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Journal Articles

Comparing Phenotyping, Gene Expression, and Function of T Lymphocytes before Mobilization Chemotherapy Versus after Stem Cell Harvesting in Patients with B Cell Lymphoma and Multiple Myeloma

Sheng-Hsuan Chien, Xiuli Wang, Wen-Chun Chen, Chun-Yu Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 2147.
https://doi.org/10.1182/blood-2023-173443
Published: 2023
Journal Articles

The Kinetics of FLT3L during Induction Chemotherapy for Pediatric Acute Lymphoblastic Leukemia Suggests a Novel Clinical Diagnostic and Treatment Strategy

Wenqing Wang, Yan-lai Tang, Zhen Li, Hao Jiang, Chi-Kong Li, Chun Chen, Yun Chen, Hongman Xue
Journal: Blood
Blood (2023) 142 (Supplement 1): 5823.
https://doi.org/10.1182/blood-2023-187653
Published: 2023
Journal Articles

Niclosamide Inhibits the Growth of Acute Lymphoblastic Leukemia Cells By Increasing Intracellular ROS and Activation of p53-PUMA/NOXA

Junbin Huang, Jing Yang, Yun Chen, Zhizhuang Joe Zhao, Chun Chen
Journal: Blood
Blood (2022) 140 (Supplement 1): 5917.
https://doi.org/10.1182/blood-2022-168825
Published: 2022
Journal Articles

Screening of Differential DNA Methylation Sites and Signal Pathway Analysis of Juvenile Myelomonocytic Leukemia in Children before and after Decitabine Treatment

Junbin Huang, Zhiyong Peng, Chunfu Li, Chun Chen
Journal: Blood
Blood (2022) 140 (Supplement 1): 11736–11737.
https://doi.org/10.1182/blood-2022-168428
Published: 2022
Journal Articles

Aurora Kinase B/C Inhibitor GSK1070916 Specifically Targets Juvenile Myelomonocytic Leukemia Cells with SHP2(PTPN11) Mutation

Chunxiao He, Dengyang Zhang, Yao Guo, Yuming Zhao, Junbin Huang, Hongman Xue, Chun Chen, Yun Chen, Zhizhuang Joe Zhao
Journal: Blood
Blood (2022) 140 (Supplement 1): 3092.
https://doi.org/10.1182/blood-2022-168468
Published: 2022
Journal Articles

Establishment of Stable Cell Lines Representing Juvenile Myelomonocytic Leukemia with SHP2 Mutations

Yuming Zhao, Yao Guo, Chunxiao He, Dengyang Zhang, Han Zhong Pei, Ming Yang, Zhiguang Chang, Liuting Yu, Junbin Huang, Hongman Xue, Chun Chen, Zhizhuang Joe Zhao, Yun Chen
Journal: Blood
Blood (2021) 138 (Supplement 1): 4353.
https://doi.org/10.1182/blood-2021-150007
Published: 2021
Journal Articles

Small Molecule Kinase Inhibitor Sunitinib Specifically Targets Juvenile Myelomonocytic Leukemia Cells with SHP2(PTPN11) Mutation

Chunxiao He, Yuming Zhao, Junbin Huang, Yao Guo, Hongman Xue, Chun Chen, Yun Chen, Zhizhuang Joe Zhao
Journal: Blood
Blood (2021) 138 (Supplement 1): 3353.
https://doi.org/10.1182/blood-2021-149324
Published: 2021
Journal Articles

Insufficient Phosphorylation of STAT5 in Tregs Inhibits the Expression of BLIMP-1, Leading to a Lack of Tregs in Pediatric Aplastic Anemia

Lifen Huang, Junbin Huang, Chengming Zhu, Hongman Xue, Chi Kong Li, Chun Chen
Journal: Blood
Blood (2021) 138 (Supplement 1): 2183.
https://doi.org/10.1182/blood-2021-152339
Published: 2021
Journal Articles

FLT3 Ligand-DM1 Conjugate Selectively Targets Acute Myeloid Leukemia Cells with FLT3 Expression

Dengyang Zhang, PhD, Yao Guo, PhD, Yuming Zhao, MD, Liuting Yu, Zhiguang Chang, PhD, Han Zhong Pei, Junbin Huang, MDPhD, Chun Chen, MDPhD, Hongman Xue, MDPhD, Yihang Pan, MD, Ningning Li, PhD, Chengming Zhu, PhD, Zhizhuang Joe Zhao, PhD, Jian Yu, PhD, Yun Chen, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-140200
Published: 2020
Journal Articles

Tumor Associated Macrophages Express High-Levels of FLT3 Ligand, Which Induces Activation of FLT3 Signaling That Promotes Survival of Neoplastic Cells in B-Cell Acute Lymphoblastic Leukemia

Yao Guo, PhD, Junbin Huang, MDPhD, Dengyang Zhang, PhD, Liqin Zhang, Yuming Zhao, Liuting Yu, Zhiguang Chang, PhD, Han Zhong Pei, Chun Chen, MDPhD, Hongman Xue, MDPhD, Xiaojun Xu, MDPhD, Zhizhuang Joe Zhao, PhD, Yun Chen, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 36–37.
https://doi.org/10.1182/blood-2020-142093
Published: 2020
Journal Articles

The Impact of HLA Mismatch Direction on the Outcome of Allogeneic Hematopoietic Stem Cell Transplantation in AML Patients

Wen-Chun Chen, MD, Jyh-Pyng Gau, Sr., MD, Liang-Tsai Hsiao, MD PhD, Chia-Jen Liu, MD, Yao-Chung LIU, MD, Hao-Yuan Wang, MD, Po-Shen Ko, MD, Jin-Hwang Liu, MD PhD, Tzeon-Jye Chiou, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4608.
https://doi.org/10.1182/blood-2019-125179
Published: 2019
Journal Articles

Clinical Outcome of Pediatric Acquired Aplastic Anemia Underwent Immunosuppressive Therapy and Transplantation: A 13-Year Experience in Two Tertiary Care Centers , Southern China

Junbin Huang, Lifeng Huang, Su Liu, Yucai Cheng, Hongman Xue, Chun Chen, Shaofen Lin
Journal: Blood
Blood (2019) 134 (Supplement_1): 5022.
https://doi.org/10.1182/blood-2019-128617
Published: 2019
Journal Articles

Identification of a Novel Indel Mutation in GATA-1 Gene In Vivo and Verified Its Defective Function in Vitro

Junbin Huang, Lifeng Huang, Yingsi Lu, Chengming Zhu, Chun Chen
Journal: Blood
Blood (2019) 134 (Supplement_1): 4801.
https://doi.org/10.1182/blood-2019-126762
Published: 2019
Journal Articles

Metabolic Alterations May Contribute to Cabozantinib Resistance in Acute Myeloid Leukemia Cells with FLT3 -ITD

Fang-Yu Lo, Kit Man Ng, MS, Wen-Chun Chen, MS, Chung-Yi Hu, PhD, Hsin-An Hou, MD PhD, Cheng-Hong Tsai, MD, M.Sc., Da-Liang Ou, PhD, Hwei-Fang Tien, MD, PhD, Liang-In Lin, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2785.
https://doi.org/10.1182/blood-2018-99-118322
Published: 2018
Journal Articles

A Multicenter Nonrandom Clinical Study of Induction Regimen of FLAG-ID and Dae in the Treatment of Childhood De Novo Acute Myeloid Leukemia in South of China:the Early Report of Efficacy and Safety

Jian Li, MD, Chunfu Li, MD, Hua Jiang, MD, Mincui Zheng, Xiangling He, Honggui Xu, Chun Chen, Hong Wen, Changgang Li, MD, Xiaoqin Feng, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3873.
https://doi.org/10.1182/blood.V130.Suppl_1.3873.3873
Published: 2017
Journal Articles

Standardized Targeted Sequencing of 29 Genes with Recurrent Mutations in Chronic Lymphocytic Leukemia (CLL) Helps to Better Define Clinical Correlates and Genomic Hotspots

Boyu Hu, MD, Keyur Patel, MD PhD, Xuemei Wang, Hsiang-Chun Chen, PhD, Philip A Thompson, MBBS, Michael J. Keating, MD, Jan A. Burger, MD PhD, Nitin Jain, MD, Alessandra Ferrajoli, MD, Prithviraj Bose, MD, Zeev Estrov, MD, Raja Luthra, Mark Routbort, MD PhD, Rashmi Kanagal-Shamanna, MD, L. Jeffrey Medeiros, MD, C. Cameron Yin, MD PhD, Zhuang Zuo, Chi Young Ok, MD, Sanam Loghavi, MD, William G Wierda, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4304.
https://doi.org/10.1182/blood.V130.Suppl_1.4304.4304
Published: 2017
Journal Articles

Inhibition of Oxphos with Iacs-010759 Depletes AML Leukemia Initiating Cells (LIC) in Vitro and Improves Survival in Pre-Clinical AML Models

Natalia Baran, PhD MD, Lina Han, PhD, Shannon Renee Sweeney, MS, Alessia Lodi, PhD, Shelley Herbrich, MS, Antonio Cavazos, MSc, Helen Ma, MS, Jason P Gay, MS, Ningping Feng, PhD, Hsiang-Chun Chen, PhD, Marcin Kaminski, PhD, Kenneth Dunner, Jr., AS, BS, Guilin Tang, MD, Gheath Alatrash, DO, PhD, Jennifer Molina, PhD, Monica L. Guzman, PhD, Jing Ning, PhD, Stefano Tiziani, PhD, Joseph R Marszalek, PhD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1350.
https://doi.org/10.1182/blood.V130.Suppl_1.1350.1350
Published: 2017
Journal Articles

Archetypes of AML Defined Using Whole Exome Sequencing and Clinical Characteristics in a Diverse Group of Patients

Christopher B. Benton, MD, Koichi Takahashi, MD, Prithviraj Bose, MD, Feng Wang, PhD, Hsiang-Chun Chen, Xiaofeng Zheng, Jianhua Zhang, Xuemei Wang, MS, Xiaoping Su, PhD, Guillermo Montalban-Bravo, MD, Ghayas C. Issa, MD, Naval Daver, MD, Elias J. Jabbour, MD, Courtney D DiNardo, MD, Carlos E Bueso-Ramos, MD PhD, Keyur Patel, MD, Steven M. Kornblau, MD, Marina Konopleva, MD PhD, Gautam Borthakur, MD, Tapan M. Kadia, MD, Jorge E. Cortes, MD, Farhad Ravandi, MD, Michael Andreeff, MD PhD, Guillermo Garcia-Manero, MD, Andrew Futreal, PhD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2016) 128 (22): 597.
https://doi.org/10.1182/blood.V128.22.597.597
Published: 2016
Journal Articles

A Phase II Clinical Trial of Azacitidine and Vorinostat for Patients with Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS) with Poor Performance Status, Comorbidities, Other Active Malignancies or Organ Dysfunction Not Eligible for Conventional Clinical Trials

Guillermo Montalban-Bravo, MD, Xuelin Huang, PhD, Elias J. Jabbour, MD, Gautam Borthakur, MD, Courtney D. DiNardo, MD MSCE, Naveen Pemmaraju, MD, Jorge E. Cortes, MD, Srdan Verstovsek, MD PhD, Tapan M. Kadia, MD, Naval G. Daver, MD, William G. Wierda, MD PhD, Yesid Alvarado, MD, Marina Konopleva, MD PhD, Farhad Ravandi, MD, Zeev Estrov, MD, Nitin Jain, MD, Ana Alfonso Pierola, MD PhD, Mark Brandt, BS, Troy Sneed, Hsiang-Chun Chen, Hui Yang, MD PhD, Carlos E Bueso-Ramos, MD PhD, Sherry Pierce, BSN, BA, Elihu H. Estey, MD, Zachary S. Bohannan, MA, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2016) 128 (22): 1999.
https://doi.org/10.1182/blood.V128.22.1999.1999
Published: 2016
Journal Articles

Allogeneic Hematopoietic Stem Cell Transplantation (HCT) in First Remission Improves Outcome Irrespective of FLT3-ITD Allelic Burden Among Patients with Acute Myeloid Leukemia and FLT3-ITD Mutation

Betul Oran, MD, Richard E. Champlin, Jorge E. Cortes, Marcos de Lima, MD, Xuemei Wang, PhD, Hsiang-Chun Chen, Farhad Ravandi, MD, Stefan O. Ciurea, MD, Hagop M. Kantarjian, MD, Gautam Borthakur, MD
Journal: Blood
Blood (2014) 124 (21): 2531.
https://doi.org/10.1182/blood.V124.21.2531.2531
Published: 2014