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Journal Articles

Role of Mutant p53 in the Progression of Chronic Lymphocytic Leukemia

Janani Ravikrishnan, Tzung-Huei Lai, PhD DVM, Elizabeth Muhowski, Lindsey Brinton, PhD, Katie Williams, MS, Alexandria Thompson, James S. Blachly, MD, Hatice Gulcin Ozer, PhD, John C. Byrd, MD, Rosa Lapalombella, PhD, Jennifer Woyach, MD, Deepa Sampath, PhD

Blood (2019) 134 (Supplement_1): 2526.

https://doi.org/10.1182/blood-2019-128574

Published: 2019

Journal Articles

The Protein Kinase C Inhibitor MS-553 for the Treatment of Chronic Lymphocytic Leukemia

Elizabeth M. Muhowski, Amy M. Lehman, M.A.S, Sean D. Reiff, PhD, Janani Ravikrishnan, Rose Mantel, Shrilekha Misra, Michael Niesman, PhD, Kai Zhang, MD, James S. Blachly, MD, Deepa Sampath, PhD, John C. Byrd, MD, Jennifer Woyach, MD

Blood (2019) 134 (Supplement_1): 2077.

https://doi.org/10.1182/blood-2019-128871

Published: 2019

Journal Articles

Clinical and Molecular Characteristics of Acute Myeloid Leukemia (AML) Patients with TP53 Mutations and TP73 Mutations

Alice S. Mims, MD, Jessica Kohlschmidt, PhD, Ann-Kathrin Eisfeld, MD, Krzysztof Mrózek, MDPhD, James S. Blachly, MD, Shelley Orwick, BS, Dimitrios Papaioannou, MD, Deedra Nicolet, MS, Deepa Sampath, PhD, Richard M. Stone, MD, Bayard L. Powell, MD, Jonathan E. Kolitz, MD, John C. Byrd, MD, Clara D. Bloomfield, MD

Blood (2018) 132 (Supplement 1): 1488.

https://doi.org/10.1182/blood-2018-99-114704

Published: 2018

Journal Articles

NAMPT Inhibitor KPT-9274 Selectively Targets Self-Renewal Capacity in Acute Myeloid Leukemia

Shaneice Renee Mitchell, BS, Nicole Grieselhuber, MD PhD, Yerdanos Asemelash, Matthew Cannon, BA, Shelley Orwick, BS, Pratibha Sharma, PhD, Virginia Goettl, DVM, PhD, Vinay K Puduvalli, MD MBBS, Deepa Sampath, PhD, Alice S. Mims, MD, James S. Blachly, MD, Amy M. Lehman, PhD, Bonnie K. Harrington, DVM, Justin Breitbach, Erkan Baloglu, William Senapedis, PhD, Rosa Lapalombella, PhD, John C. Byrd, MD

Blood (2018) 132 (Supplement 1): 3931.

https://doi.org/10.1182/blood-2018-99-119358

Published: 2018

Journal Articles

Using HSP90 Inhibitors to Target DNA Repair Proteins in AML

Janani Ravikrishnan, BS, Tzung-Huei Lai, PhD, Shaneice Renee Mitchell, BS, Pei-Jung Wu, BS, Shelley Orwick, BS, Chaomei Liu, PhD, Jennifer A. Woyach, MD, Alice S. Mims, MD, William Plunkett, PhD, Vinay K Puduvalli, MD MBBS, John C. Byrd, MD, Rosa Lapalombella, PhD, Deepa Sampath, PhD

Blood (2018) 132 (Supplement 1): 5144.

https://doi.org/10.1182/blood-2018-99-116485

Published: 2018

Journal Articles

PRMT5 Initiates an Epigenetic Program That Promotes Progression of Chronic Lymphocytic Leukemia

Zachary A Hing, BS, Jordan N. Skinner, B.S., Larry P. Beaver, Tzung-Huei Lai, PhD, Casey B. Cempre, B.S., Bonnie K. Harrington, DVM, Deepa Sampath, PhD, Amy M. Lehman, PhD, Lianbo Yu, PhD, Lapo Alinari, MD PhD, John C. Byrd, MD, Robert A Baiocchi, MD PhD, Rosa Lapalombella, PhD

Blood (2017) 130 (Supplement 1): 2487.

https://doi.org/10.1182/blood.V130.Suppl_1.2487.2487

Published: 2017

Journal Articles

Role of Histone Deacetylase-Mediated Gene Silencing in Chronic Lymphocytic Leukemia Progression

Lara Rizzotto, PhD, Arianna Bottoni, PhD, Tzung-Huei Lai, PhD, Chaomei Liu, BS, Pearlly S Yan, PhD, Hatice G Ozer, PhD, Rosa Lapalombella, PhD, Jennifer A. Woyach, MD, Christopher C Oakes, PhD, James S. Blachly, MD, Deepa Sampath, PhD

Blood (2016) 128 (22): 2705.

https://doi.org/10.1182/blood.V128.22.2705.2705

Published: 2016

Journal Articles

Histone Deacetylase Inhibitors Induce microRNAs Targeting BTK in Acute Myeloid Leukemia

Lara Rizzotto, PhD, Tzung-Huei Lai, PhD, Chaomei Liu, BS, Arianna Bottoni, PhD, Clara D. Bloomfield, MD, John C Byrd, MD, Deepa Sampath, PhD

Blood (2015) 126 (23): 1222.

https://doi.org/10.1182/blood.V126.23.1222.1222

Published: 2015

Journal Articles

Targeting BTK By a microRNA Mechanism in Chronic Lymphocytic Leukemia

Arianna Bottoni, Rizzotto Lara, PhD, Lai Tzung-Huei, PhD, Rose Mantel, Lisa Simith, Dalia El-Gamal, PhD, Amy J. Johnson, PhD, Rosa Lapalombella, PhD, James S. Blachly, MD, John C. Byrd, MD, Jennifer A. Woyach, MD, Deepa Sampath, PhD

Blood (2015) 126 (23): 1232.

https://doi.org/10.1182/blood.V126.23.1232.1232

Published: 2015

Journal Articles

HDAC Inhibition Induces microRNA-182 Which Targets Rad51 Protein and Impairs Homologous Recombination Repair to Sensitize Cells to the Double Strand Break Inducing Nucleoside Analog, Sapacitabine in AML

Tzung-Huei Lai, PhD, Alma Zecevic, Brett Ewald, PhD, Liu Chaomei, Lara Rizzotto, PhD, Melanie Sulda, Dimitrios Papaioannou, MD, Ramiro Garzon, MD, William Plunkett, PhD, Deepa Sampath, PhD

Blood (2015) 126 (23): 3639.

https://doi.org/10.1182/blood.V126.23.3639.3639

Published: 2015

Journal Articles

The Aberrantly Expressed Long Noncoding RNA, TRERNA1, Predicts for Aggressive Disease in Chronic Lymphocytic Leukemia

Cecelia R Miller, MS, Amy S. Ruppert, MAS, Kevin Coombes, PhD, Amy M. Lehman, MAS, James S. Blachly, MD, David M. Lucas, PhD, Michael R. Grever, MD, Martin S Tallman, MD, Ian W. Flinn, MD PhD, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD PhD, Deepa Sampath, PhD, John C Byrd, MD, Erin K. Hertlein, PhD

Blood (2015) 126 (23): 2911.

https://doi.org/10.1182/blood.V126.23.2911.2911

Published: 2015

Journal Articles

Expression of PRMT5 in B-Cell Chronic Lymphocytic Leukemia and Its Significance in Disease Progression and Richter's Transformation

Dalia El-Gamal, PhD, Taylor D LaFollette, Hongshan Lai, Li Chenglong, PhD, Deepa Sampath, PhD, Amy Lehman, Lianbo Yu, John C. Byrd, MD, Robert A. Baiocchi, MD PhD, Rosa Lapalombella, PhD

Blood (2014) 124 (21): 2197.

https://doi.org/10.1182/blood.V124.21.2197.2197

Published: 2014

Journal Articles

Panobinostat, An Oral Pan-Histone Deacetylase (HDAC) Inhibitor Activates a Microrna Signature That Targets Rad51 To Attenuate Homologous DNA Repair and Sensitize AML Cells To Sapacitabine

Deepa Sampath, PhD, Alma Zecevic, PhD, Brett Ewald, PhD, Melanie Hayes, PhD, Chaomei Liu, BSc, Guido Marcucci, MD, William Plunkett, PhD

Blood (2013) 122 (21): 822.

https://doi.org/10.1182/blood.V122.21.822.822

Published: 2013

Journal Articles

Phase I Study of the Akt-Inhibitor Triciribine Phosphate Monohydrate in Patients with Advanced Hematologic Malignancy

Farhad Ravandi, MBBS, Deepa Sampath, PhD, William Plunkett, PhD, Betsy Williams, RN, Michelle Burton, RN, Srdan Verstovsek, Stefan Faderl, MD, Guillermo Garcia-Manero, MD, Vernon Alvarez, PhD, Michael D Becker, Alan F. List, MD, Said Sebti, PhD, Hagop M. Kantarjian, MD, Jeffrey Lancet, MD

Blood (2008) 112 (11): 2987.

https://doi.org/10.1182/blood.V112.11.2987.2987

Published: 2008

Journal Articles

Active Immune Gene Therapy Using ISF35: Responses Associated with Priming for Death Receptor-Induced Apoptosis and Sensitivity to Fludarabine in Patients with CLL and Del 17p

William G Wierda, MD, PhD, Januario Castro, MD, Robier A Aguillon, MD, Deepa Sampath, PhD, Annette Jalayer, RN, Charles Prussak, PhD, Michael J Keating, MBBS, Thomas J Kipps, MD, PhD

Blood (2008) 112 (11): 3530.

https://doi.org/10.1182/blood.V112.11.3530.3530

Published: 2008

NARROW

Role of Mutant p53 in the Progression of Chronic Lymphocytic Leukemia

The Protein Kinase C Inhibitor MS-553 for the Treatment of Chronic Lymphocytic Leukemia

Clinical and Molecular Characteristics of Acute Myeloid Leukemia (AML) Patients with TP53 Mutations and TP73 Mutations

NAMPT Inhibitor KPT-9274 Selectively Targets Self-Renewal Capacity in Acute Myeloid Leukemia

Using HSP90 Inhibitors to Target DNA Repair Proteins in AML

PRMT5 Initiates an Epigenetic Program That Promotes Progression of Chronic Lymphocytic Leukemia

Role of Histone Deacetylase-Mediated Gene Silencing in Chronic Lymphocytic Leukemia Progression

Histone Deacetylase Inhibitors Induce microRNAs Targeting BTK in Acute Myeloid Leukemia

Targeting BTK By a microRNA Mechanism in Chronic Lymphocytic Leukemia

HDAC Inhibition Induces microRNA-182 Which Targets Rad51 Protein and Impairs Homologous Recombination Repair to Sensitize Cells to the Double Strand Break Inducing Nucleoside Analog, Sapacitabine in AML

The Aberrantly Expressed Long Noncoding RNA, TRERNA1, Predicts for Aggressive Disease in Chronic Lymphocytic Leukemia

Expression of PRMT5 in B-Cell Chronic Lymphocytic Leukemia and Its Significance in Disease Progression and Richter's Transformation

Panobinostat, An Oral Pan-Histone Deacetylase (HDAC) Inhibitor Activates a Microrna Signature That Targets Rad51 To Attenuate Homologous DNA Repair and Sensitize AML Cells To Sapacitabine

Phase I Study of the Akt-Inhibitor Triciribine Phosphate Monohydrate in Patients with Advanced Hematologic Malignancy

Active Immune Gene Therapy Using ISF35: Responses Associated with Priming for Death Receptor-Induced Apoptosis and Sensitivity to Fludarabine in Patients with CLL and Del 17p

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American Society of Hematology

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ASH Publications

American Society of Hematology

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