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Journal Articles

Mathematical Modeling to Identify Clotting Factor Combinations That Modify Thrombin Generation in Hemophilia

Michael Stobb, Dougald Monroe, Keith B. Neeves, Suzanne Sindi, Aaron Fogelson, Karin Leiderman
Journal: Blood
Blood (2022) 140 (Supplement 1): 8432.
https://doi.org/10.1182/blood-2022-169016
Published: 2022
Journal Articles

Emizicumab Promotes Factor Xa Generation on Activated Endothelium in a Blood Cell-Independent Manner

Patrick Ellsworth, Dougald Monroe, Maureane Hoffman, Nigel S Key
Journal: Blood
Blood (2021) 138 (Supplement 1): 3182.
https://doi.org/10.1182/blood-2021-148556
Published: 2021
Journal Articles

In Hemophilia Α Plasma Treated with Emicizumab, Factor IXa in Activated Prothrombin Complex Concentrates Is the Dominant Contributor to Enhanced Thrombin Generation

Dougald Monroe, PhD, Mirella Ezban, PhD, Maureane Hoffman, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-139586
Published: 2020
Journal Articles

In Hemophilia Α Plasma Treated with Emicizumab, Factor IX Activation By Factor VIIa Drives Thrombin Generation

Dougald Monroe, PhD, Mirella Ezban, PhD, Maureane Hoffman, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17.
https://doi.org/10.1182/blood-2020-139712
Published: 2020
Journal Articles

EPCR knockout: inflaming the discussion

Dougald Monroe, Maureane Hoffman
Journal: Blood
Blood (2020) 135 (25): 2201–2202.
https://doi.org/10.1182/blood.2020006001
Published: 2020
Journal Articles

Characterization of a Novel Human Factor VIIa Chimera with Increased Tissue Factor-Independent Activity for Emergency Hemostasis

Ammon Fager, MD PhD, Maureane Hoffman, MD PhD, Dougald Monroe, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3623.
https://doi.org/10.1182/blood-2019-124428
Published: 2019
Journal Articles

Histones Induce the Release of Extracellular Hemoglobin and Red Blood Cell-Derived Microvesicles with Procoagulant Activity

Denis Noubouossie, MD PhD, Juraj Sokol, MD PhD, Mark Gerard Piegore, BS, Anton Ilich, MD, Michael Wayne Henderson, MSc, Micah Mooberry, MD, Dougald Monroe, PhD, Nigel S. Key, MBChB, FRCP
Journal: Blood
Blood (2018) 132 (Supplement 1): 2514.
https://doi.org/10.1182/blood-2018-99-118769
Published: 2018
Journal Articles

Biochemical Characteristics of Emicizumab Activity with Factors IXa, X, and VIIa

Dougald Monroe, PhD, Maureane Hoffman, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1167.
https://doi.org/10.1182/blood-2018-99-116888
Published: 2018
Journal Articles

Prophylactic efficacy of BeneFIX vs Alprolix in hemophilia B mice

Brian Cooley, William Funkhouser, Dougald Monroe, Ashley Ezzell, David M. Mann, Feng-Chang Lin, Paul E. Monahan, Darrel W. Stafford
Journal: Blood
Blood (2016) 128 (2): 286–292.
https://doi.org/10.1182/blood-2016-01-696104
Published: 2016
Journal Articles

At Equal Doses FIXFc (Alprolix) Is Not Significanly Better in a Saphenous Vein Bleeding Model Than Recombinant FIX (BeneFix) Seven Days Post-Infusion

Brian Cooley, PhD, David M Mann, PhD, Dougald Monroe, PhD, Feng-Chang Lin, Paul E. Monahan, MD, Darrel W. Stafford, PhD
Journal: Blood
Blood (2015) 126 (23): 3490.
https://doi.org/10.1182/blood.V126.23.3490.3490
Published: 2015
Journal Articles

Novel Mouse Hemostasis Model for Real-Time Determination of Bleeding Time and Hemostatic Plug Composition

Wolfgang Bergmeier, PhD, Raymond Piatt, Brian G. Petrich, PhD, Dougald Monroe, PhD, Nigel Mackman, PhD, Todd M Getz, PhD
Journal: Blood
Blood (2014) 124 (21): 4177.
https://doi.org/10.1182/blood.V124.21.4177.4177
Published: 2014
Journal Articles

FVIIa as used pharmacologically is not TF dependent in hemophilia B mice

Brief Report
Dengmin Feng, Herbert Whinna, Dougald Monroe, Darrel W. Stafford
Journal: Blood
Blood (2014) 123 (11): 1764–1766.
https://doi.org/10.1182/blood-2013-08-522987
Published: 2014
Journal Articles

Downregulation Of Tissue Factor Expression In Human Pericytes In An Endothelial Cell Co-Culture Model

Stacey A. Snyder, PhD, Maureane Hoffman, MD, PhD, Dougald Monroe, PhD, Samantha L. Lasater
Journal: Blood
Blood (2013) 122 (21): 3524.
https://doi.org/10.1182/blood.V122.21.3524.3524
Published: 2013
Journal Articles

Reversal Of Dabigatran Anticoagulation By a 4-Factor Prothrombin Complex Concentrate: Correlation Between Effects On Parameters Of Thrombin Generation and Hemostatic Effect In Vivo

Maureane Hoffman, MD, PhD, Zoya Volovyk, PhD, Dougald Monroe, PhD
Journal: Blood
Blood (2013) 122 (21): 3643.
https://doi.org/10.1182/blood.V122.21.3643.3643
Published: 2013
Journal Articles

Role of Gamma-Carboxyglutamic Acid (GLA) Domain in Phosphatidylserine (PS)-Regulated Activity of Factor IXa.

Rinku Majumder, PhD, Judson Craft, Alireza Rezaie, Ph.D, R. Barry, Ph.D, Dougald Monroe, Ph.D
Journal: Blood
Blood (2007) 110 (11): 2696.
https://doi.org/10.1182/blood.V110.11.2696.2696
Published: 2007