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Journal Articles

Vaccination with a Personalized Dendritic Cell/AML Fusion Cell Vaccine Following Allogeneic Transplantation in a Phase 1 Clinical Trial

Blood (2020) 136 (Supplement 1): 10.

https://doi.org/10.1182/blood-2020-141634

Published: 2020

Journal Articles

Using an in-Vivo Degron-Based Approach to Interrogate Dependencies of Serially Acquired Mutations - Including DNMT3a-R882 and NPM1c - in Acute Myeloid Leukemia

Andrew A Guirguis, MD PhD, Alexander Tepper, Max Jan, MD PhD, Quinlan Sievers, MD PhD, Benjamin L. Ebert, MDPhD

Blood (2020) 136 (Supplement 1): 12–13.

https://doi.org/10.1182/blood-2020-142566

Published: 2020

Journal Articles

Targeted Sequencing of 7 Genes Can Help Reduce Pathologic Misclassification of MDS

Blood (2020) 136 (Supplement 1): 32–33.

https://doi.org/10.1182/blood-2020-140317

Published: 2020

Journal Articles

A Novel Inflammatory Index Is Sufficient to Identify Hemophagocytic Lymphohistiocytosis in Adult Patients with Hematologic Malignancies

Adi Zoref-Lorenz, MD, Jun Murakami, MD PhD, Liron Hofstetter, MD, Swaminathan P Iyer, MD, Ahmad S. Alotaibi, MD, Peter Miller, MDPhD, Elad Guber, MD, Shiri Weinstein, MD, Joanne Yacobovich, MD MPH, Sarah Nikiforow, MD PhD, Benjamin L. Ebert, MDPhD, Oren Pasvolsky, MD, Pia Raanani, MD, Arnon Nagler, MD, Nancy Berliner, MD, Naval Daver, MD, Martin H Ellis, Michael B. Jordan, MD

Blood (2020) 136 (Supplement 1): 1–2.

https://doi.org/10.1182/blood-2020-143011

Published: 2020

Journal Articles

Congenital X-Linked Myelodysplasia with Tetraploidy Is Associated with De Novo Germline C-Terminal Mutation of SEPT6, a Septin Filament Protein

Raffaele Renella, MD PhD, Katelyn Gagne, BS, Ellen Beauchamp, BA, Thorsten Schlaeger, PhD, Inga Hofmann, MD, Akiko Shimamura, MD PhD, Jonathan Fogel, BSc, Suneet Agarwal, MDPhD, Benjamin L. Ebert, MDPhD, Kyriacos Markianos, Timothy A. Springer, PhD, Mark D. Fleming, MD DPhil, David A. Williams, MD

Blood (2018) 132 (Supplement 1): 644.

https://doi.org/10.1182/blood-2018-99-114682

Published: 2018

Journal Articles

Loss-of-Function Mutations in Dnmt3a and Tet2 Lead to Accelerated Atherosclerosis and Convergent Macrophage Phenotypes in Mice

Philipp J. Rauch, MD, Alexander J. Silver, BA, Jk Gopakumar, BA, Marie McConkey, PhD, Eti Sinha, BS, Maia Fefer, BS, Eugenia Shvartz, BS, Galina Sukhova, PhD, Peter Libby, MD, Benjamin L. Ebert, MDPhD, Siddhartha Jaiswal, MD PhD

Blood (2018) 132 (Supplement 1): 745.

https://doi.org/10.1182/blood-2018-99-118288

Published: 2018

Journal Articles

Bcor Mutations Cooperate with Tet2 Deficiency to Promote RAS Transformation of Mouse Hematopoietic Progenitors

Iman Fares, PhD, Rahul S. Vedula, MD, Shabbir M. Vahanvaty, Christopher S Waters, Marlise R. Luskin, MD, Priti Kumari, M.S., Marie McConkey, PhD, Anne Charles, BS, Kevin Copson, MA, Gregory A. Abel, MDMPH, Richard M. Stone, MD, Benjamin L. Ebert, MDPhD, R. Coleman Lindsley, MD PhD

Blood (2018) 132 (Supplement 1): 888.

https://doi.org/10.1182/blood-2018-99-120096

Published: 2018

Journal Articles

The Role of Clonal Hematopoiesis of Indeterminate Potential (CHIP) in Multiple Myeloma: Immunomodulator Maintenance Post Autologous Stem Cell Transplant (ASCT) Predicts Better Outcome

Blood (2018) 132 (Supplement 1): 749.

https://doi.org/10.1182/blood-2018-99-113059

Published: 2018

Journal Articles

CRISPR-Based Functional Genomics Studies Reveal Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins: Implications for Novel Therapeutics across Diverse Neoplasias

Blood (2018) 132 (Supplement 1): 1367.

https://doi.org/10.1182/blood-2018-99-116232

Published: 2018

Journal Articles

Engineered Bcor Mutations Lead to Acute Lymphoblastic Leukemia of Progenitor B-1 Lymphocyte Origin in a Sensitized Background

Mianmian Yin, PhD, Yang Jo Chung, PhD, R. Coleman Lindsley, MD, PhD, Yeulin Zhu, PhD, Robert L. Walker, PhD, Benjamin L. Ebert, MDPhD, Paul S. Meltzer, MD PhD, Peter D. Aplan, MD

Blood (2018) 132 (Supplement 1): 1331.

https://doi.org/10.1182/blood-2018-99-115388

Published: 2018

Journal Articles

SNP-Array Genome Wide Association Study Meta-Analysis Identifies Innate Immune Susceptibility Loci Associated with Non-Del(5q) Myelodysplastic Syndromes Predisposition

Blood (2018) 132 (Supplement 1): 107.

https://doi.org/10.1182/blood-2018-99-118747

Published: 2018

Journal Articles

Multiplex CRISPR/Cas9-Based Genome Editing of Mouse Hematopoietic Stem Cells Recapitulates Acute Erythroid Leukemia and Identifies Therapeutic Targets

Ilaria Iacobucci, PhD, Elena Varotto, MD, Chunxu Qu, PhD, Laura Janke, DVM, PhD, Aman Seth, PhD, Anang Shelat, PhD, Burgess Freeman, PhD, James Kennedy, Adam S Sperling, MD PhD, R. Coleman Lindsley, MD PhD, Kirsten Dickerson, BS, Debbie Payne-Turner, Sarah M Morris, Nina Ghosn, Benjamin L. Ebert, MDPhD, Charles G. Mullighan, MBBS, MD

Blood (2018) 132 (Supplement 1): 5.

https://doi.org/10.1182/blood-2018-99-118817

Published: 2018

Journal Articles

STAG2 Mutations Alter Cohesin Ring Function and Provide Therapeutic Vulnerabilities in Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 940.

https://doi.org/10.1182/blood-2018-99-117480

Published: 2018

Journal Articles

CXCR4 Has a CXCL12-Independent Essential Role in MLL-AF9 Driven Acute Myeloid Leukemia

Ramprasad Ramakrishnan, Pablo Peña-Martínez, Puneet Agarwal, PhD, Carl Högberg, PhD, Marion Chapellier, PhD, Mansi Shah, PhD, Björn Nilsson, MD PhD, Benjamin L. Ebert, MDPhD, Ravi Bhatia, MD, Marcus Järås, PhD

Blood (2018) 132 (Supplement 1): 774.

https://doi.org/10.1182/blood-2018-99-116137

Published: 2018

Journal Articles

Recurrent Genetic HLA Loss in Acute Myeloid Leukemia Relapsed after Matched Unrelated Allogeneic Hematopoietic Cell Transplant

Blood (2018) 132 (Supplement 1): 817.

https://doi.org/10.1182/blood-2018-99-113911

Published: 2018

Journal Articles

Discovery of a Novel Mechanism of Resistance to Thalidomide Derivatives

Adam S Sperling, MD PhD, Michael Burgess, PhD, Hasmik Keshishian, PhD, Jessica Gasser, PhD, Max Jan, MD PhD, Rohan Sharma, Mariateresa Fulciniti, PhD, Nikhil Munshi, MD, Steven A. Carr, PhD, Benjamin L. Ebert, MDPhD

Blood (2018) 132 (Supplement 1): 949.

https://doi.org/10.1182/blood-2018-99-115110

Published: 2018

Journal Articles

Integrated Genomic and Proteomic Analysis of Murine CLL-like Cells Reveals SF3B1 Mutation to Impact DNA Damage Response and BCR Signaling

Lili Wang, MDPhD, Shanye Yin, PhD, Aina zurita Martinez, Fara Faye Regis, BS, Angela Brooks, PhD, Sarah E. M. Herman, PhD, Elisa Ten Hacken, PhD, Esther Obeng, MD PhD, Dean Campagna, BS, Mark D. Fleming, MD DPhil, Benjamin L. Ebert, MDPhD, Adrian Wiestner, MD, Ignaty Leshchiner, PhD, Gad Getz, PhD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD

Blood (2018) 132 (Supplement 1): 947.

https://doi.org/10.1182/blood-2018-99-117691

Published: 2018

Journal Articles

Calmodulin Inhibition Rescues DBA Models with Ribosomal Protein Deficiency through Reduction of RSK Signaling

Elizabeth R Macari, PhD, Alison M Taylor, PhD, David Raiser, PhD, Kavitha Siva, PhD, Katherine McGrath, Jessica M Humphries, Johan Flygare, MDPhD, Benjamin L. Ebert, MDPhD, Leonard I. Zon, MD

Blood (2016) 128 (22): 332.

https://doi.org/10.1182/blood.V128.22.332.332

Published: 2016

Journal Articles

Reduced Protein Synthesis and p53 Activation in Late-Stage Erythroblasts Mediate the Erythroid Differentiation Defect in Mice with Ribosomal Protein S14 Haploinsufficiency

Rebekka K. Schneider, MD, Marie E. McConkey, PhD, Lisa P. Chu, Benjamin L. Ebert, MDPhD

Blood (2014) 124 (21): 1892.

https://doi.org/10.1182/blood.V124.21.1892.1892

Published: 2014

Journal Articles

Loss of TET2 Function in Myelodysplastic Syndrome Results in Intragenic Hypermethylation and Alterations in mRNA Splicing

Allegra M Lord, Kendell Clement, Rebekka K. Schneider, MD, McConkey Marie, PhD, Michelle C. Chen, Ross L. Levine, MD, Ann Mullally, MD, Naomi Galili, PhD, Abdullah Mahmood Ali, PhD, Azra Raza, MD, Rafael Bejar, MD PhD, Alexander Meissner, PhD, Benjamin L. Ebert, MDPhD

Blood (2014) 124 (21): 775.

https://doi.org/10.1182/blood.V124.21.775.775

Published: 2014

NARROW

Vaccination with a Personalized Dendritic Cell/AML Fusion Cell Vaccine Following Allogeneic Transplantation in a Phase 1 Clinical Trial

Using an in-Vivo Degron-Based Approach to Interrogate Dependencies of Serially Acquired Mutations - Including DNMT3a-R882 and NPM1c - in Acute Myeloid Leukemia

Targeted Sequencing of 7 Genes Can Help Reduce Pathologic Misclassification of MDS

A Novel Inflammatory Index Is Sufficient to Identify Hemophagocytic Lymphohistiocytosis in Adult Patients with Hematologic Malignancies

Congenital X-Linked Myelodysplasia with Tetraploidy Is Associated with De Novo Germline C-Terminal Mutation of SEPT6, a Septin Filament Protein

Loss-of-Function Mutations in Dnmt3a and Tet2 Lead to Accelerated Atherosclerosis and Convergent Macrophage Phenotypes in Mice

Bcor Mutations Cooperate with Tet2 Deficiency to Promote RAS Transformation of Mouse Hematopoietic Progenitors

The Role of Clonal Hematopoiesis of Indeterminate Potential (CHIP) in Multiple Myeloma: Immunomodulator Maintenance Post Autologous Stem Cell Transplant (ASCT) Predicts Better Outcome

CRISPR-Based Functional Genomics Studies Reveal Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins: Implications for Novel Therapeutics across Diverse Neoplasias

Engineered Bcor Mutations Lead to Acute Lymphoblastic Leukemia of Progenitor B-1 Lymphocyte Origin in a Sensitized Background

SNP-Array Genome Wide Association Study Meta-Analysis Identifies Innate Immune Susceptibility Loci Associated with Non-Del(5q) Myelodysplastic Syndromes Predisposition

Multiplex CRISPR/Cas9-Based Genome Editing of Mouse Hematopoietic Stem Cells Recapitulates Acute Erythroid Leukemia and Identifies Therapeutic Targets

STAG2 Mutations Alter Cohesin Ring Function and Provide Therapeutic Vulnerabilities in Acute Myeloid Leukemia

CXCR4 Has a CXCL12-Independent Essential Role in MLL-AF9 Driven Acute Myeloid Leukemia

Recurrent Genetic HLA Loss in Acute Myeloid Leukemia Relapsed after Matched Unrelated Allogeneic Hematopoietic Cell Transplant

Discovery of a Novel Mechanism of Resistance to Thalidomide Derivatives

Integrated Genomic and Proteomic Analysis of Murine CLL-like Cells Reveals SF3B1 Mutation to Impact DNA Damage Response and BCR Signaling

Calmodulin Inhibition Rescues DBA Models with Ribosomal Protein Deficiency through Reduction of RSK Signaling

Reduced Protein Synthesis and p53 Activation in Late-Stage Erythroblasts Mediate the Erythroid Differentiation Defect in Mice with Ribosomal Protein S14 Haploinsufficiency

Loss of TET2 Function in Myelodysplastic Syndrome Results in Intragenic Hypermethylation and Alterations in mRNA Splicing

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American Society of Hematology

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American Society of Hematology

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