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Daniel Ricklin
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Journal Articles

Incomplete inhibition by eculizumab: mechanistic evidence for residual C5 activity during strong complement activation

Markus J. Harder, Nadine Kuhn, Hubert Schrezenmeier, Britta Höchsmann, Inge von Zabern, Christof Weinstock, Thomas Simmet, Daniel Ricklin, John D. Lambris, Arne Skerra, Markus Anliker, Christoph Q. Schmidt
Journal: Blood
Blood (2017) 129 (8): 970–980.
https://doi.org/10.1182/blood-2016-08-732800
Published: 2017
Includes: Supplemental data
Journal Articles

Complement C3dg-mediated erythrophagocytosis: implications for paroxysmal nocturnal hemoglobinuria

Brief Report
Zhuoer Lin, Christoph Q. Schmidt, Sophia Koutsogiannaki, Patrizia Ricci, Antonio M. Risitano, John D. Lambris, Daniel Ricklin
Journal: Blood
Blood (2015) 126 (7): 891–894.
https://doi.org/10.1182/blood-2015-02-625871
Published: 2015
Includes: Supplemental data
Journal Articles

Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria

Antonio M. Risitano, Daniel Ricklin, Yijun Huang, Edimara S. Reis, Hui Chen, Patrizia Ricci, Zhuoer Lin, Caterina Pascariello, Maddalena Raia, Michela Sica, Luigi Del Vecchio, Fabrizio Pane, Florea Lupu, Rosario Notaro, Ranillo R. G. Resuello, Robert A. DeAngelis, John D. Lambris
Journal: Blood
Blood (2014) 123 (13): 2094–2101.
https://doi.org/10.1182/blood-2013-11-536573
Published: 2014
Includes: Supplemental data
Journal Articles

Preclinical Development and In Vivo Evaluation Of Next-Generation Compstatin Analogs With Improved Systemic Profiles: A Novel Option For The Treatment Of Paroxysmal Nocturnal Hemoglobinuria

Daniel Ricklin, Ph.D., Antonio M. Risitano, MD, PhD, Edimara S. Reis, Ph.D., Patrizia Ricci, Yijun Huang, Ph.D., Zhuoer Lin, Ph.D., Hui Chen, Ph.D., Caterina Pascariello, Maddalena Raia, Luigi Del Vecchio, MD, Fabrizio Pane, MD, Ranillo R. G. Resuello, D.V.M., Robert A. DeAngelis, Ph.D., John D. Lambris, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 1239.
https://doi.org/10.1182/blood.V122.21.1239.1239
Published: 2013
Journal Articles

TMA: beware of complements

Daniel Ricklin, Douglas B. Cines
Journal: Blood
Blood (2013) 122 (12): 1997–1999.
https://doi.org/10.1182/blood-2013-07-512707
Published: 2013
Journal Articles

Novel Complement Modulators for Paroxysmal Nocturnal Hemoglobinuria: Peptide and Protein Inhibitors of C3 Convertase Prevent Both Surface C3 Deposition and Subsequent Hemolysis of Affected Erythrocytes in Vitro

Antonio M. Risitano, MD, PhD, Patrizia Ricci, Caterina Pascariello, Maddalena Raia, Christoph Q Schmidt, Yingxue Li, Edimara S Reis, Michela Sica, PhD, Rosario Notaro, MD, Luigi Del Vecchio, MD, Fabrizio Pane, Daniel Ricklin, John D Lambris
Journal: Blood
Blood (2012) 120 (21): 370.
https://doi.org/10.1182/blood.V120.21.370.370
Published: 2012