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Demin Wang, PhD
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Journal Articles

Polyreactivity and Somatic Hypermutation Analysis Reveals the Innate B Cell Origin of Human PF4/Heparin Reactive Antibodies

Wen Zhu, MBBS,MS, Lu Zhou, Ting Zhao, Yongwei Zheng, PhD, Mei Yu, PhD, Jianhui Wei, Anand Padmanabhan, M.B.B.S., PhD, Richard H. Aster, MD, Demin Wang, PhD, Renren Wen, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–35.
https://doi.org/10.1182/blood-2020-138781
Published: 2020
Journal Articles

Developing Novel Targeted Therapies Using the High-Risk Vq Myeloma Model

Evan Flietner, BS, Zhi Wen, PhD, Adhithi Rajagopalan, BS, Joshua Wiesner, BS, Xiaona You, PhD, Yun Zhou, MS, Terra Lasho, PhD, Mrinal M. Patnaik, MDMBBS, Demin Wang, PhD, Robert Burns, MD, Natalie S. Callander, MD, Fotis Asimakopoulos, PhDMBBChir,, Jing Zhang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-137148
Published: 2020
Journal Articles

Plasmacytoid Dendritic Cells Surveil Megakaryocyte Sialic Acid to Regulate Thrombopoiesis

Melissa M. Lee-Sundlov, PhD, Robert Burns, PhD, Renata Grozovsky, PhD, Silvia Giannini, PhD, Leonardo Rivadeneyra, PhD, Yongwei Zheng, PhD, Simon Glabere, Walter H. Kahr, MDPhDFRCPC, Reza Abdi, Demin Wang, PhD, Karin M. Hoffmeister, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
https://doi.org/10.1182/blood-2020-142737
Published: 2020
Journal Articles

Antibody Cloning Identifies Pathogenic and Non-Pathogenic Antibodies in Heparin-Induced Thrombocytopenia and Defines the Molecular Signatures That Differentiate the Two Types of Antibodies

Wen Zhu, Yongwei Zheng, PhD, Mei Yu, PhD, Yaling Wu, Jianhui Wei, Nicholas Schneider, Anand Padmanabhan, MD PhD, Richard H. Aster, MD, Demin Wang, PhD, Renren Wen, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 439.
https://doi.org/10.1182/blood-2019-126097
Published: 2019
Journal Articles

Human Interleukin 15 (IL15) Humanized NCG Mice Support the Human Natural Killer Cells Reconstitution and Development

Cunxiang Ju, PhD, Mingkun Zhang, Dan Wu, Jing Tang, PhD, Shuai Li, Jing Zhao, PhD, Demin Wang, PhD, Xiang Gao, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4871.
https://doi.org/10.1182/blood-2019-123661
Published: 2019
Journal Articles

BALB/c-hCD3E Transgenic Mice: An Ideal Animal Model for In Vivo Efficacy Study of CD3-Bispecific Antibodies

Cunxiang Ju, PhD, Mingkun Zhang, Dongjing Jia, Jing Tang, PhD, Shuai Li, Jing Zhao, PhD, Demin Wang, PhD, Xiang Gao, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1048.
https://doi.org/10.1182/blood-2019-128781
Published: 2019
Journal Articles

Regulatory T Cells Control PF4/Heparin Antibody Production in Mice

Yongwei Zheng, Wen Zhu, Dipica Haribhai, PhD, Calvin B. Williams, PhD, Richard H. Aster, MD, Renren Wen, PhD, Demin Wang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2542.
https://doi.org/10.1182/blood-2018-99-113049
Published: 2018
Journal Articles

Critical Role of Jumonji Domain of JMJD1C in AML Leukemogenesis

Jesus Izaguirre-Carbonell, PhD, Christiansen Luke, Robert Burns, PhD, Jesse Schmitz, Chenxuan Li, Rebekah Mokry, Theresa Bluemn, Yongwei Zheng, Demin Wang, PhD, Nan Zhu, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2599.
https://doi.org/10.1182/blood-2018-99-110463
Published: 2018
Journal Articles

Mice Expressing MYC and Nras Q61R in Germinal Center B Cells Develop Highly Aggressive Multiple Myeloma

Adhithi Rajagopalan, BS, Zhi Wen, PhD, Quinlan Furumo, Erik A. Ranheim, MD PhD, Remington Finn, Evan Flietner, BS, Grant Yun, Yun Zhou, MS, Mei Yu, PhD, Natalie Scott Callander, MD, Marta Chesi, PhD, P. Leif Bergsagel, MD, Robert Burns, PhD, Demin Wang, PhD, Fotios Asimakopoulos, PhDMBBChir,, Jing Zhang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1006.
https://doi.org/10.1182/blood-2018-99-116757
Published: 2018
Journal Articles

Phospholipase Cgamma Pathway-Dependent mTOR Signaling Controls IL-7-Mediated Early B Cell Development

Mei Yu, PhD, Chen Yuhong, PhD, Hu Zeng, PhD, Yongwei Zheng, PhD, Guoping Fu, PhD, Wen Zhu, Ulrich Broeckel, MD, Praful Aggarwal, Amy Turner, Geoffrey A.M. Neale, PhD, Nan Zhu, PhD, Hongbo Chi, PhD, Renren Wen, PhD, Demin Wang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 620.
https://doi.org/10.1182/blood.V130.Suppl_1.620.620
Published: 2017
Journal Articles

Intravenous Immunoglobulin (IVIg) Is a Highly Effective Treatment for HIT: Critical Role of the IgG Fc Domain in Inhibiting HIT Antibody-Mediated Platelet Activation

Anand Padmanabhan, MBBS, MA, PhD, Curtis G Jones, Shannon M Pechauer, Barbara J. Bryant, MD, Jack B. Alperin, MD, Mehraboon S. Irani, MBBChir, Binod Dhakal, MDMS, Brian R Curtis, PhD D(ABMLI) MT(ASCP)SBB, Daniel W. Bougie, PhD, Mia J Sullivan, Renren Wen, PhD, Demin Wang, PhD, Richard H. Aster, MD
Journal: Blood
Blood (2016) 128 (22): 2600.
https://doi.org/10.1182/blood.V128.22.2600.2600
Published: 2016
Journal Articles

A Novel PF4-Dependent Platelet Activation Assay Identifies Patients Likely to Have Heparin-Induced Thrombocytopenia/Thrombosis (HIT)

Anand Padmanabhan, MBBS, MA, PhD, Curtis Jones, Brian R Curtis, MS, MT(ASCP)SBB, Daniel W. Bougie, PhD, Mia Sullivan, Namrata Peswani, MD MBBS, Janice McFarland, MD, Daniel Eastwood, Demin Wang, PhD, Richard H. Aster, MD
Journal: Blood
Blood (2015) 126 (23): 764.
https://doi.org/10.1182/blood.V126.23.764.764
Published: 2015
Journal Articles

Kras Is Critical for CD8 T Cell Antiviral Function

Yuhong Chen, PhD, Yongwei Zheng, PhD, Xiaona You, PhD, Gang Xin, PhD, Mei Yu, PhD, Guoping Fu, PhD, Fen Zhou, Wen Zhu, Weiguo Cui, PhD, Jing Zhang, PhD, Renren Wen, PhD, Demin Wang, PhD
Journal: Blood
Blood (2015) 126 (23): 284.
https://doi.org/10.1182/blood.V126.23.284.284
Published: 2015
Journal Articles

Kras Is Critical for B Cell Lymphopoiesis

Yongwei Zheng, PhD, Yuhong Chen, PhD, Xiaona You, PhD, Mei Yu, PhD, Guoping Fu, PhD, Xinlin Su, Wen Zhu, Zhihong Wu, Jing Zhang, PhD, Renren Wen, PhD, Demin Wang, PhD
Journal: Blood
Blood (2015) 126 (23): 3588.
https://doi.org/10.1182/blood.V126.23.3588.3588
Published: 2015
Journal Articles

Critical Role of T Cells in PF4/Heparin Antibody Production

Yongwei Zheng, Mei Yu, PhD, Anand Padmanabhan, MBBS, MA, PhD, Richard H. Aster, MD, Renren Wen, PhD, Demin Wang, PhD
Journal: Blood
Blood (2014) 124 (21): 1554.
https://doi.org/10.1182/blood.V124.21.1554.1554
Published: 2014
Journal Articles

Tyrosine 599 Plays an Essential Role and Cooperates with Tyrosine 604 in MPL W515L-Indiced Myeloproliferative Neoplasms

Zan Huang, Chunjie Yu, PhDcandidate, Qiang Jeremy Wen, PhD MD, Qiong Yang, John Crispino, PhD, Demin Wang, PhD, Yuhong Chen
Journal: Blood
Blood (2014) 124 (21): 4580.
https://doi.org/10.1182/blood.V124.21.4580.4580
Published: 2014
Journal Articles

Role Of B Cell Tolerance In PF4/Heparin Antibody Production

Yongwei Zheng, Alexander W Wang, Mei Yu, PhD, Anand Padmanabhan, MBBS, MA, PhD, Benjamin E Tourdot, PhD, Debra K. Newman, PhD, Gilbert C. White, II, MD, Richard H. Aster, MD, Renren Wen, PhD, Demin Wang, PhD
Journal: Blood
Blood (2013) 122 (21): 2396.
https://doi.org/10.1182/blood.V122.21.2396.2396
Published: 2013
Journal Articles

The Critical Role of Iκbα Dependent Nuclear Export of NF-κb in B-Cell Development.

David T Yang, MD, Shelly Wuerzberger-Davis, PhD, Yuhong Chen, PhD, Mei Yu, Hu Zeng, Paul Bates, PhD, Renren Wen, PhD, Demin Wang, PhD, Shigeki Miyamoto, PhD
Journal: Blood
Blood (2008) 112 (11): 1533.
https://doi.org/10.1182/blood.V112.11.1533.1533
Published: 2008
Journal Articles

Impaired Maturation and Survival of T Lymphocytes, B Lymphocytes, and NK Cells in Mice Lacking Gimap5/Ian5.

Ryan D. Schulteis, Xuezhi Dai, Haiyan Chu, PhD, Brandon Edwards, Dipica Haribhai, Calvin B. Williams, MD, PhD, Subramanium Malarkannan, PhD, Hessner J. Martin, PhD, Kwitek E. Anne, PhD, Åke Lernmark, MD, Jack Gorski, PhD, Demin Wang, PhD, Hartmut Weiler, PhD
Journal: Blood
Blood (2006) 108 (11): 921.
https://doi.org/10.1182/blood.V108.11.921.921
Published: 2006