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Scott R Best
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Journal Articles

Pharmacologic Inhibition of SUMO-Activating Enzyme Potentiates Interferon Response and T Cell-Mediated Anti-Tumor Immunity in Chronic Lymphocytic Leukemia (CLL) and Lymphoma Models

Vi Lam, Xiaoguang Wang, Scott R Best, Nur Bruss, Tingting Liu, Olga Danilova, Tanya Siddiqi, Nathan Pennock, Alexey V. Danilov
Journal: Blood
Blood (2021) 138 (Supplement 1): 3719.
https://doi.org/10.1182/blood-2021-146347
Published: 2021
Journal Articles

Neddylation Pathway Regulates Treg Differentiation and T Cell Function in Chronic Lymphocytic Leukemia (CLL) Ex Vivo and Murine In Vivo Studies

Scott R Best, BS, Vi Lam, Nur Bruss, BS, Taylor Hashiguchi Rowland, BS, Adam S. Kittai, MD, Tingting Liu, Allison J Berger, PhD, Alexey Danilov, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4313.
https://doi.org/10.1182/blood-2019-123600
Published: 2019
Journal Articles

Pharmacologic Inhibition of SUMO-Activating Enzyme (SAE) with TAK-981 Augments Interferon Signaling and Regulates T Cell Differentiation in Ex Vivo studies of Chronic Lymphocytic Leukemia (CLL)

Vi Lam, Scott R Best, BS, Nur Bruss, BS, Tingting Liu, Taylor Hashiguchi Rowland, BS, Dennis Huszar, PhD, Alexey Danilov, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1760.
https://doi.org/10.1182/blood-2019-127539
Published: 2019
Journal Articles

SYK Inhibitor Entospletinib in Combination with Obinutuzumab Demonstrates Efficacy in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)

Adam S. Kittai, MD, Scott R Best, BS, Bria Thurlow, BSc, Basak Gokcora, Andrzej Stadnik, MPH, BS, Renee MacKinnon, Taylor Hashiguchi Rowland, BS, Daniel O. Persky, MD, Byung Park, PhD, Stephen E Spurgeon, MD, Alexey Danilov, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4295.
https://doi.org/10.1182/blood-2019-123586
Published: 2019
Journal Articles

TAK-243, a Small Molecule Inhibitor of Ubiquitin-Activating Enzyme (UAE), Induces ER Stress and Apoptosis in CLL Cells

Scott R Best, BS, Taylor Rowland, BS, Cody Paiva, BS, Nur Bruss, BS, Stephen E Spurgeon, MD, Allison Berger, PhD, Alexey V Danilov, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1867.
https://doi.org/10.1182/blood-2018-99-114964
Published: 2018
Journal Articles

Pevonedistat, a Small Molecule Inhibitor of NEDD8-Activating Enzyme (NAE), Induces Cell Cycle Deregulation, Anaphase Catastrophe, and Apoptosis in T-Cell Lymphoma Cells

Adam Kittai, MD, Scott R Best, BS, Taylor Rowland, BS, Nur Bruss, BS, Craig Okada, MD PhD, Alexey V Danilov, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1667.
https://doi.org/10.1182/blood-2018-99-113179
Published: 2018
Journal Articles

Immunomodulatory Effects of Pevonedistat, a NEDD8-Activating Enzyme (NAE) Inhibitor, in Chronic Lymphocytic Leukemia (CLL)

Scott R Best, BS, Adam Kittai, MD, Taylor Rowland, BS, Nur Bruss, BS, Stephen E Spurgeon, MD, Allison Berger, PhD, Amy Moran, PhD, Alexey V Danilov, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2946.
https://doi.org/10.1182/blood-2018-99-115086
Published: 2018
Journal Articles

TAK-243, a Small Molecule Inhibitor of Ubiquitin-Activating Enzyme (UAE), Induces ER Stress and Apoptosis in Diffuse Large B-Cell Lymphoma (DLBCL) Cells

Scott R Best, Cody Paiva, Taylor Rowland, Bhargava Sreekantham, Stephen E Spurgeon, MD, Allison Berger, PhD, Alexey Danilov, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1533.
https://doi.org/10.1182/blood.V130.Suppl_1.1533.1533
Published: 2017