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Journal Articles

NF-κB-Dependent Activation of the Proteasome Components, PSMD1 and PSMD3, As a Mechanism of Resistance to Imatinib

Idaly Maria Olivas, BS, Joshua Lara, BS, Rebecca Ellwood, MS, Carme Ripoll Fiol, MS, Andres J Rubio, MS, Alfonso Enrique Bencomo, PhD, Mayra Alejandra Gonzalez, BS, Georgios Nteliopoulos, PhD, Alistair Reid, BSc, PhD, Dragana Milojkovic, MBBS, MD, Jane Apperley, MB, ChB, MD, Jamshid Sorouri Khorashad, MD PhD FRCPath, Anna M. Eiring, PhD

Blood (2019) 134 (Supplement_1): 2923.

https://doi.org/10.1182/blood-2019-126963

Published: 2019

Journal Articles

Retrospective Study of Incidence and Survival for Patients with Hematologic Malignancies Residing at the U.S./Mexico Border

Alfonso Enrique Bencomo, PhD, Andres J Rubio, MS, Mayra Alejandra Gonzalez, BS, Idaly Maria Olivas, BS, Joshua Lara, BS, Kiran Ghimire, MD, Osvaldo Padilla, MD, Angelica Padilla, MD, Nawar Hakim, MD, Attilio Orazi, MD, Javier Corral, MD, Alexander Philipovskiy, MD PhD, Sumit Gaur, MBBS, Anna M. Eiring, PhD

Blood (2019) 134 (Supplement_1): 4782.

https://doi.org/10.1182/blood-2019-126150

Published: 2019

Journal Articles

Combining Dasatinib and AC220 Reduces Stroma-Based pSTAT5Y694 in FLT3-ITD+ AML and Overcomes FLT3 TKI Resistance

Ami B. Patel, MD, Anthony D. Pomicter, MS, Dongqing Yan, Anna M. Eiring, PhD, Anca Franzini, PhD, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD

Blood (2018) 132 (Supplement 1): 2641.

https://doi.org/10.1182/blood-2018-99-117276

Published: 2018

Journal Articles

Inhibition of Nucleocytoplasmic Export Enhances Selective Elimination of Leukemic Stem Cells in Chronic Myeloid Leukemia

Hein Than, MD FRCPath, MRCP, Anthony D. Pomicter, MS, Clinton C. Mason, PhD, Anna M. Eiring, PhD, William L. Heaton, MS, Dongqing Yan, Anna Senina, MS, Phillip M. Clair, MS, Tessa L. Holyoake, MD PhD FRCP, FRCPath, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD

Blood (2017) 130 (Supplement 1): 42.

https://doi.org/10.1182/blood.V130.Suppl_1.42.42

Published: 2017

Journal Articles

Selective Inhibition of Nucleocytoplasmic Transport Overcomes Ruxolitinib Resistance in Myelofibrosis

Dongqing Yan, Srinivas K. Tantravahi, MBBS, Anthony D. Pomicter, MS, Clinton C. Mason, PhD, Anna Senina, MS, Qiang Wang, PhD, Jamshid Sorouri Khorashad, MD PhD FRCPath, Hein Than, MD FRCPath, MRCP, Phillip M. Clair, MS, William L. Heaton, MS, Anna M. Eiring, PhD, Josef T. Prchal, MD, Sabina I. Swierczek, PhD, Erkan Baloglu, Sharon Shacham, PhD MBA, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD

Blood (2017) 130 (Supplement 1): 1660.

https://doi.org/10.1182/blood.V130.Suppl_1.1660.1660

Published: 2017

Journal Articles

Loss of G0S2 in Kinase-Independent TKI Resistance and Blastic Transformation of CML

Anna M. Eiring, PhD, Jonathan Ahmann, Clinton C. Mason, PhD, Ethan Dmitrovsky, MD, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD

Blood (2017) 130 (Supplement 1): 4173.

https://doi.org/10.1182/blood.V130.Suppl_1.4173.4173

Published: 2017

Journal Articles

A Novel JAK2 Mutation Confers Cytokine-Independence in the Absence of a Type I Dimeric Cytokine Receptor

Ami B. Patel, MD, Anca Franzini, PhD, Emilie Leroy, PhD, Dongqing Yan, Anna M. Eiring, PhD, Stefan N. Constantinescu, MD PhD, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD

Blood (2017) 130 (Supplement 1): 4212.

https://doi.org/10.1182/blood.V130.Suppl_1.4212.4212

Published: 2017

Journal Articles

Stroma-Based Activation of pSTAT3 Y705 Confers Resistance to FLT3 Inhibitors in FLT3 ITD-Positive AML

Ami Patel, MD, Anthony D. Pomicter, MS, Anna M. Eiring, PhD, Than Hein, MBBS, William L. Heaton, MS, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD

Blood (2016) 128 (22): 34.

https://doi.org/10.1182/blood.V128.22.34.34

Published: 2016

Journal Articles

Selective Inhibition of Nuclear Cytoplasmic Transport As a New Treatment Paradigm in Myelofibrosis

Dongqing Yan, PhD, Srinivas K. Tantravahi, MD, Anthony D. Pomicter, MS, Anna Senina, MS, Kevin C. Gantz, Hannah M. Redwine, Josef T. Prchal, MD, Sabina Swierczek, PhD, Phillip M. Clair, MS, Anna M. Eiring, PhD, Erkan Baloglu, PhD MBA, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD

Blood (2016) 128 (22): 636.

https://doi.org/10.1182/blood.V128.22.636.636

Published: 2016

Journal Articles

MS4A3: A New Player in Leukemic Stem Cell Survival in Chronic Myeloid Leukemia

Anna M. Eiring, PhD, Jamshid S. Khorashad, MD PhD, Anupriya Agarwal, PhD, Clinton C. Mason, PhD, Russell Bell, PhD, Anna Senina, MS, Anthony D. Pomicter, MS, Fan Yu, MD, Hannah M. Redwine, Amber D. Bowler, Phillip M. Clair, MS, Srinivas K. Tantravahi, MD, Shannon K. McWeeney, Brian J. Druker, MD, Derek L. Stirewalt, Vivian Oehler, MD, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD

Blood (2016) 128 (22): 934.

https://doi.org/10.1182/blood.V128.22.934.934

Published: 2016

Journal Articles

MS4A3 Improves Imatinib Response and Survival in BCR-ABL1 Primary TKI Resistance and in Blastic Transformation of Chronic Myeloid Leukemia

Anna M. Eiring, PhD, Jamshid S. Khorashad, MD PhD, Anupriya Agarwal, PhD, Clinton C. Mason, PhD, Fan Yu, MD, Hannah M. Redwine, Amber D. Bowler, Kevin C. Gantz, Kimberly R. Reynolds, MS, Phillip M. Clair, MS, David J. Anderson, MBA, Srinivas K Tantravahi, Shannon K. McWeeney, PhD, Brian J. Druker, MD, Derek L. Stirewalt, MD, Vivian G. Oehler, MD, Thomas O'Hare, PhD, Michael W. Deininger

Blood (2015) 126 (23): 14.

https://doi.org/10.1182/blood.V126.23.14.14

Published: 2015

Journal Articles

Transition of Chronic Myeloid Leukemia to Chronic Myelomonocytic Leukemia As a Tool to Observe Development of Chronic Myelomonocytic Leukemia

Jamshid S Khorashad, MD PhD, Srinivas K Tantravahi, Dongqing Yan, PhD, Anna M. Eiring, PhD, Hannah M. Redwine, Amber D. Bowler, Kevin C. Gantz, Keith M Gligorich, PhD, Anthony D Pomicter, MS, Todd W Kelley, MD, Thomas O'Hare, PhD, Michael W Deininger, MD PhD

Blood (2015) 126 (23): 5223.

https://doi.org/10.1182/blood.V126.23.5223.5223

Published: 2015

Journal Articles

Design, Optimization, and Pre-Clinical Evaluation of Direct, Mechanism-Based STAT3 Inhibitors for Treating Myeloid Disorders

William L. Heaton, M.S., Anna M. Eiring, PhD, Nadeem A. Vellore, PhD, Diana Resetca, B.S., Sina Haftchenary, PhD, David Rosa, PhD, Ahmed M. Ali, Anna V. Senina, M.S., Anthony D. Pomicter, M.S., Brent D.G. Page, PhD, Ira L. Kraft, B.S., Kimberly R. Reynolds, M.S., Derek J. Wilson, PhD, Riccardo Baron, PhD, Thomas O'Hare, PhD, Patrick T. Gunning, PhD, Michael W. Deininger

Blood (2014) 124 (21): 4816.

https://doi.org/10.1182/blood.V124.21.4816.4816

Published: 2014

Journal Articles

Next Generation Sequencing to Delineate the Mutational Landscape of Chronic Myelomonocytic Leukemia (CMML): Novel Disease Genes and Correlations with Survival

Clinton C. Mason, PhD, Jamshid S. Khorashad, MD PhD, Srinivas K. Tantravahi, MD, Todd W. Kelley, MD, Anthony D. Pomicter, M.S., Anthony J. Iovino, Kimberly R. Reynolds, M.S., Anna M. Eiring, PhD, Matthew S. Zabriskie, BS, Zev Kronenberg, Jeffrey W. Tyner, Brian Dalley, PhD, Kim-Hien T. Dao, DO,PhD, Thomas O'Hare, PhD, Mark Yandell, PhD, Brian J. Druker, Jason R. Gotlib, MD, Michael W. Deininger

Blood (2014) 124 (21): 4637.

https://doi.org/10.1182/blood.V124.21.4637.4637

Published: 2014

Journal Articles

Limited Efficacy of BMS-911543 in a Murine Model of JAK2 V617F Myeloproliferative Neoplasm

Anthony D. Pomicter, M.S., Anna M. Eiring, PhD, Anna V. Senina, M.S., James E Marvin, M.S., Josef T. Prchal, MD, Thomas O'Hare, Michael W. Deininger

Blood (2014) 124 (21): 5572.

https://doi.org/10.1182/blood.V124.21.5572.5572

Published: 2014

Journal Articles

Autocrine TNF-α Signaling in Hematopoietic Stem Cells Promotes Myeloproliferative Disease Progression through Activation of TNFR2

William L. Heaton, M.S., Anna V. Senina, M.S., Anthony D. Pomicter, M.S., James E Marvin, M.S., Sabina Swierczek, PhD, Anna M. Eiring, PhD, Josef T. Prchal, MD, Thomas O'Hare, Michael W. Deininger

Blood (2014) 124 (21): 1888.

https://doi.org/10.1182/blood.V124.21.1888.1888

Published: 2014

Journal Articles

The Tumor Suppressors, MS4A3 and G0S2, Are Downregulated in CML Cells with BCR-ABL1 Kinase-Independent Resistance

Anna M. Eiring, PhD, Anupriya Agarwal, Jamshid S. Khorashad, MD PhD, Clinton C. Mason, PhD, David J. Anderson, MBA, Fan Yu, MD, PhD, Hannah M. Redwine, Kevin C. Gantz, Kimberly R. Reynolds, M.S., Shannon K. McWeeney, Brian J. Druker, Thomas O'Hare, Michael W. Deininger

Blood (2014) 124 (21): 1786.

https://doi.org/10.1182/blood.V124.21.1786.1786

Published: 2014

Journal Articles

Direct Contact With Bone Marrow Stromal Cells Protects CML Progenitors From Imatinib Through Cytoplasmic Stabilization Of β-Catenin

Anna M. Eiring, PhD, David J. Anderson, MBA, Tian Y. Zhang, MD, PhD, Ira L. Kraft, BS, Kimberly R. Reynolds, MS, Anthony D. Pomicter, MS, Clinton C. Mason, PhD, Thomas O'Hare, Michael W. Deininger, MD, PhD

Blood (2013) 122 (21): 3982.

https://doi.org/10.1182/blood.V122.21.3982.3982

Published: 2013

Journal Articles

An Unbiased shRNA Library Screen Identifies Nucleocytoplasmic Transport As a Potential Target For Treatment Of Chronic Myeloid Leukemia

Jamshid Sorouri Khorashad, MD, PhD, FRCPath, Clinton C. Mason, PhD, Ira L. Kraft, BS, Kimberly R. Reynolds, MS, Anthony D. Pomicter, MS, Anna M. Eiring, PhD, Matthew S. Zabriskie, Anthony J Iovino, William Heaton, Srinivas K. Tantravahi, MBBS, MRCP, Michael Kauffman, MD, PhD, Sharon Schacham, PhD, MBA, Alex Chenchik, PhD, Kyle Bonneau, PhD, Thomas O'Hare, Michael W. Deininger, MD, PhD

Blood (2013) 122 (21): 2707.

https://doi.org/10.1182/blood.V122.21.2707.2707

Published: 2013

Journal Articles

BP5-087, a Novel STAT3 Inhibitor, Combines With BCR-ABL1 Inhibition To Overcome Kinase-Independent Resistance In Chronic Myeloid Leukemia

Anna M. Eiring, PhD, Ira L. Kraft, BS, Brent D.G. Page, PhD, Tian Y. Zhang, MD, PhD, Jamshid S. Khorashad, MD, PhD, FRCPath, Nadeem A. Vellore, PhD, Kimberly R. Reynolds, MS, Anthony D. Pomicter, MS, Anna V. Senina, MS, Matthew S. Zabriskie, BS, Shazia Ahmad, Clinton C. Mason, PhD, Richard Moriggl, PhD, Riccardo Baron, PhD, Thomas O'Hare, Patrick T. Gunning, PhD, Michael W. Deininger

Blood (2013) 122 (21): 854.

https://doi.org/10.1182/blood.V122.21.854.854

Published: 2013

NARROW

NF-κB-Dependent Activation of the Proteasome Components, PSMD1 and PSMD3, As a Mechanism of Resistance to Imatinib

Retrospective Study of Incidence and Survival for Patients with Hematologic Malignancies Residing at the U.S./Mexico Border

Combining Dasatinib and AC220 Reduces Stroma-Based pSTAT5Y694 in FLT3-ITD+ AML and Overcomes FLT3 TKI Resistance

Inhibition of Nucleocytoplasmic Export Enhances Selective Elimination of Leukemic Stem Cells in Chronic Myeloid Leukemia

Selective Inhibition of Nucleocytoplasmic Transport Overcomes Ruxolitinib Resistance in Myelofibrosis

Loss of G0S2 in Kinase-Independent TKI Resistance and Blastic Transformation of CML

A Novel JAK2 Mutation Confers Cytokine-Independence in the Absence of a Type I Dimeric Cytokine Receptor

Stroma-Based Activation of pSTAT3 Y705 Confers Resistance to FLT3 Inhibitors in FLT3 ITD-Positive AML

Selective Inhibition of Nuclear Cytoplasmic Transport As a New Treatment Paradigm in Myelofibrosis

MS4A3: A New Player in Leukemic Stem Cell Survival in Chronic Myeloid Leukemia

MS4A3 Improves Imatinib Response and Survival in BCR-ABL1 Primary TKI Resistance and in Blastic Transformation of Chronic Myeloid Leukemia

Transition of Chronic Myeloid Leukemia to Chronic Myelomonocytic Leukemia As a Tool to Observe Development of Chronic Myelomonocytic Leukemia

Design, Optimization, and Pre-Clinical Evaluation of Direct, Mechanism-Based STAT3 Inhibitors for Treating Myeloid Disorders

Next Generation Sequencing to Delineate the Mutational Landscape of Chronic Myelomonocytic Leukemia (CMML): Novel Disease Genes and Correlations with Survival

Limited Efficacy of BMS-911543 in a Murine Model of JAK2 V617F Myeloproliferative Neoplasm

Autocrine TNF-α Signaling in Hematopoietic Stem Cells Promotes Myeloproliferative Disease Progression through Activation of TNFR2

The Tumor Suppressors, MS4A3 and G0S2, Are Downregulated in CML Cells with BCR-ABL1 Kinase-Independent Resistance

Direct Contact With Bone Marrow Stromal Cells Protects CML Progenitors From Imatinib Through Cytoplasmic Stabilization Of β-Catenin

An Unbiased shRNA Library Screen Identifies Nucleocytoplasmic Transport As a Potential Target For Treatment Of Chronic Myeloid Leukemia

BP5-087, a Novel STAT3 Inhibitor, Combines With BCR-ABL1 Inhibition To Overcome Kinase-Independent Resistance In Chronic Myeloid Leukemia

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American Society of Hematology

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American Society of Hematology

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