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Andreas Gnirke
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Journal Articles

B Cell-Restricted Depletion of Dnmt3a Activates Notch Signaling and Causes Chronic Lymphocytic Leukemia

Shanye Yin, Anat Biran, Helene Kretzmer, Elisa Ten Hacken, Salma Parvin, Fabienne Lucas, Mohamed Uduman, Catherine Gutierrez, Nathan J Dangle, Leah Billington, Fara Regis, Laura Z. Rassenti, Arman W. Mohammad, Mei Zheng, Elizabeth Witten, Thomas J. Kipps, Jon C. Aster, Andreas Gnirke, Donna S. Neuberg, Anthony G. Letai, Lili Wang, Ruben D. Carrasco, Alexander Meissner, Catherine J. Wu
Journal: Blood
Blood (2021) 138 (Supplement 1): 249.
https://doi.org/10.1182/blood-2021-150789
Published: 2021
Journal Articles

Robust Discovery of Candidate DNA Methylation Cancer Drivers

Heng Pan, PhD, Loïc Renaud, MD MSc, Ronan Chaligne, PhD, Johannes Bloehdorn, MD, Eugen Tausch, MD, Daniel Mertens, PhD, Anna-Maria Fink, MD, Kirsten Fischer, MD, Chao Zhang, PhD, Doron Betel, PhD, Andreas Gnirke, Marcin Imielinski, Jerome Moreaux, PhD, Michael Hallek, Alexander Meissner, PhD, Stephan Stilgenbauer, MD, Catherine J. Wu, MD, Olivier Elemento, PhD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-136830
Published: 2020
Journal Articles

Deciphering the Role of Locally Disordered DNA Methylation on CLL Development In Vivo

Anat Biran, PhD, Helene Kretzmer, PhD, Shanye Yin, PhD, Leah Billington, BA, Fara Faye Regis, BS, Arman W. Mohammad, BA, Andreas Gnirke, Donna S Neuberg, ScD, Ruben D. Carrasco, MD PhD, Alexander Meissner, PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1737.
https://doi.org/10.1182/blood-2019-130744
Published: 2019
Journal Articles

Multimodal Single-Cell Profiling Defines the Epigenetic Determinants of Chronic Lymphocytic Leukemia Evolution

Ronan Chaligne, PhD, Federico Gaiti, PhD, Franco Izzo, PhD, Steven Kothen-Hill, MS, Hongcang Gu, Kevin Huang, BS, Davide Risso, PhD, Rafael Schulman, BS, Ryan M Brand, Stanley C Lee, PhD, Asaf Poran, Kye-Tae Kim, PhD, Alessandro Pastore, Alicia Alonso, Andreas Gnirke, Catherine J. Wu, MD, Omar I Abdel-Wahab, MD, Alexander Meissner, PhD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1312.
https://doi.org/10.1182/blood-2018-99-115596
Published: 2018
Journal Articles

Single-Cell Joint Methylomics and Transcriptomics Define the Epigenetic Evolution and Lineage Histories of Chronic Lymphocytic Leukemia

Ronan Chaligne, PhD, Federico Gaiti, PhD, Steven Kothen-Hill, MS, Hongcang Gu, Kevin Huang, BS, Rafael Schulman, Kye-Tae Kim, PhD, Evan Biederstedt, Lili Wang, MD PhD, Martin J. Aryee, PhD, Andreas Gnirke, Catherine J. Wu, MD, Alexander Meissner, PhD, Dan A. Landau, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 55.
https://doi.org/10.1182/blood.V130.Suppl_1.55.55
Published: 2017
Journal Articles

Single Cell Bisulfite Sequencing Defines Epigenetic Diversification in Chronic Lymphocytic Leukemia

Dan A. Landau, MD PhD, Kendell Clement, Hongcang Gu, Evan Biederstedt, MA, Divy Kangeyan, Steven Hill, Lili Wang, MD PhD, Martin Aryee, PhD, Andreas Gnirke, Alex Meissner, Catherine J Wu, MD
Journal: Blood
Blood (2016) 128 (22): 1047.
https://doi.org/10.1182/blood.V128.22.1047.1047
Published: 2016