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David O'Brien
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Journal Articles

Minimal Residual Disease (MRD) Status in FCR-Treated CLL Patients at the End of Treatment Influences Progression Free Survival (PFS), Results of the Ctrial-IE (ICORG) 07-01/ CLL Ireland Study, with Mutational Analysis Providing Additional Insight

Niamh Appleby, FRCPath, Fiona M Quinn, PhD, David O'Brien, FAMLs, Smyth Liam, MRCPI, Johanna Kelly, BSc, Imelda Parker, Kathleen Scott, PhD, Mary R Cahill, MB, FRCPath, Gerard Crotty, Helen Enright, MD FRCPI, FRCPath, Brian Hennessy, MD MRCPI, FRCPath, Andrew Hodgson, MBBS, BSc, FRCP, FRCPath, Maeve Leahy, FRCPath, Hilary M O'Leary, FRCPath, Michael E O'Dwyer, MD, Amjad Hayat, MBBS, MRCP, MRCPath, PhD, Elisabeth A. Vandenberghe, MB, MRCPI, MRCPath, PhD
Journal: Blood
Blood (2016) 128 (22): 3237.
https://doi.org/10.1182/blood.V128.22.3237.3237
Published: 2016
Journal Articles

The Regulation of STAT3 and Its Role in the Adhesion and Migration of Chronic Lymphocytic Leukaemia Cells

Sarah Brophy, Fiona M Quinn, PhD, David O'Brien, FAMLs, Paul Browne, MD, Elisabeth A. Vandenberghe, MB, PhD, Anthony M. McElligott, PhD
Journal: Blood
Blood (2016) 128 (22): 4347.
https://doi.org/10.1182/blood.V128.22.4347.4347
Published: 2016
Journal Articles

Turning the Heat up a Notch in Biclonal Lymphoproliferative Disorders

Helen Fogarty, Anita Dowling, David O'Brien, Christopher Laurence Bacon, Patrick Thornton, Brian Hennessy, MD MRCPI, FRCPath, Hilary M O'Leary, FRCPath, Gerard Crotty, Robert Henderson, James Nolan, Elisabeth A. Vandenberghe, MB, MRCPI, MRCPath, PhD, Fiona M Quinn, PhD
Journal: Blood
Blood (2016) 128 (22): 5569.
https://doi.org/10.1182/blood.V128.22.5569.5569
Published: 2016
Journal Articles

Microenvironmental-Mediated Regulation of L-Selectin in Chronic Lymphocytic Leukaemia

Sarah Brophy, Paul Browne, MD, Elisabeth A. Vandenberghe, MB, PhD, David O'Brien, FAMLs, Anthony M. McElligott, PhD
Journal: Blood
Blood (2015) 126 (23): 4133.
https://doi.org/10.1182/blood.V126.23.4133.4133
Published: 2015
Journal Articles

Detection of Mutations in SF3B1 in Chronic Lymphocytic Leukaemia Patients By Reverse Transcription (Rt) Polymerase Chain Reaction and High Resolution Melt Curve Analysis, an Alternative Approach to Next Generation Sequencing for Routine Molecular Diagnostic Laboratories?

Fiona M Quinn, PhD, Deirdre Waldron, M.Sc., David O'Brien, FAMLs, Johanna Kelly, BSc, Kathleen Scott, PhD, Amjad Hayat, MBBS, MRCP, FRCPath, PhD, Elisabeth A. Vandenberghe, MB, PhD
Journal: Blood
Blood (2015) 126 (23): 5283.
https://doi.org/10.1182/blood.V126.23.5283.5283
Published: 2015
Journal Articles

A Complementary Role of High Throughput Sequencing and Multiparameter Cytometry for Minimal Residual Disease (MRD) Detection in Chronic Lymphocytic Leukemia (CLL):an European Research Initiative (ERIC) Study

Andy Rawstron, PhD, Claudia Fazi, PhD, Neus Villamor, MD PhD, Julio Delgado, MD PhD, Remi Letestu, MD PhD, Florence Cymbalista, MD, Carlos Palacio, Francesc Bosch, MD PhD, Ruth M De Tute, MSc, Stuart Liptrot, David O'Brien, FAMLs, Martin Spacek, MD, PhD, Johan Dobber, Arnon P. Kater, MD PhD, Peter C Gambell, David A Westerman, MBBS, FRACP, FRCPA, Asha Soosapilla, Stephen P. Mulligan, MBBS, PhD FRACP, FRCPA, Gerard Lozanski, MD, Ke Lin, PhD, Andrew R Pettitt, MRCP, PhD, Gabi Brachtl, Alexander Egle, MD, David W Williamson, PhD, Catherine M Sanders, PhD, Harlan Robins, PhD, Justin Boysen, Tait D. Shanafelt, MD, Curtis A. Hanson, MD, Jeffrey L. Jorgensen, MD PhD, William G. Wierda, MD PhD, Constance Yuan, MD PhD, Maryalice Stetler-Stevenson, MD PhD, Laura Rassenti, PhD, H. Elizabeth Broome, MD, Thomas J. Kipps, MD PhD, Mathieu Hauwel, Iuri Marinov, Fiona E. Craig, MBBS, Nomdedeu Josep, Carol Moreno, MD, Olga Stehlikova, MSc., Michael Doubek, Sarka Pospisilova, Prof., Dr., PhD, Karl-Anton Kreuzer, MD, Michael Hallek, MD, Peter Hillmen, MBChB, PhD, Emili Montserrat, MD PhD, Paolo Ghia, MD
Journal: Blood
Blood (2014) 124 (21): 1976.
https://doi.org/10.1182/blood.V124.21.1976.1976
Published: 2014
Journal Articles

Minimal Residual Disease Stratification in Fludarabine Ccyclophosphamide Rituximab (FCR) Therapy in Chronic Lymphocytic Leukaemia (CLL

Amjad Hayat, MBBS, PhD, David O'Brien, Fiona Quinn, PhD, Fionnuala Keane, PhD, Imelda Parker, PhD, Johanna Kelly, BSc, Marzena Wieczorkowska, Gerard Crotty, MD, Maeve Leahy, MD, Helen Enright, MD, Brian Hennessy, MD, Mary Cahill, MB, Elisabeth A. Vandenberghe, MB, PhD
Journal: Blood
Blood (2012) 120 (21): 1791.
https://doi.org/10.1182/blood.V120.21.1791.1791
Published: 2012