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Angela Howes
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Journal Articles

Residual Disease Kinetics Among Patients with High-Risk Factors Treated with First-Line Fixed-Duration Ibrutinib Plus Venetoclax (Ibr+Ven) Versus Chlorambucil Plus Obinutuzumab (Clb+O): The Glow Study

Carsten U Niemann, Talha Munir, Carol Moreno, Carolyn Owen, George A Follows, Ohad Benjamini, Ann Janssens, Mark-David Levin, Anders Österborg, Tadeusz Robak, Martin Šimkovič, Sergey Voloshin, Vladimir I. Vorobyev, Munci Yagci, Loic Ysebaert, Keqin Qi, Qianaya Qi, Lori Parisi, Srimathi Srinivasan, Natasha Schuier, Kurt Baeten, Angela Howes, Donne Bennett Caces, Arnon P. Kater
Journal: Blood
Blood (2022) 140 (Supplement 1): 228–230.
https://doi.org/10.1182/blood-2022-156070
Published: 2022
Journal Articles

A Validated Risk Model for Overall Survival in Relapsed/Refractory Chronic Lymphocytic Leukemia Applicable to Patients Treated with Novel Therapies and Standard of Care

Jacob D. Soumerai, MD, Ai Ni, PhD, Mohamed Darif, PhD, Anil Londhe, PhD, Guan Xing, PhD, Julie Huang, PhD, Ming Lin, PhD, John C. Byrd, MD, Asher A. Chanan-Khan, MD, Richard R. Furman, MD, Michael Hallek, MD, Peter Hillmen, MBChB, PhD, Jeffrey Jones, MD, Jeffrey P. Sharman, MD, Lucille Ferrante, MD, Vijay Reddy, MD PhD, Lyndah K. Dreiling, MD, Henry Adewoye, MD, Ronald Dubowy, MD, Angela Howes, PhD, Danelle F. James, MD MAS, Andrew D. Zelenetz, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4303.
https://doi.org/10.1182/blood.V130.Suppl_1.4303.4303
Published: 2017
Journal Articles

11q Deletion (del11q) Is Not a Prognostic Factor for Adverse Outcomes for Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Treated with Ibrutinib: Pooled Data from 3 Randomized Phase 3 Studies

Thomas J. Kipps, MD, PhD, Peter Hillmen, Fatih Demirkan, MD, Sebastian Grosicki, MD PhD, Steven E. Coutre, MD, Jacqueline C. Barrientos, MD, Paul M. Barr, Ann Janssens, MD, John C. Byrd, MD, Susan M. O'Brien, MD, Graeme Fraser, MD, Ulrich Jaeger, MD, Paula Cramer, MD, Stephan Stilgenbauer, MD, Asher A. Chanan-Khan, MD, Mariya Salman, PhD, Isabelle Solman, MS, Mei Cheng, PhD, Charles Phelps, MSc, Joi Ninomoto, PharmD, Angela Howes, Danelle F. James, MD MAS, Michael Hallek
Journal: Blood
Blood (2016) 128 (22): 2042.
https://doi.org/10.1182/blood.V128.22.2042.2042
Published: 2016
Journal Articles

Early Changes in Circulating T-Cell Immune Profiles in Patients with Relapsed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Data from the Phase 3, Double-Blind HELIOS Trial

Rajendra Damle, PhD, Michael Schaffer, PhD, Shalini Chaturvedi, PhD, Charles Phelps, MSc, Regina Aquino, MSc, Michelle Mahler, MD, Mariya Salman, PhD, Angela Howes, PhD, Javier Loscertales, MD PhD, Marek Trneny, MD, Dina Ben Yehuda, MD, Alexander Pristupa, MD, Asher A. Chanan-Khan, MD, Sriram Balasubramanian, PhD
Journal: Blood
Blood (2016) 128 (22): 4397.
https://doi.org/10.1182/blood.V128.22.4397.4397
Published: 2016
Journal Articles

Systemic Exposure of Rituximab Increased By Ibrutinib: Pharmacokinetic Results from the Helios Trial

Paula Cramer, MD, Fatih Demirkan, MD, Graeme Fraser, MD, Alexander Pristupa, MD, Nancy L Bartlett, MD, Marie-Sarah Dilhuydy, MD, Javier Loscertales, Abraham Avigdor, MD, Simon A. Rule, MD, Olga Samoilova, MD, Andre Goy, MD, Siddhartha Ganguly, MD, Italo Poggesi, ChemD, Silvia Maria Lavezzi, Giuseppe De Nicolao, Jan de Jong, PhD, Martine Neyens, Mariya Salman, PhD, Angela Howes, PhD, Michelle Mahler, MD
Journal: Blood
Blood (2016) 128 (22): 4403.
https://doi.org/10.1182/blood.V128.22.4403.4403
Published: 2016
Journal Articles

Ibrutinib Plus Bendamustine/Rituximab (BR) Is Associated with Greater Reductions in Fatigue Than Placebo Plus BR Among Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia and Fatigue

Shana Traina, PhD, Graeme Fraser, MDFRCPC, Paula Cramer, MD, Rodrigo Santucci Silva, MD, Sebastian Grosicki, MD PhD, Marie Sarah Dilhuydy, MD, Michelle Mahler, MD, Mariya Salman, PhD, Angela Howes, PhD
Journal: Blood
Blood (2015) 126 (23): 267.
https://doi.org/10.1182/blood.V126.23.267.267
Published: 2015
Journal Articles

Impact of High Risk Prognostic Parameters and Addition of Ibrutinib to Bendamustine/Rituximab (BR) on Outcomes for Patients with Relapsed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) from the Phase 3 Double-Blind HELIOS Trial

Asher Chanan-Khan, MD, Paula Cramer, MD, Graeme Fraser, MDFRCPC, Rodrigo Santucci Silva, MD, Sebastian Grosicki, MD PhD, Aleksander Pristupa, MD, Marie Sarah Dilhuydy, MD, Andre Goy, MD, Anthony R. Mato, MD MSCE, Rajendra Damle, PhD, Charles Phelps, MS, Michelle Mahler, MD, Mariya Salman, PhD, Michael Schaffer, PhD, Angela Howes, PhD, Sriram Balasubramanian, PhD
Journal: Blood
Blood (2015) 126 (23): 1732.
https://doi.org/10.1182/blood.V126.23.1732.1732
Published: 2015
Journal Articles

Improvement of Quality of Response with Ibrutinib Plus Bendamustine/Rituximab Vs Placebo Plus Bendamustine/Rituximab for Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

Paula Cramer, MD, Asher Chanan-Khan, MD, Graeme Fraser, MDFRCPC, Fatih Demirkan, MD, Rodrigo Santucci Silva, MD, Halyna Pylypenko, MD, Sebastian Grosicki, MD PhD, Ann Janssens, MD, Andre Goy, MD, Jiri Mayer, Prof., MD, Marie Sarah Dilhuydy, MD, Javier Loscertales, MD PhD, Nancy L. Bartlett, MD, Abraham Avigdor, MD, Simon Rule, MD, Steven Sun, PhD, Charles Phelps, MS, Michelle Mahler, MD, Mariya Salman, PhD, Michael Schaffer, PhD, Sriram Balasubramanian, PhD, Angela Howes, PhD, Michael Hallek, MD
Journal: Blood
Blood (2015) 126 (23): 2938.
https://doi.org/10.1182/blood.V126.23.2938.2938
Published: 2015
Journal Articles

Comparing Single-Agent Ibrutinib, Bendamustine Plus Rituximab (BR) and Ibrutinib Plus BR in Patients with Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): An Indirect Comparison of the RESONATE and HELIOS Trials

Peter Hillmen, MB, ChB, PhD, Graeme Fraser, MDFRCPC, Jeffrey Jones, MD MPH, Simon Rule, MD, Susan O'Brien, MD, Marie Sarah Dilhuydy, MD, Ulrich Jaeger, MD, Sebastian Grosicki, MD PhD, Florence Cymbalista, MD PhD, Steven Sun, PhD, Joi Ninomoto, PharmD, Michelle Mahler, MD, Mei Cheng, PhD, Joris Diels, Fong Clow, ScD, Mariya Salman, PhD, Danelle F. James, MD MAS, Angela Howes, PhD, Asher Chanan-Khan, MD
Journal: Blood
Blood (2015) 126 (23): 2944.
https://doi.org/10.1182/blood.V126.23.2944.2944
Published: 2015
Journal Articles

Insights into the Management of Adverse Events in Patients with Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Experience from the Phase 3 HELIOS Study of Ibrutinib Combined with Bendamustine/Rituximab

Asher Chanan-Khan, MD, Paula Cramer, MD, Fatih Demirkan, MD, Graeme Fraser, MDFRCPC, Rodrigo Santucci Silva, MD, Halyna Pylypenko, MD, Sebastian Grosicki, MD PhD, Ann Janssens, MD, Aleksander Pristupa, MD, Andre Goy, MD, Jiri Mayer, Prof., MD, Marie Sarah Dilhuydy, MD, Javier Loscertales, MD PhD, Nancy L. Bartlett, MD, Abraham Avigdor, MD, Simon Rule, MD, Steven Sun, PhD, Charles Phelps, MS, Michelle Mahler, MD, Mariya Salman, PhD, Angela Howes, PhD, Michael Hallek, MD
Journal: Blood
Blood (2015) 126 (23): 2936.
https://doi.org/10.1182/blood.V126.23.2936.2936
Published: 2015