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Journal Articles

Combination of Menin and IDH Mutant Inhibition in Acute Myeloid Leukemia

James J. Yoon, Hongzhi Miao, Trupta Purohit, Dong Chen, Tomasz Cierpicki, Jolanta Grembecka

Blood (2022) 140 (Supplement 1): 5946.

https://doi.org/10.1182/blood-2022-168834

Published: 2022

Journal Articles

Combinatorial treatment with menin and FLT3 inhibitors induces complete remission in AML models with activating FLT3 mutations

Hongzhi Miao, EunGi Kim, Dong Chen, Trupta Purohit, Katarzyna Kempinska, James Ropa, Szymon Klossowski, Winifred Trotman, Gwenn Danet-Desnoyers, Tomasz Cierpicki, Jolanta Grembecka

Blood (2020) 136 (25): 2958–2963.

https://doi.org/10.1182/blood.2020006575

Published: 2020

Includes: Supplemental data

Journal Articles

HOXA9 Recruitment of Methyltransferase Complexes Alters Enhancer Landscape during Leukemic Transformation

Yuqing Sun, PhD, Hongzhi Miao, Zhenhua Zou, PhD, Bo Zhou, PhD, Kai Ge, PhD, Gregory Dressler, PhD, Yali Dou, PhD, Jay Hess, MD

Blood (2017) 130 (Supplement 1): 783.

https://doi.org/10.1182/blood.V130.Suppl_1.783.783

Published: 2017

Journal Articles

The same site on the integrase-binding domain of lens epithelium–derived growth factor is a therapeutic target for MLL leukemia and HIV

Marcelo J. Murai, Jonathan Pollock, Shihan He, Hongzhi Miao, Trupta Purohit, Adam Yokom, Jay L. Hess, Andrew G. Muntean, Jolanta Grembecka, Tomasz Cierpicki

Blood (2014) 124 (25): 3730–3737.

https://doi.org/10.1182/blood-2014-01-550079

Published: 2014

Includes: Supplemental data

Journal Articles

Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity

Gary E. Gilbert, Valerie A. Novakovic, Randal J. Kaufman, Hongzhi Miao, Steven W. Pipe

Blood (2012) 120 (9): 1923–1932.

https://doi.org/10.1182/blood-2012-01-408245

Published: 2012

Includes: Supplemental data

Journal Articles

Elucidation of the Roles of Individual Asparagine-Linked Glycans Outside of the B Domain on Factor VIII Secretion

Sundar Rajan Selvaraj, PhD, Hongzhi Miao, MS, Steven Pipe, MD

Blood (2011) 118 (21): 2238.

https://doi.org/10.1182/blood.V118.21.2238.2238

Published: 2011

Journal Articles

Conservative Mutations in the Membrane-Binding Motif of Factor V C2 Domain to Residues of Pseudonaja Textilis Venom Factor V Confer Phosphatidylserine-Independent Activity

Valerie A Novakovic, M.S., Hongzhi Miao, Steven Pipe, MD, Gary E. Gilbert, M.D.

Blood (2011) 118 (21): 2243.

https://doi.org/10.1182/blood.V118.21.2243.2243

Published: 2011

Journal Articles

A membrane-interactive surface on the factor VIII C1 domain cooperates with the C2 domain for cofactor function

Junhong Lü, Steven W. Pipe, Hongzhi Miao, Marc Jacquemin, Gary E. Gilbert

Blood (2011) 117 (11): 3181–3189.

https://doi.org/10.1182/blood-2010-08-301663

Published: 2011

Journal Articles

Endoplasmic Reticulum to Mitochondria Ca 2+ Signaling Inhibits Factor VIII Secretion and Mediates Oxidative Stress and Apoptosis Upon Factor VIII Expression

Jyoti Malhotra, Mon Xiong, Hongzhi Miao, Steven Pipe, Randal J. Kaufman, PhD

Blood (2010) 116 (21): 2212.

https://doi.org/10.1182/blood.V116.21.2212.2212

Published: 2010

Journal Articles

Membrane-Interactive Amino Acids in the Factor VIII C1 Domain Are Cooperative with C2 Domain Epitopes for Membrane Binding and Cofactor Function.

Junhong Lu, Ph.D., Steven W. Pipe, MD, Hongzhi Miao, Marc Jacquemin, Ph.D., Gary E. Gilbert, MD

Blood (2009) 114 (22): 848.

https://doi.org/10.1182/blood.V114.22.848.848

Published: 2009

Journal Articles

Strategies to Enhance the Efficacy of Platelet-Derived Factor (F) VIII: Studies with Inactivation Resistant FVIII (IR8) and Canine FVIII in Hemophilia A Mice.

Teshell K. Greene, BS, Cheng Wang, Jessica Hirsch, BS, Hongzhi Miao, Steven W. Pipe, MD, M. Anna Kowalska, PhD, Mortimer Poncz, MD

Blood (2009) 114 (22): 3496.

https://doi.org/10.1182/blood.V114.22.3496.3496

Published: 2009

Journal Articles

The Mutations SER2117→LEU, and TRP/TRP2063/64→MET/PHE in the Hydrophobic Spikes of the Factor V C2 Domain Lead to Tenacious Phospholipid Binding and Suggest a Mechanism through Which Phosphatidylserine Activates the Prothrombinase Complex.

Gary E. Gilbert, MD, Valerie A. Novakovic, M.S., Randal J. Kaufman, Ph.D., Hongzhi Miao, B.S., Steven W. Pipe, M.D.

Blood (2007) 110 (11): 2703.

https://doi.org/10.1182/blood.V110.11.2703.2703

Published: 2007

NARROW

Combination of Menin and IDH Mutant Inhibition in Acute Myeloid Leukemia

Combinatorial treatment with menin and FLT3 inhibitors induces complete remission in AML models with activating FLT3 mutations

HOXA9 Recruitment of Methyltransferase Complexes Alters Enhancer Landscape during Leukemic Transformation

The same site on the integrase-binding domain of lens epithelium–derived growth factor is a therapeutic target for MLL leukemia and HIV

Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity

Elucidation of the Roles of Individual Asparagine-Linked Glycans Outside of the B Domain on Factor VIII Secretion

Conservative Mutations in the Membrane-Binding Motif of Factor V C2 Domain to Residues of Pseudonaja Textilis Venom Factor V Confer Phosphatidylserine-Independent Activity

A membrane-interactive surface on the factor VIII C1 domain cooperates with the C2 domain for cofactor function

Endoplasmic Reticulum to Mitochondria Ca 2+ Signaling Inhibits Factor VIII Secretion and Mediates Oxidative Stress and Apoptosis Upon Factor VIII Expression

Membrane-Interactive Amino Acids in the Factor VIII C1 Domain Are Cooperative with C2 Domain Epitopes for Membrane Binding and Cofactor Function.

Strategies to Enhance the Efficacy of Platelet-Derived Factor (F) VIII: Studies with Inactivation Resistant FVIII (IR8) and Canine FVIII in Hemophilia A Mice.

The Mutations SER2117→LEU, and TRP/TRP2063/64→MET/PHE in the Hydrophobic Spikes of the Factor V C2 Domain Lead to Tenacious Phospholipid Binding and Suggest a Mechanism through Which Phosphatidylserine Activates the Prothrombinase Complex.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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