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Journal Articles

Studies of Protein Disulfide Isomerase (PDI) Binding to Platelets and Production of a Murine Monoclonal Antibody (mAb) to Integrin αIIbβ3 That Inhibits PDI Binding and Platelet Aggregation

Lu Wang, Jialing Wang, Jihong Li, Thomas Walz, Barry S. Coller

Blood (2023) 142 (Supplement 1): 1200.

https://doi.org/10.1182/blood-2023-180174

Published: 2023

Journal Articles

In Vitro Effects of the Novel Platelet αIIbβ3 Receptor Antagonist RUC-4 on the Verifynow Assays: Potential for Point-of-Care Monitoring of RUC-4 Therapy

Ohad S. Bentur, MD, Barry S. Coller, MD

Blood (2019) 134 (Supplement_1): 166.

https://doi.org/10.1182/blood-2019-124548

Published: 2019

Journal Articles

Cryo-Electron Microscopy Structure of the aIIbβ3-Abciximab Complex

Dragana Nesic, PhD, Yixiao Zhang, PhD, Aleksandar Spasic, PhD, Jihong Li, MD, Davide Provasi, PhD, Marta Filizola, PhD, Thomas Walz, PhD, Barry S. Coller, MD

Blood (2019) 134 (Supplement_1): 3617.

https://doi.org/10.1182/blood-2019-126985

Published: 2019

Journal Articles

Dominant Role of αIIbβ3 in Platelet Interactions with Polymerizing Cross-Linked Fibrin

Claudia Lorena Buitrago, PhD, Barry S. Coller, MD, Hina Zafar

Blood (2019) 134 (Supplement_1): 1061.

https://doi.org/10.1182/blood-2019-122753

Published: 2019

Journal Articles

The Interaction of Cross-Linked Fibrin Fragment D-Dimer with αIIbβ3 Requires Receptor Activation, Occurs at Sites Other Than the γ-404-411 Sequence, and Contributes to Clot Retraction

Hina Zafar, MS, Jihong Li, MD, Claudia Buitrago, PhD, Dragana Nesic, PhD, Barry S. Coller, MD

Blood (2018) 132 (Supplement 1): 870.

https://doi.org/10.1182/blood-2018-99-116871

Published: 2018

Journal Articles

Pharmacokinetic (PK) and Pharmacodynamic (PD) Studies of RUC-4 Succinate, a Novel αIIbβ3 Pure Antagonist for First Point of Contact Treatment of ST Segment Elevated Myocardial Infarction (STEMI)

Spandana Vootukuri, MS, Jihong Li, MD, Mark Nedelman, MS, MBA, Mariana Babayeva, MD, PhD, Barry S. Coller, MD

Blood (2018) 132 (Supplement 1): 1243.

https://doi.org/10.1182/blood-2018-99-112233

Published: 2018

Journal Articles

Development of a Pure Small Molecule αVβ3 Antagonist

Jihong Li, MD, Yoshiyuki Fukase, PhD, Yi Shang, PhD, Wei Zou, PhD, Ryoma Hara, PhD, Yuta Tanaka, PhD, Rei Okamoto, PhD, Takeshi Yasui, PhD, Takashi Nakahata, PhD, Toshihiro Imaeda, PhD, Kazuyoshi Aso, PhD, Charles Locuson, PhD, Dragana Nesic, PhD, Mark Duggan, PhD, Steven Teitelbaum, MD, Marta Filizola, PhD, Michael Foley, PhD, Barry S. Coller, MD

Blood (2017) 130 (Supplement 1): 548.

https://doi.org/10.1182/blood.V130.Suppl_1.548.548

Published: 2017

Journal Articles

Platelet Activation and Shear- dependent Changes in Filamin a Conformation Downstream of Ligand Binding to αIIbβ3, GPIb and α2β1 Are Reversible in Time, but Those Downstream of Fibrin Binding to αIIbβ3 Are Not

Barry S. Coller, MD, Claudia Buitrago, PhD

Blood (2017) 130 (Supplement 1): 1028.

https://doi.org/10.1182/blood.V130.Suppl_1.1028.1028

Published: 2017

Journal Articles

Use of Bleeding Assessment Tools in the Diagnosis of Von Willebrand Disease: Are We Asking the Right Questions?

Jordan Spradbrow, BSc, Sasha Letourneau, Julie Grabell, CCRP, Yupu Liang, PhD, James Riddel, RN, MS, CPNP, Wilma Hopman, MSc, Victor S. Blanchette, MD, Margaret L. Rand, PhD, Barry S. Coller, MD, Andrew D. Paterson, MD, Paula D. James, MD

Blood (2017) 130 (Supplement 1): 2369.

https://doi.org/10.1182/blood.V130.Suppl_1.2369.2369

Published: 2017

Journal Articles

Blood at 70: its roots in the history of hematology and its birth

Barry S. Coller

Blood (2015) 126 (24): 2548–2560.

https://doi.org/10.1182/blood-2015-09-659581

Published: 2015

Journal Articles

Activated, But Not Unactivated, αIIbβ3 Can Mediate Adhesion to Fibrinogen Lacking the γ Chain Dodecapeptide

Hina Zafar, M.S., Jihong Li, MD, George A David, III, B.A., Barry S. Coller, MD

Blood (2015) 126 (23): 1035.

https://doi.org/10.1182/blood.V126.23.1035.1035

Published: 2015

Journal Articles

Inverse Effects of EDTA on αIIbβ3-Mediated Adhesion to Immobilized Fibrinogen Versus the D98 Plasmin Fragment of Fibrinogen

Hina Zafar, M.S., Jihong Li, MD, George A David, III, B.A., Barry S. Coller, MD

Blood (2015) 126 (23): 1036.

https://doi.org/10.1182/blood.V126.23.1036.1036

Published: 2015

Journal Articles

Planning for the future workforce in hematology research

W. Keith Hoots, Janis L. Abkowitz, Barry S. Coller, Donna M. DiMichele

Blood (2015) 125 (18): 2745–2752.

https://doi.org/10.1182/blood-2015-01-617811

Published: 2015

Journal Articles

αIIbβ3 Variants Defined By Next Generation Sequencing: Implications for Predicting Variants Likely to Cause Glanzmann Thrombasthenia and Alloimmune Disorders

Claudia Lorena Buitrago, PhD#, Augusto Rendon, PhD#~, Ernest Turro, PhD, Yupu Liang, PhD, Ilenia Simeoni, PhD, Ana Negri, PhD, ThromboGenomics Consortium, Marta Filizola, PhD, Willem H. Ouwehand, MDPhDFRCPath FMedSci #, Barry S. Coller, MD#

Blood (2014) 124 (21): 4151.

https://doi.org/10.1182/blood.V124.21.4151.4151

Published: 2014

Journal Articles

Systemic Activation of Platelet-Derived TGF-β1 Leads to Increased Smad2/3 Phosphorylation in Circulating Leukocytes and Platelet-Leukocyte Aggregates in a Mouse Model of Aortic Valve Stenosis

Wei Wang, MD, Nathalie Burg, MD, Spandana Vootukuri, MS, Barry S. Coller, MD

Blood (2014) 124 (21): 2756.

https://doi.org/10.1182/blood.V124.21.2756.2756

Published: 2014

Journal Articles

Three-dimensional reconstruction of intact human integrin αIIbβ3: new implications for activation-dependent ligand binding

Won-Seok Choi, William J. Rice, David L. Stokes, Barry S. Coller

Blood (2013) 122 (26): 4165–4171.

https://doi.org/10.1182/blood-2013-04-499194

Published: 2013

Includes: Supplemental data

Journal Articles

Normal Range Of Bleeding Scores For The ISTH-BAT: Adult and Pediatric Data From The Merging Project

Malak Elbatarny, Shamim Mollah, Julie Grabell, Margaret L. Rand, PhD, Dewi S. Clark, BSc, Andreas Mauer, Pamela A. Christopherson, Robert R. Montgomery, MD, Zimmerman Program Investigators, Barry S. Coller, MD, Paula D. James, MD

Blood (2013) 122 (21): 1107.

https://doi.org/10.1182/blood.V122.21.1107.1107

Published: 2013

Journal Articles

Patients With End Stage Congestive Heart Failure Have Decreased High Molecular Weight Von Willebrand Factor Multimers and Higher Plasma Levels Of Total TGF-β1: Implantation Of a Left Ventricular Assist Devices (LVAD) Exacerbates Both Abnormalities

Jasimuddin Ahamed, PhD, Juan Monteagudo, MD, Mona Kinkhabwala, MD, Mayte Suarez-Farinas, PhD, Arthur Reshad Garan, MD, Barry S. Coller, MD, Donna Mancini, MD

Blood (2013) 122 (21): 1057.

https://doi.org/10.1182/blood.V122.21.1057.1057

Published: 2013

Journal Articles

Changes in Plasma TGF-β1 Levels in a Murine Model of Aortic Stenosis (Surgical Constriction of the Ascending Aorta) in C57Bl/6 (wild-type) Mice and Mice with a Targeted Deletion of Platelet TGF-β1

Wei Wang, MD, Alexander Meyer, Barry S. Coller, MD, Jasimuddin Ahamed, PhD

Blood (2012) 120 (21): 1065.

https://doi.org/10.1182/blood.V120.21.1065.1065

Published: 2012

Journal Articles

Three-Dimensional Reconstruction of Intact Human Integrin α IIb β 3 in a Phospholipid Bilayer Nanodisc

Won-Seok Choi, PhD, Willam J. Rice, PhD, Ana Negri, PhD, Marta Filizola, PhD, David L. Stokes, PhD, Barry S. Coller, MD

Blood (2012) 120 (21): 92.

https://doi.org/10.1182/blood.V120.21.92.92

Published: 2012

NARROW

Studies of Protein Disulfide Isomerase (PDI) Binding to Platelets and Production of a Murine Monoclonal Antibody (mAb) to Integrin αIIbβ3 That Inhibits PDI Binding and Platelet Aggregation

In Vitro Effects of the Novel Platelet αIIbβ3 Receptor Antagonist RUC-4 on the Verifynow Assays: Potential for Point-of-Care Monitoring of RUC-4 Therapy

Cryo-Electron Microscopy Structure of the aIIbβ3-Abciximab Complex

Dominant Role of αIIbβ3 in Platelet Interactions with Polymerizing Cross-Linked Fibrin

The Interaction of Cross-Linked Fibrin Fragment D-Dimer with αIIbβ3 Requires Receptor Activation, Occurs at Sites Other Than the γ-404-411 Sequence, and Contributes to Clot Retraction

Pharmacokinetic (PK) and Pharmacodynamic (PD) Studies of RUC-4 Succinate, a Novel αIIbβ3 Pure Antagonist for First Point of Contact Treatment of ST Segment Elevated Myocardial Infarction (STEMI)

Development of a Pure Small Molecule αVβ3 Antagonist

Platelet Activation and Shear- dependent Changes in Filamin a Conformation Downstream of Ligand Binding to αIIbβ3, GPIb and α2β1 Are Reversible in Time, but Those Downstream of Fibrin Binding to αIIbβ3 Are Not

Use of Bleeding Assessment Tools in the Diagnosis of Von Willebrand Disease: Are We Asking the Right Questions?

Blood at 70: its roots in the history of hematology and its birth

Activated, But Not Unactivated, αIIbβ3 Can Mediate Adhesion to Fibrinogen Lacking the γ Chain Dodecapeptide

Inverse Effects of EDTA on αIIbβ3-Mediated Adhesion to Immobilized Fibrinogen Versus the D98 Plasmin Fragment of Fibrinogen

Planning for the future workforce in hematology research

αIIbβ3 Variants Defined By Next Generation Sequencing: Implications for Predicting Variants Likely to Cause Glanzmann Thrombasthenia and Alloimmune Disorders

Systemic Activation of Platelet-Derived TGF-β1 Leads to Increased Smad2/3 Phosphorylation in Circulating Leukocytes and Platelet-Leukocyte Aggregates in a Mouse Model of Aortic Valve Stenosis

Three-dimensional reconstruction of intact human integrin αIIbβ3: new implications for activation-dependent ligand binding

Normal Range Of Bleeding Scores For The ISTH-BAT: Adult and Pediatric Data From The Merging Project

Patients With End Stage Congestive Heart Failure Have Decreased High Molecular Weight Von Willebrand Factor Multimers and Higher Plasma Levels Of Total TGF-β1: Implantation Of a Left Ventricular Assist Devices (LVAD) Exacerbates Both Abnormalities

Changes in Plasma TGF-β1 Levels in a Murine Model of Aortic Stenosis (Surgical Constriction of the Ascending Aorta) in C57Bl/6 (wild-type) Mice and Mice with a Targeted Deletion of Platelet TGF-β1

Three-Dimensional Reconstruction of Intact Human Integrin α IIb β 3 in a Phospholipid Bilayer Nanodisc

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American Society of Hematology

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American Society of Hematology

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