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Individualizing apheresis processing volumes using a predictive algorithm: Analysis of the CAR T-cell collection protocol utilized in ACIT001/EXC002, a phase lb/ll trial of decentralized production of CAR T-cells for treatment of relapsed/refractory aggressive NHL and ALL

Jennifer Croden, Zackariah Breckenridge, Charles Yin, Carina Debes-Marun, Bindu Thapa, Irwindeep Sandhu, Michael Chu

Blood (2025) 146 (Supplement 1): 5962.

https://doi.org/10.1182/blood-2025-5962

Published: 2025

Journal Articles

Pre-clinical characterization and process development of a BCMA-directed CAR NK-cell therapy product for relapsed/refractory multiple myeloma

Charles Yin, Angela Hamie, Janna Kozuska, Carina Debes-Marun, Bee Tan, Pankaj Tailor, Michael Chu

Blood (2025) 146 (Supplement 1): 7650.

https://doi.org/10.1182/blood-2025-7650

Published: 2025

Journal Articles

Lipid nanoparticle-mediated mRNA transfection enables efficient and safe generation of CAR macrophages.

Felix Chiu, Angela Hamie, Bee Tan, Carina Debes-Marun, Justine Lai, Charles Yin, Pankaj Tailor, Michael Chu

Blood (2025) 146 (Supplement 1): 5918.

https://doi.org/10.1182/blood-2025-5918

Published: 2025

Journal Articles

Alberta Cellular and Immunotherapy (ACIT) 001, Updated Results of Decentralized Production of Second Generation, Anti-CD19/41BB/CD3z Chimeric Antigen Receptor (CAR) T-Cells in Relapsed/Refractory (R/R) Acute Lymphoblastic Leukemia (ALL) and Aggressive Non-Hodgkin Lymphoma (NHL)

Michael P. Chu, Zack Breckenridge, Deanna Hockley, Mona Shafey, Sunil J. Desai, Victor A. Lewis, Peng Wang, Vladimir Sapon-Cousineau, Charles Yin, Carina Debes-Marun, Irwindeep Sandhu

Blood (2024) 144 (Supplement 1): 3464.

https://doi.org/10.1182/blood-2024-209646

Published: 2024

Journal Articles

Gene Expression Profile of Enriched T-Cells Prior to Chimeric Antigen Receptor (CAR) T-Cell Manufacturing Is Predictive of CAR T-Cell Response

Bee S Tan, Charles Yin, Pankajkumar Tailor, Bindu Thapa, Carina Debes-Marun, Deanna Hockley, Irwindeep Sandhu, Michael P. Chu

Blood (2024) 144 (Supplement 1): 4366.

https://doi.org/10.1182/blood-2024-212330

Published: 2024

Journal Articles

CAR T Cell Exhaustion but Not Ex Vivo Cytotoxicity Is Predictive of Patient Clinical Response: An Interim Analysis of ACIT001/EXC002, a Phase Ib/II Trial of Decentralized Production of CAR T Cells for Treatment of Relapsed/Refractory Aggressive NHL and ALL

Charles Yin, Bindu Thapa, Carina Debes-Marun, Zack Breckenridge, Irwindeep Sandhu, Faisal Khan, Michael P. Chu

Blood (2023) 142 (Supplement 1): 2092.

https://doi.org/10.1182/blood-2023-187663

Published: 2023

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Individualizing apheresis processing volumes using a predictive algorithm: Analysis of the CAR T-cell collection protocol utilized in ACIT001/EXC002, a phase lb/ll trial of decentralized production of CAR T-cells for treatment of relapsed/refractory aggressive NHL and ALL

Pre-clinical characterization and process development of a BCMA-directed CAR NK-cell therapy product for relapsed/refractory multiple myeloma

Lipid nanoparticle-mediated mRNA transfection enables efficient and safe generation of CAR macrophages.

Alberta Cellular and Immunotherapy (ACIT) 001, Updated Results of Decentralized Production of Second Generation, Anti-CD19/41BB/CD3z Chimeric Antigen Receptor (CAR) T-Cells in Relapsed/Refractory (R/R) Acute Lymphoblastic Leukemia (ALL) and Aggressive Non-Hodgkin Lymphoma (NHL)

Gene Expression Profile of Enriched T-Cells Prior to Chimeric Antigen Receptor (CAR) T-Cell Manufacturing Is Predictive of CAR T-Cell Response

CAR T Cell Exhaustion but Not Ex Vivo Cytotoxicity Is Predictive of Patient Clinical Response: An Interim Analysis of ACIT001/EXC002, a Phase Ib/II Trial of Decentralized Production of CAR T Cells for Treatment of Relapsed/Refractory Aggressive NHL and ALL

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ASH Publications

American Society of Hematology

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Individualizing apheresis processing volumes using a predictive algorithm: Analysis of the CAR T-cell collection protocol utilized in ACIT001/EXC002, a phase lb/ll trial of decentralized production of CAR T-cells for treatment of relapsed/refractory aggressive NHL and ALL

Pre-clinical characterization and process development of a BCMA-directed CAR NK-cell therapy product for relapsed/refractory multiple myeloma

Lipid nanoparticle-mediated mRNA transfection enables efficient and safe generation of CAR macrophages.

Alberta Cellular and Immunotherapy (ACIT) 001, Updated Results of Decentralized Production of Second Generation, Anti-CD19/41BB/CD3z Chimeric Antigen Receptor (CAR) T-Cells in Relapsed/Refractory (R/R) Acute Lymphoblastic Leukemia (ALL) and Aggressive Non-Hodgkin Lymphoma (NHL)

Gene Expression Profile of Enriched T-Cells Prior to Chimeric Antigen Receptor (CAR) T-Cell Manufacturing Is Predictive of CAR T-Cell Response

CAR T Cell Exhaustion but Not Ex Vivo Cytotoxicity Is Predictive of Patient Clinical Response: An Interim Analysis of ACIT001/EXC002, a Phase Ib/II Trial of Decentralized Production of CAR T Cells for Treatment of Relapsed/Refractory Aggressive NHL and ALL

Email alerts

ASH Publications

American Society of Hematology

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