1-20 of 25
Jian Kang
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

CD58 Could be As a Leukemic Marker in Relapsed/Refractory B-ALL Patients after Multiline Therapies

Xinjian Yu, Pan Li, Heyuan Feng, Jian Kang, Yafeng Li, Xichang Zheng, Tong Wu, Shuangyou Liu
Journal: Blood
Blood (2022) 140 (Supplement 1): 1043–1044.
https://doi.org/10.1182/blood-2022-164946
Published: 2022
Journal Articles

CC-92480 Enhances Cell-Autonomous Cytotoxicity through Blockade of G 2 /M Transition When Combined with Bortezomib/Dexamethasone in Pre-Clinical Multiple Myeloma

Chad C Bjorklund, Michael Amatangelo, Jian Kang, Hsiling Chiu, Archana Mukhopadhyay, Krista Wollerman, Michael Pourdehnad, Patrick Hagner, Anjan Thakurta
Journal: Blood
Blood (2021) 138 (Supplement 1): 2669.
https://doi.org/10.1182/blood-2021-153907
Published: 2021
Journal Articles

Pre-Clinical and Clinical Immunomodulatory Effects of Pomalidomide or CC-92480 in Combination with Bortezomib in Multiple Myeloma

Chad C Bjorklund, Michael Amatangelo, Hsiling Chiu, Jian Kang, Tiziana Civardi, Jessica Katz, Paulo Maciag, Patrick Hagner, Michael Pourdehnad, Nizar J. Bahlis, Paul G. Richardson, Anjan Thakurta
Journal: Blood
Blood (2021) 138 (Supplement 1): 1613.
https://doi.org/10.1182/blood-2021-153994
Published: 2021
Journal Articles

Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death

Ana Domostegui, Suresh Peddigari, Carol A. Mercer, Flavia Iannizzotto, Marta L. Rodriguez, Marta Garcia-Cajide, Virginia Amador, Sarah T. Diepstraten, Gemma L. Kelly, Ramón Salazar, Sara C. Kozma, Eric P. Kusnadi, Jian Kang, Antonio Gentilella, Richard B. Pearson, George Thomas, Joffrey Pelletier
Journal: Blood
Blood (2021) 137 (24): 3351–3364.
https://doi.org/10.1182/blood.2020007452
Published: 2021
Includes: Supplemental data
Journal Articles

Preclinical and Translational Support for Clinical Development of Iberdomide in Combination with Proteasome Inhibitors: Mechanism of Synergy in Clinical Trial CC-220-MM-001

Michael Amatangelo, Chad Bjorklund, Jian Kang, Archana Mukhopadhyay, María Dolores Jiménez Nuñez, Lilly Wong, William Pierceall, Sagar Lonial, MD FACP, Niels W.C.J. van de Donk, Rakesh Popat, Sundar Jagannath, MD, Jeffrey Zonder, Monique C. Minnema, Albert Oriol, Jeremy Larsen, Ashraf Z. Badros, MD, Paula Rodriguez-Otero, MD PhD, Pieter Sonneveld, MD PhD, Tuong Vi Nguyen, Kevin Hong, April Sorrell, Anjan Thakurta
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-137710
Published: 2020
Journal Articles

The Quick Antigen Identification By Tissue Flow Cytometry for CAR-T Therapy in Relapsed/Refractory B-Cell Malignancies without Bone Marrow Involvement or Serous Cavity Effusions

Xinjian Yu, Pan Li, Heyuan Feng, Jian Kang, Xichang Zheng, Yunmei Zhang, Wenhong Yang, Tong Wu, MD, Shuangyou Liu
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–12.
https://doi.org/10.1182/blood-2020-139437
Published: 2020
Journal Articles

CD22 Gating for Flow Cytometric Analysis in Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia after CD19 CAR-T Therapy

Xinjian Yu, Pan Li, Heyuan Feng, Jian Kang, Xichang Zheng, Yunmei Zhang, Wenhong Yang, Tong Wu, MD, Shuangyou Liu
Journal: Blood
Blood (2020) 136 (Supplement 1): 13.
https://doi.org/10.1182/blood-2020-139341
Published: 2020
Journal Articles

Iberdomide (CC-220) Has Synergistic Anti-Tumor and Immunostimulatory Activity Against Multiple Myeloma in Combination with Both Bortezomib and Dexamethasone, or in Combination with Daratumumab in Vitro

Michael Amatangelo, Chad C. Bjorklund, Jian Kang, Ann Polonskaia, Sridevi Viswanatha, Anjan Thakurta, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1935.
https://doi.org/10.1182/blood-2018-99-113383
Published: 2018
Journal Articles

FOXM1 Is Associated with Development of Therapeutic Resistance in Multiple Myeloma

Michael Amatangelo, PhD, Maria Ortiz, Paola Neri, MD, Fadi Towfic, PhD, Chad Bjorklund, Jian Kang, Erica Sternberg, Nizar J. Bahlis, MD, Matthew Trotter, PhD, Anjan Thakurta, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1261.
https://doi.org/10.1182/blood.V130.Suppl_1.1261.1261
Published: 2017
Journal Articles

CC-220 Is a Potent Cereblon Modulating Agent That Displays Anti-Proliferative, Pro-Apoptotic and Immunomodulatory Activity on Sensitive and Resistant Multiple Myeloma Cell Lines

Chad C Bjorklund, PhD, Jian Kang, Ling Lu, Michael Amatangelo, PhD, Hsiling Chiu, Anita K. Gandhi, PhD, Michael Pourdehnad, MD, Anke Klippel, PhD, Anjan Thakurta, PhD
Journal: Blood
Blood (2016) 128 (22): 1591.
https://doi.org/10.1182/blood.V128.22.1591.1591
Published: 2016
Journal Articles

CC-122 Is a Cereblon Modulating Agent That Is Active in Lenalidomide-Resistant and Lenalidomide/Dexamethasone-Double-Resistant Multiple Myeloma Pre-Clinical Models

Chad C Bjorklund, PhD, Jian Kang, Ling Lu, Michael Amatangelo, PhD, Hsiling Chiu, Patrick Hagner, PhD, Anita K. Gandhi, PhD, Michael Pourdehnad, MD, Anke Klippel, PhD, Anjan Thakurta, PhD
Journal: Blood
Blood (2016) 128 (22): 1592.
https://doi.org/10.1182/blood.V128.22.1592.1592
Published: 2016
Journal Articles

Novel Small Molecule FLT3 Inhibitors for the Treatment of FLT3-ITD AML

Katelyn Melgar, MacKenzie Walker, Jian-kang Jiang, PhD, Kelli Wilson, PhD, James C. Mulloy, PhD, Craig J Thomas, PhD, Daniel T Starczynowski, PhD
Journal: Blood
Blood (2015) 126 (23): 3690.
https://doi.org/10.1182/blood.V126.23.3690.3690
Published: 2015
Journal Articles

CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL

Patrick R. Hagner, Hon-Wah Man, Celia Fontanillo, Maria Wang, Suzana Couto, Mike Breider, Chad Bjorklund, Courtney G. Havens, Gang Lu, Emily Rychak, Heather Raymon, Rama Krishna Narla, Leo Barnes, Gody Khambatta, Hsiling Chiu, Jolanta Kosek, Jian Kang, Michael D. Amantangelo, Michelle Waldman, Antonia Lopez-Girona, Ti Cai, Michael Pourdehnad, Matthew Trotter, Thomas O. Daniel, Peter H. Schafer, Anke Klippel, Anjan Thakurta, Rajesh Chopra, Anita K. Gandhi
Journal: Blood
Blood (2015) 126 (6): 779–789.
https://doi.org/10.1182/blood-2015-02-628669
Published: 2015
Includes: Supplemental data
Journal Articles

IMiDs® Immunomodulatory Agents Regulate Interferon-Stimulated Genes through Cereblon-Mediated Aiolos Destruction in Multiple Myeloma (MM) Cells: Identification of a Novel Mechanism of Action and Pathway for Resistance

Courtney G. Havens, PhD, Chad Bjorklund, PhD, Jian Kang, BS, Maria Ortiz, PhD, Celia Fontanillo, PhD, Michael Amatangelo, PhD, Ling Lu, BS, Paola E. Neri, MD PhD, Antonia Lopez-Girona, PhD, Nizar J. Bahlis, MD, Anjan Thakurta, PhD, Mathew Trotter, MD, Anita K. Gandhi, PhD, Anke Klippel, PhD, Rajesh Chopra, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3432.
https://doi.org/10.1182/blood.V124.21.3432.3432
Published: 2014
Journal Articles

ADAP interactions with talin and kindlin promote platelet integrin αIIbβ3 activation and stable fibrinogen binding

Ana Kasirer-Friede, Jian Kang, Bryan Kahner, Feng Ye, Mark H. Ginsberg, Sanford J. Shattil
Journal: Blood
Blood (2014) 123 (20): 3156–3165.
https://doi.org/10.1182/blood-2013-08-520627
Published: 2014
Includes: Supplemental data
Journal Articles

Integrated phosphoproteomic and metabolomic profiling reveals NPM-ALK–mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma

Scott R. P. McDonnell, Steven R. Hwang, Delphine Rolland, Carlos Murga-Zamalloa, Venkatesha Basrur, Kevin P. Conlon, Damian Fermin, Thomas Wolfe, Alexander Raskind, Chunhai Ruan, Jian-Kang Jiang, Craig J. Thomas, Cory M. Hogaboam, Charles F. Burant, Kojo S. J. Elenitoba-Johnson, Megan S. Lim
Journal: Blood
Blood (2013) 122 (6): 958–968.
https://doi.org/10.1182/blood-2013-01-482026
Published: 2013
Includes: Supplemental data
Journal Articles

Direct Binding with Cereblon Mediates the Antiproliferative and Immunomodulatory Action of Lenalidomide and Pomalidomide

Antonia Lopez-Girona, Ph.D., Derek Mendy, Karen Miller, Anita K Gandhi, Jian Kang, Gilles Carmel, Mahan Abbasian, Afshin Mahmoudi, Pilgrim Jackson, Brian Cathers, Emily Rychak, Normand Richard, Helen A Brady, Peter H Schafer, Jilly F Evans, Tom O Daniel, Rajesh Chopra
Journal: Blood
Blood (2011) 118 (21): 738.
https://doi.org/10.1182/blood.V118.21.738.738
Published: 2011
Journal Articles

ADAPtation of Platelet Integrin αIIbβ3 to Inside-Out Activation Signals

Ana Kasirer-Friede, PhD, Jian Kang, PhD, Bryan N Kahner, PhD, Sanford J. Shattil, MD
Journal: Blood
Blood (2011) 118 (21): 188.
https://doi.org/10.1182/blood.V118.21.188.188
Published: 2011
Journal Articles

CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP

Wei Ju, Meili Zhang, Jian-kang Jiang, Craig J. Thomas, Unsong Oh, Bonita R. Bryant, Jing Chen, Noriko Sato, Yutaka Tagaya, John C. Morris, John E. Janik, Steven Jacobson, Thomas A. Waldmann
Journal: Blood
Blood (2011) 117 (6): 1938–1946.
https://doi.org/10.1182/blood-2010-09-305425
Published: 2011
Includes: Supplemental data
Journal Articles

Anti-Proliferative and Apoptotic Activity of Lenalidomide in Combination with Rituximab in Follicular Lymphoma: An in Vitro and Ex Vivo Analysis in Follicular Lymphoma Cells.

Anita K Gandhi, Jian Kang, Lori Capone, Marianna Shafarenko, PhD, Peter H Schafer
Journal: Blood
Blood (2009) 114 (22): 3723.
https://doi.org/10.1182/blood.V114.22.3723.3723
Published: 2009