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Journal Articles

Targeting Protein Disulfide Isomerase with the Oral Flavonoid Isoquercetin Prevents Venous Thromboembolism in Advanced Cancer: Results of a Multi-Dose, Multi-Center, Phase II Clinical Trial (CATIQ Study)

Jeffrey I. Zwicker, MD, Benjamin L. Schlechter, MD, Jack Davis Stopa, PhD, Howard A. Liebman, MD, Anita Aggarwal, PhDDO, Thomas Caughey, MD, Ken A. Bauer, MD, Nancy Kuemmerle, D.O., Ellice Y. Wong, MD, Ted Wun, MD, Marilyn Mclaughlin, MD, Maneka Puligandla, MS, Donna S Neuberg, ScD, Bruce Furie, MD, Robert C. Flaumenhaft, MD PhD

Blood (2018) 132 (Supplement 1): 985.

https://doi.org/10.1182/blood-2018-99-114946

Published: 2018

Journal Articles

Inhibition of Protein Disulfide Isomerase Ameliorates Vaso-Occlusion and Thrombosis in a Mouse Model of Sickle Cell Disease

Chao Fang, PhD, Anish V. Sharda, MBBS, MPH, Lin Lin, PhD, Robert C. Flaumenhaft, MD PhD, Bruce Furie, MD

Blood (2017) 130 (Supplement 1): 442.

https://doi.org/10.1182/blood.V130.Suppl_1.442.442

Published: 2017

Journal Articles

Extracellular Protein Disulfide Isomerase Regulates Vitronectin during the Initiation of Thrombus Formation

Chao Fang, PhD, Sheryl R. Bowley, PhD, Barbara C. Furie, PhD, Bruce Furie, MD

Blood (2016) 128 (22): 15.

https://doi.org/10.1182/blood.V128.22.15.15

Published: 2016

Journal Articles

PDI Inhibition Blocks Thrombin Generation in Humans By Interfering with Platelet Factor V Activation

Jack D Stopa, PhD, Donna S. Neuberg, ScD, Maneka Puligandla, MS, Bruce Furie, MD, Robert C. Flaumenhaft, MD PhD, Jeffrey I. Zwicker, MD

Blood (2016) 128 (22): 2628.

https://doi.org/10.1182/blood.V128.22.2628.2628

Published: 2016

Journal Articles

ML359, a Small Molecule Inhibitor of Protein Disulfide Isomerase That Prevents Thrombus Formation and Inhibits Oxidoreductase but Not Transnitrosylase Activity

Pavan K Bendapudi, MD, Roelof H Bekendam, MD, Lin Lin, PhD, Mingdong Huang, PhD, Bruce Furie, MD, Robert Flaumenhaft, MD/ PhD

Blood (2014) 124 (21): 2880.

https://doi.org/10.1182/blood.V124.21.2880.2880

Published: 2014

Journal Articles

Animal Models of Arterial and Venous Thrombosis

Bruce Furie, MD, Barbara C. Furie, PhD, Robert Flaumenhaft, MD/ PhD, Jeffrey I. Zwicker, MD

Blood (2014) 124 (21): SCI-2.

https://doi.org/10.1182/blood.V124.21.SCI-2.SCI-2

Published: 2014

Journal Articles

Regulation of Protein Disulfide Isomerase By S-Nitrosylation Controls Its Function during Thrombus Formation

Roelof H Bekendam, MD, Gopal Srila, MD, Pavan K Bendapudi, MD, James R Dilks, Lin Lin, PhD, Sheryl Bowley, PhD, Jack Stopa, PhD, Mingdong Huang, PhD, Bruce Furie, MD, Kevin Croce, MD/ PhD, Robert Flaumenhaft, MD/ PhD

Blood (2014) 124 (21): 93.

https://doi.org/10.1182/blood.V124.21.93.93

Published: 2014

Journal Articles

Rosuvastatin Lowers Circulating Tissue Factor Antigen-Bearing Microparticles In Metastatic Breast Cancer: A Phase II, Multi-Dose, Randomized Trial (MicroSTAT Trial)

Jeffrey I. Zwicker, MD, Erica L. Mayer, MD, Federico Campigotto, MS, Julia Geddings, Herold Christina, M.D., Sheryl Bowley, Ph.D., Gerburg Wulf, MD, Gary Horowitz, MD, Donna S. Neuberg, ScD, Nigel Mackman, PhD, Bruce Furie, MD

Blood (2013) 122 (21): 579.

https://doi.org/10.1182/blood.V122.21.579.579

Published: 2013

Journal Articles

Role of Thiol Isomerase ERp5 in Thrombus Formation

Freda H. Passam, MD, PhD, Lin Lin, PhD, Mingdong Huang, PhD, Jonathan M. Gibbins, BSc, PhD, Bruce Furie, MD, Barbara C. Furie, PhD

Blood (2011) 118 (21): 370.

https://doi.org/10.1182/blood.V118.21.370.370

Published: 2011

Journal Articles

Protein Disulfide Isomerase Inhibitors: A New Class of Antithrombotic Agents

Reema Jasuja, Ph.D., Freda H. Passam, MD, PhD, Daniel R Kennedy, Ph.D., Sarah H Kim, Lotte van Hessem, Lin Lin, PhD, Sucharit S Joshi, MD, James R. Dilks, Bruce Furie, MD, Barbara C. Furie, PhD, Robert C. Flaumenhaft, MD, PhD

Blood (2011) 118 (21): 369.

https://doi.org/10.1182/blood.V118.21.369.369

Published: 2011

Journal Articles

Role of Protein Disulfide Isomerase In Thrombus Formation In a Collagen-Induced Pathway of Thrombus Formation

Lola Bellido Martin, PhD, Bruce Furie, MD, Barbara C. Furie, PhD

Blood (2010) 116 (21): 345.

https://doi.org/10.1182/blood.V116.21.345.345

Published: 2010

Journal Articles

TRAIL/ DR5 Interactions Are Important for Thymic Damage After Allogeneic Bone Marrow Transplantation.

Blood (2009) 114 (22): 234.

https://doi.org/10.1182/blood.V114.22.234.234

Published: 2009

Journal Articles

Intravascular but Not Extravascular Tissue Factor Is Required for Fibrin Generation During Thrombus Formation in Cremaster Arterioles in Living Mice Subjected to Laser Injury.

Vivien Chen, MD, PhD, Glenn Merrill-Skoloff, Li Wang, Samuel Chen, Nigel Mackman, PhD, Mark Taubman, MD, Barbara Furie, PhD, Bruce Furie, MD

Blood (2009) 114 (22): 332.

https://doi.org/10.1182/blood.V114.22.332.332

Published: 2009

Journal Articles

Reduction of Phosphatidylserine Exposure through Copper Chelation Leads to Reduced Fibrin Deposition After Laser Induced Vascular Injury In Vivo.

Reema Jasuja, PhD, Hans-Ulrich Pauer, Regan T Baird, Bruce Furie, MD, Barbara Furie

Blood (2009) 114 (22): 3049.

https://doi.org/10.1182/blood.V114.22.3049.3049

Published: 2009

Journal Articles

Endothelium but Not Platelet-Derived Protein Disulfide Isomerase Is Required for Fibrin Generation during Thrombus Formation in Vivo.

Reema Jasuja, PhD, Jaehyung Cho, PhD, Bruce Furie, MD, Barbara Furie

Blood (2008) 112 (11): 691.

https://doi.org/10.1182/blood.V112.11.691.691

Published: 2008

Journal Articles

Eculizumab Therapy Results in Rapid and Sustained Decreases in Markers of Thrombin Generation and Inflammation in Patients with PNH

Ilene Ceil Weitz, MD, Michael Ghods, BA, Leanne Rochanda, MS, Pedram Prazavi, MD, Jeffrey Zwicker, MD, Bruce Furie, MD, Howard Liebman, MD

Blood (2008) 112 (11): 407.

https://doi.org/10.1182/blood.V112.11.407.407

Published: 2008

Journal Articles

Monitoring Endothelial Cell Activation In Vivo during Thrombus Formation.

Ben T. Atkinson, DPhil, Prathima Nandivada, BSc, Bruce Furie, MD, Barbara C. Furie, PhD

Blood (2007) 110 (11): 294.

https://doi.org/10.1182/blood.V110.11.294.294

Published: 2007

Journal Articles

Endothelial Cell Thiol Isomerases: Potential Role in Thrombus Formation.

Reema Jasuja, PhD, Bruce Furie, MD, Barbara C. Furie, PhD

Blood (2007) 110 (11): 3709.

https://doi.org/10.1182/blood.V110.11.3709.3709

Published: 2007

Journal Articles

Regulation of Tissue Factor Activity: Conformational Changes in Tissue Factor Associated with Cleavage of the Cysteine 186-Cysteine 209 Disulfide Bond.

Jacky Chi Ki Ngo, PhD, Margaret Jacobs, BS, Barbara C. Furie, Ph.D., Bruce Furie, MD

Blood (2007) 110 (11): 270.

https://doi.org/10.1182/blood.V110.11.270.270

Published: 2007

Journal Articles

Crystal Structure of the Bovine Lactadherin C2 Domain, a Potential Anticoagulant, Shows Similarity to Factor V and Factor VIII.

Lin Lin, PhD, Qing Huai, PhD, Mingdong Huang, PhD, Bruce Furie, MD, Barbara C. Furie, PhD

Blood (2006) 108 (11): 194.

https://doi.org/10.1182/blood.V108.11.194.194

Published: 2006

NARROW

Targeting Protein Disulfide Isomerase with the Oral Flavonoid Isoquercetin Prevents Venous Thromboembolism in Advanced Cancer: Results of a Multi-Dose, Multi-Center, Phase II Clinical Trial (CATIQ Study)

Inhibition of Protein Disulfide Isomerase Ameliorates Vaso-Occlusion and Thrombosis in a Mouse Model of Sickle Cell Disease

Extracellular Protein Disulfide Isomerase Regulates Vitronectin during the Initiation of Thrombus Formation

PDI Inhibition Blocks Thrombin Generation in Humans By Interfering with Platelet Factor V Activation

ML359, a Small Molecule Inhibitor of Protein Disulfide Isomerase That Prevents Thrombus Formation and Inhibits Oxidoreductase but Not Transnitrosylase Activity

Animal Models of Arterial and Venous Thrombosis

Regulation of Protein Disulfide Isomerase By S-Nitrosylation Controls Its Function during Thrombus Formation

Rosuvastatin Lowers Circulating Tissue Factor Antigen-Bearing Microparticles In Metastatic Breast Cancer: A Phase II, Multi-Dose, Randomized Trial (MicroSTAT Trial)

Role of Thiol Isomerase ERp5 in Thrombus Formation

Protein Disulfide Isomerase Inhibitors: A New Class of Antithrombotic Agents

Role of Protein Disulfide Isomerase In Thrombus Formation In a Collagen-Induced Pathway of Thrombus Formation

TRAIL/ DR5 Interactions Are Important for Thymic Damage After Allogeneic Bone Marrow Transplantation.

Intravascular but Not Extravascular Tissue Factor Is Required for Fibrin Generation During Thrombus Formation in Cremaster Arterioles in Living Mice Subjected to Laser Injury.

Reduction of Phosphatidylserine Exposure through Copper Chelation Leads to Reduced Fibrin Deposition After Laser Induced Vascular Injury In Vivo.

Endothelium but Not Platelet-Derived Protein Disulfide Isomerase Is Required for Fibrin Generation during Thrombus Formation in Vivo.

Eculizumab Therapy Results in Rapid and Sustained Decreases in Markers of Thrombin Generation and Inflammation in Patients with PNH

Monitoring Endothelial Cell Activation In Vivo during Thrombus Formation.

Endothelial Cell Thiol Isomerases: Potential Role in Thrombus Formation.

Regulation of Tissue Factor Activity: Conformational Changes in Tissue Factor Associated with Cleavage of the Cysteine 186-Cysteine 209 Disulfide Bond.

Crystal Structure of the Bovine Lactadherin C2 Domain, a Potential Anticoagulant, Shows Similarity to Factor V and Factor VIII.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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