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Journal Articles

A Model-Informed Precision Busulfan Dosing in Pediatric Patients Undergoing Hematopoietic Cell Transplantation- Real-World Data

Poonkuzhali Balasubramanian, Aswin Anand PAI, Rajesh Nagarajan, Stephanie Hughes, Eunice Sindhuvi Edison, Uday Prakash Kulkarni, Aby Abraham, Alok Srivastava, Vikram Mathews, Biju George

Blood (2022) 140 (Supplement 1): 4743–4744.

https://doi.org/10.1182/blood-2022-166959

Published: 2022

Journal Articles

Combining Arsenic Trioxide and Mitocans Selectively Disrupts Cellular Energetics in Acute Myeloid Leukemia

Nithya Balasundaram, Arvind Venkatraman, Yolanda Augustin, Hamenth Kumar Palani, Swathy Palanikumar, Nair Reeshma Radhakrishnan, Anu Korula, Uday Prakash Kulkarni, Poonkuzhali Balasubramanian, Eunice Sindhuvi, Biju George, Sanjeev Krishna, Vikram Mathews

Blood (2021) 138 (Supplement 1): 2245.

https://doi.org/10.1182/blood-2021-150038

Published: 2021

Journal Articles

Dysregulated Neutrophil Iron Homeostasis in β-Thalassemia Impairs Phagocytosis and Reactive Oxygen Species Production

Sreenithi Santhakumar, Devi V.J, Leo stephen.R, Aruna Barade, Uday Prakash Kulkarni, Biju George, Eunice Sindhuvi

Blood (2021) 138 (Supplement 1): 942.

https://doi.org/10.1182/blood-2021-154482

Published: 2021

Journal Articles

Germline Variants Contribute Significantly to the Pathogenesis of Aplastic Anemia in India

Aruna Barade, Arun Kumar Arunachalam, Deborah Arul, Anu Korula, Anup J Devasia, Fouzia NA, Kavitha M Lakshmi, Aby Abraham, Vikram Mathews, Biju George, Eunice Sindhuvi Edison

Blood (2021) 138 (Supplement 1): 1105.

https://doi.org/10.1182/blood-2021-148348

Published: 2021

Journal Articles

Endothelial Activation and Stress Index (EASIX) Measured Pre-Transplant Identifies a Subgroup with High Transplant Related Mortality in Patients with Thalassemia Undergoing Stem Cell Transplantation Using Thiotepa-Treosulfan-Fludarabine Conditioning

Uday Prakash Kulkarni, Aswin Anand Pai, Kavitha M Lakshmi, Sushil Selvarajan, Sharon Lionel, Anup J Devasia, Anu Korula, Fouzia NA, Eunice Sindhuvi, Aby Abraham, Alok Srivastava, Vikram Mathews, Biju George, Poonkuzhali Balasubramanian

Blood (2021) 138 (Supplement 1): 1781.

https://doi.org/10.1182/blood-2021-152153

Published: 2021

Journal Articles

Treosulfan Metabolite (S, S-EBDM) Pharmacokinetics Influences Regimen Related Toxicity in Patients with Beta Thalassaemia Major Undergoing HSCT

Aswin Anand PAI, MSc, John C Panetta, PhD, Ezhil Pavai Mohanan, PhD, Raveen Stephen Stallon Illangeswaran, MSc, Balaji Balakrishnan, PhD, Eunice Sindhuvi Edison, PhD, Kavitha M Lakshmi, MSc, Uday Prakash Kulkarni, MD DM, Anup Joseph Devasia, MD DM, Fouzia N., Anu Korula, MD DM, Aby Abraham, MD DM, Biju George, MDDM, Vikram Mathews, MD DM, Alok Srivastava, MD,FRACP,FRCPA, Poonkuzhali Balasubramanian, PhD

Blood (2019) 134 (Supplement_1): 1977.

https://doi.org/10.1182/blood-2019-125604

Published: 2019

Journal Articles

Communication of Placental Iron Trafficking Proteins with Maternal and Fetal Iron Regulators

Sreenithi Santhakumar, MTech, Rekha Athiyarath, PhD, Anne George Cherian, MD, Vinod Abraham, MD, Biju George, DM, Eunice Sindhuvi Edison, PhD

Blood (2018) 132 (Supplement 1): 3629.

https://doi.org/10.1182/blood-2018-99-116344

Published: 2018

Journal Articles

Decreased Iron Utilization Leads to Dysregulation of Iron Homeostasis in Aplastic Anemia

Aruna Barade, MTech, Sreenithi Santhakumar, MTech, Biju George, DM, Eunice Sindhuvi Edison, PhD

Blood (2018) 132 (Supplement 1): 3872.

https://doi.org/10.1182/blood-2018-99-118010

Published: 2018

Journal Articles

Targeted IV Vs Oral Busulfan in Very Young Children with Thalassemia Major Undergoing Matched Allogeneic Haematopoietic Stem Cell Transplantation

Poonkuzhali Balasubramanian, MSc, Biju George, DM, Rajesh Nagarajan, B.Sc, Uday Prakash Kulkarni, MD DM, Ezhil Pavai Mohanan, MSc, Eunice Sindhuvi Edison, PhD, Kavitha M Lakshmi, MSc, Yasir Jeelani Samoon, MD DM, Anup Devasia, MD DM, Fouzia N., DNB, DM, Anu Korula, MD DM, Aby Abraham, MD DM, Vikram Mathews, MD, Alok Srivastava, MD FRACP, FRCPA

Blood (2018) 132 (Supplement 1): 5707.

https://doi.org/10.1182/blood-2018-99-114547

Published: 2018

Journal Articles

Higher Incidence of Graft Rejection in Non-Sibling Fully Matched Related Donor Stem Cell Transplants for Thalassemia Major: A Cautionary Note

Anu Korula, MD DM, Fouzia N., DNB, DM, Anup Devasia, MD DM, Uday Prakash Kulkarni, MD DM, Kavitha M Lakshmi, MSc, Eunice Sindhuvi Edison, PhD, Aby Abraham, MD DM, Alok Srivastava, MD FRACP, FRCPA, Biju George, DM, Vikram Mathews, MD

Blood (2018) 132 (Supplement 1): 2178.

https://doi.org/10.1182/blood-2018-99-114454

Published: 2018

Journal Articles

Donor Telomere Length Influences Engraftment and Outcome in Aplastic Anemia Patients Undergoing Matched Related Stem Cell Transplantation

Aruna Barade, M.Tech, Anu Korula, MD DM, Nisham PN, MD DM, Kavitha M Lakshmi, MSc, Uday Prakash Kulkarni, MD DM, Anup Devasia, MDDM, Aby Abraham, MD DM, Alok Srivastava, MD, Vikram Mathews, MD DM, Eunice Sindhuvi Edison, PhD, Biju George, MDDM

Blood (2017) 130 (Supplement 1): 1184.

https://doi.org/10.1182/blood.V130.Suppl_1.1184.1184

Published: 2017

Journal Articles

Telomere Length Is Significantly Reduced in Patients with Aplastic Anemia and Is Not Influenced By Gender and Severity

Eunice Sindhuvi Edison, PhD, Aruna Barade, M.Tech, Anu Korula, MD DM, Nisham PN, MD DM, Anup Joseph Devasia, MD DM, Kavitha M Lakshmi, MSc, Kulkarni Uday Prakash, Aby Abraham, MD DM, Alok Srivastava, MD, Vikram Mathews, MD DM, Biju George, MDDM

Blood (2017) 130 (Supplement 1): 4964.

https://doi.org/10.1182/blood.V130.Suppl_1.4964.4964

Published: 2017

Journal Articles

Alteration of the Hematopoietic Components, Mesenchymal Stromal Cells and Vascular Elements in the Bone Marrow Niche in Myelodysplastic Syndrome: Refractory Cytopenia with Multilineage Dysplasia

Salar Abbas, M.Sc, Aparna Venkatraman, PhD, Sanjay Kumar, PhD, Archana Kini, M.Sc, Marie Therese Manipadam, MD, Vivi M Srivastava, MD, Eunice Sindhuvi, PhD, Vikram Mathews, MD DM, Biju George, MD DM, Alok Srivastava

Blood (2016) 128 (22): 5516.

https://doi.org/10.1182/blood.V128.22.5516.5516

Published: 2016

Journal Articles

Molecular Basis of Von Willebrand Disease in Patients from India

Sumitha Elayaperumal, M.Sc, Eunice Sindhuvi Edison, PhD, Sankari Devi Govindanattar, B.Sc, Surendar Singh, B.Sc, Aby Abraham, MD DM, Biju George, DM, Auro Viswabandya, MD DM, Sukesh Nair, MD FRCPA, Alok Srivastava, MD FRACP

Blood (2015) 126 (23): 1102.

https://doi.org/10.1182/blood.V126.23.1102.1102

Published: 2015

Journal Articles

Population Pharmacokinetics of Fludarabine and Treosulfan in Patients with Thalassemia Undergoing Hematopoietic Stem Cell Transplantation

Ezhil Pavai Mohanan, MSc, John C Panetta, PhD, Shareen Stella Backia Royan, BSc, Ajay Abraham, MSc, Eunice Sindhuvi Edison, PhD, Kavitha M Lakshmi, MSc, Fouzia Nambiathayil Abubacker, DM, Anu Korula, MD DM, Aby Abraham, MD DM, Auro Viswabandya, MD DM, Biju George, DM, Alok Srivastava, MD FRACP, Vikram Mathews, DM, Poonkuzhali Balasubramanian, PhD

Blood (2015) 126 (23): 3120.

https://doi.org/10.1182/blood.V126.23.3120.3120

Published: 2015

Journal Articles

Donor Lymphocyte Infusion in Patients with Thalassemia Major Who Have Mixed Chimerism Following Allogeneic Stem Cell Transplant

Aby Abraham, MD DM, Eunice Sindhuvi, PhD, Anu Korula, MD DM, Fouzia NA, Dip NB, DM,, Alok Srivastava, MD FRACP, Biju George, DM, Vikram Mathews, DM

Blood (2015) 126 (23): 1965.

https://doi.org/10.1182/blood.V126.23.1965.1965

Published: 2015

Journal Articles

Molecular Basis Of (δβ) 0 Thalassaemia and HPFH In Indian Population and The Role Of Non-Coding Transcripts In Increased Foetal Hemoglobin In Adults

Thiyagaraj Mayuranathan, MSc, Janakiram Rayabaram, MSc, Reena Das, MD, Neeraj Arora, MD, Eunice Sindhuvi Edison, Ph.D, Alok Srivastava, MD, Shaji Velayudhan, PhD

Blood (2013) 122 (21): 3446.

https://doi.org/10.1182/blood.V122.21.3446.3446

Published: 2013

Journal Articles

Role Of Stress Responsive Genes Responsible In Molecular Switch From Adaptive Phase To Apoptosis In HbE−β Thalassemia

Divya Jayasree, MSc, Ramachandran V Shaji, Biju George, MD, Alok Srivastava, MD, Vikram Mathews, MD, Eunice Sindhuvi Edison, Ph.D

Blood (2013) 122 (21): 3447.

https://doi.org/10.1182/blood.V122.21.3447.3447

Published: 2013

Journal Articles

A Robust Ex-Vivo Erythropoiesis System For Studying Transcriptional Regulation Of Globin Genes In Thalassaemia

Janakiram Rayabaram, MSc, Thiyagaraj Mayuranathan, MSc, Divya Jayasree, MSc, Neeraj Arora, MD, Eunice Sindhuvi Edison, Ph.D, Alok Srivastava, MD, Shaji Velayudhan, PhD

Blood (2013) 122 (21): 2259.

https://doi.org/10.1182/blood.V122.21.2259.2259

Published: 2013

Journal Articles

Molecular and Functional Characterization of Two Novel Missense Mutations in Iron Transport Protein Causing Hypochromic Microcytic Anemia and Hemosiderosis

Rekha Athiyarath, Neeraj Arora, MD, Rayaz Ahmed, MD, Biju George, MD, Mammen Chandy, MD, Alok Srivastava, MD, Eunice Sindhuvi Edison, Ph.D

Blood (2012) 120 (21): 3202.

https://doi.org/10.1182/blood.V120.21.3202.3202

Published: 2012

NARROW

A Model-Informed Precision Busulfan Dosing in Pediatric Patients Undergoing Hematopoietic Cell Transplantation- Real-World Data

Combining Arsenic Trioxide and Mitocans Selectively Disrupts Cellular Energetics in Acute Myeloid Leukemia

Dysregulated Neutrophil Iron Homeostasis in β-Thalassemia Impairs Phagocytosis and Reactive Oxygen Species Production

Germline Variants Contribute Significantly to the Pathogenesis of Aplastic Anemia in India

Endothelial Activation and Stress Index (EASIX) Measured Pre-Transplant Identifies a Subgroup with High Transplant Related Mortality in Patients with Thalassemia Undergoing Stem Cell Transplantation Using Thiotepa-Treosulfan-Fludarabine Conditioning

Treosulfan Metabolite (S, S-EBDM) Pharmacokinetics Influences Regimen Related Toxicity in Patients with Beta Thalassaemia Major Undergoing HSCT

Communication of Placental Iron Trafficking Proteins with Maternal and Fetal Iron Regulators

Decreased Iron Utilization Leads to Dysregulation of Iron Homeostasis in Aplastic Anemia

Targeted IV Vs Oral Busulfan in Very Young Children with Thalassemia Major Undergoing Matched Allogeneic Haematopoietic Stem Cell Transplantation

Higher Incidence of Graft Rejection in Non-Sibling Fully Matched Related Donor Stem Cell Transplants for Thalassemia Major: A Cautionary Note

Donor Telomere Length Influences Engraftment and Outcome in Aplastic Anemia Patients Undergoing Matched Related Stem Cell Transplantation

Telomere Length Is Significantly Reduced in Patients with Aplastic Anemia and Is Not Influenced By Gender and Severity

Alteration of the Hematopoietic Components, Mesenchymal Stromal Cells and Vascular Elements in the Bone Marrow Niche in Myelodysplastic Syndrome: Refractory Cytopenia with Multilineage Dysplasia

Molecular Basis of Von Willebrand Disease in Patients from India

Population Pharmacokinetics of Fludarabine and Treosulfan in Patients with Thalassemia Undergoing Hematopoietic Stem Cell Transplantation

Donor Lymphocyte Infusion in Patients with Thalassemia Major Who Have Mixed Chimerism Following Allogeneic Stem Cell Transplant

Molecular Basis Of (δβ) 0 Thalassaemia and HPFH In Indian Population and The Role Of Non-Coding Transcripts In Increased Foetal Hemoglobin In Adults

Role Of Stress Responsive Genes Responsible In Molecular Switch From Adaptive Phase To Apoptosis In HbE−β Thalassemia

A Robust Ex-Vivo Erythropoiesis System For Studying Transcriptional Regulation Of Globin Genes In Thalassaemia

Molecular and Functional Characterization of Two Novel Missense Mutations in Iron Transport Protein Causing Hypochromic Microcytic Anemia and Hemosiderosis

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American Society of Hematology

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