bimodal Function

Valentina Fragliasso, Veronica Manicardi, Annalisa Tameni, Selene Mallia, Benedetta Donati, Federica Torricelli, Emanuele Vitale, Magda Zanelli, Stefano Luminari, Stefano Ascani, Francesca Sanguedolce, Noemi Puccio, Antonino Neri, Alessia Ciarrocchi

Blood (2023) 142 (Supplement 1): 2778.

https://doi.org/10.1182/blood-2023-177555

Published: 2023

Journal Articles

Novel Combinatorial Therapeutic Options in NEAT1-Depleted Multiple Myeloma Cells By the Integration of in Vitro and in silico Drug Screening Approaches

Noemi Puccio, Elisa Taiana, Gloria Manzotti, Elisabetta Mereu, Domenica Ronchetti, Cecilia Bandini, Ilaria Craparotta, Laura Di Rito, Marco Bolis, Veronica Manicardi, Valentina Fragliasso, Nicola Amodio, Niccolò Bolli, Stefano Luminari, Alessia Ciarrocchi, Roberto Piva, Antonino Neri

Blood (2023) 142 (Supplement 1): 6612.

https://doi.org/10.1182/blood-2023-190131

Published: 2023

Journal Articles

Hells Promotes Transcription in Lymphoma By Resolving Topological Conflicts and By Preventing DNA Damage

Annalisa Tameni, Elisabetta Sauta, Federica Torricelli, Valentina Mularoni, Emanuele Vitale, Marco Tigano, Alessia Ciarrocchi, Valentina Fragliasso

Blood (2021) 138 (Supplement 1): 2204.

https://doi.org/10.1182/blood-2021-146170

Published: 2021

Journal Articles

The DNA Helicase Hells Is a New Unconventional Player in ALK - Anaplastic Large Cell Lymphoma Biology

Valentina Fragliasso, PhD, Annalisa Tameni, Akanksha Verma, Rohan Bareja, Tayla Heavican, Javeed Iqbal, PhD, Gloria Manzotti, PhD, Danilo Fiore, PhD, Valentina Mularoni, PhD, Wing C. Chan, MD, Francesco Merli, MD, Olivier Elemento, PhD, Alessia Ciarrocchi, PhD, Giorgio Inghirami, MD

Blood (2019) 134 (Supplement_1): 1477.

https://doi.org/10.1182/blood-2019-122701

Published: 2019

Journal Articles

Novel Long Non Coding RNA Blackmamba Is Associated to ALK - anaplastic Large Cell Lymphoma

Valentina Fragliasso, PhD, Akanksha Verma, Rohan Bareja, Tayla Heavican, Javeed Iqbal, PhD, Wing Chung Chan, MD, Francesco Merli, Alessia Ciarrocchi, PhD, Olivier Elemento, PhD, Giorgio Inghirami, MD

Blood (2016) 128 (22): 461.

https://doi.org/10.1182/blood.V128.22.461.461

Published: 2016

Journal Articles

Identification of Key Cellular Regulators That Interact with Id1 To Control Hematopoietic Stem Cell Behavior.

Vladimir Jankovic, MD, Alessia Ciarrocchi, PhD, Tony DeBlasio, Robert Benezra, PhD, Stephen D. Nimer, MD

Blood (2006) 108 (11): 1319.

https://doi.org/10.1182/blood.V108.11.1319.1319

Published: 2006

Journal Articles

Id1 Regulates the Choice of Hematopoietic Stem Cells to Self-Renew or Commit to Differentiation.

Vladimir Jankovic, MD, Alessia Ciarrocchi, PhD, Piernicola Boccuni, MD, Robert Benezra, PhD, Stephen D. Nimer, MD

Blood (2005) 106 (11): 270.

https://doi.org/10.1182/blood.V106.11.270.270

Published: 2005

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Spatial transcriptomic analysis of chronic lymphocytic leukemia lymph nodes reveals tumor microenvironment evolution during disease progression

The chromatin remodeler hells regulates transcription-replication conflicts and genome integrity in ALK-negative anaplastic large cell lymphoma

Targeting hells‑mediated chromatin accessibility to sensitize ALK‑negative anaplastic large cell lymphoma to JAK/STAT and DNA‑PK inhibition

Morphology guided spatial transcriptomics to study topography of Hodgkin reed sternberg cells interaction with tumor microenvironment and its impact in defining risk of progression in classical Hodgkin lymphoma.

Disruption of NEAT1-transcriptional network identifies targetable non-genetic dependencies in multiple myeloma

Transcriptomic Profiling Reveals Key Biomarkers in Primary Refractory and Early Relapse Classical Hodgkin Lymphoma

Hells (LSH) Controls Gene Expression in T-Cell Lymphomas By Regulating RNA Polymerase II with a Bimodal Function

Novel Combinatorial Therapeutic Options in NEAT1-Depleted Multiple Myeloma Cells By the Integration of in Vitro and in silico Drug Screening Approaches

Hells Promotes Transcription in Lymphoma By Resolving Topological Conflicts and By Preventing DNA Damage

The DNA Helicase Hells Is a New Unconventional Player in ALK - Anaplastic Large Cell Lymphoma Biology

Novel Long Non Coding RNA Blackmamba Is Associated to ALK - anaplastic Large Cell Lymphoma

Identification of Key Cellular Regulators That Interact with Id1 To Control Hematopoietic Stem Cell Behavior.

Id1 Regulates the Choice of Hematopoietic Stem Cells to Self-Renew or Commit to Differentiation.

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American Society of Hematology

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