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Journal Articles

Evaluation of the Impact of a Naturally Occurring Beta Hemoglobin Variant, Hb G-Makassar, on Mature Red Blood Cell Function and Pathology in a Sickle Cell Disease Mouse Model

Zachary Kostamo, Jawa Darazim, Britney Hernandez, Alex Pendergast, Jordan Zgodny, Erica N Evans, Yankai Zhang, Ashwin P Patel, Celeste K. Kanne, Elizabeth Budak, Rebecca Jenkins, Daniel Haupt, Valerie Winton, Bo Yan, Adam Hartigan, Haihua Chu, Giuseppe Ciaramella, Vivien A. Sheehan

Blood (2023) 142 (Supplement 1): 2251.

https://doi.org/10.1182/blood-2023-186237

Published: 2023

Journal Articles

Red Cell Rheology and Blood Viscosity in Pediatric Individuals Having Received Allogenic Hematopoietic Stem Cell Transplantation or Ex Vivo Autologous Gene Therapy for Sickle Cell Disease

Ashwin P. Patel, Celeste K. Kanne, Elizabeth O Stenger, Tami D. John, Vivien A. Sheehan

Blood (2023) 142 (Supplement 1): 1076.

https://doi.org/10.1182/blood-2023-188045

Published: 2023

Journal Articles

Radchip: A Laminin-Lined Red Blood Cell (RBC) Adhesion Device for Functional Characterization and Clinical Evaluation of Sickle RBCs at Steady-State

Erica N Evans, Evelyn K Williams, Celeste K. Kanne, Kirby A Fibben, Ashwin P. Patel, Lindsey Abel, Meredith Ellen Fay, Akshay A Patwardhan, Jawa Darazim, Zachary Kostamo, Wilbur Lam, Vivien A. Sheehan

Blood (2023) 142 (Supplement 1): 3657.

https://doi.org/10.1182/blood-2023-186769

Published: 2023

Journal Articles

Functionality of a Peripheral Blood Derived Microglia-like Cell System for Drug Discovery to Treat Sickle Cell Related Chronic Pain

Yankai Zhang, Celeste K. Kanne, Britney N. Hernandez, Michael J. Lacagnina, Peter M. Grace, Mark J. Burish, Vivien A. Sheehan

Blood (2022) 140 (Supplement 1): 2498–2499.

https://doi.org/10.1182/blood-2022-169831

Published: 2022

Journal Articles

GBT021601 Increases Hemoglobin and Improves Red Blood Cell Deformability without Rebound Hyperviscosity upon Drug Clearance in a Sickle Mouse Model

Celeste K. Kanne, Christina Liu, Britney N. Hernandez, Erica N. Evans, Mira P. Pochron, Kobina Dufu, Vivien A. Sheehan

Blood (2022) 140 (Supplement 1): 5393–5394.

https://doi.org/10.1182/blood-2022-169599

Published: 2022

Journal Articles

Development of a High-Throughput Drug Screening System Based on Human Peripheral Blood Derived Microglia-like Cells from Sickle Cell Patients with Chronic Pain

Yankai Zhang, Celeste K. Kanne, Michael J. Lacagnina, Peter M. Grace, Mark J. Burish, Vivien A. Sheehan

Blood (2022) 140 (Supplement 1): 10678–10679.

https://doi.org/10.1182/blood-2022-167510

Published: 2022

Journal Articles

Characterization of Hemoglobin Variants Due to in-Frame Deletions in the β-Globin Gene from CRISPR/Cas9 Gene Correction for Sickle Cell Disease

Alex Alex Pendergast, So Hyun Park, Loren A. Binns, Celeste K. Kanne, Cecile Karsenty, Britney N. Hernandez, Byoungyong Yoo, Yankai Zhang, Gang Bao, Vivien A. Sheehan

Blood (2022) 140 (Supplement 1): 7793–7794.

https://doi.org/10.1182/blood-2022-166931

Published: 2022

Journal Articles

Optimization of an Adherent Microfluidic Device for Use in Sickle Cell Disease

Erica N Evans, Celeste K. Kanne, Evelyn Kendall Williams, Kirby S. Fibben, Meredith A Fay, Wilbur A. Lam, Vivien A. Sheehan

Blood (2022) 140 (Supplement 1): 13011–13012.

https://doi.org/10.1182/blood-2022-167137

Published: 2022

Journal Articles

Identification of Biomarkers That Are Associated with Clinical Complications of Hemoglobin SC Disease and Sickle Cell Anemia

Minke A.E. Rab, Celeste K. Kanne, Mitchel C. Berrevoets, Jennifer Bos, Brigitte A. van Oirschot, Erik Teske, Roger E.G. Schutgens, Gerard Pasterkamp, Richard van Wijk, Eduard J. Van Beers, Vivien A. Sheehan

Blood (2021) 138 (Supplement 1): 962.

https://doi.org/10.1182/blood-2021-145376

Published: 2021

Journal Articles

Use of Red Blood Cell Phenotypes for Second Line Therapy Selection in Sickle Cell Disease

Celeste K. Kanne, Ashwin P Patel, Minke A.E. Rab, Brigitte A. van Oirschot, Jennifer Bos, Evelyn Kendall Williams, Meredith E. Fay, Kirby S. Fibben, Wilbur A. Lam, Richard van Wijk, Vivien A. Sheehan

Blood (2021) 138 (Supplement 1): 2053.

https://doi.org/10.1182/blood-2021-153919

Published: 2021

Journal Articles

Validation of a Peripheral Blood-Derived Microglia-like Cell System

Yankai Zhang, PhD, Celeste K. Kanne, BA, Jennifer N. Tran, DO, Michael J. Lacagnina, PhD, Peter M. Grace, PhD, Mark J. Burish, MD PhD, Vivien A. Sheehan, MDPhD

Blood (2020) 136 (Supplement 1): 12–13.

https://doi.org/10.1182/blood-2020-139888

Published: 2020

Journal Articles

Red Cell Rheology Biomarkers to Assess Cure in Gene-Based Therapies

Celeste K. Kanne, BA, Danielle Guffey, MS, Charles Minard, PhD, Eduard van Beers, MD PhD, Richard van Wijk, PhD, Minke A.E. Rab, MD, Vivien A. Sheehan, MD PhD

Blood (2020) 136 (Supplement 1): 11–12.

https://doi.org/10.1182/blood-2020-138989

Published: 2020

Journal Articles

Rheological Impact of GBT1118 Cessation in a Sickle Mouse Model

Danitza Nebor, PhD, Celeste K. Kanne, BA, Mira Pochron, PhD, Donna Oksenberg, PhD, Vivien A. Sheehan, MD PhD

Blood (2020) 136 (Supplement 1): 9–10.

https://doi.org/10.1182/blood-2020-139912

Published: 2020

Journal Articles

Oxygen Gradient Ektacytometry-Derived Biomarkers Are Associated with the Occurrence of Cerebral Infarction, Acute Chest Syndrome and Vaso-Occlusive Crisis in Sickle Cell Disease

Minke A.E. Rab, MD, Celeste K. Kanne, BA, Brigitte A. van Oirschot, Jennifer Bos, Camille Boisson, Maite E. Houwing, MD, Celine Renoux, PhD, Marije Bartels, MD PhD, Erfan Nur, MDPhD, Marjon H. Cnossen, MD PhD, Philippe Joly, PhD, Romain Fort, MD, Philippe Connes, PhD, Richard van Wijk, PhD, Vivien A. Sheehan, MD PhD, Eduard van Beers, MD PhD

Blood (2020) 136 (Supplement 1): 20–21.

https://doi.org/10.1182/blood-2020-135934

Published: 2020

Journal Articles

Plasma BDNF Levels Are Associated with Stroke in Children with SCD

Julia A. Drexelius, Celeste K. Kanne, BA, Huy D Tran, MD, Hyacinth I Hyacinth, MDPhDMPH, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 3565.

https://doi.org/10.1182/blood-2019-131191

Published: 2019

Journal Articles

Rheological Effects of L-Glutamine in Patients with Sickle Cell Disease

Celeste K. Kanne, BA, Varun Reddy, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 3567.

https://doi.org/10.1182/blood-2019-128891

Published: 2019

Journal Articles

Microglia-like Cells Derived from Hematopoietic Stem and Progenitor Cells Are a Model System to Investigate Chronic Pain in Sickle Cell Disease

Yankai Zhang, PhD, Celeste K. Kanne, BA, Jennifer N. Tran, DO, Michael J. Lacagnina, PhD, Peter M. Grace, PhD, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 3575.

https://doi.org/10.1182/blood-2019-128921

Published: 2019

Journal Articles

Rheological Assessments of Sickle Cell Patients Post Allogeneic Hematopoietic Cell Transplant

Tami D John, MD, Madeleine Lu, BS, Celeste K. Kanne, BA, Minke A.E. Rab, MD, Richard van Wijk, PhD, Sergey S. Shevkoplyas, PhD, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 996.

https://doi.org/10.1182/blood-2019-128946

Published: 2019

Journal Articles

The Oxygenscan Provides Clinically Relevant Biomarkers for Treatment Efficacy That Are Associated with Frequency of Vaso-Occlusive Crisis in Sickle Cell Disease

Minke A.E. Rab, MD, Richard van Wijk, PhD, Celeste K. Kanne, BA, Brigitte A. van Oirschot, Jennifer Bos, Camille Boisson, Maite E. Houwing, MD, Jorn J. Gerritsma, MD, Karin Fijnvandraat, MD PhD, Celine Renoux, PhD, Marije Bartels, MD PhD, Erfan Nur, MD PhD, Marjon H. Cnossen, MD PhD, Philippe Joly, PhD, Romain Fort, MD, Philippe Connes, PhD, Eduard J. van Beers, MD PhD, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 2275.

https://doi.org/10.1182/blood-2019-128870

Published: 2019

Journal Articles

KLF4 Is Needed for Optimal Hydroxyurea Induction of Gamma-Globin in K562 Cells

Alireza Paikari, MD, Ankush Goyal, MA, Celeste K. Kanne, BA, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 971.

https://doi.org/10.1182/blood-2019-131214

Published: 2019

NARROW

Evaluation of the Impact of a Naturally Occurring Beta Hemoglobin Variant, Hb G-Makassar, on Mature Red Blood Cell Function and Pathology in a Sickle Cell Disease Mouse Model

Red Cell Rheology and Blood Viscosity in Pediatric Individuals Having Received Allogenic Hematopoietic Stem Cell Transplantation or Ex Vivo Autologous Gene Therapy for Sickle Cell Disease

Radchip: A Laminin-Lined Red Blood Cell (RBC) Adhesion Device for Functional Characterization and Clinical Evaluation of Sickle RBCs at Steady-State

Functionality of a Peripheral Blood Derived Microglia-like Cell System for Drug Discovery to Treat Sickle Cell Related Chronic Pain

GBT021601 Increases Hemoglobin and Improves Red Blood Cell Deformability without Rebound Hyperviscosity upon Drug Clearance in a Sickle Mouse Model

Development of a High-Throughput Drug Screening System Based on Human Peripheral Blood Derived Microglia-like Cells from Sickle Cell Patients with Chronic Pain

Characterization of Hemoglobin Variants Due to in-Frame Deletions in the β-Globin Gene from CRISPR/Cas9 Gene Correction for Sickle Cell Disease

Optimization of an Adherent Microfluidic Device for Use in Sickle Cell Disease

Identification of Biomarkers That Are Associated with Clinical Complications of Hemoglobin SC Disease and Sickle Cell Anemia

Use of Red Blood Cell Phenotypes for Second Line Therapy Selection in Sickle Cell Disease

Validation of a Peripheral Blood-Derived Microglia-like Cell System

Red Cell Rheology Biomarkers to Assess Cure in Gene-Based Therapies

Rheological Impact of GBT1118 Cessation in a Sickle Mouse Model

Oxygen Gradient Ektacytometry-Derived Biomarkers Are Associated with the Occurrence of Cerebral Infarction, Acute Chest Syndrome and Vaso-Occlusive Crisis in Sickle Cell Disease

Plasma BDNF Levels Are Associated with Stroke in Children with SCD

Rheological Effects of L-Glutamine in Patients with Sickle Cell Disease

Microglia-like Cells Derived from Hematopoietic Stem and Progenitor Cells Are a Model System to Investigate Chronic Pain in Sickle Cell Disease

Rheological Assessments of Sickle Cell Patients Post Allogeneic Hematopoietic Cell Transplant

The Oxygenscan Provides Clinically Relevant Biomarkers for Treatment Efficacy That Are Associated with Frequency of Vaso-Occlusive Crisis in Sickle Cell Disease

KLF4 Is Needed for Optimal Hydroxyurea Induction of Gamma-Globin in K562 Cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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