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Antonia Lopez-Girona, Ph.D.
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Journal Articles

The Novel mTOR Kinase Inhibitor CC-223 Demonstrates Significant Activity In In Vitro Models Of Multiple Myeloma (MM), Both As a Single Agent and In Combination With The Approved Agents, Dexamethasone, Lenalidomide and Pomalidomide

Emily Rychak, Ph.D., Derek Mendy, B.S., Karen Miller, B.S., Jim Leisten, B.S., Rama Krishna Narla, Ph.D., Heather K Raymon, Ph.D., Rajesh Chopra, M.D., Ph.D., Antonia Lopez-Girona, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 3160.
https://doi.org/10.1182/blood.V122.21.3160.3160
Published: 2013
Journal Articles

Lenalidomide Inhibits Proliferation Of Chronic Lymphocytic Leukemia Cells Via a Cereblon/p21 WAF1/Cip1 -Dependent Mechanism

Jessie-Farah Fecteau, Ph.D., Laura G Corral, Diahnn Futalan, Svetlana Gaidarova, MS, Ila Bharati, BS, Brian Cathers, PhD, Emanuela M. Ghia, PhD, Maria Schwaederlé, PharmaD, Antonia Lopez-Girona, Ph.D., Davorka Messmer, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4139.
https://doi.org/10.1182/blood.V122.21.4139.4139
Published: 2013
Journal Articles

Targeting the Wnt/β-Catenin Signaling Pathway and CD44-Mediated Adhesion As a Rational Approach to Overcome Lenalidomide Resistance in Multiple Myeloma

Chad C. Bjorklund, Ph.D., Sharon Lea Aukerman, PhD, Antonia Lopez-Girona, Ph.D., Mohamad Hussein, MD, Rajesh Chopra, PhD, Isere Kuiatse, Ph.D., Deborah J. Kuhn, Ph.D., Caimiao Wei, PhD, Robert Z. Orlowski, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 928.
https://doi.org/10.1182/blood.V118.21.928.928
Published: 2011
Journal Articles

Direct Binding with Cereblon Mediates the Antiproliferative and Immunomodulatory Action of Lenalidomide and Pomalidomide

Antonia Lopez-Girona, Ph.D., Derek Mendy, Karen Miller, Anita K Gandhi, Jian Kang, Gilles Carmel, Mahan Abbasian, Afshin Mahmoudi, Pilgrim Jackson, Brian Cathers, Emily Rychak, Normand Richard, Helen A Brady, Peter H Schafer, Jilly F Evans, Tom O Daniel, Rajesh Chopra
Journal: Blood
Blood (2011) 118 (21): 738.
https://doi.org/10.1182/blood.V118.21.738.738
Published: 2011