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Journal Articles

TCRαβ/CD19 cell–depleted HLA-haploidentical transplantation to treat pediatric acute leukemia: updated final analysis

Blood (2024) 143 (3): 279–289.

https://doi.org/10.1182/blood.2023021336

Published: 2024

Includes: Supplemental data

Journal Articles

Improved T- and B-Cell Neogenesis in Children with Acute Leukemia Given an Alpha-Beta T-Cell Depleted Haplo-HSCT Combined with the Infusion of Donor T-Cells Genetically Modified with Inducible Caspase 9 Suicide Gene (Rivo-cel)

Marialuigia Catanoso, Mattia Algeri, Enrico Velardi, Emmanuel Clave, Antoine Toubert, Francesca Del Bufalo, Pietro Merli, Daria Pagliara, Barbarella Lucarelli, Federica Galaverna, Marco Rosichini, Valentina Bertaina, Giuseppina Li Pira, Cecilia Surace, Emilia Boccieri, Roberto Carta, Marco Becilli, Francesco Quagliarella, Franco Locatelli

Blood (2023) 142 (Supplement 1): 4924.

https://doi.org/10.1182/blood-2023-190123

Published: 2023

Journal Articles

Updated Analysis on the Outcomes of Children with Acute Leukemia (AL) Receiving an Alpha/Beta T and B-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (TBdepl-haploHSCT)

Blood (2022) 140 (Supplement 1): 1879–1881.

https://doi.org/10.1182/blood-2022-166903

Published: 2022

Journal Articles

Brentuximab in Children, Adolescent and Young Adults with Relapsed/Refractory Anaplastic Large Cell Lymphoma

Luciana Vinti, Pietro Merli, Emanuele Agolini, Francesca Stocchi, Barbarella Lucarelli, Katia Girardi, Mattia Algeri, Emilia Boccieri, Mariachiara Lodi, Marco Becilli, Maria Giuseppina Cefalo

Blood (2022) 140 (Supplement 1): 12141–12142.

https://doi.org/10.1182/blood-2022-170118

Published: 2022

Journal Articles

Outcome of children with acute leukemia given HLA-haploidentical HSCT after αβ T-cell and B-cell depletion

Blood (2017) 130 (5): 677–685.

https://doi.org/10.1182/blood-2017-04-779769

Published: 2017

Includes: Supplemental data

Journal Articles

T-Cell Depleted HLA-Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (haplo-HSCT) Followed By Donor Lymphocyte Infusion with T Cells Transduced with the Inducible Caspase 9 (iC9) Suicide Gene in Children with Hematological Malignancies

Barbarella Lucarelli, MD, Alice Bertaina, MD PhD, Pietro Merli, MD, Concetta Quintarelli, PhD, Daniela Pende, MD, Michela Falco, PhD, Maria Giuseppina Cefalo, MD, Giuseppina Li Pira, PhD, Ignazio Caruana, PhD, Letizia Pomponia Brescia, MD, Luisa Strocchio, MD, Giuseppe Maria Milano, MD, Valentina Bertaina, PhD, Matilde Sinibaldi, PhD, Mattia Algeri, MD, Lorenzo Moretta, MD, Joanna Stanson, Annemarie Moseley, MD PhD, Franco Locatelli, MD

Blood (2016) 128 (22): 4683.

https://doi.org/10.1182/blood.V128.22.4683.4683

Published: 2016

Journal Articles

Clinical Outcome and Immune Recovery after Adoptive Infusion of BPX-501 Cells (donor T cells transduced with iC9 suicide gene) in Children with Hemoglobinopathies and Diamond-Blackfan Anemia Given α/β T-Cell Depleted HLA-Haploidentical Stem Cell Transplantation (HSCT)

Alice Bertaina, MDPhD, Pietro Merli, MD, Daria Pagliara, MD, Giuseppina Li Pira, PhD, Biagio De Angelis, PhD, Letizia Pomponia Brescia, MD, Luisa Strocchio, MD, Francesca Del Bufalo, MD, Mauro Montanari, MD, Barbarella Lucarelli, MD, Mattia Algeri, MD, Martha French, PhD, Annemarie Moseley, MDPhD, Franco Locatelli, MD

Blood (2016) 128 (22): 2286.

https://doi.org/10.1182/blood.V128.22.2286.2286

Published: 2016

Journal Articles

Outcome of Children with Primary Immune-Deficiencies (PIDs) Enrolled in a Phase I-II Trial Based on the Infusion of BPX-501 Donor T Cells Genetically Modified with a Novel Suicide Gene (inducible Caspase 9, iC9) after T-Cell Depleted HLA-Haploidentical Allogeneic Stem Cell Transplantation (haplo-HSCT)

Neena Kapoor, MD, Alice Bertaina, MD PhD, Pietro Merli, MD, Swati Naik, MD, Waseem Qasim, MBBS PhD, Mary Slatter, MD, Reem Elfeky, MD, Barbarella Lucarelli, MD, Monika Smogorzewska, PhD, Giuseppina Li Pira, PhD, Valentina Bertaina, PhD, Annemarie Moseley, MD PhD, Franco Locatelli, MD

Blood (2016) 128 (22): 72.

https://doi.org/10.1182/blood.V128.22.72.72

Published: 2016

Journal Articles

Clinical Outcome after Adoptive Infusion of BPX-501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Results of a Phase I-II Trial

Franco Locatelli, Prof, MD PhD, Pietro Merli, MD, Giuseppina Li Pira, PhD, Valentina Bertaina, PhD, Barbarella Lucarelli, MD, Letizia Pomponia Brescia, MD, Mauro Montanari, MD, Daniela Pende, MD, Michela Falco, PhD, Daria Pagliara, MD, Maria Giuseppina Cefalo, MD, Alessandro Moretta, MD, Concetta Quintarelli, PhD, Brigitte Strahm, MD, Waseem Qasim, MBBS PhD, Mary Slatter, Lorenzo Moretta, MD, Annemarie Moseley, MDPhD, Alice Bertaina, MDPhD

Blood (2015) 126 (23): 1931.

https://doi.org/10.1182/blood.V126.23.1931.1931

Published: 2015

Journal Articles

Children with Acute Leukemia Given Hematopoietic Stem Cell Transplantation (HSCT) from an HLA-Compatible Sibling, or an Unrelated Donor (UD) or an HLA-Haploidentical Relative after Alpha/Beta T-Cell Depletion Have a Comparable Outcome

Alice Bertaina, MDPhD, Barbarella Lucarelli, MD, Riccardo Masetti, MD, Pietro Merli, MD, Roberto Rondelli, MD, Giuseppina Li Pira, PhD, Marco Andreani, PhD, Lavinia Grapulin, MD, Daniela Pende, MD, Michela Falco, PhD, Maria Rita Pinto, MD, Valentina Bertaina, PhD, Maria Teresa Romano, MD, Stefano Ceccarelli, MD, Letizia Pomponia Brescia, MD, Daria Pagliara, MD, Alessandro Moretta, MD, Lorenzo Moretta, MD, Franco Locatelli, Prof, MD PhD

Blood (2015) 126 (23): 195.

https://doi.org/10.1182/blood.V126.23.195.195

Published: 2015

Journal Articles

BPX-501 Cells (donor T cells transduced with iC9 suicide gene) Are Able to Clear Life-Threatening Viral Infections in Children with Primary Immune Deficiencies Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT)

Barbarella Lucarelli, MD, Pietro Merli, MD, Alice Bertaina, MDPhD, Matilde Sinibaldi, PhD, Stefania Gaspari, MD, Luisa Strocchio, MD, Angela Pitisci, PhD, Giuseppina Li Pira, PhD, Giuseppe Maria Milano, MD, Annemarie Moseley, MDPhD, Concetta Quintarelli, PhD, Franco Locatelli, Prof, MD PhD

Blood (2015) 126 (23): 4299.

https://doi.org/10.1182/blood.V126.23.4299.4299

Published: 2015

Journal Articles

Immune Reconstitution after Adoptive Infusion of BPX501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Phenotypic and Functional Results of a Phase I-II Trial

Pietro Merli, MD, Giuseppina Li Pira, PhD, Valentina Bertaina, PhD, Matilde Sinibaldi, PhD, Barbarella Lucarelli, MD, Letizia Pomponia Brescia, MD, Giuseppe Palumbo, MD, Giuseppe Maria Milano, MD, Maria Teresa Romano, MD, Valentina Cirillo, PhD, Luisa Strocchio, MD, Irma Airoldi, PhD, Luciana Vinti, MD, Concetta Quintarelli, PhD, Lorenzo Moretta, MD, Annemarie Moseley, MDPhD, Alice Bertaina, MDPhD, Franco Locatelli, Prof, MD PhD

Blood (2015) 126 (23): 3093.

https://doi.org/10.1182/blood.V126.23.3093.3093

Published: 2015

Journal Articles

γδ T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-αβ + /CD19 + lymphocytes

Irma Airoldi, Alice Bertaina, Ignazia Prigione, Alessia Zorzoli, Daria Pagliara, Claudia Cocco, Raffaella Meazza, Fabrizio Loiacono, Barbarella Lucarelli, Maria Ester Bernardo, Giulia Barbarito, Daniela Pende, Alessandro Moretta, Vito Pistoia, Lorenzo Moretta, Franco Locatelli

Blood (2015) 125 (15): 2349–2358.

https://doi.org/10.1182/blood-2014-09-599423

Published: 2015

Includes: Supplemental data

Journal Articles

HLA-haploidentical stem cell transplantation after removal of αβ + T and B cells in children with nonmalignant disorders

Blood (2014) 124 (5): 822–826.

https://doi.org/10.1182/blood-2014-03-563817

Published: 2014

Journal Articles

Immune Cell Phenotype and Function After Treatment With Blinatumomab For Childhood Relapsed B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

Alice Bertaina, MD, Perla Filippini, BSc MSc, Valentina Bertaina, BSc, Pharm, Barbarella Lucarelli, MD, Aurelie Bauquet, PhD, Gerhard Zugmaier, MD, Franco Locatelli, Sergio Rutella, MD PhD

Blood (2013) 122 (21): 2668.

https://doi.org/10.1182/blood.V122.21.2668.2668

Published: 2013

Journal Articles

Removal Of Alpha/Beta+ T Cells and Of CD19+ B Cells From The Graft Translates Into Rapid Engraftment, Absence Of Visceral Graft-Versus-Host Disease and Low Transplant-Related Mortality In Children With Acute Leukemia Given HLA-Haploidentical Hematopoietic Stem Cell Transplantation

Blood (2013) 122 (21): 157.

https://doi.org/10.1182/blood.V122.21.157.157

Published: 2013

Journal Articles

Interleukin-10 Anergized Donor T Cell Infusion Improves Immune Reconstitution without Severe Graft-Versus-Host-Disease After Haploidentical Hematopoietic Stem Cell Transplantation.

Rosa Bacchetta, MD, Claudia Sartirana, Barbarella Lucarelli, Patrick Miqueu, Maria Teresa Lupo Stanghellini, MD, Raffaella Greco, M.D., Andrea Velardi, Franco Aversa, Massimo F Martelli, Silvia Gregori, Elisabetta Zappone, Katharina Fleischhauer, Massimo Bernardi, MD, Jacopo Peccatori, MD, Fabio Ciceri, MD, Maria Grazia Roncarolo, MD, Prof.

Blood (2009) 114 (22): 45.

https://doi.org/10.1182/blood.V114.22.45.45

Published: 2009

Journal Articles

Functional Analysis and Gene Expression Profile of Umbilical Cord Blood Regulatory T Cells.

Giovanni Fernando Torelli, Roberta Maggio, Nadia Peragine, Sabina Chiaretti, Maria Stefania De Propris, Maria Screnci, Barbarella Lucarelli, Maria Grazia Mascolo, Anna Paola Iori, Gabriella Girelli, Anna Guarini, Robert Foà

Blood (2009) 114 (22): 4085.

https://doi.org/10.1182/blood.V114.22.4085.4085

Published: 2009

Journal Articles

T Regulatory Cells Obtained from Cord Blood Are Greatly Expandable and Exert Potent Suppressive Function.

Giovanni F. Torelli, MD, PhD, Roberta Maggio, BS, Nadia Peragine, BS, Barbarella Lucarelli, MD, Maria S. De Propris, PhD, Maria Screnci, MD, Simona Salvatori, BS, Anna P. Iori, MD, PhD, Filippo Milano, MD, Veronica Valle, MD, Emilia Iannella, MD, Anna Guarini, PhD, Robert Foa, MD

Blood (2007) 110 (11): 4862.

https://doi.org/10.1182/blood.V110.11.4862.4862

Published: 2007

Journal Articles

New approach for bone marrow transplantation in patients with class 3 thalassemia aged younger than 17 years

Pietro Sodani, David Gaziev, Paola Polchi, Buket Erer, Claudio Giardini, Emanuele Angelucci, Donatella Baronciani, Marco Andreani, Marisa Manna, Sonia Nesci, Barbarella Lucarelli, Reginald A. Clift, Guido Lucarelli

Blood (2004) 104 (4): 1201–1203.

https://doi.org/10.1182/blood-2003-08-2800

Published: 2004

NARROW

TCRαβ/CD19 cell–depleted HLA-haploidentical transplantation to treat pediatric acute leukemia: updated final analysis

Improved T- and B-Cell Neogenesis in Children with Acute Leukemia Given an Alpha-Beta T-Cell Depleted Haplo-HSCT Combined with the Infusion of Donor T-Cells Genetically Modified with Inducible Caspase 9 Suicide Gene (Rivo-cel)

Updated Analysis on the Outcomes of Children with Acute Leukemia (AL) Receiving an Alpha/Beta T and B-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (TBdepl-haploHSCT)

Brentuximab in Children, Adolescent and Young Adults with Relapsed/Refractory Anaplastic Large Cell Lymphoma

Outcome of children with acute leukemia given HLA-haploidentical HSCT after αβ T-cell and B-cell depletion

T-Cell Depleted HLA-Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (haplo-HSCT) Followed By Donor Lymphocyte Infusion with T Cells Transduced with the Inducible Caspase 9 (iC9) Suicide Gene in Children with Hematological Malignancies

Clinical Outcome and Immune Recovery after Adoptive Infusion of BPX-501 Cells (donor T cells transduced with iC9 suicide gene) in Children with Hemoglobinopathies and Diamond-Blackfan Anemia Given α/β T-Cell Depleted HLA-Haploidentical Stem Cell Transplantation (HSCT)

Clinical Outcome after Adoptive Infusion of BPX-501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Results of a Phase I-II Trial

Children with Acute Leukemia Given Hematopoietic Stem Cell Transplantation (HSCT) from an HLA-Compatible Sibling, or an Unrelated Donor (UD) or an HLA-Haploidentical Relative after Alpha/Beta T-Cell Depletion Have a Comparable Outcome

BPX-501 Cells (donor T cells transduced with iC9 suicide gene) Are Able to Clear Life-Threatening Viral Infections in Children with Primary Immune Deficiencies Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT)

Immune Reconstitution after Adoptive Infusion of BPX501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Phenotypic and Functional Results of a Phase I-II Trial

γδ T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-αβ + /CD19 + lymphocytes

HLA-haploidentical stem cell transplantation after removal of αβ + T and B cells in children with nonmalignant disorders

Immune Cell Phenotype and Function After Treatment With Blinatumomab For Childhood Relapsed B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

Removal Of Alpha/Beta+ T Cells and Of CD19+ B Cells From The Graft Translates Into Rapid Engraftment, Absence Of Visceral Graft-Versus-Host Disease and Low Transplant-Related Mortality In Children With Acute Leukemia Given HLA-Haploidentical Hematopoietic Stem Cell Transplantation

Interleukin-10 Anergized Donor T Cell Infusion Improves Immune Reconstitution without Severe Graft-Versus-Host-Disease After Haploidentical Hematopoietic Stem Cell Transplantation.

Functional Analysis and Gene Expression Profile of Umbilical Cord Blood Regulatory T Cells.

T Regulatory Cells Obtained from Cord Blood Are Greatly Expandable and Exert Potent Suppressive Function.

New approach for bone marrow transplantation in patients with class 3 thalassemia aged younger than 17 years

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American Society of Hematology

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American Society of Hematology

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