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Journal Articles

Puma Is The Critical BH3-Only Protein Mediating Apoptosis In The Nup98-HoxD13 (NHD13) Mouse Model Of Human MDS

Andrew Guirguis, MBBS, FRACP, FRCPA, David J. Curtis, M.D., Ph.D., Christopher Slape, PhD, Jesslyn Saw, Andrew H Wei, MBBS, PhD, Laura M Failla, Philippe Bouillet, PhD, Andreas Strasser, PhD

Blood (2013) 122 (21): 1563.

https://doi.org/10.1182/blood.V122.21.1563.1563

Published: 2013

Journal Articles

Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model

Sarah Greenblatt, Li Li, Christopher Slape, Bao Nguyen, Rachel Novak, Amy Duffield, David Huso, Stephen Desiderio, Michael J. Borowitz, Peter Aplan, Donald Small

Blood (2012) 119 (12): 2883–2894.

https://doi.org/10.1182/blood-2011-10-382283

Published: 2012

Includes: Supplemental data

Journal Articles

Knock-in of a FLT3 Internal Tandem Duplication Mutation Cooperates with a NUP98-HOXD13 Fusion to Generate Acute Myeloid Leukemia

Sarah M Greenblatt, Li Li, PhD, Christopher Slape, PhD, Rachel L Novak, PhD, Amy S. Duffield, MD, PhD, Bao Nguyen, M.S., David Huso, D.V.M., Ph.D., Michael J. Borowitz, MD, PhD, Peter Aplan, MD, Donald Small, MD, PhD

Blood (2011) 118 (21): 865.

https://doi.org/10.1182/blood.V118.21.865.865

Published: 2011

Journal Articles

Enforced Expression of Lin28b Drives Development of Peripheral T Cell Lymphoma In Vivo

Sarah H Beachy, PhD, Masahiro Onozawa, M.D. Ph.D., Yang Jo Chung, PhD, Christopher Slape, PhD, Sven Bilke, PhD, Princy Francis, PhD, Marbin Pineda, MS, Robert L Walker, BS, Paul S. Meltzer, MD, PhD, Peter Aplan, MD

Blood (2011) 118 (21): 1392.

https://doi.org/10.1182/blood.V118.21.1392.1392

Published: 2011

Journal Articles

Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice

David Caudell, David P. Harper, Rachel L. Novak, Rachel M. Pierce, Christopher Slape, Linda Wolff, Peter D. Aplan

Blood (2010) 115 (6): 1194–1203.

https://doi.org/10.1182/blood-2009-04-216184

Published: 2010

Includes: Supplemental data

Journal Articles

Knock-in of a FLT3 Internal Tandem Duplication Mutation Cooperates with a NUP98-HOXD13 Fusion to Generate Acute Leukemia in a Mouse Model.

Sarah M Greenblatt, BS, Biology, Li Li, MD, PhD, Christopher Slape, PhD, David Huso, Peter D. Aplan, MD, Donald Small, MD, PhD

Blood (2009) 114 (22): 2961.

https://doi.org/10.1182/blood.V114.22.2961.2961

Published: 2009

Journal Articles

Identification of Genes That Collaborate with CALM-AF10 to Induce Leukemia by Retroviral Insertional Mutagenesis and Candidate Gene Sequencing

David Caudell, DVM, PhD, Rachel M. Pierce, David P. Harper, MD, Rachel L. Novak, PhD, Christopher Slape, PhD, Linda Wolff, PhD, Peter D. Aplan, MD

Blood (2008) 112 (11): 3787.

https://doi.org/10.1182/blood.V112.11.3787.3787

Published: 2008

Journal Articles

Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras , Kras , and Cbl

Christopher Slape, Leah Y. Liu, Sarah Beachy, Peter D. Aplan

Blood (2008) 112 (5): 2017–2019.

https://doi.org/10.1182/blood-2008-01-135186

Published: 2008

Includes: Supplemental data

Journal Articles

A NUP98-HOXD13 Fusion Gene Induces a Transplantable Myelodysplastic Syndrome in Mice.

Yang Jo Chung, PhD, Chul Won Choi, MD, Ph.D, Christopher Slape, Ph.D, Terry Fry, MD, Peter D. Aplan, MD

Blood (2007) 110 (11): 401.

https://doi.org/10.1182/blood.V110.11.401.401

Published: 2007

Journal Articles

A NUP98-HOXD13 Fusion Gene Impairs Differentiation of T and B Lymphocytes.

Chul Won Choi, MD, PhD, Yang Jo Chung, PhD, Christopher Slape, PhD, Peter D. Aplan, MD

Blood (2007) 110 (11): 2650.

https://doi.org/10.1182/blood.V110.11.2650.2650

Published: 2007

Journal Articles

Leukemic Transformation in Mice Expressing a NUP98-HOXD13 Transgene Is Accompanied by Spontaneous Mutations in Receptor Tyrosine Kinase Pathway Genes.

Christopher Slape, PhD, Leah Y. Liu, Peter D. Aplan, MD

Blood (2007) 110 (11): 1614.

https://doi.org/10.1182/blood.V110.11.1614.1614

Published: 2007

Journal Articles

Retroviral Insertion Tagging Identifies Mn1 as a Specific Collaborator of NUP98 - HOXD13 in a Murine Model of Leukemogenesis.

Christopher Slape, PhD, Helge Hartung, MD, Yingwei Lin, PhD, MD, Juraj Bies, PhD, Linda Wolff, PhD, Peter D. Aplan, MD

Blood (2006) 108 (11): 1409.

https://doi.org/10.1182/blood.V108.11.1409.1409

Published: 2006

Journal Articles

Acceleration of Leukemogenesis in NUP98-HOXD13 Transgenic Mice by Infection with the MOL4070LTR Virus, and Identification of Collaborating Genes.

Christopher Slape, PhD, Yingwei Lin, MD, PhD, Juraj Bies, PhD, Linda Wolff, PhD, Peter D. Aplan, MD

Blood (2005) 106 (11): 1597.

https://doi.org/10.1182/blood.V106.11.1597.1597

Published: 2005

Journal Articles

NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia

Ying-Wei Lin, Christopher Slape, Zhenhua Zhang, Peter D. Aplan

Blood (2005) 106 (1): 287–295.

https://doi.org/10.1182/blood-2004-12-4794

Published: 2005

Includes: Supplemental data

Journal Articles

NUP98-HOXD13 Transgenic Mice Develop Myelodysplastic Syndrome, Acute Myeloid Leukemia, and Pre-T Lymphoblastic Leukemia.

Yingwei Lin, MD, PhD, Christopher Slape, PhD, Zhenhua Zhang, Peter D. Aplan, MD

Blood (2004) 104 (11): 345.

https://doi.org/10.1182/blood.V104.11.345.345

Published: 2004

NARROW

Puma Is The Critical BH3-Only Protein Mediating Apoptosis In The Nup98-HoxD13 (NHD13) Mouse Model Of Human MDS

Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model

Knock-in of a FLT3 Internal Tandem Duplication Mutation Cooperates with a NUP98-HOXD13 Fusion to Generate Acute Myeloid Leukemia

Enforced Expression of Lin28b Drives Development of Peripheral T Cell Lymphoma In Vivo

Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice

Knock-in of a FLT3 Internal Tandem Duplication Mutation Cooperates with a NUP98-HOXD13 Fusion to Generate Acute Leukemia in a Mouse Model.

Identification of Genes That Collaborate with CALM-AF10 to Induce Leukemia by Retroviral Insertional Mutagenesis and Candidate Gene Sequencing

Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras , Kras , and Cbl

A NUP98-HOXD13 Fusion Gene Induces a Transplantable Myelodysplastic Syndrome in Mice.

A NUP98-HOXD13 Fusion Gene Impairs Differentiation of T and B Lymphocytes.

Leukemic Transformation in Mice Expressing a NUP98-HOXD13 Transgene Is Accompanied by Spontaneous Mutations in Receptor Tyrosine Kinase Pathway Genes.

Retroviral Insertion Tagging Identifies Mn1 as a Specific Collaborator of NUP98 - HOXD13 in a Murine Model of Leukemogenesis.

Acceleration of Leukemogenesis in NUP98-HOXD13 Transgenic Mice by Infection with the MOL4070LTR Virus, and Identification of Collaborating Genes.

NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia

NUP98-HOXD13 Transgenic Mice Develop Myelodysplastic Syndrome, Acute Myeloid Leukemia, and Pre-T Lymphoblastic Leukemia.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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