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Journal Articles

RNAi Screening of the Human Kinome Identifies Inhibition of WEE1 Kinase As Potent and Universal Sensitizing Target to Cytarabine in Leukemias

Raoul Tibes, MD, PhD, Leena Chaudhuri, PhD, James M Bogenberger, PhD, Tanner R Hagelstrom, PhD, MBA, Amanda McNally, MS, Donald Chow, Megan E Buechel, MS, Irma Gonzales, Esteban Braggio, PhD, Hongwei Yin, PHD, Shilpi Arora, PhD, David Azorsa, PhD, Craig B. Reeder, MD, Pierre Noel, MD, James L. Slack, MD, Ruben A. Mesa, MD, Tim Demuth, MD, PhD

Blood (2011) 118 (21): 229.

https://doi.org/10.1182/blood.V118.21.229.229

Published: 2011

Journal Articles

RNAi Screening Identifies BCL-XL As An Erythroid Lineage-Specific 5-Azacytidine Sensitizer While the BCL-2/BCL-XL/BCL-W Inhibitor ABT-737 Results in More Universal Sensitization in Leukemia Cells,

James M Bogenberger, PhD, Chang-Xin Shi, Irma Gonzales, Rodger E. Tiedemann, MBChB, PhD, FRACP, FRCPA, Pierre Noel, MD, James L. Slack, MD, Ruben A. Mesa, MD, Keith Stewart, MBA, MB, CHB, Yihua Qiu, Kevin R Coombes, Steven M. Kornblau, MD, David Azorsa, PhD, Raoul Tibes, MD, PhD

Blood (2011) 118 (21): 3513.

https://doi.org/10.1182/blood.V118.21.3513.3513

Published: 2011

Journal Articles

Phosphatome and Kinome RNAi Screen In Leukemia

Raoul Tibes, James Bogenberger, Donald Chow, Irma Gonzales, David Azorsa, Holly Yin

Blood (2010) 116 (21): 180.

https://doi.org/10.1182/blood.V116.21.180.180

Published: 2010

Journal Articles

Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6

Rodger E. Tiedemann, Yuan Xiao Zhu, Jessica Schmidt, Hongwei Yin, Chang-Xin Shi, Qiang Que, Gargi Basu, David Azorsa, Louise M. Perkins, Esteban Braggio, Rafael Fonseca, P. Leif Bergsagel, Spyro Mousses, A. Keith Stewart

Blood (2010) 115 (8): 1594–1604.

https://doi.org/10.1182/blood-2009-09-243980

Published: 2010

Includes: Supplemental data

Journal Articles

Kinome-Wide RNAi Studies in Human Multiple Myeloma Identify a Lymphoid Restricted Kinase GRK6 as a Selectively Vulnerable Target That Regulates STAT3/MCL1.

Rodger E. Tiedemann, MBChB, PhD, FRACP, FRCPA, Yuan Xiao Zhu, Jessica Schmidt, BS, Hongwei Yin, PhD, Quick Que, PhD, David Azorsa, PhD, Louise M. Perkins, PhD, Esteban Braggio, PhD, Craig B. Reeder, MD, Rafael Fonseca, MD, P. Leif Bergsagel, MD, Spyro Mousses, PhD, A. Keith Stewart, MD

Blood (2009) 114 (22): 601.

https://doi.org/10.1182/blood.V114.22.601.601

Published: 2009

Journal Articles

RNAi-Based Functional Genomics Screening of the Human Kinome Identifies Major Growth Regulating Kinases in Acute Myeloid Leukemia Cells

Raoul Tibes, MD, PhD, Ashish Choudhary, PhD, Amanda Henrichs, BS, Sadia Guled, BS, Irma Monzon, BS, Lourdes Peralta, BS, Jeff Kiefer, PhD, David Azorsa, PhD

Blood (2008) 112 (11): 2951.

https://doi.org/10.1182/blood.V112.11.2951.2951

Published: 2008

Journal Articles

Identification of Sensitizing Targets to the Hypomethylating Agent 5-Azacytidine in Acute Myeloid Leukemia Cells Using RNAi-Based Functional Genomics Screening

Raoul Tibes, MD, PhD, Ashish Choudhary, PhD, Amanda Henrichs, BS, Sadia Guled, BS, Irma Monzon, BS, Lourdes Peralta, BS, Spyro Mousses, PhD, David Azorsa, PhD

Blood (2008) 112 (11): 2665.

https://doi.org/10.1182/blood.V112.11.2665.2665

Published: 2008

NARROW

RNAi Screening of the Human Kinome Identifies Inhibition of WEE1 Kinase As Potent and Universal Sensitizing Target to Cytarabine in Leukemias

RNAi Screening Identifies BCL-XL As An Erythroid Lineage-Specific 5-Azacytidine Sensitizer While the BCL-2/BCL-XL/BCL-W Inhibitor ABT-737 Results in More Universal Sensitization in Leukemia Cells,

Phosphatome and Kinome RNAi Screen In Leukemia

Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6

Kinome-Wide RNAi Studies in Human Multiple Myeloma Identify a Lymphoid Restricted Kinase GRK6 as a Selectively Vulnerable Target That Regulates STAT3/MCL1.

RNAi-Based Functional Genomics Screening of the Human Kinome Identifies Major Growth Regulating Kinases in Acute Myeloid Leukemia Cells

Identification of Sensitizing Targets to the Hypomethylating Agent 5-Azacytidine in Acute Myeloid Leukemia Cells Using RNAi-Based Functional Genomics Screening

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ASH Publications

American Society of Hematology

RNAi Screening of the Human Kinome Identifies Inhibition of WEE1 Kinase As Potent and Universal Sensitizing Target to Cytarabine in Leukemias

RNAi Screening Identifies BCL-XL As An Erythroid Lineage-Specific 5-Azacytidine Sensitizer While the BCL-2/BCL-XL/BCL-W Inhibitor ABT-737 Results in More Universal Sensitization in Leukemia Cells,

Phosphatome and Kinome RNAi Screen In Leukemia

Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6

Kinome-Wide RNAi Studies in Human Multiple Myeloma Identify a Lymphoid Restricted Kinase GRK6 as a Selectively Vulnerable Target That Regulates STAT3/MCL1.

RNAi-Based Functional Genomics Screening of the Human Kinome Identifies Major Growth Regulating Kinases in Acute Myeloid Leukemia Cells

Identification of Sensitizing Targets to the Hypomethylating Agent 5-Azacytidine in Acute Myeloid Leukemia Cells Using RNAi-Based Functional Genomics Screening

Email alerts

ASH Publications

American Society of Hematology

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