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Anna Borodovsky
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Journal Articles

Development of Liver-Specific Thrombopoietin Targeted Sirnas: Impact on Platelet Count, Megakaryocyte Mass, and Hematopoietic Progenitors in Normal and MPN Murine Models

Dhruv Desai, MSc, Anna Borodovsky, PhD, Wendell P Davis, DVM DACVP, Rohan Degaonkar, Kristina Yucius, Kellie D'Angelo, MLS(ASCP)CM, Paul Gedman, BS, Donna Marie Williams, PhD, Ophelia Rogers, Zhizhuang Joe Zhao, PhD, Jerry L. Spivak, MD, Alison R. Moliterno, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4329.
https://doi.org/10.1182/blood-2018-99-117142
Published: 2018
Journal Articles

A Subcutaneously Administered Investigational RNAi Therapeutic (ALN-CC5) Targeting Complement C5 for Treatment of PNH and Complement-Mediated Diseases: Preliminary Phase 1/2 Study Results in Patients with PNH

Anita Hill, Anna Gaya Valls, Morag Griffin, Talha Munir, Anna Borodovsky, Nori Kawahata, Helen Mclean, Kelvin Shi, Angela M. Partisano, Jae Kim, Nader Najafian, Alvaro Urbano
Journal: Blood
Blood (2016) 128 (22): 3891.
https://doi.org/10.1182/blood.V128.22.3891.3891
Published: 2016
Journal Articles

A Subcutaneously Administered Investigational RNAi Therapeutic (ALN-CC5) Targeting Complement C5 for Treatment of PNH and Complement-Mediated Diseases: Interim Phase 1 Study Results

Anita Hill, Jorg Taubel, Jim Bush, Anna Borodovsky, Noriyuki Kawahata, Helen Mclean, Christine Powell, Prasoon Chaturvedi, Garvin Warner, Pushkal Garg, Benny Sorensen
Journal: Blood
Blood (2015) 126 (23): 2413.
https://doi.org/10.1182/blood.V126.23.2413.2413
Published: 2015
Journal Articles

Aln-CC5, an Investigational RNAi Therapeutic Targeting C5 for Complement Inhibition

Anna Borodovsky, PhD, Kristina Yucius, Andrew Sprague, Nirmal K Banda, PhD, V. Michael Holers, MD, Akshay Vaishnaw, MD PhD, Martin Maier, PhD, Rajeev Kallanthottathil, PhD, Klaus Charisse, PhD, Satya Kuchimanchi, PhD, Muthiah Manoharan, PhD, David J Salant, MD, Kevin Fitzgerald, PhD, Rachel Meyers, PhD, Benny Sorensen, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1606.
https://doi.org/10.1182/blood.V124.21.1606.1606
Published: 2014
Journal Articles

Development Of RNAi Therapeutics Targeting The Complement Pathway

Anna Borodovsky, PhD, Kristina Yucius, Andrew Sprague, James Butler, PhD, Shannon Fishman, BS, Tuyen Nguyen, Akshay Vaishnaw, MD, PhD, Martin Maier, PhD, Rajeev Kallanthottathil, PhD, Satya Kuchimanchi, PhD, Muthiah Manoharan, PhD, Rachel Meyers, PhD, Kevin Fitzgerald, PhD
Journal: Blood
Blood (2013) 122 (21): 2471.
https://doi.org/10.1182/blood.V122.21.2471.2471
Published: 2013