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Chad C. Bjorklund, Ph.D.
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Journal Articles

Absence Of Mutation In Cereblon (CRBN) and DNA Damage Binding Protein 1 (DDB1) Genes In Myeloma Cells and Patients and Its Clinical Significance

Anjan Thakurta, PhD, Anita K Gandhi, PhD, Michelle Waldman, MS, Chad C. Bjorklund, Ph.D., Suzanne Lentzsch, MD, PhD, Stephen A Schey, MD, Yolanda Calle, PhD, Rajani Chelliah, BSc, MSc, Robert Z. Orlowski, M.D., Ph.D, Anup Madan, PhD, Yuhong Ning, Derek Mendy, B.S., Antonia Lopez-Girona, PhD, Peter H Schafer, PhD, Herve Avet-Loiseau, MD, Rajesh Chopra, MD
Journal: Blood
Blood (2013) 122 (21): 3139.
https://doi.org/10.1182/blood.V122.21.3139.3139
Published: 2013
Journal Articles

Blockade of IGF-1R with OSI-906 Overcomes Bortezomib-Resistance in Multiple Myeloma

Deborah J. Kuhn, Ph.D., Hua Wang, Ph.D., Richard Julian Jones, PhD, Chad C. Bjorklund, Ph.D., Robert Z. Orlowski, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 925.
https://doi.org/10.1182/blood.V118.21.925.925
Published: 2011
Journal Articles

Targeting the Wnt/β-Catenin Signaling Pathway and CD44-Mediated Adhesion As a Rational Approach to Overcome Lenalidomide Resistance in Multiple Myeloma

Chad C. Bjorklund, Ph.D., Sharon Lea Aukerman, PhD, Antonia Lopez-Girona, Ph.D., Mohamad Hussein, MD, Rajesh Chopra, PhD, Isere Kuiatse, Ph.D., Deborah J. Kuhn, Ph.D., Caimiao Wei, PhD, Robert Z. Orlowski, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 928.
https://doi.org/10.1182/blood.V118.21.928.928
Published: 2011
Journal Articles

Cereblon Expression Is Required for the Anti-Myeloma Activity of Lenalidomide and Pomalidomide

Yuan Xiao Zhu, PhD, Esteban Braggio, PhD, Chang-Xin Shi, PhD, Jessica Schmidt, Laura Bruins, Steven R. Schuster, MD, Rafael Fonseca, MD, P. Leif Bergsagel, MD, Chad C. Bjorklund, Ph.D., Robert Z. Orlowski, MD, PhD, A. Keith Stewart, MD
Journal: Blood
Blood (2011) 118 (21): 127.
https://doi.org/10.1182/blood.V118.21.127.127
Published: 2011
Journal Articles

Bortezomib Resistance Is Mediated by Increased Signaling through the Insulin-Like Growth Factor-1/Akt Axis.

Deborah J. Kuhn, Ph.D., Chad C. Bjorklund, Ph.D., Valeria Magarotto, M.D., Jairo A. Matthews, B.A., Michael Wang, M.D., Veerabhadran Baladandayuthapani, Ph.D., Robert Z. Orlowski, M.D., Ph.D.
Journal: Blood
Blood (2009) 114 (22): 2739.
https://doi.org/10.1182/blood.V114.22.2739.2739
Published: 2009
Journal Articles

Activation of the Wnt/β-Catenin Pathway Mediates Lenalidomide Resistance in Multiple Myeloma.

Chad C. Bjorklund, Ph.D., Deborah J. Kuhn, Ph.D., B.Sc., Jairo A. Matthews, B.A., Michael Wang, M.D., Veerabhadran Baladandayuthapani, Ph.D., Robert Z. Orlowski, M.D., Ph.D.
Journal: Blood
Blood (2009) 114 (22): 113.
https://doi.org/10.1182/blood.V114.22.113.113
Published: 2009