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Journal Articles

Local Oxygen Dictates Hematopoietic Cell Growth and Function

James Ropa, Sarah Gutch, Gracie Whitacre, Lindsay Beasley, Wouter Van't Hof, Mark H Kaplan, Maegan L Capitano

Blood (2023) 142 (Supplement 1): 1307.

https://doi.org/10.1182/blood-2023-191081

Published: 2023

Journal Articles

The DPP4 Dependent Transcriptome Identifies Pathways to Improve Mouse Hematopoietic Cell Function

James Ropa, Scott Cooper, Maegan L Capitano, Mark H Kaplan

Blood (2023) 142 (Supplement 1): 3420.

https://doi.org/10.1182/blood-2023-191156

Published: 2023

Journal Articles

Maternal Obesity Causes Sex Specific Long-Term Hematopoietic and Metabolic Defects

Merve Denizli, James Ropa, Lindsay Beasley, Kelli DeVanna, Laura S. Haneline, Kok Lim Kua, Maegan L Capitano

Blood (2023) 142 (Supplement 1): 31.

https://doi.org/10.1182/blood-2023-189261

Published: 2023

Journal Articles

Recovery of Highly Functional Human Hematopoietic Stem and Progenitor Cells from 27-Year Old Cryopreserved Umbilical Cord Blood

Hal E. Broxmeyer, Larry L Luchsinger, Rona S Weinberg, Alexandra Jimenez, Emeline Masson Frenet, Mark Kaplan, Scott Cooper, James Ropa

Blood (2022) 140 (Supplement 1): 10437–10438.

https://doi.org/10.1182/blood-2022-170272

Published: 2022

Journal Articles

Extracellular DEK Activates NRF2 Antioxidant Targets and Drives Expansion of Functional and ROS-Low Human Hematopoietic Stem Cells

James Ropa, Sarah Gutch, Lindsay Beasley, Paola Aguilar Neuville, Scott Cooper, Di Cao, Wouter van't Hof, Maureen Legendre, Mark Kaplan, David M Markovitz, Maegan L. Capitano

Blood (2022) 140 (Supplement 1): 8576–8577.

https://doi.org/10.1182/blood-2022-170089

Published: 2022

Journal Articles

Physioxia-induced downregulation of Tet2 in hematopoietic stem cells contributes to enhanced self-renewal

Arafat Aljoufi, Chi Zhang, James Ropa, Wennan Chang, Lakshmi Reddy Palam, Scott Cooper, Baskar Ramdas, Maegan L. Capitano, Hal E. Broxmeyer, Reuben Kapur

Blood (2022) 140 (11): 1263–1277.

https://doi.org/10.1182/blood.2022015499

Published: 2022

Includes: Supplemental data

Journal Articles

Extracellular DEK Treatment Mimics Hypoxic Blockade of Extra Physiologic Oxygen Stress in Human and Mouse Hematopoietic Cells

James Ropa, Scott Cooper, Lindsay Beasley, David M Markovitz, Hal E. Broxmeyer, Maegan L. Capitano

Blood (2021) 138 (Supplement 1): 2152.

https://doi.org/10.1182/blood-2021-151171

Published: 2021

Journal Articles

Combinatorial treatment with menin and FLT3 inhibitors induces complete remission in AML models with activating FLT3 mutations

Hongzhi Miao, EunGi Kim, Dong Chen, Trupta Purohit, Katarzyna Kempinska, James Ropa, Szymon Klossowski, Winifred Trotman, Gwenn Danet-Desnoyers, Tomasz Cierpicki, Jolanta Grembecka

Blood (2020) 136 (25): 2958–2963.

https://doi.org/10.1182/blood.2020006575

Published: 2020

Includes: Supplemental data

Journal Articles

Leptin Receptor As a Marker for a Subset of Long-Term Functional Hematopoietic Stem Cells

Thao Trinh, BS, James Ropa, BS, MSc, PhD, Arafat Aljoufi, MD, Scott Cooper, MS, Edward F. Srour, PhD, Anthony Sinn, BS, Hal E. Broxmeyer, PhD

Blood (2020) 136 (Supplement 1): 31–32.

https://doi.org/10.1182/blood-2020-139595

Published: 2020

Journal Articles

Sars-Cov-2 Spike Protein Induces Cellular Changes in Primitive and Mature Hematopoietic Cells

James Ropa, BS, MSc, PhD, Scott Cooper, MS, Maegan L. Capitano, PhD, Hal E. Broxmeyer, PhD

Blood (2020) 136 (Supplement 1): 25–26.

https://doi.org/10.1182/blood-2020-142415

Published: 2020

Journal Articles

SETDB1 Mediated H3K9 Methylation Suppresses MLL-Fusion Target Expression and Leukemic Transformation

Andrew G. Muntean, PhD, James Ropa, Nirmalya SAHA, PhD MSc, BSc, Hsiang-Yu Hu, BS, Justin Serio, Lili Zhao, Venkatesha Basrur, Alexei Nesvizhskii, Ivan Maillard, MD PhD

Blood (2019) 134 (Supplement_1): 110.

https://doi.org/10.1182/blood-2019-122610

Published: 2019

Journal Articles

SETDB1 Represses Hox Gene Expression and Suppresses Acute Myeloid Leukemia

James Ropa, BS, Nirmalya SAHA, PhD, Andrew G. Muntean, PhD

Blood (2018) 132 (Supplement 1): 1320.

https://doi.org/10.1182/blood-2018-99-117690

Published: 2018

Journal Articles

The PAF1c Subunit Cdc73 Is Essential for Hematopoiesis and Displays Differential Gene Regulation in MLL-AF9 Driven Leukemia

Nirmalya SAHA, PhD MSc, BSc, James Ropa, BS, Lili Chen, PhD, Hsiang-Yu Hu, BS, Maria Mysliwski, Ann Friedman, BS, Ivan Maillard, MD, Andrew G. Muntean, PhD

Blood (2018) 132 (Supplement 1): 1280.

https://doi.org/10.1182/blood-2018-99-118703

Published: 2018

Journal Articles

The AF9-Binding Domain of DOT1L Is Critical for Its Recruitment By MLL Fusion Proteins in Leukemia and Contributes to Its Functions in Normal Hematopoiesis

Sierrah Marie Grigsby, BS, James Ropa, BS, Justin Serio, BS, Jennifer Chase, PhD, Chenxi Shen, PhD, Andrew G. Muntean, PhD, Ivan Maillard, MD PhD, Zaneta Nikolovska-Coleska, PhD

Blood (2017) 130 (Supplement 1): 3785.

https://doi.org/10.1182/blood.V130.Suppl_1.3785.3785

Published: 2017

Journal Articles

The PAF Complex Regulation of Prmt5 Facilitates Leukemic Progression

Justin Serio, B.S., Wei Chen, Maria Mysliwski, Lili Chen, PhD, James Ropa, B.S., Jingya Wang, PhD, Andrew G. Muntean, PhD

Blood (2016) 128 (22): 3914.

https://doi.org/10.1182/blood.V128.22.3914.3914

Published: 2016

Journal Articles

Hyperactive Ptpn11 Mutations Alters Leukemic Stem Cell Frequency through Mcl-1 Overexpression

Lili Chen, PhD, Wei Chen, PhD, Maria Mysliwski, Justin Serio, James Ropa, Fardokht Abulwerdi, Rebecca J. Chan, MD PhD, Jay P. Patel, Martin S. Tallman, MD, Elisabeth M. Paietta, PhD, Ari M Melnick, MD, Ross L. Levine, MD, Omar Abdel-Wahab, MD, Zaneta Nikolovska-Coleska, PhD, Andrew G. Muntean, PhD

Blood (2014) 124 (21): 3565.

https://doi.org/10.1182/blood.V124.21.3565.3565

Published: 2014

NARROW

Local Oxygen Dictates Hematopoietic Cell Growth and Function

The DPP4 Dependent Transcriptome Identifies Pathways to Improve Mouse Hematopoietic Cell Function

Maternal Obesity Causes Sex Specific Long-Term Hematopoietic and Metabolic Defects

Recovery of Highly Functional Human Hematopoietic Stem and Progenitor Cells from 27-Year Old Cryopreserved Umbilical Cord Blood

Extracellular DEK Activates NRF2 Antioxidant Targets and Drives Expansion of Functional and ROS-Low Human Hematopoietic Stem Cells

Physioxia-induced downregulation of Tet2 in hematopoietic stem cells contributes to enhanced self-renewal

Extracellular DEK Treatment Mimics Hypoxic Blockade of Extra Physiologic Oxygen Stress in Human and Mouse Hematopoietic Cells

Combinatorial treatment with menin and FLT3 inhibitors induces complete remission in AML models with activating FLT3 mutations

Leptin Receptor As a Marker for a Subset of Long-Term Functional Hematopoietic Stem Cells

Sars-Cov-2 Spike Protein Induces Cellular Changes in Primitive and Mature Hematopoietic Cells

SETDB1 Mediated H3K9 Methylation Suppresses MLL-Fusion Target Expression and Leukemic Transformation

SETDB1 Represses Hox Gene Expression and Suppresses Acute Myeloid Leukemia

The PAF1c Subunit Cdc73 Is Essential for Hematopoiesis and Displays Differential Gene Regulation in MLL-AF9 Driven Leukemia

The AF9-Binding Domain of DOT1L Is Critical for Its Recruitment By MLL Fusion Proteins in Leukemia and Contributes to Its Functions in Normal Hematopoiesis

The PAF Complex Regulation of Prmt5 Facilitates Leukemic Progression

Hyperactive Ptpn11 Mutations Alters Leukemic Stem Cell Frequency through Mcl-1 Overexpression

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American Society of Hematology

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ASH Publications

American Society of Hematology

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