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Journal Articles

Overexpression of MPL Causes Ruxolitinib-Resistance in Myeloproliferative Neoplasms with Calreticulin Frame-Shift Mutations

Shunichiro Yasuda, MD, Satoru Aoyama, MD, Ryoto Yoshimoto, Student, Watanabe Daisuke, MD, Hiroki Akiyama, MD, PhD, Yoshihiro Umezawa, MD, PhD, Ayako Nogami, MD PhD BPharm, Kouhei Yamamoto, Takeo Fujiwara, MD, Yoko Edahiro, MD PhD, Marito Araki, PhD, Norio Komatsu, MD PhD, Tetsuya Fukuda, MD PhD, Ayako Arai, MD PhD, Osamu Miura, MD, PhD, Norihiko Kawamata

Blood (2019) 134 (Supplement_1): 1690.

https://doi.org/10.1182/blood-2019-122652

Published: 2019

Journal Articles

A Nationwide Survey on Chronic Active Epstein-Barr Virus Infection in Japan Based on New Diagnostic Criteria: Clinical Features and Treatment Strategies

Ayako Arai, MD PhD, Ichiro Yonese, Chizuko Sakashita, MD PhD, Ken-Ichi Imadome, PhD, Tohru Kobayashi, MD PhD, Akihisa Sawada, MD PhD, Yoshinori Ito, MD PhD, Shouichi Ohga, MD PhD, Hiroshi Kimura, MD, Ph. D., Shigeyoshi Fujiwara, MD, PhD

Blood (2018) 132 (Supplement 1): 1631.

https://doi.org/10.1182/blood-2018-99-117854

Published: 2018

Journal Articles

Tumor Cells from EBV-Positive T- or NK-Cell Neoplasms Induce Differentiation and Activation of Macrophages By Secreting Humoral Factors

Akiho Tsuzura, Mayumi Yoshimori, Kanoko Konno, Ken-Ichi Imadome, PhD, Erika Onozawa, Ryunosuke Ohkawa, PhD, Minoru Tozuka, PhD, Osamu Miura, MD, PhD, Ayako Arai, MD, PhD

Blood (2017) 130 (Supplement 1): 4026.

https://doi.org/10.1182/blood.V130.Suppl_1.4026.4026

Published: 2017

Journal Articles

Identification of Adverse Risk Factors for Survival in Acquired Pure Red Cell Aplasia Receiving Immunosuppressive Therapy By the Japan PRCA2004/2006 Study and Introduction to the New Cohort Study PRCA2016

Blood (2017) 130 (Supplement 1): 4954.

https://doi.org/10.1182/blood.V130.Suppl_1.4954.4954

Published: 2017

Journal Articles

Gene Expression Profiling of Primary Vitreoretinal Lymphoma

Ayako Arai, MD PhD, Hiroshi Takase, MD PhD, Kouhei Yamamoto, MD PhD, Hiroki Akiyama, MD, Manabu Mochizuki, MD PhD, Osamu Miura, MD PhD

Blood (2015) 126 (23): 1239.

https://doi.org/10.1182/blood.V126.23.1239.1239

Published: 2015

Journal Articles

Systemic Following Intravitreal MTX Administration Prevents CNS Infiltration of Primary Intraocular Lymphoma

Hiroki Akiyama, MD, Hiroshi Takase, MDPhD, Fumito Kubo, MD, Tohru Miki, MD PhD, Masahide Yamamoto, MD PhD, Makoto Tomita, PhD, Manabu Mochizuki, MDPhD, Osamu Miura, MD PhD, Ayako Arai, MD PhD

Blood (2014) 124 (21): 3053.

https://doi.org/10.1182/blood.V124.21.3053.3053

Published: 2014

Journal Articles

STAT3 Is Activated By EBV in T or NK Cells Leading to Development of EBV-T/NK-Lymphoproliferative Disorders

Honami Komatsu, Ken-Ichi Imadome, PhD, Haruna Shibayama, Tomotaka Yada, Momoko Yamada, Kouhei Yamamoto, MDPhD, Takatoshi Koyama, MD PhD, Shigeyoshi Fujiwara, MD PhD, Osamu Miura, MD PhD, Ayako Arai, MD PhD

Blood (2014) 124 (21): 3026.

https://doi.org/10.1182/blood.V124.21.3026.3026

Published: 2014

Journal Articles

Epstein–Barr Virus Induces Activation-Induced Cytidine Deaminase Expression in T or NK Cells Leading to Mutagenesis and Development of Lymphoma

Ayako Arai, MD, PhD, Masato Horino, Ken-Ichi Imadome, PhD, Kohsuke Imai, MD, PhD, Honami Komatsu, Ludan Wang, MD, Go Matsuda, Kasumi Hamazaki, Morito Kurata, MD, PhD, Tetsuya Kurosu, MD, PhD, Shigeyoshi Fujiwara, MD, PhD, Osamu Miura, MD, PhD

Blood (2013) 122 (21): 1765.

https://doi.org/10.1182/blood.V122.21.1765.1765

Published: 2013

Journal Articles

High-Resolution Genomic Copy Number Profiling of Primary Intraocular Lymphomas Using SNP Microarrays

Ludan Wang, MD, Aiko Sato-Otsubo, PhD, Sunao Sugita, MD, PhD, Hiroshi Takase, MD, PhD, Manabu Mochizuki, MD, PhD, Yoshihiko Usui, MD, PhD, Hiroshi Goto, MD, PhD, Osamu Miura, MD, PhD, Seishi Ogawa, MD, PhD, Ayako Arai, MD, PhD

Blood (2011) 118 (21): 1354.

https://doi.org/10.1182/blood.V118.21.1354.1354

Published: 2011

Journal Articles

L-Asparaginase Monotherapy for T- and NK-Cell Type of Chronic Active Epstein-Barr Virus Infection in Adults: A Pilot Study

Ayako Arai, MD, PhD, Minako Jinta, MD, Ken-Ichi Imadome, PhD, Mayumi Yoshimori, Shigeyoshi Fujiwara, MD, PhD, Osamu Miura, MD, PhD

Blood (2011) 118 (21): 4953.

https://doi.org/10.1182/blood.V118.21.4953.4953

Published: 2011

Journal Articles

NF-κB Is Constitutively Activated in EBV-Infected T or NK Cells and Can Be a Molecular Target for EBV-Positive T/NK-Cell Lymphoproliferative Disease Treatment

Ayako Arai, MD, PhD, Mayumi Takahashi, Ken-Ichi Imadome, PhD, Takatoshi Koyama, MD, PhD, Yasunori Saitoh, MD, PhD, Shoji Yamaoka, MD, PhD, Shigeyoshi Fujiwara, MD, PhD, Osamu Miura, MD, PhD

Blood (2010) 116 (21): 1998.

https://doi.org/10.1182/blood.V116.21.1998.1998

Published: 2010

Journal Articles

CD137 Expression Is Enhanced in EBV-Infected T or NK Cells by Viral Protein LMP1 and Mediates Anti-Apoptotic Intracellular Signaling through NF-ĸB Activation.

Ayako Arai, MD, PhD, Ken-ichi Imadome, PhD, Mayumi Takahashi, Koichi Naka, Tetsuya Fukuda, MD, PhD, Shigeyoshi Fujiwara, MD, PhD, Osamu Miura, MD, PhD

Blood (2009) 114 (22): 1929.

https://doi.org/10.1182/blood.V114.22.1929.1929

Published: 2009

Journal Articles

ASK1 Is Activated by Treatment with Arsenic Trioxide through Accumulation of Reactive Oxygen Species and May Suppress Apoptosis through NF-kappaB in Leukemia Cells.

Ayako Arai, MD, PhD, Weihua Yan, Hidenori Ichijo, M.D.,Ph.D., Osamu Miura, M.D.,Ph.D.

Blood (2006) 108 (11): 4394.

https://doi.org/10.1182/blood.V108.11.4394.4394

Published: 2006

Journal Articles

CrkL Mediates SDF-1-Induced Chemotaxis through Ras, Rac, and Erk Activation in Hematopoietic Cells.

Ayako Arai, MD, PhD, Weihua Yan, Mae Aoki, Daisuke Mizuchi, MD, PhD, Tetsuya Kurosu, MD, PhD, Tohru Miki, MD, PhD, Osamu Miura, MD, PhD

Blood (2005) 106 (11): 2290.

https://doi.org/10.1182/blood.V106.11.2290.2290

Published: 2005

NARROW

Overexpression of MPL Causes Ruxolitinib-Resistance in Myeloproliferative Neoplasms with Calreticulin Frame-Shift Mutations

A Nationwide Survey on Chronic Active Epstein-Barr Virus Infection in Japan Based on New Diagnostic Criteria: Clinical Features and Treatment Strategies

Tumor Cells from EBV-Positive T- or NK-Cell Neoplasms Induce Differentiation and Activation of Macrophages By Secreting Humoral Factors

Identification of Adverse Risk Factors for Survival in Acquired Pure Red Cell Aplasia Receiving Immunosuppressive Therapy By the Japan PRCA2004/2006 Study and Introduction to the New Cohort Study PRCA2016

Gene Expression Profiling of Primary Vitreoretinal Lymphoma

Systemic Following Intravitreal MTX Administration Prevents CNS Infiltration of Primary Intraocular Lymphoma

STAT3 Is Activated By EBV in T or NK Cells Leading to Development of EBV-T/NK-Lymphoproliferative Disorders

Epstein–Barr Virus Induces Activation-Induced Cytidine Deaminase Expression in T or NK Cells Leading to Mutagenesis and Development of Lymphoma

High-Resolution Genomic Copy Number Profiling of Primary Intraocular Lymphomas Using SNP Microarrays

L-Asparaginase Monotherapy for T- and NK-Cell Type of Chronic Active Epstein-Barr Virus Infection in Adults: A Pilot Study

NF-κB Is Constitutively Activated in EBV-Infected T or NK Cells and Can Be a Molecular Target for EBV-Positive T/NK-Cell Lymphoproliferative Disease Treatment

CD137 Expression Is Enhanced in EBV-Infected T or NK Cells by Viral Protein LMP1 and Mediates Anti-Apoptotic Intracellular Signaling through NF-ĸB Activation.

ASK1 Is Activated by Treatment with Arsenic Trioxide through Accumulation of Reactive Oxygen Species and May Suppress Apoptosis through NF-kappaB in Leukemia Cells.

CrkL Mediates SDF-1-Induced Chemotaxis through Ras, Rac, and Erk Activation in Hematopoietic Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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