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Journal Articles

Vcp-Regulated Homologous Recombination Represents a New Druggable Vulnerability in Acute Myeloid Leukemia

Lina Benajiba, Nina Fenouille, Edyta Malolepsza, Jana M Ellegast, MD, Gabriela Alexe, Yana Pikman, MD, Frédéric Luciano, Ilene Galinsky, Daniel J. DeAngelo, MD, Richard M. Stone, MD, Patrick Auberger, PhD, Josee Guirouilh-Barbat, Bernard Lopez, Mehdi Khaled, Kasper Lage, Olivier Hermine, MD PhD, Michael Hemann, Alexandre Puissant, Kimberly Stegmaier, MD

Blood (2017) 130 (Supplement 1): 880.

https://doi.org/10.1182/blood.V130.Suppl_1.880.880

Published: 2017

Journal Articles

Targeting the Creatine Kinase Pathway in EVI1-Positive Acute Myeloid Leukemia

Alexandre Puissant, PhD, Nina Fenouille, PhD, Christopher F. Bassil, BA, Issam Ben-Sahra, PhD, Lina Benajiba, Gabriela Alexe, PhD, Azucena Ramos, Yana Pikman, MD, Michael R. Burgess, MD PhD, Qing Li, MD PhD, Frederic Luciano, PhD, Patrick Auberger, PhD, Ilene Galinsky, MSN, ANPc, Daniel J. DeAngelo, MD PhD, Richard M. Stone, MD, Archibald S. Perkins, MD PhD, Kevin Shannon, MD, Michael T. Hemann, PhD, Kimberly Stegmaier, MD

Blood (2016) 128 (22): 523.

https://doi.org/10.1182/blood.V128.22.523.523

Published: 2016

Journal Articles

Implication of the Anti-Apoptotic Protein Bcl-B (BCL2L10) in the Pathogenesis of Multiple Myeloma

Valentine Richez, Jr., MD, Frederic Luciano, PhD, Amine Hamouda, PhD, Alexandre Puissant, Guillaume Robert, PhD, Arnaud Jacquel, PhD, Thomas Cluzeau, MDPhD, Kenneth C Anderson, MD, Jean-Gabriel Fuzibet, MD, Patrick Auberger, PhD

Blood (2015) 126 (23): 2958.

https://doi.org/10.1182/blood.V126.23.2958.2958

Published: 2015

Journal Articles

BCL2L10 Quantification Is a Predictive Factor of Response to Azacitidine in Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Valerie Vidal, Clemence Ginet, Jean Michel Karsenti, MD, Frederic Luciano, PhD, Lauris Gastaud, MD, Georges Garnier, MD, Thorsten Braun, MD, Pierre Hirsch, MD, Emmanuel Raffoux, MD, Anne Marie Nloga, Herve Dombret, MD, Pierre-Simon Rohrlich, Lionel Ades, MD PhD, Christine Chomienne, MD PhD, Pierre Fenaux, MD PhD, Patrick Auberger, PhD, Guillaume Robert, PhD, Thomas Cluzeau, MD PhD

Blood (2014) 124 (21): 3261.

https://doi.org/10.1182/blood.V124.21.3261.3261

Published: 2014

Journal Articles

The P2Y6-AMPK Pathway Triggers Autophagy during CSF-1-Induced Human Monocyte Differentiation and Is a Potential Target in CMML

Sandrine Obba, PhDstudent, Zoheir Hizir, PhDstudent, Dorothée Selimoglu-Buet, PhD, Laurent Boyer, PhD, Anja Pfeifer, PhD, Mohamed-Amine Hamouda, PhDstudent, Diogo Goncalves, Michael Cerezo, PhDstudent, Sandrine Marchetti, PhD, Stephane Rocchi, PhD, Nathalie Droin, PhD, Guillaume Robert, PhD, Frederic Luciano, PhD, Bernard Robaye, PhD, Benoit Viollet, PhD, Laurence Legros, MD PhD, Eric Solary, MD PhD, Patrick Auberger, PhD, Arnaud Jacquel, PhD

Blood (2014) 124 (21): 4347.

https://doi.org/10.1182/blood.V124.21.4347.4347

Published: 2014

Journal Articles

Evaluation Of Acadesine, a Drug Stimulating Cell Autophagy, In Azacitidine(AZA)-Resistant Myelodysplastic Syndromes (MDS)

Thomas Cluzeau, MD, PhD, Guillaume Robert, PhD, Jean Michel Karsenti, MD, Frederic Luciano, PhD, Nicolas Mounier, MD, PhD, Jill Patrice Cassuto, MD, PhD, Lionel Ades, Sophie Raynaud, MD, PhD, Pierre Fenaux, MD, PhD, Patrick Auberger, PhD

Blood (2013) 122 (21): 1568.

https://doi.org/10.1182/blood.V122.21.1568.1568

Published: 2013

Journal Articles

BCL2L10 (Bcl-B) Is Associated with Resistance to Azacitidine (AZA) in MDS and AML, and Is a Possible Therapeutic Target in AZA Resistant Patients

Thomas Cluzeau, MD, PhD, Guillaume Robert, Jean-Michel Karsenti, MD, Frederic Luciano, Alexandre Puissant, Faezeh Legrand, MD, PhD, Lionel Mannone, MD, Aline Renneville, MD, Claude Preudhomme, Pierre Fenaux, MD, PhD, Jill-Patrice Cassuto, MD, Sophie Raynaud, Nicolas Mounier, MD, PhD, Patrick Auberger, MD, PhD

Blood (2012) 120 (21): 701.

https://doi.org/10.1182/blood.V120.21.701.701

Published: 2012

Journal Articles

Autophagy is required for CSF-1–induced macrophagic differentiation and acquisition of phagocytic functions

Arnaud Jacquel, Sandrine Obba, Laurent Boyer, Maeva Dufies, Guillaume Robert, Pierre Gounon, Emmanuel Lemichez, Frederic Luciano, Eric Solary, Patrick Auberger

Blood (2012) 119 (19): 4527–4531.

https://doi.org/10.1182/blood-2011-11-392167

Published: 2012

Includes: Supplemental data

Journal Articles

Induction of Autophagic Cell Death Circumvents Azacitidine-Resistance In Myelodysplastic Syndrome-Derived Cell Lines

Thomas Cluzeau, Guillaume Robert, Jean-Michel Karsenti, Frederic Luciano, Alexandre Puissant, S. Dominique Raynaud, MD, Lionel Mannone, Jill-Patrice Cassuto, Nicolas Mounier, Patrick Auberger

Blood (2010) 116 (21): 1817.

https://doi.org/10.1182/blood.V116.21.1817.1817

Published: 2010

Journal Articles

Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma

Frederic Luciano, Maryla Krajewska, Paulina Ortiz-Rubio, Stan Krajewski, Dayong Zhai, Benjamin Faustin, Jean-Marie Bruey, Beatrice Bailly-Maitre, Alan Lichtenstein, Siva Kumar Kolluri, Arnold C. Satterthwait, Xiao-Kun Zhang, John C. Reed

Blood (2007) 109 (9): 3849–3855.

https://doi.org/10.1182/blood-2006-11-056879

Published: 2007

Includes: Supplemental data

Journal Articles

Exploiting the Tr3 Interaction with Bcl-2 as a Novel Therapeutic Strategy of Cancer and Leukemia Therapy.

Dayong Zhai, PhD, Eduard Sergienko, Ph.D., Shinichi Kitada, M.D., Ph.D., Frederic Luciano, Ph.D., Arnold C. Satterswait, Ph.D., Xiaokun Zhang, B.S., John C. Reed, M.D., Ph.D.

Blood (2006) 108 (11): 256.

https://doi.org/10.1182/blood.V108.11.256.256

Published: 2006

Journal Articles

In Vitro Reconstitution of the NALP1 Inflammasome Reveals Requirements for Caspase Activation.

Benjamin Faustin, PhD, Lydia Lartigue, Ph.D., Jean-Marie Bruey, Ph.D., Frederic Luciano, Ph.D., Dorit Hanein, Ph.D., Isabelle Rouiller, Ph.D., John C. Reed, MD, Ph.D.

Blood (2006) 108 (11): 3658.

https://doi.org/10.1182/blood.V108.11.3658.3658

Published: 2006

Journal Articles

Caspase-Activating Protein Nalp1 Is Directly Suppressed by Bcl-2 and Bcl-Xl.

Jean Marie Bruey, PhD, Nathalie Bruey-Sedano, Ph.D., Frederic Luciano, Ph.D., Dayong Zhai, Ph.D., Andrei Osterman, Ph.D., Shu-ichi Matsuzawa, Ph.D., Alexey Terskikh, Ph.D., Benjamin Faustin, Ph.D., John C. Reed, MD,Ph.D

Blood (2006) 108 (11): 1430.

https://doi.org/10.1182/blood.V108.11.1430.1430

Published: 2006

Journal Articles

Orphan Nuclear Receptor TR3 (Nur77) Binds and Converts the Phenotype of Bcl-B, an Anti-Apoptotic Bcl-2-Family Protein Predominantly Expressed in Human Plasma Cells.

Frederic Luciano, PhD, Maryla Krajewska, M.D., Xiaokun Zhang, Ph.D., Arnold Satterthwait, Ph.D., John C. Reed, MD, Ph.D.

Blood (2006) 108 (11): 82.

https://doi.org/10.1182/blood.V108.11.82.82

Published: 2006

Journal Articles

Tcl-1 Inhibits Nuclear Export of TR3 and Is Highly Expressed in ZAP70-Positive CLL B-Cells.

Irene M. Pedersen, Ph.D., Frederic Luciano, Ph.D., Xiao-kun Zhang, Ph.D., Carlo M. Croce, Ph.D., Thomas J. Kipps, M.D., Ph.D., Dennis A. Carson, M.D., Ph.D., John C. Reed, M.D., Ph.D.

Blood (2004) 104 (11): 967.

https://doi.org/10.1182/blood.V104.11.967.967

Published: 2004

NARROW

Vcp-Regulated Homologous Recombination Represents a New Druggable Vulnerability in Acute Myeloid Leukemia

Targeting the Creatine Kinase Pathway in EVI1-Positive Acute Myeloid Leukemia

Implication of the Anti-Apoptotic Protein Bcl-B (BCL2L10) in the Pathogenesis of Multiple Myeloma

BCL2L10 Quantification Is a Predictive Factor of Response to Azacitidine in Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

The P2Y6-AMPK Pathway Triggers Autophagy during CSF-1-Induced Human Monocyte Differentiation and Is a Potential Target in CMML

Evaluation Of Acadesine, a Drug Stimulating Cell Autophagy, In Azacitidine(AZA)-Resistant Myelodysplastic Syndromes (MDS)

BCL2L10 (Bcl-B) Is Associated with Resistance to Azacitidine (AZA) in MDS and AML, and Is a Possible Therapeutic Target in AZA Resistant Patients

Autophagy is required for CSF-1–induced macrophagic differentiation and acquisition of phagocytic functions

Induction of Autophagic Cell Death Circumvents Azacitidine-Resistance In Myelodysplastic Syndrome-Derived Cell Lines

Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma

Exploiting the Tr3 Interaction with Bcl-2 as a Novel Therapeutic Strategy of Cancer and Leukemia Therapy.

In Vitro Reconstitution of the NALP1 Inflammasome Reveals Requirements for Caspase Activation.

Caspase-Activating Protein Nalp1 Is Directly Suppressed by Bcl-2 and Bcl-Xl.

Orphan Nuclear Receptor TR3 (Nur77) Binds and Converts the Phenotype of Bcl-B, an Anti-Apoptotic Bcl-2-Family Protein Predominantly Expressed in Human Plasma Cells.

Tcl-1 Inhibits Nuclear Export of TR3 and Is Highly Expressed in ZAP70-Positive CLL B-Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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