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Journal Articles

Preclinical Determination of the Efficacy of Epigenetic Therapy in High Risk Myeloid Disease Using the Zebrafish Model

Adam Deveau, BSc, MSc, Alexander Michael Forrester, BSc, PhD, Andrew J Coombs, BScH, Gretchen S Wagner, BScH, Clemens Grabher, PhD, Ian Chute, MSc, Daniel Leger, MSc, Stephen Lewis, PhD, Matthew Mingay, BSc, Martin Hirst, PhD, A. Thomas Look, MD, Jason N. Berman, MD

Blood (2014) 124 (21): 436.

https://doi.org/10.1182/blood.V124.21.436.436

Published: 2014

Journal Articles

Epigenetic Therapy Inhibits NUP98-HOXA9 -Mediated Myeloid Disease – Decitabine and Valproic Acid Work Synergistically to Rescue Normal Hematopoiesis in Transgenic Zebrafish.

Adam Deveau, BSc(Hons), A. Michael Forrester, PhD, Clemens Grabher, Andrew J Coombs, BSc(Hon), Ian Chute, MSc, Daniel Leger, MSc, Stephen Lewis, PhD, A. Thomas Look, M.D., Jason N Berman, MD

Blood (2012) 120 (21): 2391.

https://doi.org/10.1182/blood.V120.21.2391.2391

Published: 2012

Journal Articles

NUP98-HOXA9 drives High-Risk Myeloid Disease in Zebrafish – An In Vivo platform to Study Interacting Genes and Perform Drug Discovery,

A. Michael Forrester, BSc(Hon), Andrew J Coombs, BSc(Hon), Eileen R McBride, MD, FRCP(C), Ian Chute, MSc, Daniel Leger, MSc, Stephen Lewis, PhD, Clemens Grabher, PhD, Thomas Look, MD, Jason N Berman, MD

Blood (2011) 118 (21): 3622.

https://doi.org/10.1182/blood.V118.21.3622.3622

Published: 2011

Journal Articles

Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish

Niccolò Bolli, Elspeth M. Payne, Clemens Grabher, Jeong-Soo Lee, Adam B. Johnston, Brunangelo Falini, John P. Kanki, A. Thomas Look

Blood (2010) 115 (16): 3329–3340.

https://doi.org/10.1182/blood-2009-02-207225

Published: 2010

Includes: Supplemental data

Journal Articles

NUP98-HOXA9 Reprograms Embryonic Hematopoiesis, Suppresses Cellular Apoptosis, and Causes Malignant Tissue Infiltrates in Transgenic Zebrafish.

A. Michael Forrester, BSc(hons), Ellen R. Boyd, BSc(hons), Clemens Grabher, PhD, Eileen R. McBride, MD, Sahar Da'as, MSc, Fui Boon Kai, BSc(hons), A. Thomas Look, MD, Jason N. Berman, MD

Blood (2009) 114 (22): 3961.

https://doi.org/10.1182/blood.V114.22.3961.3961

Published: 2009

Journal Articles

Oncogenic HOXA9 Inhibits Cellular Apoptosis Induced by Ionizing Radiation (IR) in Transgenic Zebrafish

Ellen R Boyd, A. Michael Forrester, BSc(Hon), Clemens Grabher, PhD, Fui Boon Kai, BSc(Hon), Sahar Daas, MSc, A. Thomas Look, MD, Jason N Berman, MD

Blood (2008) 112 (11): 5325.

https://doi.org/10.1182/blood.V112.11.5325.5325

Published: 2008

Journal Articles

Human Nucleophosmin (NPM1) Perturbs Myeloid Development in Zebrafish in Vivo

Niccolò Bolli, MD, Elspeth Payne, MB, BSc, MRCP, Clemens Grabher, PhD, Adam Johnston, AB, John Kanki, PhD, A. Thomas Look, MD

Blood (2008) 112 (11): 308.

https://doi.org/10.1182/blood.V112.11.308.308

Published: 2008

Journal Articles

C-Myc- Dependent Stabilization of Hif-1alpha in MM: Therapeutic Implications

Klaus Podar, MD, MSc, PhD, Jing Zhang, MS, Giovanni Tonon, MD, PHD, Clemens Grabher, MSc, PHD, Samir Lababidi, PHD, Marc S Raab, MD, Sonia Vallet, MD, Yiming Zhou, PHD, Marie-Astrid Cartron, MS, Martin Sattler, PhD, Dharminder Chauhan, JD, PHD, Kenneth C Anderson, MD

Blood (2008) 112 (11): 2750.

https://doi.org/10.1182/blood.V112.11.2750.2750

Published: 2008

Journal Articles

The Role of RNA Helicase Dead Box 18 in Zebrafish Hematopoiesis and Human MDS

Elspeth Payne, MB, ChB, Niccolo Bolli, MD, Clemens Grabher, Jennifer Rhodes, PhD, John Kanki, Ilene Galinsky, ANP, Richard Stone, MD, Finbar E Cotter, FRCP, FRCPath, PhD, A. Thomas Look, MD

Blood (2008) 112 (11): 500.

https://doi.org/10.1182/blood.V112.11.500.500

Published: 2008

Journal Articles

Function of Nucleophosmin in Zebrafish Hematopoiesis.

Elspeth M. Payne, MB, ChB, Clemens Grabher, PhD, Niccolo Bolli, MD, John Kanki, PhD, Brunangelo Falini, MD, A. Thomas Look, MD

Blood (2007) 110 (11): 2644.

https://doi.org/10.1182/blood.V110.11.2644.2644

Published: 2007

NARROW

Preclinical Determination of the Efficacy of Epigenetic Therapy in High Risk Myeloid Disease Using the Zebrafish Model

Epigenetic Therapy Inhibits NUP98-HOXA9 -Mediated Myeloid Disease – Decitabine and Valproic Acid Work Synergistically to Rescue Normal Hematopoiesis in Transgenic Zebrafish.

NUP98-HOXA9 drives High-Risk Myeloid Disease in Zebrafish – An In Vivo platform to Study Interacting Genes and Perform Drug Discovery,

Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish

NUP98-HOXA9 Reprograms Embryonic Hematopoiesis, Suppresses Cellular Apoptosis, and Causes Malignant Tissue Infiltrates in Transgenic Zebrafish.

Oncogenic HOXA9 Inhibits Cellular Apoptosis Induced by Ionizing Radiation (IR) in Transgenic Zebrafish

Human Nucleophosmin (NPM1) Perturbs Myeloid Development in Zebrafish in Vivo

C-Myc- Dependent Stabilization of Hif-1alpha in MM: Therapeutic Implications

The Role of RNA Helicase Dead Box 18 in Zebrafish Hematopoiesis and Human MDS

Function of Nucleophosmin in Zebrafish Hematopoiesis.

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American Society of Hematology

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American Society of Hematology

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