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Journal Articles

Blockade of the Neonatal Fc Receptor (FcRn) Represents an Effective Mechanism for the Removal of Pathogenic Autoantibodies in Primary Immune Thrombocytopenia

Alison Eddleston, Kevin Greenslade, Omar Qureshi, Shauna West, Paul Atherfold, Ali Amirkhosravi, Hina Desai, Mildred Rivera-Amaya, Bryan Smith, Anthony Shock, PhD

Blood (2017) 130 (Supplement 1): 230.

https://doi.org/10.1182/blood.V130.Suppl_1.230.230

Published: 2017

Journal Articles

CD32a antibodies induce thrombocytopenia and type II hypersensitivity reactions in FCGR2A mice

Todd Meyer, Liza Robles-Carrillo, Monica Davila, Meghan Brodie, Hina Desai, Mildred Rivera-Amaya, John L. Francis, Ali Amirkhosravi

Blood (2015) 126 (19): 2230–2238.

https://doi.org/10.1182/blood-2015-04-638684

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

β 2 -Glycoprotein 1 Antibodies Directly Activate the Platelet IgG Receptor, FcγRIIa, and Cause Thrombosis in FCGR2A Transgenic but Not in Wild Type Mice

Ali Amirkhosravi, PhD, Todd V Meyer, PhD., Liza Robles-Carrillo, MS., Meghan Hatfield, M.S., Hina Desai, M.S., Mildred Amaya, M.S., Florian Langer, MD, Steven E. McKenzie, MD, PhD, John L Francis, PhD

Blood (2012) 120 (21): 106.

https://doi.org/10.1182/blood.V120.21.106.106

Published: 2012

Journal Articles

Differential Effects of Protein Disulfide Isomerase (PDI) Inhibitors On the Expression of Tissue Factor Procoagulant Activity (TF PCA) by AML Blasts

Cornelia Fischer, Brigitte Spath, Ali Amirkhosravi, PhD, Walter Fiedler, MD, Carsten Bokemeyer, Florian Langer, MD

Blood (2012) 120 (21): 1112.

https://doi.org/10.1182/blood.V120.21.1112.1112

Published: 2012

Journal Articles

Assessment of Protein C Anticoagulant Pathway by Thrombin Generation Assay in the Presence of Endothelial Cells

Enriqueta Coll, PhD, Liza Robles-Carrillo, MS., Eduardo Reyes, MS, John L Francis, PhD, Ali Amirkhosravi, PhD

Blood (2012) 120 (21): 3394.

https://doi.org/10.1182/blood.V120.21.3394.3394

Published: 2012

Journal Articles

Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice

Ana M. Gil-Bernabé, Špela Ferjančič, Monika Tlalka, Lei Zhao, Philip D. Allen, Jae Hong Im, Karla Watson, Sally A. Hill, Ali Amirkhosravi, John L. Francis, Jeffrey W. Pollard, Wolfram Ruf, Ruth J. Muschel

Blood (2012) 119 (13): 3164–3175.

https://doi.org/10.1182/blood-2011-08-376426

Published: 2012

Includes: Multimedia, Supplemental data

Journal Articles

Comparison of Platelet-Activating Potential of Bevacizumab+VEGF and Aflibercept+VEGF Complexes

Todd Meyer, PhD., Liza Robles-Carrillo, M.S., Hina Desai, M.S., Meghan Hatfield, M.S., Mildred Amaya, M.S., John Francis, PhD, Ali Amirkhosravi, PhD.

Blood (2010) 116 (21): 3200.

https://doi.org/10.1182/blood.V116.21.3200.3200

Published: 2010

Journal Articles

CDP7657, and Other Anti-CD40L Antibody Formats Lacking a Functional Fc Region, Do Not Cause Platelet Activation In Vitro

Ali Amirkhosravi, PhD., Todd Meyer, PhD., Olivier Harari, PhD., Linda Burkly, PhD., Lihe Su, PhD., Yen-Ming Hsu, PhD., Timothy Bourne, PhD., Ian Wakefield, PhD., Christopher Peters, PhD., Anthony Shock, PhD., John Francis, PhD

Blood (2010) 116 (21): 5128.

https://doi.org/10.1182/blood.V116.21.5128.5128

Published: 2010

Journal Articles

Role of Protein Disulfide Isomerase (PDI) In the Expression of Tissue Factor (TF) Procoagulant Activity on Apoptotic Myeloblasts

Brigitte Spath, Ali Amirkhosravi, PhD, Monica Davila, PhD, John L. Francis, PhD, Barbara Eifrig, MD, Carsten Bokemeyer, MD, Florian Langer, MD

Blood (2010) 116 (21): 152.

https://doi.org/10.1182/blood.V116.21.152.152

Published: 2010

Journal Articles

Mechanism of Thrombocytopenia Induced by Anti-CD40 Ligand Immune Complexes and the Prevalence of CD40 Ligand Autoantibodies in Patients with Thrombotic Autoimmune Disorders

Ali Amirkhosravi, Ph.D., Todd V Meyer, Ph.D., Liza Robles-Carillo, MS, Monica Davila, Ph.D., Florian Langer, MD, Hina Desai, MS, Patricia Weinstein, RN, Mildred Amaya, MS, Eduardo Reyes, MS, John L Francis, Ph.D.

Blood (2008) 112 (11): 2857.

https://doi.org/10.1182/blood.V112.11.2857.2857

Published: 2008

Journal Articles

Bevacizumab Immune Complexes Induce Thrombocytopenia and Thrombosis in Mice Transgenic for Human IgG Receptor FcYIIa

Ali Amirkhosravi, Ph.D., Todd V Meyer, Ph.D., Liza Robles-Carillo, MS, Florian Langer, MD, Theresa Robson, BS, Hina Desai, MS, Monica Davila, Ph.D., Mildred Amaya, MS, John L. Francis, Ph.D.

Blood (2008) 112 (11): 114.

https://doi.org/10.1182/blood.V112.11.114.114

Published: 2008

Journal Articles

Microparticle-Associated Tissue Factor: A Molecular Link Between Coagulation Activation, Inflammation and Disease Progression in Early-Stage Prostate Cancer?

Katja Haubold, Michael Rink, Brigitte Spath, Ali Amirkhosravi, John L. Francis, Barbara Eifrig, Carsten Bokemeyer, MD, Florian Langer

Blood (2008) 112 (11): 3813.

https://doi.org/10.1182/blood.V112.11.3813.3813

Published: 2008

Journal Articles

High-Dose Calcitriol Modulates the Expression and Activity of Tissue Factor and Thrombomodulin in Tumor Cells.

Enriqueta Coll-Sangrona, PhD, Ali Amirkhosravi, Ph.D., Alshad S. Lalani, Ph.D., Liza Robles, M.S., Hina Desai, M.S., Mildred Amaya, M.S., John L. Francis, Ph.D.

Blood (2007) 110 (11): 921.

https://doi.org/10.1182/blood.V110.11.921.921

Published: 2007

Journal Articles

Tissue Factor-Bearing Microparticles Derived from Tumor Cells: Impact on Coagulation Activation.

Monica Davila, PhD, Ali Amirkhosravi, PhD, Enriqueta Coll, PhD, Robles D. Liza, MS, John Francis, PhD

Blood (2006) 108 (11): 1757.

https://doi.org/10.1182/blood.V108.11.1757.1757

Published: 2006

Journal Articles

Mechanisms of Platelet Activation by Antithymocyte Globulin (ATG).

Florian Langer, Francis A. Ayuk, Ali Amirkhosravi, Brigitte Spath, Todd Meyer, Theresa Robson, Liza Robles, Guy Marx, Simon D. Lytton, Katharina Holstein, Barbara Eifrig, Carsten Bokemeyer, Axel R. Zander, Nicolaus Kroeger

Blood (2006) 108 (11): 3905.

https://doi.org/10.1182/blood.V108.11.3905.3905

Published: 2006

Journal Articles

Targeting Angiogenesis in Cancer: Bevacizumab-Induced Platelet Activation as a Possible Cause for Unexpected Arterial Thromboembolic Events in Clinical Trials.

Todd Meyer, PhD, Theresa Robson, B.S., Ali Amirkhosravi, Ph.D., Florian Langer, M.D., Hina Desai, M.S., Mildred Amaya, M.S., Pierre Elias, John L. Francis, Ph.D.

Blood (2006) 108 (11): 1091.

https://doi.org/10.1182/blood.V108.11.1091.1091

Published: 2006

Journal Articles

Prospective Evaluation of Laboratory Tests for the Diagnosis of Heparin-Induced Thrombocytopenia.

John L. Francis, PhD, Alane Drexler, MS, RN, Mary Kathryn Duncan, RN, Hina Desai, MSc, Mildred Amaya, MSc, Theresa Robson, Todd V. Meyer, PhD, Edward Reyes, MSc, Kristin Rathmann, MSc, Ali Amirkhosravi, PhD

Blood (2006) 108 (11): 1051.

https://doi.org/10.1182/blood.V108.11.1051.1051

Published: 2006

Journal Articles

Blood-Borne, but Not Endothelial CD40 Promotes Experimental Lung Metastasis.

Ali Amirkhosravi, PhD, Susan B. Ingersoll, Ph.D., Theresa Robson, BS, Florian Langer, M.D., Jamie Walker, BS, John L. Francis, Ph.D.

Blood (2006) 108 (11): 1092.

https://doi.org/10.1182/blood.V108.11.1092.1092

Published: 2006

Journal Articles

Functional and Antigenic Detection of Intravascular Tissue Factor (TF).

Florian Langer, Ali Amirkhosravi, Brigitte Spath, Hina Desai, Mildred Amaya, Judith Dierlamm, Barbara Eifrig, John L. Francis, Carsten Bokemeyer

Blood (2006) 108 (11): 4002.

https://doi.org/10.1182/blood.V108.11.4002.4002

Published: 2006

Journal Articles

Hypercoagulability in Ovarian Cancer Revisited: A Prospective Analysis of Coagulation and Platelet Activation Markers.

Ali Amirkhosravi, PhD, Glenn Bigsby, IV, D.O., Hina Desai, M.S., Mildred Amaya, M.S., Enriqueta Coll, Ph.D., Liza Robles, M.S., Patricia Faust, R.N., Florian Langer, M.D., Alane Drexler, R.N., Edward Reyes, M.S., John L. Francis, Ph.D.

Blood (2006) 108 (11): 1762.

https://doi.org/10.1182/blood.V108.11.1762.1762

Published: 2006

NARROW

Blockade of the Neonatal Fc Receptor (FcRn) Represents an Effective Mechanism for the Removal of Pathogenic Autoantibodies in Primary Immune Thrombocytopenia

CD32a antibodies induce thrombocytopenia and type II hypersensitivity reactions in FCGR2A mice

β 2 -Glycoprotein 1 Antibodies Directly Activate the Platelet IgG Receptor, FcγRIIa, and Cause Thrombosis in FCGR2A Transgenic but Not in Wild Type Mice

Differential Effects of Protein Disulfide Isomerase (PDI) Inhibitors On the Expression of Tissue Factor Procoagulant Activity (TF PCA) by AML Blasts

Assessment of Protein C Anticoagulant Pathway by Thrombin Generation Assay in the Presence of Endothelial Cells

Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice

Comparison of Platelet-Activating Potential of Bevacizumab+VEGF and Aflibercept+VEGF Complexes

CDP7657, and Other Anti-CD40L Antibody Formats Lacking a Functional Fc Region, Do Not Cause Platelet Activation In Vitro

Role of Protein Disulfide Isomerase (PDI) In the Expression of Tissue Factor (TF) Procoagulant Activity on Apoptotic Myeloblasts

Mechanism of Thrombocytopenia Induced by Anti-CD40 Ligand Immune Complexes and the Prevalence of CD40 Ligand Autoantibodies in Patients with Thrombotic Autoimmune Disorders

Bevacizumab Immune Complexes Induce Thrombocytopenia and Thrombosis in Mice Transgenic for Human IgG Receptor FcYIIa

Microparticle-Associated Tissue Factor: A Molecular Link Between Coagulation Activation, Inflammation and Disease Progression in Early-Stage Prostate Cancer?

High-Dose Calcitriol Modulates the Expression and Activity of Tissue Factor and Thrombomodulin in Tumor Cells.

Tissue Factor-Bearing Microparticles Derived from Tumor Cells: Impact on Coagulation Activation.

Mechanisms of Platelet Activation by Antithymocyte Globulin (ATG).

Targeting Angiogenesis in Cancer: Bevacizumab-Induced Platelet Activation as a Possible Cause for Unexpected Arterial Thromboembolic Events in Clinical Trials.

Prospective Evaluation of Laboratory Tests for the Diagnosis of Heparin-Induced Thrombocytopenia.

Blood-Borne, but Not Endothelial CD40 Promotes Experimental Lung Metastasis.

Functional and Antigenic Detection of Intravascular Tissue Factor (TF).

Hypercoagulability in Ovarian Cancer Revisited: A Prospective Analysis of Coagulation and Platelet Activation Markers.

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American Society of Hematology

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American Society of Hematology

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