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Frédéric ADAM
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Journal Articles

Fitusiran reduces bleeding in factor X–deficient mice

Sebastien Verhenne, Geneviève McCluskey, Hortense Maynadié, Frédéric Adam, Caterina Casari, Laurence Panicot-Dubois, Lydie Crescence, Christophe Dubois, Cécile V. Denis, Peter J. Lenting, Olivier D. Christophe
Journal: Blood
Blood (2024) 144 (2): 227–236.
https://doi.org/10.1182/blood.2023023404
Published: 2024
Includes: Multimedia, Supplemental data
Journal Articles

Efficacy of platelet-inspired hemostatic nanoparticles on bleeding in von Willebrand disease murine models

Stéphanie Roullet, Norman Luc, Julie Rayes, Jean Solarz, Dante Disharoon, Andrew Ditto, Emily Gahagan, Christa Pawlowski, Thibaud Sefiane, Frédéric Adam, Caterina Casari, Olivier D. Christophe, Michael Bruckman, Peter J. Lenting, Anirban Sen Gupta, Cécile V. Denis
Journal: Blood
Blood (2023) 141 (23): 2891–2900.
https://doi.org/10.1182/blood.2022018956
Published: 2023
Includes: Multimedia, Supplemental data
Journal Articles

DOCK11 deficiency in patients with X-linked actinopathy and autoimmunity

Charlotte Boussard, Laure Delage, Tania Gajardo, Alexandre Kauskot, Maxime Batignes, Nicolas Goudin, Marie-Claude Stolzenberg, Camille Brunaud, Patricia Panikulam, Quentin Riller, Maryse Moya-Nilges, Jean Solarz, Christelle Repérant, Béatrice Durel, Jean-Claude Bordet, Olivier Pellé, Corinne Lebreton, Aude Magérus, Vithura Pirabakaran, Pablo Vargas, Sébastien Dupichaud, Marie Jeanpierre, Angélique Vinit, Mohammed Zarhrate, Cécile Masson, Nathalie Aladjidi, Peter D. Arkwright, Brigitte Bader-Meunier, Sandrine Baron Joly, Joy Benadiba, Elise Bernard, Dominique Berrebi, Christine Bodemer, Martin Castelle, Fabienne Charbit-Henrion, Marwa Chbihi, Agathe Debray, Philippe Drabent, Sylvie Fraitag, Miguel Hié, Judith Landman-Parker, Ludovic Lhermitte, Despina Moshous, Pierre Rohrlich, Frank Ruemmele, Anne Welfringer-Morin, Maud Tusseau, Alexandre Belot, Nadine Cerf-Bensussan, Marie Roelens, Capucine Picard, Bénédicte Neven, Alain Fischer, Isabelle Callebaut, Mickaël Ménager, Fernando E. Sepulveda, Frédéric Adam, Frédéric Rieux-Laucat
Journal: Blood
Blood (2023) 141 (22): 2713–2726.
https://doi.org/10.1182/blood.2022018486
Published: 2023
Includes: Supplemental data
Journal Articles

Long-Term Follow-up Study after Lentiviral Hematopoietic Stem/Progenitor Cell Gene Therapy for Wiskott - Aldrich Syndrome

Alessandra Magnani, Michaela Semeraro, Frédéric ADAM, Claire Booth, Loic Dupre, Emma C Morris, Aurélie Gabrion, Cecile Roudaut, Delphine Borgel, Antoine Toubert, Emmanuel Clave, Chrystelle Abdo, Guy Gorochov, Rachel Petermann, Mélanie Guiot, Makoto Miyara, Despina Moshous, Elisa Magrin, Adeline Denis, Felipe Suarez, Chantal Lagresle-Peyrou, Aoife Doto, John K. Everett, Amélie Trinquand, Marianne Guisset, Jin Hua Xu-Bayford, Salima Hacein-Bey-Abina, Alexandre Kauskot, Reem Elfeky, Christine Rivat, Sarah Abbas, Bobby H Gaspar, Elizabeth A. Macintyre, Capucine Picard, Frederic D. Bushman, Anne Galy, Alain Fischer, Emmanuelle Six, Adrian J. Thrasher, Marina Cavazzana
Journal: Blood
Blood (2021) 138 (Supplement 1): 2934.
https://doi.org/10.1182/blood-2021-147697
Published: 2021
Journal Articles

A mutation of the human EPHB2 gene leads to a major platelet functional defect

Eliane Berrou, Christelle Soukaseum, Rémi Favier, Frédéric Adam, Ziane Elaib, Alexandre Kauskot, Jean-Claude Bordet, Paola Ballerini, Stephane Loyau, Miao Feng, Karine Dias, Abbas Muheidli, Stephane Girault, Alan T. Nurden, Ernest Turro, Willem H. Ouwehand, Cécile V. Denis, Martine Jandrot-Perrus, Jean-Philippe Rosa, Paquita Nurden, Marijke Bryckaert
Journal: Blood
Blood (2018) 132 (19): 2067–2077.
https://doi.org/10.1182/blood-2018-04-845644
Published: 2018
Includes: Supplemental data
Journal Articles

Full activation of mouse platelets requires ADP secretion regulated by SERCA3 ATPase–dependent calcium stores

Ziane Elaïb, Frédéric Adam, Eliane Berrou, Jean-Claude Bordet, Nicolas Prévost, Régis Bobe, Marijke Bryckaert, Jean-Philippe Rosa
Journal: Blood
Blood (2016) 128 (8): 1129–1138.
https://doi.org/10.1182/blood-2015-10-678383
Published: 2016
Includes: Supplemental data
Journal Articles

Apelin: an antithrombotic factor that inhibits platelet function

Frédéric Adam, Abdel-Majid Khatib, Jose Javier Lopez, Camille Vatier, Sabrina Turpin, Adeline Muscat, Fabienne Soulet, Anne Aries, Isaac Jardin, Régis Bobe, Alain Stepanian, Dominique de Prost, Cédric Dray, Juan Antonio Rosado, Philippe Valet, Bruno Feve, Geraldine Siegfried
Journal: Blood
Blood (2016) 127 (7): 908–920.
https://doi.org/10.1182/blood-2014-05-578781
Published: 2016
Includes: Supplemental data
Journal Articles

Mechanisms and Therapeutic Modulation of the Bleeding Tendency in Genetically-Engineered Von Willebrand Disease Type 2B Mice

Fatoumata Tall, MD, Frederic Adam, PhD, Amine Bazaa, PhD, Olivier D. Christophe, PhD, Peter J. Lenting, PhD, Cecile V. Denis, PhD, Valerie Proulle, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3516.
https://doi.org/10.1182/blood.V126.23.3516.3516
Published: 2015
Journal Articles

Thrombocytopenia resulting from mutations in filamin A can be expressed as an isolated syndrome

Clinical Trials & Observations
Paquita Nurden, Najet Debili, Isabelle Coupry, Marijke Bryckaert, Ibtissam Youlyouz-Marfak, Guilhem Solé, Anne-Cécile Pons, Eliane Berrou, Frédéric Adam, Alexandre Kauskot, Jean-Marie Daniel Lamazière, Philippe Rameau, Patricia Fergelot, Caroline Rooryck, Dorothée Cailley, Benoît Arveiler, Didier Lacombe, William Vainchenker, Alan Nurden, Cyril Goizet
Journal: Blood
Blood (2011) 118 (22): 5928–5937.
https://doi.org/10.1182/blood-2011-07-365601
Published: 2011
Includes: Supplemental data
Journal Articles

Platelet JNK1 is involved in secretion and thrombus formation

Frédéric Adam, Alexandre Kauskot, Paquita Nurden, Eric Sulpice, Marc F. Hoylaerts, Roger J. Davis, Jean-Philippe Rosa, Marijke Bryckaert
Journal: Blood
Blood (2010) 115 (20): 4083–4092.
https://doi.org/10.1182/blood-2009-07-233932
Published: 2010
Journal Articles

Anticoagulant and antithrombotic properties of platelet protease nexin-1

Yacine Boulaftali, Frédéric Adam, Laurence Venisse, Véronique Ollivier, Benjamin Richard, Sabrina Taieb, Denis Monard, Rémi Favier, Marie-Christine Alessi, Marijke Bryckaert, Véronique Arocas, Martine Jandrot-Perrus, Marie-Christine Bouton
Journal: Blood
Blood (2010) 115 (1): 97–106.
https://doi.org/10.1182/blood-2009-04-217240
Published: 2010
Includes: Supplemental data
Journal Articles

Insights into Disturbed Hemostasis in the Quebec Platelet Disorder Using Thromboelastography, Blood Clots Formed at Low Shear, and Perfusion Studies of Fibrinolysis.

Maria Diamandis, Hon., BSc, Frederic Adam, PhD, Georges E. Rivard, MD, Walter H.A. Kahr, MD, PhD, Catherine P.M. Hayward, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2135.
https://doi.org/10.1182/blood.V106.11.2135.2135
Published: 2005
Journal Articles

Mechanisms of Static and Shear-Induced Platelet Adhesion: Differences in the Adhesion Supported by MMRN1 Comparisons with Other β3 Integrin Ligands.

Frederic Adam, PhD, Shilun Zheng, DVM MSc, Aurelio V. Santos, BSMT, John G. Kelton, MD, Catherine P.M. Hayward, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2659.
https://doi.org/10.1182/blood.V106.11.2659.2659
Published: 2005
Journal Articles

The Proadhesive Properties of Multimerin in Supporting Cellular Adhesion: Evidence for RGD and Non-RGD Dependent Adhesive Mechanisms.

Frederic Adam, PhD, Shilun Zheng, DVM MSc, Nilesh Joshi, Youko Suehiro, MD PhD, David S. Kelton, Amin Sandhu, Samira Jeimy, Catherine P.M. Hayward, MD PhD
Journal: Blood
Blood (2004) 104 (11): 3917.
https://doi.org/10.1182/blood.V104.11.3917.3917
Published: 2004
Journal Articles

Human Platelets Contain Forms of Factor V in Disulfide-Linkage with Multimerin.

Catherine P.M. Hayward, MD PhD, Nola Fuller, MSc, Shilun Zheng, DVM MSc, Frederic Adam, PhD, Samira Jeimy, Ian Horsewood, Mary Ann Quinn-Allen, William H. Kane, MD PhD
Journal: Blood
Blood (2004) 104 (11): 1933.
https://doi.org/10.1182/blood.V104.11.1933.1933
Published: 2004