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Journal Articles

Cryopreserved Platelets Retain Agonist Responsiveness and Support for Factor VIII Function

Valerie Anne Novakovic, MS, Madhumouli Chatterjee, PhD, Gary E Gilbert, MD

Blood (2020) 136 (Supplement 1): 3–4.

https://doi.org/10.1182/blood-2020-143366

Published: 2020

Journal Articles

Platelet-Based Factor VIII Activity Is Inhibited By Anti-C2 Domain Antibodies That Donâ€™t Significantly Inhibit Factor VIII Activity in a Standard Assay

Madhumouli Chatterjee, PhD, Shannon L. Meeks, MD, Valerie Anne Novakovic, MS, John S. Lollar, MD, Gary E Gilbert, MD

Blood (2017) 130 (Supplement 1): 2345.

https://doi.org/10.1182/blood.V130.Suppl_1.2345.2345

Published: 2017

Journal Articles

Factor VIII Binds to an Acidic Fibrinogen Variant, a Critical Component of the High-Affinity Fibrin Binding Site, Resulting in Increased Cofactor Activity

Valerie Anne Novakovic, MS, Gary E Gilbert, MD

Blood (2017) 130 (Supplement 1): 1064.

https://doi.org/10.1182/blood.V130.Suppl_1.1064.1064

Published: 2017

Journal Articles

Platelet Membranes and Activation Pathway Determine Inhibitory Activity of Anti-Factor VIII C2 Domain Antibodies

Madhumouli Chatterjee, PhD, Shannon L. Meeks, MD, Valerie Anne Novakovic, MS, Pete Lollar, MD, Gary E. Gilbert, MD

Blood (2016) 128 (22): 2567.

https://doi.org/10.1182/blood.V128.22.2567.2567

Published: 2016

Journal Articles

Platelet Phosphatidylserine Exposure, Survival and Blood Coagulation in Mice Lacking TMEM16F

Gary E. Gilbert, MD, Colin Kretz, PhD, David Ginsburg, MD, Valerie Anne Novakovic, MS

Blood (2015) 126 (23): SCI-32.

https://doi.org/10.1182/blood.V126.23.SCI-32.SCI-32

Published: 2015

Journal Articles

TMEM16F Deficiency Causes a Strain-Dependent Lethality in Mice and Reduced Phosphatidylserine Exposure on Heterozygous As Well As Homozygous Deficient Mouse Platelets

Colin A Kretz, PhD, Valerie A Novakovic, M.S., Anna Kiseleva, Audrey C.A. Cleuren, PhD, Rami Khoriaty, MD, Elizabeth Adams, PhD, David Ginsburg, MD, Gary E. Gilbert, MD

Blood (2014) 124 (21): 4157.

https://doi.org/10.1182/blood.V124.21.4157.4157

Published: 2014

Journal Articles

Daunorubicin Induces Procoagulant Activity of Cultured Endothelial Cells through Phosphatidylserine Exposure and Microparticles Release

Yueyue Fu, MD, Huibo Li, MD, Wen Li, MD, Xiushuai Dong, MD, Jinxiao Hou, MD, Rui Xie, MD, Chunyan Gao, MD, Xue Yang, MD, Jin Zhou, MD, PhD, Gary E. Gilbert, MD, Jialan Shi, MD, PhD

Blood (2010) 116 (21): 5185.

https://doi.org/10.1182/blood.V116.21.5185.5185

Published: 2010

Journal Articles

Neutrophils Clearance by Endothelial Cells Regulates Homeostasis and Coagulation.

Wen Li, MD, Shuchuan Liu, MD, Yueyue Fu, MD, Jinxiao Hou, MD, Xiushuai Dong, MD, Rui Xie, MD, Xue Yang, MD, Chunyan Gao, MD, Jin Zhou, MD, PhD, Gary E. Gilbert, MD, Jialan Shi, MD, PhD

Blood (2010) 116 (21): 3782.

https://doi.org/10.1182/blood.V116.21.3782.3782

Published: 2010

Journal Articles

Focal Phosphatidylserine Exposure on Stressed Endothelial Cells In Relation to Membrane Topology: A Potential Basis for Compartmentalization of Procoagulant and Anticoagulant Activities

Dessislava N. Nikova, PhD, Gary E. Gilbert, MD

Blood (2010) 116 (21): 4321.

https://doi.org/10.1182/blood.V116.21.4321.4321

Published: 2010

Journal Articles

Effect of Membrane Binding Upon Intramolecular Dynamics of the Factor VIII C2 Domain.

Dennis Pantazatos, PhD, Christopher Gessner, Virgil Woods, MD, Gary E. Gilbert, MD

Blood (2009) 114 (22): 3168.

https://doi.org/10.1182/blood.V114.22.3168.3168

Published: 2009

Journal Articles

Lactadherin as a Probe for Phosphatidylserine Exposure and as An Anticoagulant for the Procoagulant Activity in the Study of Stored Platelets.

Jin Zhou, Jinxiao Hou, Wen Li, Xiaoqian Zhang, Yueyue Fu, Huibo Li, Rui Xie, Zhuo Zhang, Gary E. Gilbert, MD, Jialan Shi

Blood (2009) 114 (22): 3150.

https://doi.org/10.1182/blood.V114.22.3150.3150

Published: 2009

Journal Articles

Membrane-Interactive Amino Acids in the Factor VIII C1 Domain Are Cooperative with C2 Domain Epitopes for Membrane Binding and Cofactor Function.

Junhong Lu, Ph.D., Steven W. Pipe, MD, Hongzhi Miao, Marc Jacquemin, Ph.D., Gary E. Gilbert, MD

Blood (2009) 114 (22): 848.

https://doi.org/10.1182/blood.V114.22.848.848

Published: 2009

Journal Articles

The Factor VIIII C2 Domain Shows Stereospecificity for Phosphatidyl-L-Serine and Increases Factor IXa Activity

Valerie A Novakovic, M.S., James D Baleja, Ph.D., Gary E. Gilbert, MD

Blood (2008) 112 (11): 3090.

https://doi.org/10.1182/blood.V112.11.3090.3090

Published: 2008

Journal Articles

The Mutations SER2117→LEU, and TRP/TRP2063/64→MET/PHE in the Hydrophobic Spikes of the Factor V C2 Domain Lead to Tenacious Phospholipid Binding and Suggest a Mechanism through Which Phosphatidylserine Activates the Prothrombinase Complex.

Gary E. Gilbert, MD, Valerie A. Novakovic, M.S., Randal J. Kaufman, Ph.D., Hongzhi Miao, B.S., Steven W. Pipe, M.D.

Blood (2007) 110 (11): 2703.

https://doi.org/10.1182/blood.V110.11.2703.2703

Published: 2007

Journal Articles

Regulated Phosphatidylserine Exposure on Platelets Mediates Fibrin Formation in Hemostasis and Thrombosis.

Jialan Shi, MD, PhD, Steven W. Pipe, MD, Jan T. Rasmussen, PhD, Christian W. Heegaard, PhD, Gary E. Gilbert, MD

Blood (2005) 106 (11): 1645.

https://doi.org/10.1182/blood.V106.11.1645.1645

Published: 2005

NARROW

Cryopreserved Platelets Retain Agonist Responsiveness and Support for Factor VIII Function

Platelet-Based Factor VIII Activity Is Inhibited By Anti-C2 Domain Antibodies That Donâ€™t Significantly Inhibit Factor VIII Activity in a Standard Assay

Factor VIII Binds to an Acidic Fibrinogen Variant, a Critical Component of the High-Affinity Fibrin Binding Site, Resulting in Increased Cofactor Activity

Platelet Membranes and Activation Pathway Determine Inhibitory Activity of Anti-Factor VIII C2 Domain Antibodies

Platelet Phosphatidylserine Exposure, Survival and Blood Coagulation in Mice Lacking TMEM16F

TMEM16F Deficiency Causes a Strain-Dependent Lethality in Mice and Reduced Phosphatidylserine Exposure on Heterozygous As Well As Homozygous Deficient Mouse Platelets

Daunorubicin Induces Procoagulant Activity of Cultured Endothelial Cells through Phosphatidylserine Exposure and Microparticles Release

Neutrophils Clearance by Endothelial Cells Regulates Homeostasis and Coagulation.

Focal Phosphatidylserine Exposure on Stressed Endothelial Cells In Relation to Membrane Topology: A Potential Basis for Compartmentalization of Procoagulant and Anticoagulant Activities

Effect of Membrane Binding Upon Intramolecular Dynamics of the Factor VIII C2 Domain.

Lactadherin as a Probe for Phosphatidylserine Exposure and as An Anticoagulant for the Procoagulant Activity in the Study of Stored Platelets.

Membrane-Interactive Amino Acids in the Factor VIII C1 Domain Are Cooperative with C2 Domain Epitopes for Membrane Binding and Cofactor Function.

The Factor VIIII C2 Domain Shows Stereospecificity for Phosphatidyl-L-Serine and Increases Factor IXa Activity

The Mutations SER2117→LEU, and TRP/TRP2063/64→MET/PHE in the Hydrophobic Spikes of the Factor V C2 Domain Lead to Tenacious Phospholipid Binding and Suggest a Mechanism through Which Phosphatidylserine Activates the Prothrombinase Complex.

Regulated Phosphatidylserine Exposure on Platelets Mediates Fibrin Formation in Hemostasis and Thrombosis.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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