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Chie Onishi
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Journal Articles

Cxcr4 low FLT3/ITD + Cells Exhibit Enhanced Resistance to the FLT3 Inhibitor Quizartinib Compared to Cxcr4 high FLT3/ITD + Cells By Elevating Runx1 Expression

Seiji Fukuda, MD PhD, Chie Onishi, MD PhD, Takeshi Taketani, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2558.
https://doi.org/10.1182/blood-2019-129513
Published: 2019
Journal Articles

Proteasome Inhibitors and a Fusicoccin Derivative (ISIR-042) Cooperatively Inhibit Proliferation of Myeloma Cells through Induction of C/EBP-Homologous Protein (CHOP/GADD153)

Takaaki Miyake, Yoshio Honma, Tsutomu Takahashi, Koshi Kawakami, Takahiro Okada, Satoshi Kumanomido, Fumiyoshi Ikejiri, Yumi Jo, Chie Onishi, Ichiro Moriyama, Inoue Masaya, Ritsuro Suzuki, MD PhD, Junji Suzumiya, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5657.
https://doi.org/10.1182/blood.V128.22.5657.5657
Published: 2016
Journal Articles

Flt3/ITD Confers Resistance to FLT3 Inhibitor AC220 By up-Regulating Runx1

Tomohiro Hirade, MD, Mariko Abe, MD, Chie Onishi, MD, Seiji Yamaguchi, MD PhD, Seiji Fukuda, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2223.
https://doi.org/10.1182/blood.V124.21.2223.2223
Published: 2014
Journal Articles

Flt3/ITD Enhances Hematopoietic Cell Migration Towards Chemokine CCL2 Independent of Blocking the Negative Feedback Mechanism on Rho-Associated Kinase

Seiji Fukuda, MD PhD, Chie Onishi, MD, Tomohiro Hirade, MD, Mariko Abe, MD, Takeshi Taketani, MD PhD, Seiji Yamaguchi, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3597.
https://doi.org/10.1182/blood.V124.21.3597.3597
Published: 2014
Journal Articles

Flt3/ITD Blocks Myeloid Differentiation Of Hematopoietic Cells By Up-Regulating Runx1

Tomohiro Hirade, MD, Mariko Abe, MD, Chie Onishi, MD, Seiji Yamaguchi, MD, Seiji Fukuda, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3808.
https://doi.org/10.1182/blood.V122.21.3808.3808
Published: 2013
Journal Articles

The Internal-Tandem-Duplication of Flt3 Mutations Augment Chemotaxis in Hematopoietic Cells by Blocking the Down-Regulation of Rho-Associated Kinase That Is Induced by SDF1/CXCR4 Signaling

Chie Onishi, MD, Satomi Mori, MD, Tomohiro Hirade, MD, Mariko Abe, MD, Seiji Yamaguchi, MD, Reuben Kapur, PhD, Seiji Fukuda, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1319.
https://doi.org/10.1182/blood.V120.21.1319.1319
Published: 2012
Journal Articles

The Internal-Tandem-Duplication of Flt3 Mutation Generates Growth Inhibitory Signals in Mouse Hematopoietic Progenitor Cells by Down-Regulating Pbx1 Expression Via P21 cdkn1a .

Seiji Fukuda, MD, PhD, Mariko Abe, MD, Tomohiro Hirade, MD, Chie Onishi, MD, Louis M. Pelus, PhD, Seiji Yamaguchi, MD
Journal: Blood
Blood (2012) 120 (21): 2340.
https://doi.org/10.1182/blood.V120.21.2340.2340
Published: 2012
Journal Articles

The Concurrent Mutations in Hematological Malignancies with NUP98 -Fusion Genes Are Associated with Clinical Prognosis

Takeshi Taketani, MD, PhD, Tomohiko Taki, MD, PhD, Seiji Fukuda, MD, PhD, Mizuki Hyuga, Chie Onishi, MD, Seiji Yamaguchi, MD, Yasuhide Hayashi, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1480.
https://doi.org/10.1182/blood.V118.21.1480.1480
Published: 2011
Journal Articles

High Frequencies of Simultaneous FLT3-ITD, WT1, and KIT mutations in NUP98 -Related Hematologic Malignancies.

Takeshi Taketani, Tomohiko Taki, Seiji Fukuda, MD, PhD, Chie Onishi, MD, Mariko Abe, MD, Seiji Yamaguchi, MD, Yasuhide Hayashi
Journal: Blood
Blood (2009) 114 (22): 2620.
https://doi.org/10.1182/blood.V114.22.2620.2620
Published: 2009