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Maegan L. Capitano
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Journal Articles

The DPP4 Dependent Transcriptome Identifies Pathways to Improve Mouse Hematopoietic Cell Function

James Ropa, Scott Cooper, Maegan L Capitano, Mark H Kaplan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3420.
https://doi.org/10.1182/blood-2023-191156
Published: 2023
Journal Articles

Local Oxygen Dictates Hematopoietic Cell Growth and Function

James Ropa, Sarah Gutch, Gracie Whitacre, Lindsay Beasley, Wouter Van't Hof, Mark H Kaplan, Maegan L Capitano
Journal: Blood
Blood (2023) 142 (Supplement 1): 1307.
https://doi.org/10.1182/blood-2023-191081
Published: 2023
Journal Articles

Maternal Obesity Causes Sex Specific Long-Term Hematopoietic and Metabolic Defects

Merve Denizli, James Ropa, Lindsay Beasley, Kelli DeVanna, Laura S. Haneline, Kok Lim Kua, Maegan L Capitano
Journal: Blood
Blood (2023) 142 (Supplement 1): 31.
https://doi.org/10.1182/blood-2023-189261
Published: 2023
Journal Articles

PI3K Signaling Is Essential for Leukemic Transformation of Tet2 Mutated Pre-Leukemic Hematopoietic Stem Cells

Lakshmi Reddy Palam, Baskar Ramdas, Katelyn Pickerell, Maegan L. Capitano, Reuben Kapur
Journal: Blood
Blood (2022) 140 (Supplement 1): 5736.
https://doi.org/10.1182/blood-2022-166430
Published: 2022
Journal Articles

Extracellular DEK Activates NRF2 Antioxidant Targets and Drives Expansion of Functional and ROS-Low Human Hematopoietic Stem Cells

James Ropa, Sarah Gutch, Lindsay Beasley, Paola Aguilar Neuville, Scott Cooper, Di Cao, Wouter van't Hof, Maureen Legendre, Mark Kaplan, David M Markovitz, Maegan L. Capitano
Journal: Blood
Blood (2022) 140 (Supplement 1): 8576–8577.
https://doi.org/10.1182/blood-2022-170089
Published: 2022
Journal Articles

Physioxia-induced downregulation of Tet2 in hematopoietic stem cells contributes to enhanced self-renewal

Arafat Aljoufi, Chi Zhang, James Ropa, Wennan Chang, Lakshmi Reddy Palam, Scott Cooper, Baskar Ramdas, Maegan L. Capitano, Hal E. Broxmeyer, Reuben Kapur
Journal: Blood
Blood (2022) 140 (11): 1263–1277.
https://doi.org/10.1182/blood.2022015499
Published: 2022
Includes: Supplemental data
Journal Articles

Immunotherapy Targeting ST2/IL-33 Signaling in Myeloid Leukemia Stem Cells

Denggang Fu, Hua Jiang, Alan Long, Hong fen Guo, Maegan L. Capitano, Baskar Ramdas, Reuben Kapur, Nai-Kong V. Cheung, Sophie Paczesny
Journal: Blood
Blood (2021) 138 (Supplement 1): 23.
https://doi.org/10.1182/blood-2021-149672
Published: 2021
Journal Articles

Extracellular DEK Treatment Mimics Hypoxic Blockade of Extra Physiologic Oxygen Stress in Human and Mouse Hematopoietic Cells

James Ropa, Scott Cooper, Lindsay Beasley, David M Markovitz, Hal E. Broxmeyer, Maegan L. Capitano
Journal: Blood
Blood (2021) 138 (Supplement 1): 2152.
https://doi.org/10.1182/blood-2021-151171
Published: 2021
Journal Articles

Sars-Cov-2 Spike Protein Induces Cellular Changes in Primitive and Mature Hematopoietic Cells

James Ropa, BS, MSc, PhD, Scott Cooper, MS, Maegan L. Capitano, PhD, Hal E. Broxmeyer, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-142415
Published: 2020
Journal Articles

Hematopoietic Stem and Progenitor Cells Manifest Direct Migration Towards Secreted DEK in a CXCR2- and G Protein Signaling-Dependent Manner

Maegan L. Capitano, PhD, Yasser Sammour, Maureen Legendre, Scott Cooper, MS, David Markovitz, MD, Hal E. Broxmeyer, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1196.
https://doi.org/10.1182/blood-2019-128738
Published: 2019
Journal Articles

Collection and Processing of Bone Marrow at 3% Oxygen Significantly Alters the Manifestation of Aged Mouse Hematopoietic Stem Cell Phenotype

Maegan L. Capitano, PhD, Scott Cooper, M.S., Bin Guo, PhD, Xinxin Huang, PhD, Carol Sampson, MS, Safa Mohamad, Edward F. Srour, PhD, Christie M. Orschell, PhD, Hal E. Broxmeyer, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1202.
https://doi.org/10.1182/blood-2019-128642
Published: 2019
Journal Articles

Chromatin Remodeling Subunit Brm Regulates Hematopoietic Stem Cell Self-Renewal By Limiting Intracellular Valine Levels

Samisubbu R Naidu, PhD, Maegan L. Capitano, PhD, Scott Cooper, MS, Xinxin Huang, PhD, Hal E. Broxmeyer, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3702.
https://doi.org/10.1182/blood-2019-128867
Published: 2019
Journal Articles

CD166 Engagement Augments Mouse and Human Hematopoietic Stem and Progenitor Function Via Activation of Stem Cell-Associated and Cell Cycle Pathways

Joydeep Ghosh, PhD, Jing Zhang, PhD, Chi Zhang, PhD, Xinxin Huang, PhD, Safa F. Mohamad, MS, Maegan L. Capitano, PhD, Andrea M. Gunawan, Scott Cooper, MS, Bin Guo, PhD, Qingchun Cai, PhD, Hal E. Broxmeyer, PhD, Edward F. Srour, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1282.
https://doi.org/10.1182/blood-2018-99-119251
Published: 2018
Journal Articles

Nitric Oxide Promotes Human Hematopoietic Stem Cell Homing and Engraftment Via cGMP-Pkg Signaling

Xinxin Huang, PhD, Bin Guo, PhD, Maegan L. Capitano, PhD, Hal E. Broxmeyer, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 807.
https://doi.org/10.1182/blood-2018-99-112993
Published: 2018
Journal Articles

Erythropoietin modulation is associated with improved homing and engraftment after umbilical cord blood transplantation

Omar S. Aljitawi, Soumen Paul, Avishek Ganguly, Tara L. Lin, Sid Ganguly, George Vielhauer, Maegan L. Capitano, Amy Cantilena, Brea Lipe, Jonathan D. Mahnken, Amanda Wise, Abigale Berry, Anurag K. Singh, Leyla Shune, Christopher Lominska, Sunil Abhyankar, Dennis Allin, Mary Laughlin, Joseph P. McGuirk, Hal E. Broxmeyer
Journal: Blood
Blood (2016) 128 (25): 3000–3010.
https://doi.org/10.1182/blood-2016-05-715292
Published: 2016
Includes: Supplemental data
Journal Articles

Re-Evaluation of Age-Related Dysregulation of Hematopoiesis Based on Oxygen Induced Changes Associated with Cell Collection/Processing in Ambient Air

Hal E. Broxmeyer, PhD, Maegan L. Capitano, PhD, Heather A. O'leary, PhD, Scott Cooper, MAS, Hui Lin Chua, PhD, Artur Plett, PhD, Christie M. Orschell, PhD
Journal: Blood
Blood (2016) 128 (22): 5051.
https://doi.org/10.1182/blood.V128.22.5051.5051
Published: 2016
Journal Articles

DEK Regulates Hematopoietic Stem and Progenitor Cell Fate By Activating AKT and ERK Mediated Signaling through CXCR2/Heparan Sulfate Proteoglycans

Maegan L. Capitano, PhD, Nirit Mor-Vaknin, Maureen Legendre, Scott Cooper, MAS, David Markovitz, MD, Hal E. Broxmeyer, PhD
Journal: Blood
Blood (2016) 128 (22): 2645.
https://doi.org/10.1182/blood.V128.22.2645.2645
Published: 2016
Journal Articles

Impact of Erythropoietin Modulation Using Hyperbaric Oxygen on Umbilical Cord Blood CD34+ Cell Homing

Omar S. Aljitawi, MD, Tara L. Lin, MD, George Vielhauer, Aaron Cheung, Maegan L. Capitano, PhD, Dandan Li, MS, Amanda Wise, Brea C. Lipe, MD, Soumen Paul, PhD, Mary Laughlin, Hal E. Broxmeyer, PhD
Journal: Blood
Blood (2015) 126 (23): 1870.
https://doi.org/10.1182/blood.V126.23.1870.1870
Published: 2015
Journal Articles

Recombinant DEK Enhances Ex Vivo expansion of Human Cord Blood and Mouse Bone Marrow Hematopoietic Stem Cells in a CXCR2- and Hspg-Dependent Manner

Maegan L. Capitano, PhD, Nirit Mor-Vaknin, Maureen Legendre, Scott Cooper, MAS, David Markovitz, MD, Hal E. Broxmeyer, PhD
Journal: Blood
Blood (2015) 126 (23): 779.
https://doi.org/10.1182/blood.V126.23.779.779
Published: 2015
Journal Articles

Role for Megakaryocyte Phosphatidylinositol Transfer Proteins-Alpha and -Beta in TGF Beta-Mediated Regulation of Hematopoietic Homeostasis

Hal E. Broxmeyer, PhD, Maegan L. Capitano, PhD, Liang Zhao, PhD, Scott Cooper, MAS, Charles S. Abrams, MD
Journal: Blood
Blood (2015) 126 (23): 780.
https://doi.org/10.1182/blood.V126.23.780.780
Published: 2015