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Journal Articles

A Six-Protein Activity Signature Defines Favorable Response to Selinexor Treatment for Patients with Diffuse Large B-Cell Lymphoma (DLBCL)

Christopher J. Walker, PhD, Yao Shen, PhD, Mariano Alvarez, PhD, Hua Chang, PhD, Jatin Shah, MD, Sharon Shacham, PhD MBA, Andrea Califano, Dr, Yosef Landesman, PhD

Blood (2020) 136 (Supplement 1): 31–32.

https://doi.org/10.1182/blood-2020-142004

Published: 2020

Journal Articles

Differential Impact of Prognostically Significant Gene Mutations in Acute Myeloid Leukemia (AML) Patients (Pts) Older Than 70 Years (y) Treated with Cytarabine-Based Induction Therapy

Marius Bill, MD PhD, Jessica Kohlschmidt, PhD, Krzysztof Mrózek, MDPhD, Deedra Nicolet, MS, Christopher J. Walker, PhD, Dimitrios Papaioannou, MD, James S. Blachly, MD, Shelley Orwick, BS, Eunice S. Wang, MD, Jonathan E. Kolitz, MD, Bayard L. Powell, MD, Andrew J Carroll, PhD, Ramiro Garzon, MD, Richard M. Stone, MD, John C. Byrd, MD, Clara D. Bloomfield, MD, Ann-Kathrin Eisfeld, MD

Blood (2020) 136 (Supplement 1): 40–41.

https://doi.org/10.1182/blood-2020-141663

Published: 2020

Journal Articles

Poor Treatment Outcomes of Young (<60 Years) African American Patients (Pts) Diagnosed with Acute Myeloid Leukemia (AML) (Alliance)

Blood (2020) 136 (Supplement 1): 5–7.

https://doi.org/10.1182/blood-2020-140999

Published: 2020

Journal Articles

Meta-Analysis of Genome-Wide Association Studies of Acute Myeloid Leukemia (AML) Patients Identifies Variants Associated with Risk of 11q23/ KMT2A -Translocated and Core-Binding Factor (CBF) AML and Suggests a Role for Transcription Elongation in Leukemogenesis

Blood (2020) 136 (Supplement 1): 29–30.

https://doi.org/10.1182/blood-2020-141653

Published: 2020

Journal Articles

Next-Generation RNA Sequencing-Based Analysis Identifies a Novel Set of Prognostic Micrornas (miRs) in Cytogenetically Normal Acute Myeloid Leukemia (CN-AML)

Dimitrios Papaioannou, MD, Deedra Nicolet, MS, Kellie J Archer, PhD, Allison Walker, Krzysztof Mrózek, MD PhD, Andrew J. Carroll, PhD, Jessica Kohlschmidt, PhD, Ann-Kathrin Eisfeld, MD, Marius Bill, MD PhD, Christopher J. Walker, PhD, Geoffrey L. Uy, MD, Bayard L Powell, MD, Jonathan E. Kolitz, MD, Richard Stone, MD, John C. Byrd, MD, Ramiro Garzon, MD, Clara D. Bloomfield, MD

Blood (2019) 134 (Supplement_1): 2694.

https://doi.org/10.1182/blood-2019-125727

Published: 2019

Journal Articles

Personalized Oncology in Acute Myeloid Leukemia (AML): Validation of the Prognostic Value of the Knowledge Bank Algorithm in Patients (Pts) Treated on Cancer and Leukemia Group B (CALGB)/Alliance Protocols

Marius Bill, MD PhD, Krzysztof Mrózek, MD PhD, Jessica Kohlschmidt, PhD, Deedra Nicolet, MS, Brian Giacopelli, BS, Christopher J. Walker, PhD, Dimitrios Papaioannou, MD, Ann-Kathrin Eisfeld, MD, Jonathan E. Kolitz, MD, Bayard L Powell, MD, Andrew J. Carroll, PhD, Richard M. Stone, MD, John C. Byrd, MD, Ramiro Garzon, MD, Christopher C. Oakes, PhD, Clara D. Bloomfield, MD

Blood (2019) 134 (Supplement_1): 182.

https://doi.org/10.1182/blood-2019-128623

Published: 2019

Journal Articles

The 2017 European Leukemianet Genetic Risk Classification Performs Poorly in Older Patients with Acute Myeloid Leukemia (AML) and Should be Refined to Identify Patients Requiring Additional or Alternative Treatment

Ann-Kathrin Eisfeld, MD, Jessica Kohlschmidt, PhD, Krzysztof Mrózek, MD PhD, Deedra Nicolet, MS, Alice S. Mims, MD, Dimitrios Papaioannou, MD, Christopher J. Walker, PhD, James S. Blachly, MD, Sophia E. Maharry, Andrew J. Carroll, PhD, Richard M. Stone, MD, Bayard L Powell, MD, Albert de la Chapelle, MD PhD, Eunice S. Wang, MD, Jonathan E. Kolitz, MD, John C. Byrd, MD, Clara D. Bloomfield, MD

Blood (2019) 134 (Supplement_1): 2681.

https://doi.org/10.1182/blood-2019-130076

Published: 2019

Journal Articles

Distinct Gene Expression Profiles and Mutations Associate with Outcome in Younger Adults with De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) (Alliance)

Christopher J. Walker, PhD, Ann-Kathrin Eisfeld, MD, Hatice G Ozer, PhD, Jessica Kohlschmidt, PhD, Deedra Nicolet, Krzysztof Mrózek, MD PhD, Dimitrios Papaioannou, MD, Luke K Genutis, BS, Bayard L Powell, MD, Geoffrey L. Uy, MD, Jonathan E. Kolitz, MD, Andrew J. Carroll, PhD, Richard Stone, MD, Ramiro Garzon, MD, John C. Byrd, MD, Albert de la Chapelle, MD PhD, Clara D. Bloomfield, MD

Blood (2019) 134 (Supplement_1): 1247.

https://doi.org/10.1182/blood-2019-127478

Published: 2019

Journal Articles

Additional Gene Mutations Refine the 2017 European Leukemianet (ELN) Classification of Adult Patients (Pts) with De Novo Acute Myeloid Leukemia (AML) Aged <60 Years: An Analysis of Alliance for Clinical Trials in Oncology (Alliance) Studies

Ann-Kathrin Eisfeld, MD, Jessica Kohlschmidt, PhD, Krzysztof Mrózek, MD PhD, Alice S. Mims, MD, Christopher J. Walker, PhD, Deedra Nicolet, MS, James S. Blachly, MD, Andrew J. Carroll, PhD, Jonathan E. Kolitz, MD, Bayard L. Powell, MD, Richard M. Stone, MD, Albert de la Chapelle, MD PhD, John C. Byrd, MD, Clara D. Bloomfield, MD

Blood (2018) 132 (Supplement 1): 2740.

https://doi.org/10.1182/blood-2018-99-119994

Published: 2018

Journal Articles

Uniparental Disomies (UPD) of Chromosome 13q Is Associated with Shorter Disease-Free Survival in Adult Patients (Pts) with De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML)

Christopher J. Walker, PhD, Jessica Kohlschmidt, PhD, Ann-Kathrin Eisfeld, MD, Krzysztof Mrózek, MD PhD, Deedra Nicolet, MS, James S. Blachly, MD, Christopher C. Oakes, Shelley Orwick, BS, Dimitrios Papaioannou, MD, Bayard L. Powell, MD, Jonathan E. Kolitz, MD, Andrew J. Carroll, PhD, Richard M. Stone, MD, John C. Byrd, MD, Albert de la Chapelle, MD PhD, Clara D. Bloomfield, MD

Blood (2018) 132 (Supplement 1): 2777.

https://doi.org/10.1182/blood-2018-99-115389

Published: 2018

Journal Articles

Genome-Wide Association Study (GWAS) Identifies a Significant Acute Myeloid Leukemia (AML) Susceptibility Locus Near BICRA

Blood (2018) 132 (Supplement 1): 85.

https://doi.org/10.1182/blood-2018-99-115170

Published: 2018

Journal Articles

A 17-Gene Leukemia Stem Cell (LSC) Score in Adult Patients (Pts) with Acute Myeloid Leukemia (AML) Reveals a Distinct Mutational Landscape and Refines Current European Leukemianet (ELN) Genetic Risk Stratification

Marius Bill, MD PhD, Deedra Nicolet, MS, Ann-Kathrin Eisfeld, MD, Krzysztof Mrózek, MDPhD, Christopher J. Walker, PhD, Jessica Kohlschmidt, PhD, Dimitrios Papaioannou, MD, Jonathan E. Kolitz, MD, Bayard L. Powell, MD, John C. Byrd, MD, Ramiro Garzon, MD, Clara D. Bloomfield, MD

Blood (2018) 132 (Supplement 1): 289.

https://doi.org/10.1182/blood-2018-99-115114

Published: 2018

Journal Articles

Mutations in Genes Associated with Familial Predisposition to Myeloid Neoplasms: Their Frequency and Associations with Pretreatment Characteristics in Adult Patients (Pts) with Presumably Sporadic De Novo Acute Myeloid Leukemia (AML)

Ann-Kathrin Eisfeld, MD, Jessica Kohlschmidt, PhD, Krzysztof Mrózek, MD PhD, Alice S. Mims, MD, Christopher J. Walker, PhD, Deedra Nicolet, MS, James S. Blachly, MD, Luke K Genutis, BS, Andrew J. Carroll, PhD, Bayard L. Powell, MD, Jonathan E. Kolitz, MD, Richard M. Stone, MD, Albert de la Chapelle, MD PhD, John C. Byrd, MD, Clara D. Bloomfield, MD

Blood (2018) 132 (Supplement 1): 1478.

https://doi.org/10.1182/blood-2018-99-120085

Published: 2018

Journal Articles

Mutational Landscape and Clinical Outcome Associated with Different Rearrangements Involving 11q23/ MLL in De Novo Acute Myeloid Leukemia (AML)

Marius Bill, MD PhD, Ann-Kathrin Eisfeld, MD, Krzysztof Mrózek, MDPhD, Jessica Kohlschmidt, PhD, Deedra Nicolet, MS, Christopher J. Walker, PhD, James S. Blachly, MD, Andrew Carroll, PhD, Jonathan E. Kolitz, MD, Eunice S. Wang, MD, Bayard L. Powell, MD, Richard M. Stone, MD, Albert de la Chapelle, MD PhD, John C. Byrd, MD, Clara D. Bloomfield, MD

Blood (2017) 130 (Supplement 1): 3960.

https://doi.org/10.1182/blood.V130.Suppl_1.3960.3960

Published: 2017

Journal Articles

Neurofibromin 1 gene Mutations Are Recurrent Events in Adult Patients with Acute Myeloid Leukemia (AML), Associate with Poor Outcome and Refine the Adverse European Leukemianet (ELN) Risk Category

Ann-Kathrin Eisfeld, MD, Jessica Kohlschmidt, PhD, Krzysztof Mrózek, MDPhD, Alice S. Mims, MD MSCR, Christopher J. Walker, PhD, James S. Blachly, MD, Deedra Nicolet, MS, Shelley Orwick, BS, Sofia E. Maharry, Andrew Carroll, PhD, Bayard L. Powell, MD, Jonathan E. Kolitz, MD, Eunice S. Wang, MD, Richard M. Stone, MD, Albert de la Chapelle, MD PhD, John C. Byrd, MD, Clara D. Bloomfield, MD

Blood (2017) 130 (Supplement 1): 186.

https://doi.org/10.1182/blood.V130.Suppl_1.186.186

Published: 2017

Journal Articles

Molecular Landscape and Clinical Features of Acute Myeloid Leukemia (AML) with Complex Karyotype (CK)

Krzysztof Mrózek, MDPhD, Ann-Kathrin Eisfeld, MD, Jessica Kohlschmidt, PhD, Andrew J. Carroll, III, PhD, Deedra Nicolet, MS, James S. Blachly, MD, Christopher J. Walker, PhD, Eunice S. Wang, MD, Geoffrey L. Uy, MD, Jonathan E. Kolitz, MD, Bayard L. Powell, MD, William Blum, MD, Richard M. Stone, MD, John C. Byrd, MD, Clara D. Bloomfield, MD

Blood (2017) 130 (Supplement 1): 1404.

https://doi.org/10.1182/blood.V130.Suppl_1.1404.1404

Published: 2017

Journal Articles

Mutation Patterns Identify Adult Patients with De Novo Acute Myeloid Leukemia (AML) Aged 60 Years or Older Who Respond Favorably to Standard Chemotherapy: an Analysis of Alliance Studies

Ann-Kathrin Eisfeld, MD, Jessica Kohlschmidt, PhD, Krzysztof Mrózek, MDPhD, James S. Blachly, MD, Christopher J. Walker, PhD, Deedra Nicolet, MS, Shelley Orwick, BS, Andrew Carroll, PhD, Richard M. Stone, MD, Eunice S. Wang, MD, Jonathan E. Kolitz, MD, Bayard L. Powell, MD, Albert de la Chapelle, MD PhD, John C. Byrd, MD, Clara D. Bloomfield, MD

Blood (2017) 130 (Supplement 1): 103.

https://doi.org/10.1182/blood.V130.Suppl_1.103.103

Published: 2017

Journal Articles

Micro RNA-3662 Located within the Major Hematopoietic Differentiation Quantitative Trait Locus on Chromosome 6q23 Acts As a Tumor Suppressor By Direct Targeting of the NF-ĸB Transcriptional Activation Pathway

Sophia E. Maharry, Sujay Mehta, Sandya Liyanarachchi, MS, Christopher J. Walker, PhD, Clara D. Bloomfield, MD, Albert de la Chapelle, MD PhD, Ann-Kathrin Eisfeld, MD

Blood (2014) 124 (21): 2216.

https://doi.org/10.1182/blood.V124.21.2216.2216

Published: 2014

NARROW

A Six-Protein Activity Signature Defines Favorable Response to Selinexor Treatment for Patients with Diffuse Large B-Cell Lymphoma (DLBCL)

Differential Impact of Prognostically Significant Gene Mutations in Acute Myeloid Leukemia (AML) Patients (Pts) Older Than 70 Years (y) Treated with Cytarabine-Based Induction Therapy

Poor Treatment Outcomes of Young (<60 Years) African American Patients (Pts) Diagnosed with Acute Myeloid Leukemia (AML) (Alliance)

Meta-Analysis of Genome-Wide Association Studies of Acute Myeloid Leukemia (AML) Patients Identifies Variants Associated with Risk of 11q23/ KMT2A -Translocated and Core-Binding Factor (CBF) AML and Suggests a Role for Transcription Elongation in Leukemogenesis

Next-Generation RNA Sequencing-Based Analysis Identifies a Novel Set of Prognostic Micrornas (miRs) in Cytogenetically Normal Acute Myeloid Leukemia (CN-AML)

Personalized Oncology in Acute Myeloid Leukemia (AML): Validation of the Prognostic Value of the Knowledge Bank Algorithm in Patients (Pts) Treated on Cancer and Leukemia Group B (CALGB)/Alliance Protocols

The 2017 European Leukemianet Genetic Risk Classification Performs Poorly in Older Patients with Acute Myeloid Leukemia (AML) and Should be Refined to Identify Patients Requiring Additional or Alternative Treatment

Distinct Gene Expression Profiles and Mutations Associate with Outcome in Younger Adults with De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) (Alliance)

Additional Gene Mutations Refine the 2017 European Leukemianet (ELN) Classification of Adult Patients (Pts) with De Novo Acute Myeloid Leukemia (AML) Aged <60 Years: An Analysis of Alliance for Clinical Trials in Oncology (Alliance) Studies

Uniparental Disomies (UPD) of Chromosome 13q Is Associated with Shorter Disease-Free Survival in Adult Patients (Pts) with De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML)

Genome-Wide Association Study (GWAS) Identifies a Significant Acute Myeloid Leukemia (AML) Susceptibility Locus Near BICRA

A 17-Gene Leukemia Stem Cell (LSC) Score in Adult Patients (Pts) with Acute Myeloid Leukemia (AML) Reveals a Distinct Mutational Landscape and Refines Current European Leukemianet (ELN) Genetic Risk Stratification

Mutations in Genes Associated with Familial Predisposition to Myeloid Neoplasms: Their Frequency and Associations with Pretreatment Characteristics in Adult Patients (Pts) with Presumably Sporadic De Novo Acute Myeloid Leukemia (AML)

Mutational Landscape and Clinical Outcome Associated with Different Rearrangements Involving 11q23/ MLL in De Novo Acute Myeloid Leukemia (AML)

Neurofibromin 1 gene Mutations Are Recurrent Events in Adult Patients with Acute Myeloid Leukemia (AML), Associate with Poor Outcome and Refine the Adverse European Leukemianet (ELN) Risk Category

Molecular Landscape and Clinical Features of Acute Myeloid Leukemia (AML) with Complex Karyotype (CK)

Mutation Patterns Identify Adult Patients with De Novo Acute Myeloid Leukemia (AML) Aged 60 Years or Older Who Respond Favorably to Standard Chemotherapy: an Analysis of Alliance Studies

Micro RNA-3662 Located within the Major Hematopoietic Differentiation Quantitative Trait Locus on Chromosome 6q23 Acts As a Tumor Suppressor By Direct Targeting of the NF-ĸB Transcriptional Activation Pathway

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American Society of Hematology

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