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Journal Articles

AICAR Induces Apoptosis In B Lymphocytes From Balb/c Mice and Its Effect In Chronic Lymphocytic Leukemia Cells Is Synergic or Additive with Current Chemotherapy

Diana M González-Gironès, Antonio F Santidrián, Daniel Iglesias-Serret, Ana M Cosialls, Alba Pérez-Perarnau, Camila Rubio-Patiño, Mercè de Frias, Alberto Fernandez de Sevilla, MD, PhD, Eva González-Barca, Esmeralda de la Banda, Gabriel Pons, Clara Campàs, Joan Gil
Journal: Blood
Blood (2010) 116 (21): 1815.
https://doi.org/10.1182/blood.V116.21.1815.1815
Published: 2010
Journal Articles

Acadesine Inhibits Proliferation and Induces Apoptosis In Multiple Myeloma Cells, and Synergizes with Standard of Care Antimyeloma Agents

Susana Hernández-García, Mercè de Frias, Clara Campàs, Bruno Paiva, Enrique M. Ocio, Jesús F. San Miguel, Sr., MD, PhD, Atanasio Pandiella, Sr., MD, PhD
Journal: Blood
Blood (2010) 116 (21): 5023.
https://doi.org/10.1182/blood.V116.21.5023.5023
Published: 2010
Journal Articles

The Nucleoside Analogue Acadesine Exerts Antitumoral Activity and Cooperates with Conventional Agents In In Vitro and In Vivo Models of Mantle Cell Lymphoma

Arnau Montraveta, MS, Mercè de Frías, PhD, Clara Campàs, PhD, Elias Campo, MD, PhD, Gael Roue, PhD, Dolors Colomer, PhD
Journal: Blood
Blood (2010) 116 (21): 3918.
https://doi.org/10.1182/blood.V116.21.3918.3918
Published: 2010
Journal Articles

Acadesine for Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL): A Multicentre Phase I/II Study

Eric Van den Neste, Bruno Cazin, Ann Janssens, M.D., Eva González-Barca, María José Terol, Vincent Levy, Jaime Pérez de Oteyza, Pierre Zachee, Andrew Saunders, Mercè de Frias, Clara Campàs
Journal: Blood
Blood (2010) 116 (21): 4625.
https://doi.org/10.1182/blood.V116.21.4625.4625
Published: 2010
Journal Articles

Acadesine-Induced Citotoxicy In Chronic Lymphocytic Leukemia Is Independent of Immunoglobulin Mutational Status and Zap70 Expression

Silvia Pairet, Ana Ferrer, Eugenia Abella, MariCarmen Vela, Raquel Longarón, Clara Campàs, Mercè de Frías, Aina Pons, Blanca Espinet, Sergi Serrano, Carlos Besses, Beatriz Bellosillo
Journal: Blood
Blood (2010) 116 (21): 4631.
https://doi.org/10.1182/blood.V116.21.4631.4631
Published: 2010
Journal Articles

AICAR Induces Apoptosis in Chronic Lymphocytic Leukemia Cells through the Mitochondrial Pathway and Independently of p53 Pathway and AMPK Activation.

Joan Gil, PhD, Antonio F Santidrián, PhD, Diana M González-Gironès, PhD, Daniel Iglesias-Serret, PhD, Llorenç Coll-Mulet, PhD, Ana M Cosialls, PhD, Mercè de Frias, PhD, Clara Campàs, PhD, Eva González-Barca, MD, PhD, Esther Alonso, MD, Alberto Fernandez de Sevilla, MD, PhD, Benoit Viollet, PhD, Gabriel Pons, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 4819.
https://doi.org/10.1182/blood.V114.22.4819.4819
Published: 2009
Journal Articles

MDM2 antagonists activate p53 and synergize with genotoxic drugs in B-cell chronic lymphocytic leukemia cells

Llorenç Coll-Mulet, Daniel Iglesias-Serret, Antonio F. Santidrián, Ana M. Cosialls, Mercè de Frias, Esther Castaño, Clara Campàs, Montserrat Barragán, Alberto Fernández de Sevilla, Alicia Domingo, Lyubomir T. Vassilev, Gabriel Pons, Joan Gil
Journal: Blood
Blood (2006) 107 (10): 4109–4114.
https://doi.org/10.1182/blood-2005-08-3273
Published: 2006
Includes: Supplemental data
Journal Articles

MDM2 Antagonists Activate p53 and Synergize with Genotoxic Drugs To Induce Apoptosis in B-Cell Chronic Lymphocytic Leukemia Cells but Not in T Cells.

Joan Gil, PhD, Llorenç Coll-Mulet, BD, Daniel Iglesias-Serret, PhD, Antonio F. Santidrián, BD, Esther Castaño, PhD, Clara Campàs, PhD, Montserrat Barragán, PhD, Ana M. Cosialls, BD, Mercé De Frias, BD, Alberto Fernández de Sevilla, MD, PhD, Alicia Domingo, MD, Lyubomir T. Vassilev, PhD, Gabriel Pons, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 5040.
https://doi.org/10.1182/blood.V106.11.5040.5040
Published: 2005
Journal Articles

Mechanism of Acadesine-Induced Apoptosis in B-Cell Neoplasms.

Antonio F. Santidrián, BD, Clara Campàs, PhD, Llorenç Coll-Mulet, BD, Daniel Iglesias-Serret, PhD, Ana M. Cosialls, BD, Mercé Defrias, BD, Alicia Domindo, MD, Alberto Fernandez de Sevilla, MD, PhD, Gabriel Pons, MD, PhD, Joan Gil, PhD
Journal: Blood
Blood (2005) 106 (11): 4822.
https://doi.org/10.1182/blood.V106.11.4822.4822
Published: 2005
Journal Articles

Acadesine activates AMPK and induces apoptosis in B-cell chronic lymphocytic leukemia cells but not in T lymphocytes

Clara Campàs, José Manuel López, Antonio F. Santidrián, Montserrat Barragán, Beatriz Bellosillo, Dolors Colomer, Joan Gil
Journal: Blood
Blood (2003) 101 (9): 3674–3680.
https://doi.org/10.1182/blood-2002-07-2339
Published: 2003
Journal Articles

Involvement of protein kinase C and phosphatidylinositol 3–kinase pathways in the survival of B-cell chronic lymphocytic leukemia cells

Montserrat Barragán, Beatriz Bellosillo, Clara Campàs, Dolors Colomer, Gabriel Pons, Joan Gil
Journal: Blood
Blood (2002) 99 (8): 2969–2976.
https://doi.org/10.1182/blood.V99.8.2969
Published: 2002