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Journal Articles

Regulation of Drug Resistance Via the Overexpression of Phopho-RKIP (P-RKIP) in Multiple Myeloma: Dephosphorylation of P-RKIP Reverses Drug Resistance

Devasis Chatterjee, Ph. D, Stavroula Baritaki, PhD, Benjamin Bonavida, PhD

Blood (2017) 130 (Supplement 1): 4971.

https://doi.org/10.1182/blood.V130.Suppl_1.4971.4971

Published: 2017

Journal Articles

High Expression of the Resistant Factor YY1 and Low Expression of the RKIP Chemosensitizing Factor in Multiple Myeloma: Delineation of Several Crosstalk Pathways That Regulate the Expression of These Factors

Stephanie Wottrich, Bachelor of Science, Samantha Kaufhold, Bachelor of Science, Stavroula Baritaki, PhD, Benjamin Bonavida, PhD

Blood (2017) 130 (Supplement 1): 5417.

https://doi.org/10.1182/blood.V130.Suppl_1.5417.5417

Published: 2017

Journal Articles

Yin Yang 1 (YY1) Acting Primarily As an Oncogene and Rarely As a Tumor Suppressor in Distinct Hematological Malignancies: Prognostic and Therapeutic Implications

Samantha Kaufhold, Stephanie Wottrich, Hermes Garban, MD PhD, Massimo Libra, MD Ph.D., Benjamin Bonavida, PhD

Blood (2016) 128 (22): 5122.

https://doi.org/10.1182/blood.V128.22.5122.5122

Published: 2016

Journal Articles

Overexpression of Raf Kinase Inhibitor Protein (RKIP) in Multiple Myeloma and Its Molecular Signature

Anna Shvartsur, Hermes Garban, MD PhD, Benjamin Bonavida, PhD

Blood (2016) 128 (22): 5673.

https://doi.org/10.1182/blood.V128.22.5673.5673

Published: 2016

Journal Articles

KLF4 and YY1 Are Resistant Factors in NHL and Potential Therapeutic Targets: The New Resistant NF-κb/YY1/KLF4/Bcl xL /Mcl-1 Axis

Mayra R Montecillo-Aguado, MsC, Gabriel G Vega, PhDstudent, Hector Mayani, PhD, Sara Huerta-Yepez, PhD, Benjamin Bonavida, PhD, Otoniel Martinez-Maza, PhD, Mario I. Vega, PhD

Blood (2015) 126 (23): 1466.

https://doi.org/10.1182/blood.V126.23.1466.1466

Published: 2015

Journal Articles

Cooperation Between the CD20 Receptor and hIFN-Alpha Receptor in Overriding the Blocked CD20 Cell-Signaling in Rituximab-Resistant B-NHL By the Fusion Protein Anti-CD20-hIFN-Alpha

Gabriel G Vega, PhDstudent, Luz A Franco-Cea, Sara Huerta-Yepez, PhD, Hector Mayani, PhD, Otoniel Martinez-Maza, PhD, Benjamin Bonavida, PhD, Mario I. Vega, PhD

Blood (2015) 126 (23): 1468.

https://doi.org/10.1182/blood.V126.23.1468.1468

Published: 2015

Journal Articles

A Bioinformatics Approach Revealed a Differential Expression of RKIP-Related Genes in Pre-Multiple Myeloma and Multiple Myeloma: Clinical Implications

Anna Shvartsur, Devasis Chatterjee, PhD, Haiming Chen, MD PhD, James Berenson, MD, Hermes Garban, MD PhD, Benjamin Bonavida, PhD

Blood (2015) 126 (23): 5309.

https://doi.org/10.1182/blood.V126.23.5309.5309

Published: 2015

Journal Articles

In silico Tissue-Based Expression Analysis of YY1 and Cancer Stem Cell (CSC) Transcription Factors in Hematological Malignancies: Unraveling New Therapeutic Targets

Samantha Kaufhold, Hermes Garban, MD PhD, Benjamin Bonavida, PhD

Blood (2015) 126 (23): 4814.

https://doi.org/10.1182/blood.V126.23.4814.4814

Published: 2015

Journal Articles

Anti-Myeloma Activity by the Combination of the JAK2 Inhibitor Ruxolitinib with Lenalidomide and Corticosteroids

Haiming Chen, MD, PhD, Eric Sanchez, BA, Mingjie Li, BS, Cathy Wang, BS, Abby Gillespie, BS, Anna Shvartsur, Suzie Vardanyan, MS, Nika M Harutyunyan, Gigi Garzio, George Tang, PhD, Benjamin Bonavida, PhD, James R. Berenson, MD

Blood (2014) 124 (21): 2114.

https://doi.org/10.1182/blood.V124.21.2114.2114

Published: 2014

Journal Articles

Circulating Bcma Binding to Its Ligand BAFF Prevents Normal Antibody Production in Multiple Myeloma Patients

Eric Sanchez, BA, Abigail Gillespie, Nika M Harutyunyan, George Tang, PhD, Jillian Gottlieb, Suzie Vardanyan, MS, Mingjie Li, BS, Claudia Andreu-Vieyra, Michael Ghermezi, Cathy Wang, BS, Joseph Ben-Zvi, Gigi Garzio, Judith Finlay, PhD, Benjamin Bonavida, PhD, Haiming Chen, MD, PhD, James R. Berenson, MD

Blood (2014) 124 (21): 4713.

https://doi.org/10.1182/blood.V124.21.4713.4713

Published: 2014

Journal Articles

Increased M2 Macrophages in Multiple Myeloma Patients with Progressive Disease and Down-Regulated Polarization with the JAK2 Inhibitor Ruxolitinib

Blood (2014) 124 (21): 4106.

https://doi.org/10.1182/blood.V124.21.4106.4106

Published: 2014

Journal Articles

Yin Yang 1 (YY1) Regulates The Transcription Of The Gene Krüppel-Like Factor 4 ( KLF4 ) In Pediatric Burkitt Lymphoma: Clinical Implications

Mario I Vega, PhD, Alberto Valencia-Hipolito, MD/PhD, Miriam Hernandez-Atenogenes, ChB, Gabriel G Vega, MDVZ/PhD, Hector Mayani, PhD, Sara Huerta-Yepez, PhD, Benjamin Bonavida, Ph.D, Otoniel Martinez-Maza, PhD

Blood (2013) 122 (21): 3004.

https://doi.org/10.1182/blood.V122.21.3004.3004

Published: 2013

Journal Articles

Higher TRAF6 and Fbxo 3 Expression Is With Progressive Multiple Myeloma and Blockage Of TRAF6 Inhibits Tumor Growth and Bone Resorption

Mingjie Li, Suzie Vardanyan, Jillian Gottlieb, Cathy Wang, Kevin Delijani, Ran Halleluyan, Joseph Ben-Zvi, Mitchell Song, Eric Sanchez, Benjamin Bonavida, Ph.D, Haiming Chen, MD., Ph.D, James R. Berenson, MD

Blood (2013) 122 (21): 5362.

https://doi.org/10.1182/blood.V122.21.5362.5362

Published: 2013

Journal Articles

Increased M2 Macrophages and Higher Levels Of The Tribble Family Member Trib1 In Monocytes Are Associated With Progressive Disease In Multiple Myeloma (MM) Patients

Haiming Chen, MD., Ph.D, Mingjie Li, Suzie Vardanyan, Jillian Gottlieb, Cathy Wang, Kevin Delijani, Joseph Ben-Zvi, Mitchell Song, Ran Halleluyan, Eric Sanchez, Benjamin Bonavida, PhD, James R. Berenson, MD

Blood (2013) 122 (21): 3127.

https://doi.org/10.1182/blood.V122.21.3127.3127

Published: 2013

Journal Articles

Inhibition of B-NHL Tumor Xenografts Following Treatment with Galiximab (Anti-CD80 mAb) and Potentiation When Combined with Chemotherapy

Mario I Vega, PhD, Hari Hariharan, PhD, Peter Chu, PhD, Tracey Murphy, PhD, Dana Clanton, PhD, Lisa Berquist, PhD, Arturo Molina, PhD, Steffan Ho, PhD, Benjamin Bonavida, Ph.D

Blood (2012) 120 (21): 4873.

https://doi.org/10.1182/blood.V120.21.4873.4873

Published: 2012

Journal Articles

Decreased LIMD1 Gene Expression Is Associated with HIF-1α Over-Expression and Angiogenesis in Multiple Myeloma

Haiming Chen, MD., Ph.D, Jennifer Li, Kevin Delijani, Danielle Rauch, Kevin DeCorso, Andrew Prajogi, Cathy S Wang, Eric Sanchez, Benjamin Bonavida, Ph.D, James R. Berenson, MD

Blood (2012) 120 (21): 1829.

https://doi.org/10.1182/blood.V120.21.1829.1829

Published: 2012

Journal Articles

Anti-Myeloma Effects of the Janus Kinase 2 (JAK2) Inhibitor SAR503 Alone and in Combination Treatment

Haiming Chen, MD., Ph.D, Mingjie Li, Jennifer Li, Kevin Delijani, Danielle Rauch, Kevin DeCorso, Andrew Prajogi, Cathy S Wang, Eric Sanchez, Benjamin Bonavida, Ph.D, James R. Berenson, MD

Blood (2012) 120 (21): 4986.

https://doi.org/10.1182/blood.V120.21.4986.4986

Published: 2012

Journal Articles

Blockage of CGEN-928 Expression Down-Regulates AKT Signaling Pathway and Inhibits Multiple Myeloma (MM) Cell Proliferation

Haiming Chen, Mingjie Li, Jennifer Li, Marissa P Dreyer, Cameryn P Ahles, Tiffany Lee, Joleen T Qiu, Cathy Wang, Eric Sanchez, Benjamin Bonavida, Ph.D, Ofer Levy, Liat Dassa, Gady Cojocaru, Zurit Levine, James R. Berenson, MD

Blood (2011) 118 (21): 5102.

https://doi.org/10.1182/blood.V118.21.5102.5102

Published: 2011

Journal Articles

Frequent Dysregulation of Fc Gamma Receptor IIb (Fc γRIIb) and Immunoreceptor Tyrosine-Based Inhibitory Motif (ITIM) Signaling Occurs in Multiple Myeloma (MM) Patients

Jennifer Li, Andrew Leu, Mingjie Li, Ethan D Hobel, Kevin Delijani, Joleen T Qiu, David Ramirez, Alison C Lam, Cathy Wang, Eric Sanchez, Benjamin Bonavida, Ph.D, Haiming Chen, James R. Berenson, MD

Blood (2011) 118 (21): 2917.

https://doi.org/10.1182/blood.V118.21.2917.2917

Published: 2011

Journal Articles

TRAF6 Dominant Negative Peptides Block Intracellular Signaling Resulting in Anti-Myeloma and Anti-Bone Resorptive Effects in Multiple Myeloma

Mingjie Li, Marissa P Dreyer, Cameryn P Ahles, David Ramirez, Cydney M Nichols, Tiffany Lee, More Song, Cathy S Wang, Eric Sanchez, Haiming Chen, Benjamin Bonavida, Ph.D, James R. Berenson, MD

Blood (2011) 118 (21): 2919.

https://doi.org/10.1182/blood.V118.21.2919.2919

Published: 2011

NARROW

Regulation of Drug Resistance Via the Overexpression of Phopho-RKIP (P-RKIP) in Multiple Myeloma: Dephosphorylation of P-RKIP Reverses Drug Resistance

High Expression of the Resistant Factor YY1 and Low Expression of the RKIP Chemosensitizing Factor in Multiple Myeloma: Delineation of Several Crosstalk Pathways That Regulate the Expression of These Factors

Yin Yang 1 (YY1) Acting Primarily As an Oncogene and Rarely As a Tumor Suppressor in Distinct Hematological Malignancies: Prognostic and Therapeutic Implications

Overexpression of Raf Kinase Inhibitor Protein (RKIP) in Multiple Myeloma and Its Molecular Signature

KLF4 and YY1 Are Resistant Factors in NHL and Potential Therapeutic Targets: The New Resistant NF-κb/YY1/KLF4/Bcl xL /Mcl-1 Axis

Cooperation Between the CD20 Receptor and hIFN-Alpha Receptor in Overriding the Blocked CD20 Cell-Signaling in Rituximab-Resistant B-NHL By the Fusion Protein Anti-CD20-hIFN-Alpha

A Bioinformatics Approach Revealed a Differential Expression of RKIP-Related Genes in Pre-Multiple Myeloma and Multiple Myeloma: Clinical Implications

In silico Tissue-Based Expression Analysis of YY1 and Cancer Stem Cell (CSC) Transcription Factors in Hematological Malignancies: Unraveling New Therapeutic Targets

Anti-Myeloma Activity by the Combination of the JAK2 Inhibitor Ruxolitinib with Lenalidomide and Corticosteroids

Circulating Bcma Binding to Its Ligand BAFF Prevents Normal Antibody Production in Multiple Myeloma Patients

Increased M2 Macrophages in Multiple Myeloma Patients with Progressive Disease and Down-Regulated Polarization with the JAK2 Inhibitor Ruxolitinib

Yin Yang 1 (YY1) Regulates The Transcription Of The Gene Krüppel-Like Factor 4 ( KLF4 ) In Pediatric Burkitt Lymphoma: Clinical Implications

Higher TRAF6 and Fbxo 3 Expression Is With Progressive Multiple Myeloma and Blockage Of TRAF6 Inhibits Tumor Growth and Bone Resorption

Increased M2 Macrophages and Higher Levels Of The Tribble Family Member Trib1 In Monocytes Are Associated With Progressive Disease In Multiple Myeloma (MM) Patients

Inhibition of B-NHL Tumor Xenografts Following Treatment with Galiximab (Anti-CD80 mAb) and Potentiation When Combined with Chemotherapy

Decreased LIMD1 Gene Expression Is Associated with HIF-1α Over-Expression and Angiogenesis in Multiple Myeloma

Anti-Myeloma Effects of the Janus Kinase 2 (JAK2) Inhibitor SAR503 Alone and in Combination Treatment

Blockage of CGEN-928 Expression Down-Regulates AKT Signaling Pathway and Inhibits Multiple Myeloma (MM) Cell Proliferation

Frequent Dysregulation of Fc Gamma Receptor IIb (Fc γRIIb) and Immunoreceptor Tyrosine-Based Inhibitory Motif (ITIM) Signaling Occurs in Multiple Myeloma (MM) Patients

TRAF6 Dominant Negative Peptides Block Intracellular Signaling Resulting in Anti-Myeloma and Anti-Bone Resorptive Effects in Multiple Myeloma

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American Society of Hematology

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American Society of Hematology

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