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Celia Sigua
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Journal Articles

Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3

Prince George, Purva Bali, Srinivas Annavarapu, Anna Scuto, Warren Fiskus, Fei Guo, Celia Sigua, Gautam Sondarva, Lynn Moscinski, Peter Atadja, Kapil Bhalla
Journal: Blood
Blood (2005) 105 (4): 1768–1776.
https://doi.org/10.1182/blood-2004-09-3413
Published: 2005
Journal Articles

Mechanistic role of heat shock protein 70 in Bcr-Abl–mediated resistance to apoptosis in human acute leukemia cells

Fei Guo, Celia Sigua, Purva Bali, Prince George, Warren Fiskus, Anna Scuto, Srinivas Annavarapu, Abdelmoughite Mouttaki, Gautam Sondarva, Sheng Wei, Jie Wu, Julie Djeu, Kapil Bhalla
Journal: Blood
Blood (2005) 105 (3): 1246–1255.
https://doi.org/10.1182/blood-2004-05-2041
Published: 2005
Journal Articles

Molecular Characterization of Human AML Cells with Resistance to Growth-Inhibitory and Apoptotic Effects of Hydroxamic Acid Analogue Histone Deacetylase Inhibitors.

Fei Guo, Ph.D., Celia Sigua, M.S., Purva Bali, M.S., Warren Fiskus, Ph.D., Gautam Sondarva, Ph.D., Srinivas Annavarapu, M.S., Abdelmoughite Mouttaki, B.S., Peter Atadja, Ph.D., Kapil N. Bhalla, M.D.
Journal: Blood
Blood (2004) 104 (11): 1171.
https://doi.org/10.1182/blood.V104.11.1171.1171
Published: 2004
Journal Articles

Synergistic Cytotoxic Effects of a Combination of a Novel Tyrosine Kinase Inhibitor AMN107 and Histone Deacetylase Inhibitor LBH589 Against Bcr-Abl Expressing Human Leukemia Cells.

Anna Scuto, Ph.D., Srinivas Annavarapu, M.S., Purva Bali, M.S., Molly McCullers, Warren Fiskus, Ph.D., Abdelmoughite Mouttaki, B.S., Fei Guo, Ph.D., Celia Sigua, M.S., Gautam Sondarva, Ph.D., Peter Atadja, Ph.D., Paul Manley, Ph.D., Kapil N. Bhalla, M.D.
Journal: Blood
Blood (2004) 104 (11): 1977.
https://doi.org/10.1182/blood.V104.11.1977.1977
Published: 2004
Journal Articles

Molecular Characterization of Human CML Cells with Resistance to the Heat Shock Protein (hsp) 90 Inhibitor 17-Allylamino-Demethoxy Geldanamycin (17-AAG).

Purva Bali, M.S., Warren Fiskus, Ph.D., Fei Guo, Ph.D., Srinivas Annavarapu, M.S., Celia Sigua, M.S., Gautam Sondarva, Ph.D., Abdelmoughite Mouttaki, B.S., Peter Atadja, Ph.D., Paul Manley, Ph.D., Kapil N. Bhalla, M.D.
Journal: Blood
Blood (2004) 104 (11): 1980.
https://doi.org/10.1182/blood.V104.11.1980.1980
Published: 2004