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Allison Berger, PhD
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Journal Articles

Immunomodulatory Effects of Pevonedistat, a NEDD8-Activating Enzyme (NAE) Inhibitor, in Chronic Lymphocytic Leukemia (CLL)

Scott R Best, BS, Adam Kittai, MD, Taylor Rowland, BS, Nur Bruss, BS, Stephen E Spurgeon, MD, Allison Berger, PhD, Amy Moran, PhD, Alexey V Danilov, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2946.
https://doi.org/10.1182/blood-2018-99-115086
Published: 2018
Journal Articles

TAK-243, a Small Molecule Inhibitor of Ubiquitin-Activating Enzyme (UAE), Induces ER Stress and Apoptosis in CLL Cells

Scott R Best, BS, Taylor Rowland, BS, Cody Paiva, BS, Nur Bruss, BS, Stephen E Spurgeon, MD, Allison Berger, PhD, Alexey V Danilov, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1867.
https://doi.org/10.1182/blood-2018-99-114964
Published: 2018
Journal Articles

TAK-243 Is a Selective UBA1 Inhibitor That Displays Preclinical Activity in Acute Myeloid Leukemia (AML)

Samir H. Barghout, BSPharm, MSc, Parasvi Patel, BSc (Hons), Xiaoming Wang, G. Wei Xu, Simon Kavanagh, Marcela Gronda, MSc, Rose Hurren, BSc, Danny V. Jeyaraju, PhD, Neil MacLean, Marc Hyer, PhD, Allison Berger, PhD, Tary Traore, Michael Sintchak, Michael Milhollen, Mark D. Minden, MD PhD, Razq Hakem, PhD, Aaron D. Schimmer, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 814.
https://doi.org/10.1182/blood.V130.Suppl_1.814.814
Published: 2017
Journal Articles

TAK-243, a Small Molecule Inhibitor of Ubiquitin-Activating Enzyme (UAE), Induces ER Stress and Apoptosis in Diffuse Large B-Cell Lymphoma (DLBCL) Cells

Scott R Best, Cody Paiva, Taylor Rowland, Bhargava Sreekantham, Stephen E Spurgeon, MD, Allison Berger, PhD, Alexey Danilov, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1533.
https://doi.org/10.1182/blood.V130.Suppl_1.1533.1533
Published: 2017
Journal Articles

Altered Expression of Neddylation Pathway Proteins in Myelodysplastic Syndromes

Fatemeh Majidi, MD, Judith Neukirchen, MD, Simon Brille, Iris Fey, BSc., Frank Neumann, MDPhD, Allison Berger, PhD, Ron-Patrick Cadeddu, PhD, Martina Rudelius, MD, Ulrich Germing, MD, Rainer Haas, MD, Norbert Gattermann, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5298.
https://doi.org/10.1182/blood.V130.Suppl_1.5298.5298
Published: 2017
Journal Articles

Ninlaro (ixazomib) and Brentuximab Vedotin (ADCETRIS) Combination Results in Synergistic Antitumor Activity in Mouse Models of CD30 Positive Anaplastic Large Cell Lymphoma

Nibedita Chattopadhyay, PhD, Sakeena Syed, Yuhong Zhang, Jie Yu, M.S., Dan He McDougall, Lunyin Yu Yu, Stephen Tirrell, PhD, Allison Berger, PhD, Helgi van de Velde, MD PhD, Christopher Tremblay, Dirk Huebner, MD
Journal: Blood
Blood (2016) 128 (22): 1842.
https://doi.org/10.1182/blood.V128.22.1842.1842
Published: 2016
Journal Articles

The Anti-Tumor Effect of the Ubiquitin-Activating Enzyme (UAE) Inhibitor TAK-243 on Pre-Clinical Models of Multiple Myeloma

Junling Zhuang, MD PhD, Hans Lee, MD, Isere Kuiatse, PhD, Hua Wang, PhD, Fazal Shirazi, PhD, Allison Berger, PhD, Marc Hyer, PhD, Nibedita Chattopadhyay, PhD, Sakeena Syed, Judy Qiuju Shi, Jie Yu, M.S., Vaishali Shinde, Anna Kreshock, Stephen Tirrell, PhD, Saurabh Menon, PhD, Richard Julian Jones, PhD, Robert Z. Orlowski, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3296.
https://doi.org/10.1182/blood.V128.22.3296.3296
Published: 2016
Journal Articles

Mutational Analysis of Tumor Samples From Patients with Relapsed or Refractory Multiple Myeloma (MM) Highlights the Prevalence of RAS/RAF Pathway Activation and Demonstrates Previously Unreported Mutations in Known Cancer Genes

George Mulligan, PhD, David I Lichter, MS, Alessandra Di Bacco, PhD, Stephen J Blakemore, PhD, Allison Berger, PhD, Erik Koenig, Hugues Bernard, William L. Trepicchio, PhD, Bin Li, PhD, Sagar Lonial, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Pieter Sonneveld, MD, PhD, Jesús F San Miguel, MD PhD, Dixie-Lee Esseltine, MD, FRCPC, Matthew Schu, MS
Journal: Blood
Blood (2011) 118 (21): 1377.
https://doi.org/10.1182/blood.V118.21.1377.1377
Published: 2011