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Journal Articles

Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma

Nitin Agarwal, PhD, Kranthi Kunkalla, Daniel Bilbao, PhD, Ralf Landgraf, PhD, Francisco Vega, MD PhD

Blood (2019) 134 (Supplement_1): 3972.

https://doi.org/10.1182/blood-2019-121847

Published: 2019

Journal Articles

NPM-ALK Upregulates Jab1/Csn5 through STAT3 Activation in Anaplastic Large Cell Lymphoma: A Novel Function of NPM-ALK That Contributes to PD1/PD-L1 Immune Checkpoint Regulation

Elias Drakos, MD PhD Prof., Konstantina Stathopoulou, MSc., Lingxiao Li, PhD, Daniel Bilbao, Vasiliki Leventaki, Pedro Farrajota Neves Da Silva, MD, Vasileios Atsaves, PhD, Anders Österborg, MD PhD, L. Jeffrey Medeiros, MD, Francisco Vega, MD PhD, Jonathan H. Schatz, MD, Francois Claret, PhD, George Z. Rassidakis, MD PhD Prof.

Blood (2019) 134 (Supplement_1): 2796.

https://doi.org/10.1182/blood-2019-130457

Published: 2019

Journal Articles

CRISPR/Cas9 Generation of Npm1-Alk in Transplantable Murine Hematopoietic Stem Cells Accurately Models ALK-Positive Lymphoma in Recipients

Soumya Sundara Rajan, MSc, Lingxiao Li, PhD, Kranthi Kunkalla, Amit Dipak Amin, PhD, Nitin Agarwal, Francisco Vega, MD PhD, Jonathan H. Schatz, MD

Blood (2018) 132 (Supplement 1): 779.

https://doi.org/10.1182/blood-2018-99-114692

Published: 2018

Journal Articles

Genetic Landscape of Ocular Adnexa Extranodal Marginal Zone Lymphoma

Marco Magistri, PhD MS, Lanie Happ, Jeremy Ramdial, MD, Kranthi Kunkalla, Sander R Dubovy, MD, Jennifer R Chapman, MD, Francisco Vega, MD PhD, Sandeep Dave, MD, Izidore S. Lossos, MD

Blood (2018) 132 (Supplement 1): 923.

https://doi.org/10.1182/blood-2018-99-111325

Published: 2018

Journal Articles

LMO2 Facilitates Synthetic Lethality after PARP Inhibition (PARPi) in Diffuse Large B-Cell Lymphoma (DLBCL)

Ramiro E Verdun, PhD, Salma Parvin, PhD, Ariel Ramirez Labrada, PhD, Gabriel Emmanuel Santiago, Cortizas M Elena, Sharabi Eden, Aumann Shlomzion, MD, Zhang Yu, PhD, Isidro Sanchez-Garcia, PhD, Francisco Vega, MD PhD, Jennifer Rose Chapman-Fredricks, MD, Izidore S. Lossos, MD

Blood (2018) 132 (Supplement 1): 674.

https://doi.org/10.1182/blood-2018-99-110825

Published: 2018

Journal Articles

Genetic Analysis of Plasmablastic Lymphomas in HIV (+) Patients Reveals Novel Driver Regulators of the Noncanonical NF-κB Pathway

Munevver Cinar, MD, Hsiao-Rong Rong, Iloabueke Chineke, MD, Abner Louissaint, Jr., MD PhD, Jennifer Rose Chapman-Fredricks, MD, Francisco Vega, MD PhD, Clifford James Gunthel, MD, Cassandra Love, Marina Mosunjac, Christopher R Flowers, MDMS, Sandeep Dave, MD, Izidore S. Lossos, MD, Leon Bernal-Mizrachi, MD

Blood (2018) 132 (Supplement 1): 1565.

https://doi.org/10.1182/blood-2018-99-118351

Published: 2018

Journal Articles

The Lymphoma Epidemiology of Outcomes (LEO) Cohort Study Reflects the Demographics and Subtypes of Patients Diagnosed with Non-Hodgkin Lymphoma in the United States

Blood (2018) 132 (Supplement 1): 1702.

https://doi.org/10.1182/blood-2018-99-114281

Published: 2018

Journal Articles

Smoothened Stabilizes and Protects TRAF6 from Proteosomal Degradation: A Novel Non-Canonical Role of Smoothened with Implications in Lymphoma Biology

Changju QU, MDPhD, Amineh Vaghefi, MD, Kranthi Kunkalla, MS, Jennifer R Chapman, MD, Yadong Liu, MD, Marzenna Blonska, PhD, Juan Pablo Alderuccio, MD, Leon Bernal-Mizrachi, MD, Izidore S Lossos, MD, Ralf Landgraf, PhD, Francisco Vega, MD PhD

Blood (2017) 130 (Supplement 1): 646.

https://doi.org/10.1182/blood.V130.Suppl_1.646.646

Published: 2017

Journal Articles

Mutational Frequency in Hispanic and Non-Hispanic Patients with Acute Myeloid Leukemia (AML): Updated Analysis of 227 Patients

Terrence J Bradley, MD, Jorge Monge, MD, Chetasi Talati, MD, Sandra Dannielle Algaze, MD BS, Christine Angela Vaupel, PhD, Jennifer R Chapman, MD, Francisco Vega, MD PhD, Jeff Hall, Jeffrey E. Lancet, MD, Eric Padron, MD, Ronan T. Swords, MD PhD FRCPI, FRCPath, Justin M Watts, MD

Blood (2017) 130 (Supplement 1): 2699.

https://doi.org/10.1182/blood.V130.Suppl_1.2699.2699

Published: 2017

Journal Articles

Upregulation of Alternatively Glycosylated Smoothened (SMO) Is Involved in Doxorubicin (DXR) Resistance in Diffuse Large B-Cell Lymphoma

Nitin Agarwal, PhD, Kranthi Kunkalla, MS, Sandra Sanchez, MD, Amineh Vaghefi, MD, Darius Juskevicius, PhD, Alexandar Tzankov, Ramiro E Verdun, PhD, Ralf Landgraf, PhD, Francisco Vega, MD PhD

Blood (2017) 130 (Supplement 1): 3839.

https://doi.org/10.1182/blood.V130.Suppl_1.3839.3839

Published: 2017

Journal Articles

The Novel Translocation t(4;15)(q31;q22) in AML Is Associated with a Proliferative Phenotype in the Presence of All-Trans Retinoic Acid (ATRA)

Justin M Watts, MD, Aymee Perez, PhD, Fernando Vargas, MD, Yao-Shan Fan, MD PhD, Alejandra Weisman, Ana Rodriguez, Omar Lopez, Francisco Vega, MD PhD, Ronan T Swords, MD PhD FRCPI, FRCPath, Arthur Zelent, PhD

Blood (2016) 128 (22): 1526.

https://doi.org/10.1182/blood.V128.22.1526.1526

Published: 2016

Journal Articles

Early Detection of Myelodysplastic Syndromes: Maximizing the Utility of Automated Hematology

Yamina Lilliana Carattini, MCLS, Terrence Bradley, MD, Fernando Vargas, MD, Justin M Watts, MD, Jennifer R Chapman, MD, German Campuzano-Zuluaga, MD, Francisco Vega, MD PhD, Deukwoo Kwon, PhD, Ronan T Swords, MD PhD FRCPI, FRCPath

Blood (2016) 128 (22): 5527.

https://doi.org/10.1182/blood.V128.22.5527.5527

Published: 2016

Journal Articles

Mutational Frequency in Hispanic Vs. Non-Hispanic Patients with Acute Myeloid Leukemia (AML)

Jorge Monge, MD, Christine Vaupel, PhD, Ronan T Swords, MD PhD FRCPI, FRCPath, Terrence Bradley, MD, Ryan Chapman, DO, Naiomi Gunaratne, Jennifer R Chapman, MD, Francisco Vega, MD PhD, Eric Padron, MD, Fernando Vargas, MD, Jeff Hall, PhD, Justin M Watts, MD

Blood (2016) 128 (22): 2796.

https://doi.org/10.1182/blood.V128.22.2796.2796

Published: 2016

Journal Articles

A Patient-Specific Ex Vivo Screening Platform for Personalized Acute Myeloid Leukemia (AML) Therapy

Diana Azzam, PhD, Claude-Henry Volmar, PhD, Al-Ali Hassan, PhD, Aymee Perez, PhD, Justin M. Watts, MD, Fernando Vargas, MD, Roy Elias, Francisco Vega, MD PhD, Arthur Zelent, PhD, Christopher R. Cogle, MD, Claes Wahlestedt, PhD, Ronan T. Swords, MDPhDFRCPI FRCPath

Blood (2015) 126 (23): 1352.

https://doi.org/10.1182/blood.V126.23.1352.1352

Published: 2015

Journal Articles

Smoothened (SMO) Is an Adaptor Protein That Recruits TRAF6 and Phospholipase C Gamma 2 (PLCg2) to Enhance the Activation of NF-Kb Signaling Pathway

Nitin Agarwal, PhD, Chae Hwa Kim, MD, Kranthi Kunkalla, MS, Gloria Yang, Youley Tjendra, MD, Yadong Liu, MD, Changju Qu, MDPhD, Francisco Vega, MD PhD

Blood (2015) 126 (23): 3907.

https://doi.org/10.1182/blood.V126.23.3907.3907

Published: 2015

Journal Articles

The Inhibitor of NF-KB Kinase, IKKβ Regulates the Transcriptional Activity of GLI1 By Blocking Its Proteasomal Degradation

Nitin Kumar Agarwal, PhD, Chae Hwa Kim, MD, Kranthi Kunkalla, MS, Izidore S. Lossos, MD, Francisco Vega, MD PhD

Blood (2014) 124 (21): 2199.

https://doi.org/10.1182/blood.V124.21.2199.2199

Published: 2014

Journal Articles

Clinical Utility of Morphological Evaluation of Day 14 Bone Marrow Biopsies in Acute Myeloid Leukemia Patients Undergoing Standard Induction Chemotherapy: Time to Change Practice?

Yehuda E. Deutsch, MD, German Campuzano-Zuluaga, MD, Matthew P Salzberg, Alexandra Gomez Arteaga, MD, Justin M. Watts, MD, Jennifer R Chapman, MD, Offiong F Ikpatt, MD, Francisco Vega, MD PhD, Ronan T Swords, MD PhD FRCPI, FRCPath

Blood (2014) 124 (21): 1004.

https://doi.org/10.1182/blood.V124.21.1004.1004

Published: 2014

Journal Articles

HDAC9 Expression Is Deregulated in Malignant B-Cell Lymphomas in Particular in Diffuse Large B Cell Lymphoma and Mantle Cell Lymphoma

Elena Cubedo, PhD, Veronica Sylvina Gil, PhD, Chae Hwa Kim, German Campuzano-Zuluaga, MD, Nitin Kumar Agarwal, PhD, Louise Howell, BSc, Kevin R. Petrie, PhD, Francisco Vega, MD PhD, Arthur Zelent, PhD

Blood (2014) 124 (21): 5374.

https://doi.org/10.1182/blood.V124.21.5374.5374

Published: 2014

Journal Articles

Transcriptional Regulation Of GLI1 , Potential New Therapeutic Target For Diffuse Large B-Cell Lymphoma

Nitin K Agarwal, PhD, Kranthi Kunkalla, MS, David H Hawke, PhD, Yadong Liu, MD, Changju Qu, MD PhD, Francisco Vega, MD, PhD

Blood (2013) 122 (21): 2513.

https://doi.org/10.1182/blood.V122.21.2513.2513

Published: 2013

Journal Articles

Smoothened (SMO) Activates NF-Kb Pathway Through Activation of PKCβ/CARMA1 and TRAF6 Stabilization in Diffuse Large B-Cell Lymphoma

Changju Qu, MD PhD, Yadong Liu, MD, Kranthi Kunkalla, MS, Nitin K Agarwal, PhD, Francisco Vega, MD, PhD

Blood (2012) 120 (21): 1298.

https://doi.org/10.1182/blood.V120.21.1298.1298

Published: 2012

NARROW

Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma

NPM-ALK Upregulates Jab1/Csn5 through STAT3 Activation in Anaplastic Large Cell Lymphoma: A Novel Function of NPM-ALK That Contributes to PD1/PD-L1 Immune Checkpoint Regulation

CRISPR/Cas9 Generation of Npm1-Alk in Transplantable Murine Hematopoietic Stem Cells Accurately Models ALK-Positive Lymphoma in Recipients

Genetic Landscape of Ocular Adnexa Extranodal Marginal Zone Lymphoma

LMO2 Facilitates Synthetic Lethality after PARP Inhibition (PARPi) in Diffuse Large B-Cell Lymphoma (DLBCL)

Genetic Analysis of Plasmablastic Lymphomas in HIV (+) Patients Reveals Novel Driver Regulators of the Noncanonical NF-κB Pathway

The Lymphoma Epidemiology of Outcomes (LEO) Cohort Study Reflects the Demographics and Subtypes of Patients Diagnosed with Non-Hodgkin Lymphoma in the United States

Smoothened Stabilizes and Protects TRAF6 from Proteosomal Degradation: A Novel Non-Canonical Role of Smoothened with Implications in Lymphoma Biology

Mutational Frequency in Hispanic and Non-Hispanic Patients with Acute Myeloid Leukemia (AML): Updated Analysis of 227 Patients

Upregulation of Alternatively Glycosylated Smoothened (SMO) Is Involved in Doxorubicin (DXR) Resistance in Diffuse Large B-Cell Lymphoma

The Novel Translocation t(4;15)(q31;q22) in AML Is Associated with a Proliferative Phenotype in the Presence of All-Trans Retinoic Acid (ATRA)

Early Detection of Myelodysplastic Syndromes: Maximizing the Utility of Automated Hematology

Mutational Frequency in Hispanic Vs. Non-Hispanic Patients with Acute Myeloid Leukemia (AML)

A Patient-Specific Ex Vivo Screening Platform for Personalized Acute Myeloid Leukemia (AML) Therapy

Smoothened (SMO) Is an Adaptor Protein That Recruits TRAF6 and Phospholipase C Gamma 2 (PLCg2) to Enhance the Activation of NF-Kb Signaling Pathway

The Inhibitor of NF-KB Kinase, IKKβ Regulates the Transcriptional Activity of GLI1 By Blocking Its Proteasomal Degradation

Clinical Utility of Morphological Evaluation of Day 14 Bone Marrow Biopsies in Acute Myeloid Leukemia Patients Undergoing Standard Induction Chemotherapy: Time to Change Practice?

HDAC9 Expression Is Deregulated in Malignant B-Cell Lymphomas in Particular in Diffuse Large B Cell Lymphoma and Mantle Cell Lymphoma

Transcriptional Regulation Of GLI1 , Potential New Therapeutic Target For Diffuse Large B-Cell Lymphoma

Smoothened (SMO) Activates NF-Kb Pathway Through Activation of PKCβ/CARMA1 and TRAF6 Stabilization in Diffuse Large B-Cell Lymphoma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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