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Journal Articles

HLA-DRB1 Hed Is Associated with Improved Survival and Decreased Relapse in Patients with Hematologic Malignancies Following Allogeneic Hematopoietic Stem Cell Transplant

Christine Camacho-Bydume, Tao Wang, Diego Chowell, Chirag Krishna, Brian C. Shaffer, Steven Marsh, Sophie Paczesny, Shahinaz M. Gadalla, Meilun He, Yung-Tsi Bolon, Stephen R. Spellman, Stephanie J. Lee, Katharine C. Hsu

Blood (2023) 142 (Supplement 1): 2232.

https://doi.org/10.1182/blood-2023-179543

Published: 2023

Journal Articles

Early Prognostic Biomarkers of Non-Relapse Mortality in Allogeneic Mismatched Unrelated Hematopoietic Cell Transplantation

Trent Wang, Anna Crawford, Denggang Fu, Elizabeth Hill, Antonio M. Jimenez Jimenez, Krishna V. Komanduri, Sophie Paczesny

Blood (2023) 142 (Supplement 1): 3570.

https://doi.org/10.1182/blood-2023-180944

Published: 2023

Journal Articles

Sinusoidal Obstruction Syndrome (SOS) Biomarkers-Derived Predictive Model to Individualize SOS Preemption in Patients Undergoing Allogeneic Stem Cell Transplant

Sophie Paczesny, Iztok Hozo, Benjamin Djulbegovic

Blood (2023) 142 (Supplement 1): 4895.

https://doi.org/10.1182/blood-2023-172813

Published: 2023

Journal Articles

Janus Kinase (JAK) 1 Inhibition Results in Significant Changes in Serum Proteins and Peripheral T-Cell Populations That Correlated with Clinical Scores in Chronic Graft Versus Host Disease (GVHD) Patients (an Analysis from GRAVITAS-309)

Michael Pratta, Angelina Volkova, Maureen Bleam, Rodica Morariu-Zamfir, Beth Rumberger, Stephen Douglass, Susan H. Smith, Valkal Bhatt, John Galvin, Annie Im, Sophie Paczesny, Kirk R. Schultz, Steven Z. Pavletic

Blood (2023) 142 (Supplement 1): 2197.

https://doi.org/10.1182/blood-2023-174955

Published: 2023

Journal Articles

Machine Learning Validates Risk Biomarkers of Chronic Graft-Versus-Host Disease in 936 Patients from BMT CTN 0201 & 1202 Cohorts

Michael J Martens, Jianqun Kou, Brent R. Logan, Sophie Paczesny

Blood (2023) 142 (Supplement 1): 479.

https://doi.org/10.1182/blood-2023-182438

Published: 2023

Journal Articles

Novel Chemical Series of Anti-ST2 Small Molecules Suppress Allogeneic T Cells Proliferation While Increasing Treg Cells and Improve Gvhd and Survival In Vivo

Chao-Yie Yang, Xinrui Yuan, Hua Jiang, Jason C. Rech, Denggang Fu, Aaron Robida, Krishani Rajanayake, Hebao Yuan, Bo Wen, Duxin Sun, Krishnapriya Chinnaswamy, Jeanne A. Stuckey, Sophie Paczesny

Blood (2022) 140 (Supplement 1): 10675–10677.

https://doi.org/10.1182/blood-2022-163374

Published: 2022

Journal Articles

Single Cell Analysis Identifies Immune Marker IL4I1 As Critical for Leukemogenesis and Immunity

Denggang Fu, Hua Jiang, Sophie Paczesny

Blood (2022) 140 (Supplement 1): 8582–8583.

https://doi.org/10.1182/blood-2022-167399

Published: 2022

Journal Articles

Genetic testing in severe aplastic anemia is required for optimal hematopoietic cell transplant outcomes

Blood (2022) 140 (8): 909–921.

https://doi.org/10.1182/blood.2022016508

Published: 2022

Includes: Supplemental data

Journal Articles

A core group of structurally similar HLA-DPB1 alleles drives permissiveness after hematopoietic cell transplantation

Esteban Arrieta-Bolaños, Pietro Crivello, Meilun He, Tao Wang, Shahinaz M. Gadalla, Sophie Paczesny, Steven G. E. Marsh, Stephanie J. Lee, Stephen R. Spellman, Yung-Tsi Bolon, Katharina Fleischhauer

Blood (2022) 140 (6): 659–663.

https://doi.org/10.1182/blood.2022015708

Published: 2022

Includes: Supplemental data

Journal Articles

HLA-DQ + CD4 help = graft-versus-tumor effect

Alan Bidgoli, Sophie Paczesny

Blood (2022) 139 (20): 2999–3000.

https://doi.org/10.1182/blood.2022016117

Published: 2022

Journal Articles

HLA informs risk predictions after haploidentical stem cell transplantation with posttransplantation cyclophosphamide

Blood (2022) 139 (10): 1452–1468.

https://doi.org/10.1182/blood.2021013443

Published: 2022

Includes: Supplemental data

Journal Articles

Signatures of GVHD and relapse after posttransplant cyclophosphamide revealed by immune profiling and machine learning

Shannon R. McCurdy, Vedran Radojcic, Hua-Ling Tsai, Ante Vulic, Elizabeth Thompson, Sanja Ivcevic, Christopher G. Kanakry, Jonathan D. Powell, Brian Lohman, Djamilatou Adom, Sophie Paczesny, Kenneth R. Cooke, Richard J. Jones, Ravi Varadhan, Heather J. Symons, Leo Luznik

Blood (2022) 139 (4): 608–623.

https://doi.org/10.1182/blood.2021013054

Published: 2022

Includes: Supplemental data

Journal Articles

Haploidentical Vs. Matched Unrelated Donor Transplants Using Post-Transplant Cyclophosphamide for Lymphoma: A Joint CIBMTR/EBMT Study

Alberto Mussetti, Abraham S. Kanate, Tao Wang, Meilun He, Mehdi Hamadani, Hervé Finel, Sr., Ariane Boumendil, Sr., Bertram Glass, Luca Castagna, Didier Blaise, Steven G.E. Marsh, Sophie Paczesny, Shahinaz M. Gadalla, Peter Dreger, Stephen R. Spellman, Stephanie J. Lee, Yung-Tsi Bolon, Anna Sureda

Blood (2021) 138 (Supplement 1): 174.

https://doi.org/10.1182/blood-2021-151197

Published: 2021

Journal Articles

Impact of HLA Molecular Mismatch on Haploidentical Hematopoietic Stem Cell Transplantation: A Center for International Blood and Marrow Transplant Research Study

Jun Zou, Tao Wang, Yung-Tsi Bolon, Shahinaz M. Gadalla, Steven G.E. Marsh, Michelle Kuxhausen, Meilun He, Sophie Paczesny, Stephen R. Spellman, Stephanie J. Lee, Stefan O. Ciurea

Blood (2021) 138 (Supplement 1): 3917.

https://doi.org/10.1182/blood-2021-146847

Published: 2021

Journal Articles

Immunotherapy Targeting ST2/IL-33 Signaling in Myeloid Leukemia Stem Cells

Denggang Fu, Hua Jiang, Alan Long, Hong fen Guo, Maegan L. Capitano, Baskar Ramdas, Reuben Kapur, Nai-Kong V. Cheung, Sophie Paczesny

Blood (2021) 138 (Supplement 1): 23.

https://doi.org/10.1182/blood-2021-149672

Published: 2021

Journal Articles

Single HLA Class I Mismatches with High Peptide Divergence in the Graft-Versus-Host Direction Are Associated with Inferior Survival after 9/10 HLA-Matched UD-HCT: A Retrospective Study from the CIBMTR

Pietro Crivello, Esteban Arrieta-Bolanos, Meilun He, Tao Wang, Shahinaz M. Gadalla, Sophie Paczesny, Steven G.E. Marsh, Stephanie J. Lee, Stephen R. Spellman, Yung-Tsi Bolon, Katharina Fleischhauer

Blood (2021) 138 (Supplement 1): 97.

https://doi.org/10.1182/blood-2021-152792

Published: 2021

Journal Articles

A Refined Model of HLA-DP Permissiveness Improves Stratification of Acute Graft-Versus-Host Disease Risks after Unrelated Hematopoietic Cell Transplantation: A Retrospective Study from the CIBMTR

Esteban Arrieta-Bolanos, Pietro Crivello, Meilun He, Tao Wang, Shahinaz M. Gadalla, Sophie Paczesny, Steven G.E. Marsh, Stephanie J. Lee, Stephen R. Spellman, Yung-Tsi Bolon, Katharina Fleischhauer

Blood (2021) 138 (Supplement 1): 2890.

https://doi.org/10.1182/blood-2021-146957

Published: 2021

Journal Articles

Whole Exome Sequencing in Severe Aplastic Anemia Identifies Unrecognized Inherited Subset with Inferior Survival after Hematopoietic Cell Transplant

Lisa J. McReynolds, Maryam Rafati, Youjin Wang, Bari Ballew, Valencia Owens, Jung Kim, Neal D. Freedman, Brian Carter, Sarah Strollo, Casey Dagnall, Belynda Hicks, Bin Zhu, Kristine Jones, Sophie Paczesny, Steven G.E. Marsh, Stephen R. Spellman, Stephanie J. Lee, Sharon A. Savage, Shahinaz M. Gadalla

Blood (2021) 138 (Supplement 1): 605.

https://doi.org/10.1182/blood-2021-146982

Published: 2021

Journal Articles

Improving Donor Selection for Haploidentical Stem Cell Transplantation with Post-Transplant Cyclophosphamide through Selective HLA-Mis/Matching

Ephraim J. Fuchs, MD MBA, Shannon R McCurdy, MD, Scott R. Solomon, MD, Tao Wang, PhD, Michelle Kuxhausen, MS, Yvette L Kasamon, MD, MHD Monzr Al Malki, MD, Shahinaz Gadalla, MD PhD, Sophie Paczesny, MDPhD, Steven GE Marsh, BSc, PhD ARCS, Bronwen E. Shaw, PhD MRCP, FRCPath, Stephen R. Spellman, MS, Stephanie J. Lee, MDMPH, Effie Petersdorf, MD

Blood (2020) 136 (Supplement 1): 24–26.

https://doi.org/10.1182/blood-2020-140433

Published: 2020

Journal Articles

HLA-B leads survival after HCT

Sophie Paczesny

Blood (2020) 136 (3): 267–268.

https://doi.org/10.1182/blood.2020006878

Published: 2020

NARROW

HLA-DRB1 Hed Is Associated with Improved Survival and Decreased Relapse in Patients with Hematologic Malignancies Following Allogeneic Hematopoietic Stem Cell Transplant

Early Prognostic Biomarkers of Non-Relapse Mortality in Allogeneic Mismatched Unrelated Hematopoietic Cell Transplantation

Sinusoidal Obstruction Syndrome (SOS) Biomarkers-Derived Predictive Model to Individualize SOS Preemption in Patients Undergoing Allogeneic Stem Cell Transplant

Janus Kinase (JAK) 1 Inhibition Results in Significant Changes in Serum Proteins and Peripheral T-Cell Populations That Correlated with Clinical Scores in Chronic Graft Versus Host Disease (GVHD) Patients (an Analysis from GRAVITAS-309)

Machine Learning Validates Risk Biomarkers of Chronic Graft-Versus-Host Disease in 936 Patients from BMT CTN 0201 & 1202 Cohorts

Novel Chemical Series of Anti-ST2 Small Molecules Suppress Allogeneic T Cells Proliferation While Increasing Treg Cells and Improve Gvhd and Survival In Vivo

Single Cell Analysis Identifies Immune Marker IL4I1 As Critical for Leukemogenesis and Immunity

Genetic testing in severe aplastic anemia is required for optimal hematopoietic cell transplant outcomes

A core group of structurally similar HLA-DPB1 alleles drives permissiveness after hematopoietic cell transplantation

HLA-DQ + CD4 help = graft-versus-tumor effect

HLA informs risk predictions after haploidentical stem cell transplantation with posttransplantation cyclophosphamide

Signatures of GVHD and relapse after posttransplant cyclophosphamide revealed by immune profiling and machine learning

Haploidentical Vs. Matched Unrelated Donor Transplants Using Post-Transplant Cyclophosphamide for Lymphoma: A Joint CIBMTR/EBMT Study

Impact of HLA Molecular Mismatch on Haploidentical Hematopoietic Stem Cell Transplantation: A Center for International Blood and Marrow Transplant Research Study

Immunotherapy Targeting ST2/IL-33 Signaling in Myeloid Leukemia Stem Cells

Single HLA Class I Mismatches with High Peptide Divergence in the Graft-Versus-Host Direction Are Associated with Inferior Survival after 9/10 HLA-Matched UD-HCT: A Retrospective Study from the CIBMTR

A Refined Model of HLA-DP Permissiveness Improves Stratification of Acute Graft-Versus-Host Disease Risks after Unrelated Hematopoietic Cell Transplantation: A Retrospective Study from the CIBMTR

Whole Exome Sequencing in Severe Aplastic Anemia Identifies Unrecognized Inherited Subset with Inferior Survival after Hematopoietic Cell Transplant

Improving Donor Selection for Haploidentical Stem Cell Transplantation with Post-Transplant Cyclophosphamide through Selective HLA-Mis/Matching

HLA-B leads survival after HCT

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American Society of Hematology

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ASH Publications

American Society of Hematology

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