1-20 of 46
Atsushi Iwama, MD
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Immunoglobulin Superfamily Member 8 Is Indispensable for Myeloid Leukemia Via Wnt/β-Catenin Signaling Pathway

Koji Jimbo, MD, Takaaki Konuma, MD PhD, Takahiro Ito, PhD, Yaeko Nakajima-Takagi, PhD, Atsushi Iwama, MD PhD, Arinobu Tojo, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 23–24.
https://doi.org/10.1182/blood-2020-136045
Published: 2020
Journal Articles

Efficacy of Tubulin Polymerization Inhibitor in Myelodysplastic Syndrome

Cheng Zhong, Kensuke Kayamori, MD PhD, Shuhei Koide, Daisuke Shinoda, MD, Motohiko Oshima, PhD, Yaeko Nakajima-Takagi, PhD, Yurie Nagai, MD, Naoya Mimura, MD PhD, William Lennox, Josephine Sheedy, BS, MSc, Marla Weetall, PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35.
https://doi.org/10.1182/blood-2020-134754
Published: 2020
Journal Articles

Akt Inhibition Differently Controls PRC2 Components and Synergizes with Dual EZH2/1 Inhibitor in the Treatment of Multiple Myeloma

Mohamed Rizk, BSc, MSc, Ola Rizq, MD PhD, Motohiko Oshima, PhD, Yaeko Nakajima-Takagi, PhD, Shuhei Koide, PhD, Atsunori Saraya, Yusuke Isshiki, MD PhD, Tetsuhiro Chiba, MD PhD, Satoshi Yamazaki, PhD, Anqi Ma, PhD, Jian Jin, PhD, Atsushi Iwama, MD PhD, Naoya Mimura, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4400.
https://doi.org/10.1182/blood-2019-122157
Published: 2019
Journal Articles

Variant Pcgf-PRC1 Regulates Susceptibility of PRC2 Mediated H3K27me3 to Safeguard B Cell Fate of Hematopoietic Stem/Progenitor Cells

Junichiro Takano, MD, Yaeko Nakajima-Takagi, PhD, Shinsuke Ito, PhD, Haruhiko Koseki, MD PhD, Atsushi Iwama, MD PhD, Tomokatsu Ikawa, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3717.
https://doi.org/10.1182/blood-2019-129518
Published: 2019
Journal Articles

Hmga2 Functions As an Oncogene upon the Deletion of Tet2 and Promotes the Pathogenesis of Myelodysplastic Syndrome

Jie Bai, Sho Kubota, PhD, Takako Yokomizo, PhD, Akinori Kanai, PhD, Yuqi Sun, MD, Mihoko Iimori, CLS, Hironori Harada, MD PhD, Naomi Nakagata, PhD, Atsushi Iwama, MD PhD, Goro Sashida, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3782.
https://doi.org/10.1182/blood-2019-127583
Published: 2019
Journal Articles

New Insights into PLZF/Rara Mechanism during APL Onset: EZH2 on the Road

Mathilde Poplineau, Nadine Platet, PhD, Lia N'Guyen, Shuhei Koide, PhD, Julien Vernerey, PhD, Yaeko Nakajima-Takagi, PhD, Motohiko Oshima, PhD, Atsushi Iwama, MD PhD, Estelle Duprez, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3761.
https://doi.org/10.1182/blood-2019-125509
Published: 2019
Journal Articles

The Preclinical Activities of PTC596, a Novel Tubulin Binding Agent That Down-Regulates BMI1, Alone and in Combination with Bortezomib in Multiple Myeloma

Yurie Nagai, MD, Naoya Mimura, MD PhD, Ola Rizq, MD PhD, Yusuke Isshiki, MD PhD, Motohiko Oshima, PhD, Mohamed Rizk, BSc, MSc, Atsunori Saraya, Shuhei Koide, PhD, Yaeko Nakajima-Takagi, PhD, Makiko Miyota, Nagisa Oshima-Hasegawa, MD PhD, Shokichi Tsukamoto, MD PhD, Shio Mitsukawa, MD PhD, Yusuke Takeda, MD PhD, Chikako Ohwada, MD PhD, Masahiro Takeuchi, MD PhD, Tohru Iseki, MD PhD, Chiaki Nakaseko, MD PhD, Josephine Sheedy, BS, MSc, Marla Weetall, PhD, Atsushi Iwama, MD PhD, Emiko Sakaida, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4414.
https://doi.org/10.1182/blood-2019-122350
Published: 2019
Journal Articles

Synergistic Effect of DHODH Inhibitor PTC299 with DNA Demethylating Agent Decitabine in Myelodysplastic Syndromes

Kensuke Kayamori, Cheng Zhong, Daisuke Shinoda, MD, Shuhei Koide, PhD, Motohiko Oshima, PhD, Yaeko Nakajima-Takagi, PhD, Naoya Mimura, MD PhD, Ryoji Ito, Kaoru Tohyama, MD PhD, William Lennox, Marla Weetall, PhD, Josephine Sheedy, BS, MSc, Emiko Sakaida, MD PhD, Koutaro Yokote, MD PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5407.
https://doi.org/10.1182/blood-2019-125200
Published: 2019
Journal Articles

Role of KDM2B and Non-Canonical PRC1.1 As a Tumor Suppressor in T-ALL

Yusuke Isshiki, MD, Yaeko Nakajima-Takagi, PhD, Motohiko Oshima, PhD, Kazumasa Aoyama, PhD, Atsunori Saraya, Emiko Sakaida, MD PhD, Chiaki Nakaseko, MD PhD, Koutaro Yokote, MD PhD, Haruhiko Koseki, PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2597.
https://doi.org/10.1182/blood-2018-99-117831
Published: 2018
Journal Articles

Utx Insufficiency Cooperates with Braf V600E in the Induction of Myeloma in Mice

Ola Rizq, MD PhD, Naoya Mimura, MD PhD, Motohiko Oshima, PhD, Shuji Momose, MD PhD, Yaeko Nakajima-Takagi, PhD, Kazumasa Aoyama, PhD, Atsunori Saraya, Tohru Iseki, MD PhD, Emiko Sakaida, MD PhD, Chiaki Nakaseko, MDPhD, Yutaka Okuno, MD, PhD, Hiroaki Honda, MD PhD, Jun-ichi Tamaru, MDPhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1005.
https://doi.org/10.1182/blood-2018-99-114053
Published: 2018
Journal Articles

Residual Wild-Type Tet2/Tet3 Allele Is the Savior Preventing Mouse Hematopoietic Progenitor Cells from Leukemia Development

Raksha Shrestha, MD, DiMM, Maie Koichiro, MD PhD, Mamiko Sakata-Yanagimoto, MD PhD, Olivier Bernard, Hirotaka Matsui, MD PhD, Yaeko Nakajima-Takagi, PhD, Takayasu Kato, MD PhD, Haruhiko Koseki, PhD, Atsushi Iwama, MD PhD, Shigeru Chiba, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1330.
https://doi.org/10.1182/blood-2018-99-112352
Published: 2018
Journal Articles

Insufficiency of Non-Canonical PRC1 Complex Cooperates with an Activating JAK2 Mutation in the Pathogenesis of Myelofibrosis

Daisuke Shinoda, MD, Yaeko Nakajima-Takagi, PhD, Motohiko Oshima, PhD, Atsunori Saraya, Hironori Harada, MD PhD, Haruhiko Koseki, PhD, Kazuya Shimoda, MD PhD, Goro Sashida, MD PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 100.
https://doi.org/10.1182/blood-2018-99-117741
Published: 2018
Journal Articles

Lineage-Specific RUNX2 Super-Enhancer Activates MYC Via Translocation (6;8) to Promote the Development of Blastic Plasmacytoid Dendritic Cell Neoplasm

Sho Kubota, PhD, Kenji Tokunaga, MD, Tomohiro Umezu, PhD, Takako Yokomizo, PhD, Motohiko Oshima, PhD, Eisaku Iwanaga, MD PhD, Norio Asou, MDPhD, Atsushi Iwama, MD PhD, Kazuma Ohyashiki, MD PhD, Motomi Osato, MD, PhD, Goro Sashida, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 761.
https://doi.org/10.1182/blood-2018-99-110333
Published: 2018
Journal Articles

Anagrelide Inhibits Proliferation and Platelet Generation in Immortalized Megakaryocyte Progenitor Cell Lines Established from Human Induced Pluripotent Stem Cells

Koji Takaishi, MD, Masahiro Takeuchi, MD PhD, Shokichi Tsukamoto, MD PhD, Naoya Takayama, MD PhD, Motohiko Oshima, PhD, Yusuke Isshiki, MD, Kensuke Kayamori, MD, Kenji Kimura, MD, Yutaro Hino, MD, Nagisa Oshima-Hasegawa, MD PhD, Shio Mitsukawa, MD PhD, Yusuke Takeda, MD PhD, Naoya Mimura, MD PhD, Chikako Ohwada, MD PhD, Tohru Iseki, MD PhD, Sou Nakamura, PhD, Koji Eto, MD PhD, Atsushi Iwama, MD PhD, Koutaro Yokote, MD PhD, Chiaki Nakaseko, MDPhD, Emiko Sakaida, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1789.
https://doi.org/10.1182/blood-2018-99-111683
Published: 2018
Journal Articles

Regulation of Mitophagy By O -Linked N -Acetylglucosamine Transferase Is Essential for Hematopoietic Stem Cell Maintenance

Koichi Murakami, MD, Daisuke Kurotaki, PhD, Wataru Kawase, Graduate student, Shunsuke Soma, MD, Yumi Fukuchi, PhD, Hiroyoshi Kunimoto, MD PhD, Ryusuke Yoshimi, MD PhD, Shuhei Koide, PhD, Motohiko Oshima, PhD, Takako Hishiki, PhD, Noriyo Hayakawa, PhD, Tomomi Matsuura, PhD, Minoru Ko, MD PhD, Mayumi Oda, PhD, Kiichi Yanagisawa, Student, Hiroshi Kobayashi, MD PhD, Yoshitoshi Atobe, PhD, Kengo Funakoshi, MD PhD, Atsushi Iwama, MD PhD, Keiyo Takubo, MD PhD, Shinichiro Okamoto, MD PhD, Tomohiko Tamura, MD PhD, Hideaki Nakajima, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 171.
https://doi.org/10.1182/blood-2018-171
Published: 2018
Journal Articles

RUNX3 Promotes the Development of MDS/MPN Overlap Syndrome Via Enhancing Expression of Myc in the Absence of Tet2

Takako Yokomizo, PhD, Daiki Tanaka, Sho Kubota, PhD, Motohiko Oshima, PhD, Yuka Harada, MD PhD, Akinori Kanai, PhD, Atsushi Iwama, MD PhD, Hironori Harada, Motomi Osato, MD PhD, Goro Sashida, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2494.
https://doi.org/10.1182/blood.V130.Suppl_1.2494.2494
Published: 2017
Journal Articles

Identifications of Highly Aggressive Phenotype with SPI1 Overexpression in Pediatric T Cell Acute Lymphoblastic Leukemia/Lymphoma

Masafumi Seki, MD PhD, Shunsuke Kimura, MD, Kenichi Yoshida, MD PhD, Tomoya Isobe, MD, Hiroo Ueno, MD, Hiromichi Suzuki, MD PhD, Yusuke Shiozawa, MD, Keisuke Kataoka, MD PhD, Yoichi Fujii, MD, Yuichi Shiraishi, PhD, Kenichi Chiba, BA, Hiroko Tanaka, BA, Masatoshi Takagi, MD PhD, Atsushi Iwama, MD PhD, Kentaro Oki, MDPhD, Motohiro Kato, MD PhD, Katsuyoshi Koh, MD, Ryoji Hanada, MD, Hiroshi Moritake, MD PhD, Ryoji Kobayashi, MD PhD, Takao Deguchi, MD PhD, Yoshiko Hashii, MD PhD, Toshihiko Imamura, MD PhD, Atsushi Sato, MD, Keizo Horibe, MD PhD, Nobutaka Kiyokawa, MD PhD, Atsushi Manabe, MD PhD, Akira Ohara, MD PhD, Masashi Sanada, MD PhD, Yasuhide Hayashi, MD PhD, Hiroyuki Mano, MDPhD, Satoru Miyano, PhD, Akira Oka, MD PhD, Seishi Ogawa, MD PhD, Junko Takita, MD PhD
Journal: Blood
Blood (2016) 128 (22): 909.
https://doi.org/10.1182/blood.V128.22.909.909
Published: 2016
Journal Articles

Role of the Polycomb Methyltransferase Ezh1 in Myelodysplastic Syndrome Induced By Ezh2 Insufficiency

Kazumasa Aoyama, PhD, Makiko Mochizuki-Kashio, PhD, Motohiko Oshima, PhD, Shuhei Koide, PhD, Yaeko Nakajima-Takagi, PhD, Mitsutaka Maeda, Goro Sashida, MD PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1968.
https://doi.org/10.1182/blood.V128.22.1968.1968
Published: 2016
Journal Articles

HMGA2 Orchestrates the Tumorgenesis of Myeloproliferative Neoplasms (MPN) in Corporation with JAK2 V617F

Koki Ueda, MD PhD, Kazuhiko Ikeda, MD PhD, Takayuki Ikezoe, MD PhD, Kazuei Ogawa, MD PhD, Yuko Hashimoto, MD PhD, Kayo Harada-Shirado, Hiroshi Ohkawara, MD PhD, Norio Komatsu, MD PhD, Kotaro Shide, MD PhD, Kazuya Shimoda, MD, PhD, Shuhei Koide, PhD, Motohiko Oshima, PhD, Atsushi Iwama, MD PhD, Yasuchika Takeishi, MD PhD
Journal: Blood
Blood (2016) 128 (22): 796.
https://doi.org/10.1182/blood.V128.22.796.796
Published: 2016
Journal Articles

Distinctive Genetic Features of Plasma Cells in POEMS Syndrome

Yuhei Nagao, MD, Naoya Mimura, MD PhD, June Takeda, MD, Motohiko Oshima, PhD, Kenichi Yoshida, MD PhD, Yusuke Shiozawa, MD, Kazumasa Aoyama, PhD, Atsunori Saraya, Shuhei Koide, PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, BA, Hiroko Tanaka, BA, Chika Kawajiri-Manako, MD, Nagisa Hasegawa, MD, Shio Sakai, MD PhD, Yusuke Takeda, MD PhD, Chikako Ohwada, MD PhD, Masahiro Takeuchi, MD PhD, Emiko Sakaida, MD PhD, Tohru Iseki, MD PhD, Sonoko Misawa, MD PhD, Koutaro Yokote, MD PhD, Satoru Miyano, PhD, Osamu Ohara, PhD, Satoshi Kuwabara, MD PhD, Masashi Sanada, MD PhD, Atsushi Iwama, MD PhD, Seishi Ogawa, MD PhD, Chiaki Nakaseko, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4404.
https://doi.org/10.1182/blood.V128.22.4404.4404
Published: 2016