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Journal Articles

Clonal evolution leading to ibrutinib resistance in chronic lymphocytic leukemia

Inhye E. Ahn, Chingiz Underbayev, Adam Albitar, Sarah E. M. Herman, Xin Tian, Irina Maric, Diane C. Arthur, Laura Wake, Stefania Pittaluga, Constance M. Yuan, Maryalice Stetler-Stevenson, Susan Soto, Janet Valdez, Pia Nierman, Jennifer Lotter, Liqiang Xi, Mark Raffeld, Mohammed Farooqui, Maher Albitar, Adrian Wiestner
Journal: Blood
Blood (2017) 129 (11): 1469–1479.
https://doi.org/10.1182/blood-2016-06-719294
Published: 2017
Includes: Supplemental data
Journal Articles

Sustained High Rates of Complete Response and Minimal Residual Disease Negativity after 8 Cycles of Carfilzomib (CFZ), Lenalidomide (LEN), and Dexamethasone (DEX) Followed By 2 Years of Lenalidomide Maintenance (CRd-R) in Patients with High-Risk Smoldering Multiple Myeloma: Updated Results of Clinical and Correlative Phase 2 Study

Dickran Kazandjian, MD, Neha S Korde, MD, Mark Roschewski, MD, Sham Mailankody, MD, Candis Morrison, RN, PhD, Elisabet E. Manasanch, MD, Mary L Kwok, MD, Nishant Tageja, MD, Manisha Bhutani, MD, Adriana Zingone, PhD, Rene Costello, Yong Zhang, PhD, Marcia Mulquin, Liz Lamping, Ashley Carpenter, Brenda Roberson, Irina Maric, MD, Katherine R. Calvo, MD PhD, Raul C Braylan, MD, Constance M. Yuan, MD PhD, Maryalice Stetler-Stevenson, MD PhD, Diane C. Arthur, MD, Liza Lindenberg, Karen A. Kurdziel, MD, Peter Choyke, Seth M. Steinberg, PhD, William Figg, Wyndham H. Wilson, MD PhD, Ola Landgren, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3339.
https://doi.org/10.1182/blood.V128.22.3339.3339
Published: 2016
Journal Articles

Sustained Minimal Residual Disease Negativity in Newly Diagnosed Multiple Myeloma (NDMM) Patients Treated with Carfilzomib (CFZ), Lenalidomide (LEN), and Dexamethasone (DEX) Followed By 2 Years of Lenalidomide Maintenance (CRd-R): Updated Results of a Phase 2 Study

Dickran Kazandjian, MD, Neha S Korde, MD, Mark Roschewski, MD, Sham Mailankody, MD, Candis Morrison, RN, PhD, Elisabet E. Manasanch, MD, Mary L Kwok, MD, Nishant Tageja, MD, Manisha Bhutani, MD, Adriana Zingone, PhD, Rene Costello, Yong Zhang, PhD, Marcia Mulquin, Liz Lamping, Ashley Carpenter, Brenda Roberson, Irina Maric, MD, Katherine R. Calvo, MD PhD, Raul C Braylan, MD, Constance M. Yuan, MD PhD, Maryalice Stetler-Stevenson, MD PhD, Diane C. Arthur, MD, Liza Lindenberg, Karen A. Kurdziel, MD, Peter Choyke, Seth M. Steinberg, PhD, William Figg, Wyndham H. Wilson, MD PhD, Ola Landgren, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4527.
https://doi.org/10.1182/blood.V128.22.4527.4527
Published: 2016
Journal Articles

GATA2 deficiency-associated bone marrow disorder differs from idiopathic aplastic anemia

Clinical Trials & Observations
Karthik A. Ganapathi, Danielle M. Townsley, Amy P. Hsu, Diane C. Arthur, Christa S. Zerbe, Jennifer Cuellar-Rodriguez, Dennis D. Hickstein, Sergio D. Rosenzweig, Raul C. Braylan, Neal S. Young, Steven M. Holland, Katherine R. Calvo
Journal: Blood
Blood (2015) 125 (1): 56–70.
https://doi.org/10.1182/blood-2014-06-580340
Published: 2015
Journal Articles

Carfilzomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma: Final Results from the NCI Phase 2 Pilot Study

Ola Landgren, MD PhD, Mark Roschewski, MD, Sham Mailankody, MD, Mary Kwok, MD, Elisabet E. Manasanch, MD, Manisha Bhutani, MD, Nishant Tageja, MD, Dickran Kazandjian, MD, Adriana Zingone, MD PhD, Rene Costello, Debra Burton, Yong Zhang, MD PhD, Peter Wu, George Carter, PA, Marcia Mulquin, RN, Diamond Zuchlinski, RN, Ashley Carpenter, RN, Verena Gounden, MD, Candice Morrison, NP, Irina Maric, MD, Katherine R. Calvo, MD, PhD, Raul C. Braylan, MD, Constance Yuan, MD PhD, Maryalice Stetler-Stevenson, MD PhD, Diane C Arthur, MD, Liza Lindenberg, MD, Kurdziel Karen, MD, Peter Choyke, MD, Seth M. Steinberg, PhD, William D Figg, PharmD, Neha Korde, MD
Journal: Blood
Blood (2014) 124 (21): 4746.
https://doi.org/10.1182/blood.V124.21.4746.4746
Published: 2014
Journal Articles

Minimal Residual Disease (MRD) Testing in Newly Diagnosed Multiple myeloma (MM) Patients: A Prospective Head-to-Head Assessment of Cell-Based, Molecular, and Molecular-Imaging Modalities

Neha Korde, MD, Sham Mailankody, MD, Mark Roschewski, MD, Malek Faham, Chitra Kotwaliwale, Martin Moorhead, PhD, Mary L Kwok, MD, Elisabet E. Manasanch, MD, Manisha Bhutani, MD, Nishant Tageja, MD, Dickran Kazandjian, MD, Rene Costello, Yong Zhang, MD PhD, Adriana Zingone, MD PhD, Debbie Burton, Marcia Mulquin, RN, Ashley Carpenter, RN, Diamond Zuchlinski, RN, Elizabeth Lamping, George Carter, PA, Candis Morrison, Karen Kurdziel, MD, Maria Lindenberg, MD, Roger Kurlander, MD, Irina Maric, MD, Katherine R. Calvo, MD, PhD, Raul C Braylan, MD, Constance Yuan, MD PhD, Maryalice Stetler-Stevenson, MD PhD, Diane C Arthur, MD, Seth M. Steinberg, PhD, William D Figg, PharmD, Peter Choyke, MD, Ola Landgren, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2105.
https://doi.org/10.1182/blood.V124.21.2105.2105
Published: 2014
Journal Articles

GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity

Michael A. Spinner, Lauren A. Sanchez, Amy P. Hsu, Pamela A. Shaw, Christa S. Zerbe, Katherine R. Calvo, Diane C. Arthur, Wenjuan Gu, Christine M. Gould, Carmen C. Brewer, Edward W. Cowen, Alexandra F. Freeman, Kenneth N. Olivier, Gulbu Uzel, Adrian M. Zelazny, Janine R. Daub, Christine D. Spalding, Reginald J. Claypool, Neelam K. Giri, Blanche P. Alter, Emily M. Mace, Jordan S. Orange, Jennifer Cuellar-Rodriguez, Dennis D. Hickstein, Steven M. Holland
Journal: Blood
Blood (2014) 123 (6): 809–821.
https://doi.org/10.1182/blood-2013-07-515528
Published: 2014
Includes: Supplemental data
Journal Articles

Clinical and Correlative Pilot Study Of Carfilzomib, Lenalidomide, and Dexamethasone Followed By Lenalidomide Extended Dosing (CRd – R) In High Risk Smoldering Multiple Myeloma Patients

Ola Landgren, MD, PhD, Sham Mailankody, MD, Mary Kwok, MD, Elisabet E. Manasanch, MD, Manisha Bhutani, MD, Nishant Tageja, MD, Dickran Kazandjian, MD, Adriana Zingone, MD, PhD, Rene Costello, Debra Burton, Yong Zhang, PhD, Peter Wu, George Carter, PA, Marcia Mulquin, RN, Diamond Zuchlinski, RN, Irina Maric, MD, Katherine R Calvo, MD, PhD, Raul C. Braylan, Constance Yuan, MD, PhD, Maryalice Stetler-Stevenson, MD, PhD, Diane C Arthur, M.D., Liza Lindenberg, MD, Karen Kurdziel, MD, Peter Choyke, MD, Seth M. Steinberg, PhD, Mark Roschewski, MD, Neha Korde, MD
Journal: Blood
Blood (2013) 122 (21): 1939.
https://doi.org/10.1182/blood.V122.21.1939.1939
Published: 2013
Journal Articles

Minimal Residual Disease (MRD) Detection By Deep Sequencing In Newly Diagnosed Multiple Myeloma Patients Treated With Carfilzomib, Lenalidomide and Dexamethasone

Sham Mailankody, MD, Neha Korde, MD, Malek Faham, MD, PhD, Mary Kwok, MD, Elisabet E. Manasanch, MD, Manisha Bhutani, MD, Nishant Tageja, MD, Dickran Kazandjian, Li Weng, PhD, Martin Moorhead, PhD, Rene Costello, Yong Zhang, PhD, Adriana Zingone, MD, PhD, Debbie Burton, Peter Wu, Marcia Mulquin, RN, Diamond Zuchlinski, RN, Roger Kurlander, MD, Irina Maric, MD, Katherine R Calvo, MD, PhD, Raul C. Braylan, Constance Yuan, MD, PhD, Maryalice Stetler-Stevenson, MD, PhD, Diane C Arthur, M.D., Mark Roschewski, MD, Ola Landgren, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1902.
https://doi.org/10.1182/blood.V122.21.1902.1902
Published: 2013
Journal Articles

Phase II Clinical and Correlative Study Of Carfilzomib, Lenalidomide, and Dexamethasone Followed By Lenalidomide Extended Dosing (CRD-R) Induces High Rates Of MRD Negativity In Newly Diagnosed Multiple Myeloma (MM) Patients

Neha Korde, MD, Adriana Zingone, MD, PhD, Mary L Kwok, MD, Elisabet E. Manasanch, MD, Manisha Bhutani, MD, Nishant Tageja, MD, Dickran Kazandjian, MD, Sham Mailankody, MD, Rene Costello, Yong Zhang, PhD, Debra Burton, George Carter, PA, Peter Wu, Marcia Mulquin, RN, Diamond Zuchlinski, RN, Irina Maric, MD, Katherine R Calvo, MD, PhD, Raul C. Braylan, Mark Roschewski, MD, Constance Yuan, MD, PhD, Maryalice Stetler-Stevenson, MD, PhD, Diane C Arthur, M.D., Liza Lindenberg, MD, Karen Kurdziel, MD, Pete Choyke, MD, Seth M. Steinberg, PhD, Ola Landgren, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 538.
https://doi.org/10.1182/blood.V122.21.538.538
Published: 2013
Journal Articles

Single Agent Ibrutinib (PCI-32765) Achieves Equally Good and Durable Responses In Chronic Lymphocytic Leukemia (CLL) Patients With and Without Deletion 17p

Mohammed Farooqui, DO, Georg Aue, MD, Janet Valdez, PA, Sabrina Martyr, MD, Jade Jones, Susan Soto, RN, Maryalice Stetler-Stevenson, MD, PhD, Constance Yuan, MD, PhD, Diane C Arthur, M.D., Francine Thomas, B.S., Xin Tian, PhD, Delong Liu, PhD, Irina Maric, MD, Adrian Wiestner, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 673.
https://doi.org/10.1182/blood.V122.21.673.673
Published: 2013
Journal Articles

Clinically Silent Carriers in Families with Myelodysplastic Syndrome Due to GATA2 Mutations

Blanche P Alter, MD, MPH, Neelam Giri, MD, Katherine R Calvo, MD, PhD, Irina Maric, MD, Diane C Arthur, M.D., Dennis D. Hickstein, M.D., Caroline A. Hastings, MD, Michelle A Lee, MD, PhD, Amy Hsu, B.S., Steven M. Holland, MD
Journal: Blood
Blood (2012) 120 (21): 1264.
https://doi.org/10.1182/blood.V120.21.1264.1264
Published: 2012
Journal Articles

Phase II Clinical and Correlative Study of Carfilzomib, Lenalidomide, and Dexamethasone (CRd) in Newly Diagnosed Multiple Myeloma (MM) Patients

Neha Korde, MD, Adriana Zingone, MD, PhD, Mary Kwok, MD, Elisabet E. Manasanch, MD, Rene Costello, Diamond Zuchlinski, RN, Marcia Mulquin, RN, Irina Maric, MD, Katherine R Calvo, MD, PhD, Raul C. Braylan, MD, Constance Yuan, MD, PhD, Prashant Ramesh Tembhare, MD, Maryalice Stetler-Stevenson, MD, PhD, Diane C Arthur, M.D., Mark Raffeld, MD, Liqiang Xi, MD, Peter Choyke, MD, Karen Kurdziel, MD, Liza Lindenberg, MD, Seth M. Steinberg, PhD, Mark Roschewski, MD, Ola Landgren, M.D., Ph.D.
Journal: Blood
Blood (2012) 120 (21): 732.
https://doi.org/10.1182/blood.V120.21.732.732
Published: 2012
Journal Articles

Significance of Bone Marrow Karyotype and Morphology in Patients with Inherited Bone Marrow Failure Syndromes,

Neelam Giri, MD, Blanche P Alter, MD, MPH, Helkha Peredo-Pinto, MD, M. Tarek Elghetany, MD, Irina Maric, MD, Sharon A Savage, MD, Diane C Arthur, M.D.
Journal: Blood
Blood (2011) 118 (21): 3431.
https://doi.org/10.1182/blood.V118.21.3431.3431
Published: 2011
Journal Articles

The lymph node microenvironment promotes B-cell receptor signaling, NF-κB activation, and tumor proliferation in chronic lymphocytic leukemia

Yair Herishanu, Patricia Pérez-Galán, Delong Liu, Angélique Biancotto, Stefania Pittaluga, Berengere Vire, Federica Gibellini, Ndegwa Njuguna, Elinor Lee, Lawrence Stennett, Nalini Raghavachari, Poching Liu, J. Philip McCoy, Mark Raffeld, Maryalice Stetler-Stevenson, Constance Yuan, Richard Sherry, Diane C. Arthur, Irina Maric, Therese White, Gerald E. Marti, Peter Munson, Wyndham H. Wilson, Adrian Wiestner
Journal: Blood
Blood (2011) 117 (2): 563–574.
https://doi.org/10.1182/blood-2010-05-284984
Published: 2011
Includes: Supplemental data
Journal Articles

Allogeneic Hematopoetic Transplantation for CLL: Results of Combination Chemotherapy as Pre-Transplant Targeted Lymphocyte Depletion on Disease Response, Donor Chimerism, and Transplantation Outcomes.

Brian C Shaffer, MD, Marko Modric, David Liewehr, MS, Maryalice Stetler-Stevenson, MD, PhD, Diane C Arthur, MD, Seth Steinberg, PhD, Frances T Hakim, PhD, Kelly Bryant, Jeanne Odom, Paula Layton, BSN, Rachel B Salit, MD, Christoph Rader, PhD, Ronald E Gress, MD, Daniel H Fowler, MD, Michael R Bishop, MD, Steven Z Pavletic, MD
Journal: Blood
Blood (2010) 116 (21): 3476.
https://doi.org/10.1182/blood.V116.21.3476.3476
Published: 2010
Journal Articles

Phase II Trial of Pulse Dosed Lenalidomide In Previously Treated Chronic Lymphocytic Leukemia

Georg Aue, M.D., Susan Soto, RN, Janet Valdez, PA, Diane C Arthur, M.D., Xin Tian, Adrian Wiestner, M.D., Ph.D.
Journal: Blood
Blood (2010) 116 (21): 1383.
https://doi.org/10.1182/blood.V116.21.1383.1383
Published: 2010
Journal Articles

A Phase II Trial of Pulse Dosing Lenalidomide: 3 Weeks On 3 Weeks off in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

Georg Aue, MD, Susan Soto, RN, Janet Valdez, PA, Diane C. Arthur, MD, Mark Roschewski, MD, Adrian Wiestner, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3427.
https://doi.org/10.1182/blood.V114.22.3427.3427
Published: 2009
Journal Articles

Bone Marrow Fibrosis in Patients with Inherited Bone Marrow Failure Syndromes.

Neelam Giri, MD, Irina Maric, MD, Robert Wesley, Diane C. Arthur, MD, Pierre Noel, MD, Sharon A Savage, MD, FAAP, Blanche P. Alter, MD, MPH
Journal: Blood
Blood (2009) 114 (22): 3192.
https://doi.org/10.1182/blood.V114.22.3192.3192
Published: 2009
Journal Articles

Identification of a novel chromosome region, 13q21.33-q22.2, for susceptibility genes in familial chronic lymphocytic leukemia

Clinical Trials & Observations
David Ng, Ousmane Toure, Ming-Hui Wei, Diane C. Arthur, Fatima Abbasi, Laura Fontaine, Gerald E. Marti, Joseph F. Fraumeni, Jr, Lynn R. Goldin, Neil Caporaso, Jorge R. Toro
Journal: Blood
Blood (2006) 109 (3): 916–925.
https://doi.org/10.1182/blood-2006-03-011825
Published: 2006
Includes: Supplemental data