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Francesca Vinchi, PhD
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Journal Articles

Iron Handling by Macrophages

Francesca Vinchi, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): SCI6.
https://doi.org/10.1182/blood-2020-133057
Published: 2020
Journal Articles

Intravenous Iron Promotes Low-Grade Inflammation in Anemic Patients By Triggering Macrophage Activation

Francesca Vinchi, PhD, Annalisa Castagna, B.S., PhD, Milene Costa da Silva, Fabiana Busti, MD PhD, Giacomo Marchi, MD, Richard Sparla, Martina U. Muckenthaler, PhD, Domenico Girelli, MD, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 957.
https://doi.org/10.1182/blood-2019-132235
Published: 2019
Journal Articles

Transfusion-Induced Impairment of Macrophage Responses Is Partially Restored By the Iron Chelator Deferasirox

Francesca Vinchi, PhD, Richard Sparla, Sara Passos, PhD, Heike Weidner, Martina Rauner, PhD, Uwe Platzbecker, Martina U. Muckenthaler, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3625.
https://doi.org/10.1182/blood-2018-99-113016
Published: 2018
Journal Articles

Systemic Heme and Iron Overload Results in Depletion of Serum Hemopexin, Haptoglobin and Transferrin and Correlates with Markers of Endothelial Activation and Lipid Oxidation in Beta Thalassemia Major and Intermedia

Francesca Vinchi, PhD, Gregory M Vercellotti, MD, John D. Belcher, PhD, Eitan Fibach, PhD, Hala Zreid, MD, Rushdy Rasras, Hussam Ghoti, MD, Martina U. Muckenthaler, PhD, Eliezer A. Rachmilewitz, MD
Journal: Blood
Blood (2016) 128 (22): 2469.
https://doi.org/10.1182/blood.V128.22.2469.2469
Published: 2016
Journal Articles

Low-Iron Diet and Chelation Therapy Rescue Severe Atherosclerosis Associated with High Circulating Iron Levels

Francesca Vinchi, PhD, Andreas Simmelbauer, Master student, Sandro Altamura, PhD, Sebastian Spaich, Richard Sparla, Bruno Galy, PhD, Matthias W. Hentze, MD, Martina U. Muckenthaler, PhD
Journal: Blood
Blood (2016) 128 (22): 199.
https://doi.org/10.1182/blood.V128.22.199.199
Published: 2016
Journal Articles

High Circulating Iron Levels Are a Risk Factor for Cardiovascular Disease: Clinical Implications for Iron-Overload Conditions

Francesca Vinchi, PhD, Andreas Simmelbauer, Master student, Milene Costa da Silva, PhDstudent, Sandro Altamura, PhD, Bruno Galy, PhD, Matthias W. Hentze, MD, Martina U. Muckenthaler, PhD
Journal: Blood
Blood (2015) 126 (23): 1040.
https://doi.org/10.1182/blood.V126.23.1040.1040
Published: 2015
Journal Articles

The Heme Scavenger Hemopexin Reverts Heme-Driven Pro-Inflammatory Phenotypic Switching of Macrophages in Sickle Cell Disease

Francesca Vinchi, PhD, Milene Costa da Silva, PhDstudent, Giada Ingoglia, PhDstudent, Sara Petrillo, PhDstudent, Nathan Brinkman, Adrian Zuercher, Adelheid Cerwenka, PhD, Emanuela Tolosano, PhD, Martina U. Muckenthaler, PhD
Journal: Blood
Blood (2015) 126 (23): 2205.
https://doi.org/10.1182/blood.V126.23.2205.2205
Published: 2015